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RISS 인기검색어
- 검색키워드
- 저자 : Nagao Michinobu (검색결과 3 건)
- 무료
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Kawakubo Masateru,Nagao Michinobu,Nakao Risako,Watanabe Eri,Yoneyama Masami,Hagiwara Nobuhisa,Sakai Shuji 아시아심장혈관영상의학회 2022 Cardiovascular Imaging Asia Vol.6 No.1
Objective: In steady-state free precession (SSFP) cine imaging, signal loss can be observed as accelerated dark flow in patients with valvular disease and decelerated dark flow (DDF) in patients with severe left ventricular (LV) dysfunction. In our study, we measured DDF with optical flow calculations and investigated the relationship between DDF and myocardial strain or intraventricular dyssynchrony. Materials and Methods: Fifty-seven consecutive patients with heart failure were retrospectively enrolled. In the short-axis orientation, the optical flow magnitude vector of the DDF was calculated over a cardiac cycle. The maximum value of the mean magnitude vector in the LV blood region was defined as the DDF index. The systolic circumferential strain (CS) of the LV free-wall, as well as the absolute difference in systolic timing of the LV free-wall and interventricular septum (LV dyssynchrony, LVD), was measured using the feature-tracking method. Spearman’s correlation coefficients (ρ) were calculated between DDF and CS or LVD. Results: Median and interquartile ranges (25th to 75th percentile) of measured DDF, CS, and LVD in 57 patients were 14.0 (10.3 to 20.4), -8.0% (-13.3 to -3.2), and 40 ms (21 to 99), respectively. There were statistically significant correlations between the values of DDF and CS as well as LVD (0.60 and 0.48; p<0.01 for both). Conclusion: Measurement of DDF may provide a specific clinical picture of myocardial strain and intraventricular dyssynchrony. Furthermore, it is possible to cost-effectively measure DDF without additional image acquisition during routine MR examination.
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Yukako Izoe,Michinobu Nagao,Koichi Chida 아시아심장혈관영상의학회 2021 Cardiovascular Imaging Asia Vol.5 No.3
Objective: Detection of coronary artery calcification (CAC) in healthy individuals and investigation of this risk factor are useful for preventing heart disease. One aim of this study was to quantify CAC using low-dose chest CT longitudinally performed for lung cancer screening. The other aim was to identify the risk factors related to CAC onset in healthy individuals. Materials and Methods: Here, 203 individuals (mean age, 53 years) who underwent health screening and CT were enrolled. A total of 1108 CT examinations (mean follow-up period, 56 months) was analyzed. CAC (mm3) was defined as a high-density area with a CT value >130 Hounsfield units along coronary arteries. Subjects with a CAC >14 mm3 were defined as CAC onset; the others were defined as non-CAC. Results: CAC onset and non-CAC were observed in 27 (13%) and 176 (87%) subjects, respectively. Age and hemoglobin A1c (HbA1c) were significantly higher and estimated glomerular filtration rate (eGFR) was significantly lower for CAC onset than for non-CAC (57.1±4.3 years vs. 55.0±5.2 years, 6.1%±1.5% vs. 5.6%±0.7%, and 70.6±12.9 mL/min vs. 73.5±11.5 mL/min, respectively). Multivariate logistic regression analysis revealed that CAC onset was significantly related to age [odds ratio (OR), 1.06; 95% confidence interval (CI), 1.03–1.10], male (OR, 1.59; 95% CI, 1.05–2.42), HbA1c level (OR, 1.77; 95% CI, 1.47–2.14), and eGFR (OR, 0.97; 95% CI, 0.95–0.99). Conclusion: CAC occurred in about 10% of healthy middle-aged subjects and is associated with early glucose intolerance and a slight decline in renal function.
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Kojima Tsukasa,Yamasaki Yuzo,Kamitani Takeshi,Yabuuchi Hidetake,Shirasaka Takashi,Shimomiya Yamato,Kondo Masatoshi,Hamasaki Hiroshi,Kato Toyoyuki,Nagao Michinobu,Honda Hiroshi 아시아심장혈관영상의학회 2019 Cardiovascular Imaging Asia Vol.3 No.1
Objective: The smallest diagnostically sufficient amount of contrast media (CM) should be used for coronary computed tomography angiography (CCTA) to minimize the risk of contrast- induced nephrotoxicity in elderly patients with coronary artery disease. The purpose of this study was to propose dynamic-CCTA using a low dose of CM and temporal maximum intensity projection (TMIP) and to investigate its image quality compared to standard-CCTA. Materials and Methods: Participants comprised 30 patients with coronary artery disease who underwent dynamic-CCTA and standard-CCTA using 320-row CT. Dynamic-CCTA was continuously performed at mid-diastole throughout 15–25 cardiac cycles after bolus injection of CM [103 mg iodine/kg body weight (mgI/kg)]. TMIP-CCTA was reconstructed from three-phase dynamic-CCTA data, including a phase with peak enhancement of the ascending aorta. Standard-CCTA was performed using a standard CM dose (259 mgI/kg). Image quality of both TMIP-CCTA and standard-CCTA was analyzed. Results: The amount of CM used in TMIP-CCTA and standard-CCTA was 16.2±2.6 mL and 40.1±7.3 mL, respectively. The mean effective radiation dose was not significantly different between the two methods. Mean coronary attenuation was significantly lower for TMIP-CCTA than standard-CCTA [346.9±82.8 Hounsfield units (HU) vs. 455.4±75.3 HU, p<0.05]. Image noise was significantly lower for TMIP-CCTA than standard-CCTA (20.0±3.2 HU vs. 28.1± 3.6 HU, p<0.05). There were no differences in signal-to-noise ratio and visual assessment scores between the two methods. Conclusion: TMIP-CCTA can be performed using more than 50% less CM with the same image quality as standard-CCTA.
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