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Thi Binh Nguyen Nguyen,Thi Kieu Diem Nguyen,Van Hue Trương,Thi Tuyet Ngoc Tran,van Bao Thang Phan,Thi Tuyen Nguyen,Hoang Bach Nguyen,Viet Quynh Tram Ngo,Van Tuan Mai,Paola Molicotti 질병관리본부 2023 Osong Public Health and Research Persptectives Vol.14 No.5
Objectives: Tuberculosis (TB) and drug-resistant TB (DR-TB) are national health burdens in Vietnam. In this study, we investigated the prevalence of rifampicin (RIF) and/or isoniazid (isonicotinic acid hydrazide, INH) resistance in patients with suspected TB, and applied appropriate techniques to help rapidly target DR-TB. Methods: In total, 1,547 clinical specimens were collected and cultured using the BACTEC MGIT system (Becton Dickinson and Co.). A resazurin microtiter assay (REMA) was used to determine the proportions of RIF and/or INH resistance. A real-time polymerase chain reaction panel with TaqMan probes was employed to identify the mutations of rpoB and katG associated with DR-TB in clinical isolates. Genotyping of the identified mutations was also performed. Results: A total of 468 Mycobacterium tuberculosis isolates were identified using the REMA. Of these isolates, 106 (22.6%) were found to be resistant to 1 or both antibiotics. Of the resistant isolates, 74 isolates (69.8%) were resistant to isoniazid (INH) only, while 1 isolate (0.94%) was resistant to RIF only. Notably, 31 isolates (29.24%) were resistant to both antibiotics. Of the 41 phenotypically INH-resistant isolates, 19 (46.3%) had the Ser315Thr mutation. There were 8 different rpoB mutations in 22 (68.8%) of the RIF-resistant isolates. The most frequently detected mutations were at codons 531 (37.5%), 526 (18.8%), and 516 (6.3%). Conclusion: To help prevent new cases of DR-TB in Vietnam, it is crucial to gain a comprehensive understanding of the genotypic DR-TB isolates.
Corrosion of Reinforcing Steel : A Discussion on Evaluation Methods
Hue, Nguyen Viet,Tuong, Phan Van,Quang Hung, Nguyen Viet 한국부식방식학회 2002 Corrosion Science and Technology Vol.31 No.4
The last effort of technologists is to obtain the best quality of concrete both mechanical and durability (service-life) in severe environments as marine or industrial. Problem is how to evaluate the durability of concrete. A lot of methods have showed being able to apply for evaluation of reinforcing steel corrosion, but there are a number of limitations with each method. Through some results obtained from works of authors and literature, a discussion was made in this paper with purpose to select the suitable methods for measurement and evaluation of reinforcing steel corrosion in concrete.
The Relationship Between Chromium Content and Erosion-Corrosion Resistance of Fe-Cr-C Alloy System
Hue, Nguyen Viet,Phuong, Doan Dinh,Tich, Nguyen Van,Binh, Hoang Thi 한국부식방식학회 2002 Corrosion Science and Technology Vol.31 No.1
In order to determine the influence of chromium on erosian-comsian coefficient of alloy in acid media, experiments were performed with chromium content in the range of 12-33% in different typical erosion-corrosion environments such as solution of sand, solution of sand with free acid in pH 2-7. The erosion-corrosion coefficient was evaluated by Apparatus for abrasion-corrosion testing. Wear coetr-icient, K, was calculated by formula: K=ΔMetalon/ΔMalloy Testing results were showed that the alloy with composition (%): Cr=28-30; C=1.8-2.0; Mn=2.5 - 3.0; is the optimum for manufacturing details resistant erosion-corrosion in media upto pH=2-3. This alloy is used successfully to produce details for sand-pumps, minerals processing cyclones.