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자동산화 Methyl Linoleate 가 Mouse 혈청의 효소활성에 미치는 영향 ( 급성 독성 )
백태홍,정낙승 ( Tai Hong Paik,Nak Seung Chung ) 한국유화학회 1984 한국응용과학기술학회지 Vol.1 No.1
In order to investigate the acute toxicity of autoxidized methyl linoleate(AOML) on the activity of serum enzymes in the mouse, we administered once 0.45ml of AOML to ICR strain mouse by using stomach tube. The following results were obtained: The total lactic dehydrogenase(LDH) activities in the serum of AOML group were generally increased than those of mormal group. According to electrophoresis, the activities of LDH, were increased while those of LDH, were decreased. The activities of glutamic oxaloacetic transaminase(GOT), glutamic-pyruvic transaminase(GPT) and α-amylase in the serum of AOML group were increased more than those of mormal group. The activities of alkaline phosphatase in the serum of AOML group were increased but those of isozyme were not confirmend in the normal and AOML group. In the serum protein of AOML group, albumin was increased, on the other hand r-globulin was decreased. At the peripheral blood slide smear, lymphocytes were significantly decreased but neutrophils were increased and the morphological change of erythrocytes was observed. From these results we conclude that the AOML fed to mouse influences on the activity of various serum enzymes and blood cells in the mouse.
자동산화 Methyl Linoleate가 Mouse혈청의 효소활성에 미치는 영향 (급성 독성)
Tai Hong Paik(白台鴻),Nak Seung Chung(鄭樂昇) 한국유화학회 1984 한국응용과학기술학회지 Vol.1 No.1
In order to investigate the acute toxicity of autoxidized methyl linoleate(AOML) on the activity of serum enzymes in the mouse, we administered once 0.45ml of AOML to ICR strain mouse by using stomach tube. The following results were obtained: The total lactic dehydrogenase(LDH) activities in the serum of AOML group were generally increased than those of normal group. According to electrophoresis, the activities of LDH, were increased while those of LDH, were decreased. The activities of glutamic oxaloacetic transaminase(GOT), glutamic-pyruvic transaminase(GPT) and α-amylase in the serum of AOML group were increased more than those of normal group. The activities of alkaline phosphatase in the serum of AOML group were increased but those of isozyme were not confirmed in the normal and AOML group. In the serum protein of AOML group, albumin was increased, on the other hand γ-globulin was decreased. At the peripheral blood slide smear, lymphocytes were significantly decreased but neutrophils were increased and the morphological change of erythrocytes was observed. From these results we conclude that the AOML fed to mouse influences on the activity of various serum enzymes and blood cells in the mouse.
1980年度 織員定期身體檢査에서의 化學的 檢査 結果에 對한 小考
鄭樂昇,金泰英,白仁基,高一香 인제대학교 1981 仁濟醫學 Vol.2 No.2
직원 정기신체정사에서 비교적 다항목에 걸친 화학적 검사를 전 수검자에 대하여 실시한 것은 처음으로서, 의료직의 HBsAg양성율이 일반직에 비하여 높았고, 전문의군의 총콜레스테롤치가 동연령에서의 일반인군에 비하여 높은 결과를 얻었으며, 본 검사종목에 대한 평균치 및 표준편차는 정상인 통계로서 유의한 참고가 될 수 있을것으로 기대한다. The following data are excerpts of the annual health check-up on the Seoul Paik Hospital employees carried out in September, 1980. 1.HBs Antigen detection rate. 1) 777 employees were checked by RPHA method. 33 patients (4.25%) were positive. In male 16 out of 250 (6.40%), in female 17 out of 527 (3.23%) were positive. 2) SGOT was elevated in 7 out 33 HBsAg positive(21.21%). In male 6 out 16 (37.50%), in female 1 out 17 positives (5.88%) showed elevated SGOT. 3) HBsAg was positive in 25 out 539 medical and para-medical employees (4.64%). In administrative employees 8 out 238 (3.36%) were positive. 4) Further break down of HBsAg positive rates reveals the following results: Clinical laboratry and X-ray employees 10.35%, medical staff members 8. 11% residents 5.80%, general affairs and pharmacy 4.35%, maintenance 3.51%, nurses 3.50%, admission and discharge 2,38%. kitchen 2.33%. 5) None were positive in before 19 and after 40 years. 2.ABO blood groups. Of 769 employees examined, group A 33.8%, B 26.7%, O 30.0%, AB 9.5%. 3.Biochemistry. 1) Hemoglobin vales were 15.15±2.52g/dl for male and 12.70±2.66g/dl for females. 2) Total cholesterol value showed a tendency to increase with age. 3) Staff members are composed of 36 specialists. Their total cholesterol level averaged 201.5mg/dl while other employees of the same age group averaged 181.7mg/dl. 4) The results of six tests are as follows. ◁표 삽입▷ (원문을 참조하세요)