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Nguyen Van Du,이순일,서원선,Nguyen Minh Dat,맹은지,임창현,Jamil Ur Rahman,김명호 한국전기전자재료학회 2015 Transactions on Electrical and Electronic Material Vol.16 No.6
The n-type Hf0.25Zr0.25Ti0.5NiSn0.998Sb0.002 Half-Heusler (HH) alloy composition was prepared by using the induction melting method in addition to the mechanical grinding, annealing, and spark plasma sintering processes. Analysis of X-ray diffraction (XRD) results indicated the formation of a pure phase HH structured compound. The electrical and thermal properties at temperatures ranging from room temperature to 718 K were investigated. The electrical conductivity increased with increasing temperatures and demonstrated nondegenerate semiconducting behavior, and a large reduction in the thermal conductivity to the value of 2.5 W/mK at room temperature was observed. With the power factor and thermal conductivity, the dimensionless figure of merit was increased with temperature and measured at 0.94 at 718 K for the compound synthesized by the induction melting process.
Performance Evaluation of 40/50 and 60/70 binder in Asphalt Mixtures
Van Hung Nguyen,Van Du Nguyen,Van Phuc Le 한국도로학회 2018 한국도로학회 학술대회 발표논문 초록집 Vol.2018 No.05
The main objective of this research study is the performance evaluation of 40/50 and 60/70 binder for asphalt mixtures in Vietnam. To accomplish the objective of this research, a dense gradation with nominal maximum aggregate size of 19.0mm is used for the asphalt mixtures. Marshall Stability (MS) test, Tensile Strength Ratio (TSR) test, Wheel Tracking (WT) test, and Dynamic modulus test are conducted to evaluate the rutting and cracking performance of 40/50 and 60/70 binder in asphalt mixtures. It was found that the Marshall stability of asphalt mixtures using 40/50 binder is about 12% higher than asphalt mixtures using 60/70 binder while the rutting resistance of the mixtures with 40/50 binder shows 2.5 times higher than 60/70 binder at 15,000 load cycles. Moreover, the TSR of asphalt concrete using 40/50 binder and 60/70 binder are approximately 95% and 79%, respectively which means that using 40/50 binder is very good for moisture damage resistance. Finally, the dynamic modulus test was done at a reference temperature of 20oC and frequency of 1,0Hz. The dynamic modulus of asphalt mixture with 40/50 binder is about 6257 MPa, which is two times higher than asphalt mixture using 60/70 binder. Based on the results of this study, it can be concluded that asphalt mixtures using 40/50 binder can improve the rutting and moisture damage resistance of asphalt concrete under high temperatures and moisture conditions significantly. It is noted that these conclusions were based on only on a limited number of samples and conditions. Further studies must be conducted to investigate the effect of 40/50 binder on fatigue cracking of asphalt pavement in the field.
Van Du Cao,Phuong phong Nguyen,Vo Quoc Khuong,Cuu Khoa Nguyen,Xuan Chuong Nguyen,Cap Ha Dang,Ngoc Quyen Tran 대한화학회 2014 Bulletin of the Korean Chemical Society Vol.35 No.9
In this paper ultrafine copper nanoparticles (CuNPs) were prepared from copper salt via chemical reduction method with sodium citrate dispersant and polyvinylalcol (PVA) capping polymer. The colloidal CuNPs were characterized by using UV–Visible spectroscopy, Transmission Electron Microscopy (TEM), and X-ray Diffraction (XRD) techniques. Our obtained results indicated that the CuNPs were produced ranging from 2 to 4 nm in diameter. The colloidal solution at 7 ppm of CuNPs exhibited a powerful antifungal activity against Corticium salmonicolor (C. Salmonicolor). Fungal killing assays showed colloid solutions containing 10 ppm of CuNPs killed entirely the cultured fungus. A highly killing activity against the fungus was also performed when the CuNPs were sprayed on pink disease-infected rubber trees. These positive results may offer a great potential to produce CuNPs-based eco-fungicide for pink disease.
Nguyen, Van Du,Min, Hyun-Ki,Kim, Chang-Sei,Han, Jiwon,Park, Jong-Oh,Choi, Eunpyo Elsevier 2019 Colloids and surfaces. B, Biointerfaces Vol.173 No.-
<P><B>Abstract</B></P> <P>An effective nanoparticle-based drug delivery platform holds great promise for non-invasive cancer therapy. This study explores the breast tumor regression <I>in vivo</I> by synergistic photothermal-chemotherapy based on liposomal nanocomplex (folic acid-gold nanorods-anticancer drug-liposome). The proposed liposomal nanocomplex can enhance the tumor targeting by functionalizing folic acid (FA) molecules on the surface of liposome that encapsulates both gold nanorods (AuNRs) and the doxorubicin (DOX) to combine the photothermal therapy and the chemotherapy, respectively. Herein, 7-nm gold nanorods were fabricated and co-encapsulated with DOX into nanoliposomes functionalized with FA, with an average diameter of 154 nm, for active targeting to the cancer cells. The experimental results showed that the FA targeting liposomes had better cellular uptake than the non-targeting liposomes (AuNRs-DOX-LPs). Especially, upon 5 min exposure to near infrared (NIR) irradiation (808 nm) triggered DOX release could be achieved to 46.38% in 60 min at pH 5.5. In addition, <I>in vitro</I> cell proliferation assays indicated that, with synergistic photothermal-chemotherapy, the targeting liposomes could significantly enhance the toxicity towards the cancer cells with the IC<SUB>50</SUB> value of 1.90 ± 0.12 μg mL<SUP>−1</SUP>. Furthermore, <I>in vivo</I> experiments on the breast tumor-bearing mice showed that the targeting liposomes could effectively inhibit the growth of the tumors using the combined strategy.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Novel folate receptor-targeted lipsomes encapsulated with small size gold nanorods and doxorubicin were developed. </LI> <LI> Triggered drug release was obtained with NIR laser irradiation. </LI> <LI> The liposomes were specifically targeted to breast cancer cells overexpressed folate receptor. </LI> <LI> The liposomes could effectively inhibit growth of breast tumor <I>in vivo</I> with the synergistic therapy. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Du, Nguyen Van,Lee, Soonil,Seo, Won-Seon,Dat, Nguyen Minh,Meang, Eun-Ji,Lim, Chang-Hyun,Rahman, Jamil Ur,Kim, Myong Ho The Korean Institute of Electrical and Electronic 2015 Transactions on Electrical and Electronic Material Vol.16 No.6
The n -type Hf<sub>0.25</sub>Zr<sub>0.25</sub>Ti<sub>0.5</sub>NiSn<sub>0.998</sub>Sb<sub>0.002</sub> Half-Heusler (HH) alloy composition was prepared by using the induction melting method in addition to the mechanical grinding, annealing, and spark plasma sintering processes. Analysis of X-ray diffraction (XRD) results indicated the formation of a pure phase HH structured compound. The electrical and thermal properties at temperatures ranging from room temperature to 718 K were investigated. The electrical conductivity increased with increasing temperatures and demonstrated nondegenerate semiconducting behavior, and a large reduction in the thermal conductivity to the value of 2.5 W/mK at room temperature was observed. With the power factor and thermal conductivity, the dimensionless figure of merit was increased with temperature and measured at 0.94 at 718 K for the compound synthesized by the induction melting process.
Nguyen, Van Du,Zheng, Shaohui,Han, Jiwon,Le, Viet Ha,Park, Jong-Oh,Park, Sukho Elsevier 2017 Colloids and surfaces Biointerfaces Vol.154 No.-
<P><B>Abstract</B></P> <P>The aim of this work is to prepare and evaluate a novel lipid-polymer hybrid liposomal nanoplatform (hyaluronic acid-magnetic nanoparticle-liposomes, HA-MNP-LPs) as a vehicle for targeted delivery and triggered release of an anticancer drug (docetaxel, DTX) in human breast cancer cells. We first synthesize an amphiphilic hyaluronic acid hexadecylamine polymer (HA-C<SUB>16</SUB>) to enhance the targeting ability of the hybrid liposome. Next, HA-MNP-LPs are constructed to achieve an average size of 189.93±2.74nm in diameter. In addition, citric acid-coated magnetic nanoparticles (MNPs) are prepared and embedded in the aqueous cores while DTX is encapsulated in the hydrophobic bilayers of the liposomes. Experiments with coumarin 6 loaded hybrid liposomes (C6/HA-MNP-LPs) show that the hybrid liposomes have superior cellular uptake in comparison with the conventional non-targeting liposomes (C6/MNP-LPs), and the result is further confirmed by Prussian blue staining. Under near-infrared laser irradiation (NIR, 808nm), the HA-MNP-LPs aqueous solution can reach 46.7°C in 10min, and the hybrid liposomes released over 20% more drug than the non-irradiated liposomes. Using a combination of photothermal irradiation and chemotherapy, the DTX-loaded hybrid liposomes (DTX/HA-MNP-LPs) significantly enhance therapeutic efficacy, with the IC<SUB>50</SUB> value of 0.69±0.10μg/mL, which is much lower than the values for DTX monotherapy. Consequently, the prepared hybrid nanoplatform may offer a promising drug delivery vehicle with selective targeting and enhanced drug release in treating CD44-overexpressing cancers.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Novel polymer-lipid nanohybrid liposomes for active tumor targeting are synthesized. </LI> <LI> Magnetic nanoparticles and drug are encapsulated for photothermal-chemotherapy. </LI> <LI> Nanohybrid liposomes significantly enhance cellular uptake to breast cancer cells. </LI> <LI> Near-infrared light can trigger drug release from the nanohybrid liposomes. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Cao, Van Du,Nguyen, Phuong Phong,Khuong, Vo Quoc,Nguyen, Cuu Khoa,Nguyen, Xuan Chuong,Dang, Cap Ha,Tran, Ngoc Quyen Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.9
In this paper ultrafine copper nanoparticles (CuNPs) were prepared from copper salt via chemical reduction method with sodium citrate dispersant and polyvinylalcol (PVA) capping polymer. The colloidal CuNPs were characterized by using UV-Visible spectroscopy, Transmission Electron Microscopy (TEM), and X-ray Diffraction (XRD) techniques. Our obtained results indicated that the CuNPs were produced ranging from 2 to 4 nm in diameter. The colloidal solution at 7 ppm of CuNPs exhibited a powerful antifungal activity against Corticium salmonicolor (C. Salmonicolor). Fungal killing assays showed colloid solutions containing 10 ppm of CuNPs killed entirely the cultured fungus. A highly killing activity against the fungus was also performed when the CuNPs were sprayed on pink disease-infected rubber trees. These positive results may offer a great potential to produce CuNPs-based eco-fungicide for pink disease.
Quyen Le Hoang Thuy To NGUYEN,Du Van NGUYEN,Ngoc Nguyen Mong CHU,Van Hong TRAN 한국유통과학회 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.11
The shift from elite education to mass education in Vietnam has met the demand for education for everybody as well as for quality human resource talent for an emerging nation. Under the resource constraint, understanding the quality dimensions of education and its priority level is important for effective and efficient policies. This study was carried out using both qualitative and quantitative methodologies to develop quality criteria and a ranking model. Two rounds of in-depth interviews were conducted with fifteen experts in the field, who were rectors, employers, and recruitment specialists to develop the quality framework applied in Vietnamese universities under total quality management (TQM), starting from the input of the senior secondary school leavers, through a teaching process to the output. The first round of interviews were unstructured questionnaires designed to explore the main factors in quality assessment model. The second round affirmed the experts’ agreement on the assessment model. Then, fuzzy logic was applied to rank eight criteria in the quality assessment model into priority order: cost, teaching and administrative staff, leadership, curriculum, student-related factors, internationalization, admissions, and campus. The results are critical for identifying the necessary actions to enhance the education quality and to further research on the optimal quality model.