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      • KCI등재

        Variations of microhardness with solidification parameters and electrical resistivity with temperature for Al–Cu–Ag eutectic alloy

        U. Böyük,N. Maraşlı,E. Çadırlı,H. Kaya,K. Keşlioğlu 한국물리학회 2012 Current Applied Physics Vol.12 No.1

        AleCueAg eutectic alloy was directionally solidified upwards with different growth rates (1.83e 498.25 mm/s) at a constant temperature gradient (8.79 K/mm) and with different temperature gradients (3.99e8.79 K/mm) at a constant growth rate (8.30 mm/s) by using a Bridgman type directional solidification apparatus. The dependence of microhardness (HV) on the growth rate (V), temperature gradient (G) and microstructure parameter (l) were found to be HV ¼ k1 V0.10, HV ¼ k2 G0.13 and HV ¼ k3 l 0.22, respectively. The electrical resistivity of the AleCueAg eutectic cast alloy increases linearly with the temperature in the range of 300e780 K. The enthalpy of fusion and specific heat change during melting for same alloy were also determined to be 223.8 J/g, and 0.433 J/g K, respectively by a differential scanning calorimeter from heating curve during the transformation from eutectic solid to eutectic liquid.

      • KCI등재

        Interfacial energies of carbon tetrabromide

        U. Böyük,N. Maraşlı 한국물리학회 2009 Current Applied Physics Vol.9 No.3

        The equilibrated grain boundary groove shapes for solid carbon tetrabromide (CTB) in equilibrium with its melt were directly observed by using a horizontal temperature gradient stage. From the observed grain boundary groove shapes, Gibbs–Thomson coefficient (Γ) and solid–liquid interfacial energy (σSL) and grain boundary energy (σgb) of CTB have been determined to be (7.88 ± 0.8) × 10-8 K m, (6.91 ± 1.04) × 10-3 J m-2 and (13.43 ± 2.28) × 10-3 J m-2, respectively. The ratio of thermal conductivity of equilibrated liquid phase to solid phase for CTB has also been measured to be 0.90 at its melting temperature. The value of σSL for CTB obtained in present work was compared with the values of σSL determined in the previous works for same material and it was seen that the present result is in good agreement with previous works. The equilibrated grain boundary groove shapes for solid carbon tetrabromide (CTB) in equilibrium with its melt were directly observed by using a horizontal temperature gradient stage. From the observed grain boundary groove shapes, Gibbs–Thomson coefficient (Γ) and solid–liquid interfacial energy (σSL) and grain boundary energy (σgb) of CTB have been determined to be (7.88 ± 0.8) × 10-8 K m, (6.91 ± 1.04) × 10-3 J m-2 and (13.43 ± 2.28) × 10-3 J m-2, respectively. The ratio of thermal conductivity of equilibrated liquid phase to solid phase for CTB has also been measured to be 0.90 at its melting temperature. The value of σSL for CTB obtained in present work was compared with the values of σSL determined in the previous works for same material and it was seen that the present result is in good agreement with previous works.

      • KCI등재

        Determination of solid–liquid interfacial energy for a solid Sn in equilibrium with a Sn―Ag―Zn eutectic liquid

        S. Engin,U. Böyük,N. Maraşlı 한국물리학회 2011 Current Applied Physics Vol.11 No.4

        The equilibrated grain boundary groove shapes for a solid Sn in equilibrium with a Sn―Ag―Zn eutectic liquid were observed in a linear temperature gradient by using a Bridgman type directional solidification apparatus. The Gibbs―Thomson coefficient, solideliquid interfacial energy and grain boundary energy for a solid Sn in equilibrium with a Sn―Ag―Zn eutectic liquid were determined to be (8.21 ± 0.7) × 10^-8 Km,(116.2 ± 15.1) × 10^-3 Jm^-2 and (228.1 ± 34.2) × 10^-3 Jm^-2, respectively from observed grain boundary groove shapes. A comparison of present results with the previous experimental and theoretical results for similar solids in equilibrium with the different liquid was also made.

      • KCI등재

        The Role of Mitochondrial Dynamic Dysfunction in Age-Associated Type 2 Diabetes

        Vezza Teresa,Díaz-Pozo Pedro,Canet Francisco,de Marañón Aranzazu M.,Abad-Jiménez Zaida,García-Gargallo Celia,Roldan Ildefonso,Solá Eva,Bañuls Celia,López-Domènech Sandra,Rocha Milagros,Víctor Víctor M 대한남성과학회 2022 The World Journal of Men's Health Vol.40 No.3

        Mitochondrial dynamics, such as fusion and fission, play a critical role in maintaining cellular metabolic homeostasis. The molecular mechanisms underlying these processes include fusion proteins (Mitofusin 1 [MFN1], Mitofusin 2 [MFN2], and optic atrophy 1 [OPA1]) and fission mediators (mitochondrial fission 1 [FIS1] and dynamin-related protein 1 [DRP1]), which interact with each other to ensure mitochondrial quality control. Interestingly, defects in these proteins can lead to the loss of mitochondrial DNA (mtDNA) integrity, impairment of mitochondrial function, a severe alteration of mitochondrial morphology, and eventually cell death. Emerging evidence has revealed a causal relationship between dysregulation of mitochondria dynamics and age-associated type 2 diabetes, a metabolic disease whose rates have reached an alarming epidemic-like level with the majority of cases (59%) recorded in men aged 65 and over. In this sense, fragmentation of mitochondrial networks is often associated with defects in cellular energy production and increased apoptosis, leading, in turn, to excessive reactive oxygen species release, mitochondrial dysfunction, and metabolic alterations, which can ultimately contribute to β-cell dysfunction and insulin resistance. The present review discusses the processes of mitochondrial fusion and fission and their dysfunction in type 2 diabetes, with special attention given to the therapeutic potential of targeting mitochondrial dynamics in this complex metabolic disorder.

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