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Oliveira, Samanta V.,Vellei, Renata S.,Heguedusch, Daniele,Domaneschi, Carina,Costa, Claudio,Gallo, Camila de Barros Korean Academy of Oral and Maxillofacial Radiology 2021 Imaging Science in Dentistry Vol.51 No.-
Tooth extraction after head and neck radiotherapy exposes patients to an increased risk for osteoradionecrosis of the jaw. This study reports the results of a radiographic analysis of bone neoformation after tooth extraction in a case series of patients who underwent radiation therapy. No patients developed osteoradionecrosis within a follow-up of 1 year. Complete mucosal repair was observed 30 days after surgery, while no sign of bone formation was observed 2 months after the dental extractions. Pixel intensity and fractal dimension image analyses only showed significant bone formation 12 months after the tooth extractions. These surgical procedures must follow a strict protocol that includes antibiotic prophylaxis and therapy and complete wound closure, since bone formation at the alveolar socket occurs at a slower pace in patients who have undergone head and neck radiotherapy.
Oliveira, Livia Maria Lopes de,Souza, Camila Agra,Cunha, Sinara,Siqueira, Rafael,Vajgel, Bruna de Carvalho Farias,Cimoes, Renata Korean Academy of Periodontology 2021 Journal of Periodontal & Implant Science Vol.51 No.-
Purpose: This systematic review aimed to compare the efficacy, defined in terms of the mean percentage of root coverage (mRC), of surgical treatment approaches combined with adhesive restorations of non-carious cervical lesions (NCCLs) to that of root coverage alone in patients with a single gingival recession (GR) and NCCL. Methods: A literature search was conducted to identify longitudinal studies reporting the mRC following treatment for the correction of GR defects associated with NCCLs using a combination of surgical and restorative techniques in systemically and periodontally healthy patients. Results: The search resulted in the retrieval of 12,409 records. Seven publications met the inclusion criteria for the qualitative synthesis of data. The mRCs ranged from 69% to 97%. In the medium term, the gingival margin position was more stable when a connective tissue graft (CTG) was used, independently of whether restoration of teeth with NCCLs was performed. Conclusions: The strength of the evidence was limited by methodological heterogeneity in terms of study design as well as the unit and period of analysis, which precluded a metaanalysis. Although no definitive conclusion could be drawn due to the lack of sufficient evidence to estimate the effectiveness of the interventions, CTG-based procedures contributed to gingival margin stability regardless of the performance of restoration to treat NCCLs.
Influence diagnostics for skew-t censored linear regression models
Oliveira Marcos S,Oliveira Daniela CR,Lachos Victor H 한국통계학회 2023 Communications for statistical applications and me Vol.30 No.6
This paper proposes some diagnostics procedures for the skew-t linear regression model with censored response. The skew-t distribution is an attractive family of asymmetrical heavy-tailed densities that includes the normal, skew-normal and student's-t distributions as special cases. Inspired by the power and wide applicability of the EM-type algorithm, local and global influence analysis, based on the conditional expectation of the complete-data log-likelihood function are developed, following Zhu and Lee's approach. For the local influence analysis, four specific perturbation schemes are discussed. Two real data sets, from education and economics, which are right and left censoring, respectively, are analyzed in order to illustrate the usefulness of the proposed methodology.
Weighted sums of associated variables
Oliveira, Paulo Eduardo 한국통계학회 2012 Journal of the Korean Statistical Society Vol.41 No.4
We study the convergence of weighted sums of associated random variables. The convergence for the typical $n^{1/p}$ normalization is proved assuming finiteness of moments somewhat larger than p, but still smaller than 2, together with suitable control on the covariance structure described by a truncation that generates covariances that do not grow too quickly. We also consider normalizations of the form $n^{1/p}log^{1/{\gamma}}n$, where q is now linked with the properties of the weighting sequence. We prove the convergence under a moment assumption than is weaker that the usual existence of the moment-generating function. Our results extend analogous characterizations known for sums of independent or negatively dependent random variables.
Oliveira, Matheus L.,Tosoni, Guilherme M.,Lindsey, David H.,Mendoza, Kristopher,Tetradis, Sotirios,Mallya, Sanjay M. Korean Academy of Oral and Maxillofacial Radiology 2014 Imaging Science in Dentistry Vol.44 No.4
Purpose: To assess the influence of anatomic location on the relationship between computed tomography (CT) number and X-ray attenuation in limited and medium field-of-view (FOV) scans. Materials and Methods: Tubes containing solutions with different concentrations of $K_2HPO_4$ were placed in the tooth sockets of a human head phantom. Cone-beam computed tomography (CBCT) scans were acquired, and CT numbers of the $K_2HPO_4$ solutions were measured. The relationship between CT number and $K_2HPO_4$ concentration was examined by linear regression analyses. Then, the variation in CT number according to anatomic location was examined. Results: The relationship between $K_2HPO_4$ concentration and CT number was strongly linear. The slopes of the linear regressions for the limited FOVs were almost 2-fold lower than those for the medium FOVs. The absolute CT number differed between imaging protocols and anatomic locations. Conclusion: There is a strong linear relationship between X-ray attenuation and CT number. The specific imaging protocol and anatomic location of the object strongly influence this relationship.
Oliveira Ludmila Smith de Jesus,Bragança Rafaella Mariana Fontes de,Sarkis-Onofre Rafael,Faria-e-Silva André Luis 대한치과보존학회 2021 Restorative Dentistry & Endodontics Vol.46 No.3
Objectives: This systematic review evaluated the efficacy of the supplementary use of the XP-endo Finisher on bacteria content reduction in the root canal system. Materials and Methods: In-vitro studies evaluating the use of the XP-endo Finisher on bacteria content were searched in four databases in July 2020. Two authors independently screened the studies for eligibility. Data were extracted, and risk of bias was assessed. Data were meta-analyzed by using random-effects model to compare the effect of the supplementary use (experimental) or not (control) of the XP-endo Finisher on bacteria counting reduction, and results from different endodontic protocols were combined. Four studies met the inclusion criteria while 1 study was excluded from the meta-analysis due to its high risk of bias and outlier data. The 3 studies that made it to the meta-analysis had an unclear risk of bias for at least one criterion. Results: No heterogeneity was observed among the results of the studies included in the meta-analysis. The study excluded from the meta-analysis assessing the bacteria counting deep in the dentin demonstrated further bacteria reduction upon the use of the XP-endo Finisher. Conclusions: This systematic review found no evidence supporting the supplementary use of the XP-endo Finisher on further bacteria counting the reduction in the root canal.
Antimicrobial peptides of the genus Capsicum: a mini review
Oliveira Arielle Pinheiro Bessiatti Fava,Resende Larissa Maximiano,Rodrigues Rosana,de Oliveira Mello Érica,Taveira Gabriel Bonan,de Oliveira Carvalho André,Gomes Valdirene Moreira 한국원예학회 2022 Horticulture, Environment, and Biotechnology Vol.63 No.4
Antimicrobial peptides (AMPs) have been characterized in various organs and plant species. However, few studies have investigated AMPs in the genus Capsicum , especially their biological activities and mechanism of action. AMPs are small proteins isolated primarily from plants and animals. AMPs are of great interest to researchers because of their potent antimicrobial activity due to their ability to interact with cell membranes. While some AMPs participate in innate immune response by providing a rapid line of defense against infection, others may bolster plant defense against certain pests and pathogens. The genus Capsicum contains a myriad of AMPs involved in plant defense with the potential for new antimicrobial molecules. In recent years, our group and others have isolated and characterized AMPs from seeds, fruits, leaves and roots of Capsicum plants. Herein, we describe the diff erent AMP families, like defensins, lipid transfer proteins (LTPs), thionins, proteinase inhibitors, and others, present in the genus Capsicum . We also discuss the current knowledge of their antimicrobial activity, mechanism of action, and possible uses as antimicrobial molecules and in plant biotechnology.
Patrícia Martinez-Oliveira,Luísa Zuravski,Micaela Federizzi de Oliveira,Deise Jaqueline Ströher,Ritiéle Pinto Coelho,Bruna Cocco Pilar,Luís Flávio Souza de Oliveira,Jacqueline da Costa Escobar Piccoli 한국식품영양과학회 2021 Journal of medicinal food Vol.24 No.6
Yacon is an Andean plant that has been used in folk medicine for its medicinal properties. The beneficial effects of this plant are possibly due to the high content of phenolic compounds present in its leaves and roots. This study evaluated the in vitro toxicity of the hydroalcoholic extract of leaves and roots from yacon (1, 10, 50, and 100 μg/mL) through cell viability tests, genotoxic and mutagenic activity in leukocytes culture cells; and cytotoxicity and apoptosis cell death (1, 10, 50, 100, and 500 μg/mL) in cell line originally established from the primary mouse embryonic fibroblast cells that were cultured by the designated protocol, so-called 3T3 protocol “3-day transfer, inoculum 3 × 105 cells” (3T3 cell line). No mutagenic and cytotoxic activities were observed in leukocyte cultures. Cytotoxic activity was evidenced in the highest concentrations of yacon leaf extract (50 and 100 μg/mL), whereas all concentrations tested with yacon leaf extract there was induction for apoptosis in the 3T3 cells. Genotoxic potential was observed only at higher doses of leaf (50 and 100 μg/mL) and root (100 μg/mL) extract. These results suggest that yacon leaf at high concentrations may present toxic potential showing concentration-dependent behavior; however, in vivo studies should be performed to validate these results.
Gleidson Benevides de Oliveira,Helio Noberto de Araújo Júnior,Carlos Eduardo Bezerra de Moura,Phelipe Oliveira Favaron,Alexsandra Fernandes Pereira,Moacir Franco de Oliveira 대한수의학회 2023 Journal of Veterinary Science Vol.24 No.5
Background: Hystricomorpha rodents display a similar placentation model to humans. The present study was carried out considering the scarcity of information concerning the placental development in agouti. Objective: Describe the microscopy of the placenta, subplacenta and yolk sac of agoutis in early pregnancy and report on the inversion of the yolk sac. Methods: Fifteen females between the 14th–32nd day of gestation were used following euthanasia. Gestational buttons were collected, fixed, processed, stained to optical microscopy or immunohistochemistry. Results: Chorioallantoic placenta (CP) ranged from conical to a half-sphere, as follows: from the 14th to 17th day, the CP displays an inverted “V” shape, predominantly formed by cytotrophoblasts; from 20 to 22 days, formed almost entirely by cytotrophoblasts; at 28 days, a half sphere, with distinct lobes and interlobular area, numerous maternal gaps delimited by syncytiotrophoblasts and trophoblast giant cells; at 32 days, globose and undergoing the maturation process. Subplacenta, located between decidua and CP, initially presents septa consisting of simple columnar epithelium and after 17 days, comprising stratified epithelium. Visceral yolk sac (VYS) is attached to two CP projections between 14 and 17 days, formed by a simple cubic epithelium and inverted. Between 20 and 22 days, the epithelium displays apical villous projections with cytoplasmic vacuoles and a vascularized mesoderm. After the 24th day, the VYS near the placenta is pleated, very vascularized and villous, with decreased villi sizes further away from the placenta. Conclusion: The agouti CP displays similar characteristics to other hystricomorpha, including placenta lobulation, a subplacenta and an inverted vitelline placenta.