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Nu Ri Oh,Ae Rang Hwang,Ja In Jeong,Sung Hyun Park,Jin Seok Yang,Yong-Ho Lee 대한의생명과학회 2012 Biomedical Science Letters Vol.18 No.1
This study was to investigate the effects of high-fat diet feeding for a very long period of time on gene expression of inflammatory cytokines in mouse adipose tissue and to determine whether caloric restriction (CR) or insulin sensitizer treatment changes the cytokine gene expressions even in obese mice fed a high-fat diet for a very long term-period. Gene expression levels of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and monocyte chemoattractant protein-1 (MCP-1) were examined by real-time PCR in subcutaneous abdominal adipose tissue (SubQ) from obese and non-obese male C57BL/6 mice at 16, 26, 36, 47, and 77 weeks of age on either normal diet (ND) or high-fat diet (HFD) after starting at 6 weeks of age. In addition, gene expression levels of TNF-α, IL-6 and MCP-1 were determined in SubQ before and after rosiglitazone treatment or CR on 47-week-old obese mice. The results demonstrated that gene expression levels of TNF-α, IL-6 and MCP-1 were significantly increased with aging in SubQ of mice in both groups of diet. MCP-1 gene expression of SubQ in all ages tested was significantly or marginally increased in mice on HFD compared with ND. While TNF-α expression was significantly reduced by rosiglitazone, IL-6 and MCP-1 were significantly decreased by CR. The basic data in this study will be useful for characterizing the C57BL/6 mouse as an animal model of obesity induced by high-fat diet feeding for a very long period of time, and a better understanding of inflammatory cytokine regulation in diet induced obesity which may facilitate the development of new therapeutic strategies to prevent the complications of obesity.
Polystyrene Nanosphere Lithography Improved by the Insertion of a Sacrificial Polyimide Film
( Nu Ri Oh ),( Tae Jin Song ),( Sung Keun Lim ),( Chong Seung Yoon ) 대한금속재료학회 ( 구 대한금속학회 ) 2005 ELECTRONIC MATERIALS LETTERS Vol.1 No.2
A 2-dimensional hexagonal array of uniformly sized nano-holes, whose average size can be potentially changed from 50 nm to 240 nm, was fabricated using the etched nanosphere lithography (NSL) method. The conventional NSL method utilizing polystyrene beads (PS) coated on a Si substrate often suffers from a loss of uniformity during the etching of the PS beads. It was demonstrated that the uniformity of the hole size and position can be greatly improved by inserting a polyimide (PI) film between the Si substrate and the PS beads. A sufficiently thick (~40 run) PI film can act as a sacrificial layer, minimizing the rebound of the plasma during the reactive ion etching of the PS beads. Hence, the etching of the PS beads stabilized by the PI film can be used to determine the final desired size of the hole. The periodicity of the pattern can also be selected by changing the initial PS bead diameter.
Nu-ri Kim,Sun-hee Ahn,Gyeong-tae Gwak,Hwa-ik Yoo,Oh-yun Kwon 한국전문물리치료학회 2021 한국전문물리치료학회지 Vol.28 No.3
Background: The serratus posterior inferior (SPI) muscle originates from the spinous pro-cess of T11-L2 and inserts at the lower border of the 9–12th ribs. This muscle is involved in thoracolumbar rotation and stability. Several positions can be used to improve trunk stability; the quadruped position is a good position for easily maintaining a neutral spine. In particular, during one arm lifting, various muscles act to maintain a neutral trunk position, and the SPI is one of these muscles. If trunk stability is weakened, uncontrolled trunk rotation may occur at this time. Tape can be used to increase trunk stability. There have been no studies on the effect of taping applied to the SPI muscle on thoracolumbar junction (TLJ) stability. Objects: This study compared the TLJ rotation angle between three different conditions (without taping, transverse taping, and SPI muscle direction taping). Methods: Thirty subjects were recruited to the study (18 males and 12 females). The TLJ rota-tion angle was measured during one arm lifting in a quadruped position (ALQP). Two taping methods (transverse and SPI muscle direction taping) were applied, and the TLJ rotation angle was measured in the same movement. Results: SPI muscle direction taping significantly reduced TLJ rotation compared to that with-out taping (p < 0.001) and with transverse taping (p < 0.001). There was a significant dif-ference in the TLJ rotation angle between transverse taping and SPI muscle direction taping (p < 0.017). Conclusion: SPI muscle direction taping reduces the TLJ rotation angle during ALQP. There-fore, SPI muscle direction taping is one method to improve TLJ stability and reduce uncon-trolled TLJ rotation during ALQP.
고관절 외전 각도가 리버스 하이퍼 익스텐션 운동 시 근활성도에 미치는 영향
오정헌(Oh, Jeong-Heon),한누리(Han, Nu-Ri),서태범(Seo, Tae-Beom) 한국체육과학회 2021 한국체육과학회지 Vol.30 No.6
The purpose of this study was to investigate whether different hip abduction angles might alternate hip extensor muscle activity in reverse hyperextension (RHE) exercise. Fourteen healthy male subjects performed RHE in 4 hip abduction angles (-10°, 0°, 15°, and 30°). Muscle activities of longissimus, gluteus maximus, gluteus medius, biceps femoris, semitendinosus, and adductor magnus were measured by surface electromyography device. One-way repeated ANOVA was used to analyze the results from each angle of muscle and the ratio of muscle activation. During the concentric phase of RHE, gluteus medius activation was greater at 15° and 30° of hip abduction angles (p<.001) than at -10 and 0°, while biceps femoris was greatest at -10° (p<.001) followed by 0°, 15°, and 30° of hip abduction angles. During the eccentric phase of RHE, gluteus medius activation was greater at 15° and 30° of hip abduction angles (p<.003) than -10°, while biceps femoris was greatest at -10° (p<.001) followed by 15° and 30°. Our findings suggest that RHE of hip abduction at 15° and 30° might be the most appropriate angle for maximizing gluteal muscle activation.
과산화수소 처리에 의한 토양 유기물 분해 반응의 온도 변화
백누리 ( Nu-ri Baek ),정영재 ( Young-jae Jeong ),서보성 ( Bo-seong Seo ),이수진 ( Su-jin Lee ),이승민 ( Seung-min Lee ),김한중 ( Han-joong Kim ),최현수 ( Hyeon-soo Choi ),오효림 ( Hyo-rim Oh ),박서우 ( Se-ou Park ),신은서 ( Eun-se 한국환경농학회 2021 한국환경농학회 학술대회집 Vol.2021 No.-
토양 유기물은 토양 건강의 가장 중요한 지표이다. 토양 유기물은 대표적으로 원소분석기를 이용한 산화법과 Walkley Black (WB) 방법을 이용한 습식분해법으로 분석할 수 있다. 하지만, 원소 분석기는 고가의 장비이고, 중크롬산칼륨과 황산 등을 사용하는 WB 방법은 실험의 위험성과 폐액발생 등의 문제가 있다. 따라서, 보다 간편하고 안전하게 토양 유기물 함량을 분석할 수 있는 방법을 개발할 필요가 있다. 본 연구에서는 환경 독성이 거의 없는 과산화수소(산화제)와 토양을 반응시켜, 토양 유기물 산화에 의해 발생하는 열에 의한 온도 상승을 이용한 토양 유기물 함량 분석법 개발을 위한 예비 실험을 수행하였다. 토양(5.52 g C kg<sup>-1</sup>) 0.25-10 g (탄소로 1.4-55.2 mg)을 250mL 삼각플라스크에 담고 30% 과산화수소 20 mL를 투입하여 토양 유기물을 산화시켰다. 토양 1 g 이상에서 반응 온도가 유의하게 증가하였고, 토양 5 g 이상에서는 반응 10분 이내에 온도가 85-90℃ 까지 상승하였다. 토양 투입량(탄소함량)과 최대 온도 간에 결정계수 0.96 이상의 상관관계가 있었다. 과산화수소의 산화 반응 후 잔류 토양의 탄소함량을 분석한 결과 초기 탄소의 10-14%가 산화되었으며, 토양 투입량이 1 g에서 10 g으로 증가함에 따라 산화율은 66%에서 24%로 감소하였다. 본 연구 결과를 통해 토양 유기물 함량에 따라 과산화수소와의 산화 반응에서 발생하는 열에 의한 온도 차이가 뚜렷하게 나타나는 것을 확인하였다. 향후, 이를 활용하여 토양 유기물 함량을 간편하게 분석할 수 있는 기법 개발이 가능할 것으로 기대된다.