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      저자 : Mustafa Turunç, (검색결과 1 건)
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        Serum Inflammatory Biomarkers in Patients with Nonarteritic Anterior Ischemic Optic Neuropathy

        Nurullah Koç,ak,Bilge Eraydın,Mustafa Turunç,,Volkan Yeter,İ,nci Gü,ngö,r 대한안과학회 2020 Korean Journal of Ophthalmology Vol.34 No.6

        Purpose: To evaluate the neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), platelet-to-lymphocyteratio (PLR), and systemic immune-inflammation index (SII) in patients with non-arteritic anterior ischemic optic neuropathy(NAION). Methods: Fifty-six patients with NAION and 60 age-sex matched healthy controls were included in the study. Demographiccharacteristics and laboratory findings of the patients and the controls were obtained from the electronic medical records. NLR, PLR, MLR, and SII were calculated and compared between the groups. Cutoff values were also determined. Results: Neutrophil, monocyte and platelet counts were higher in the NAION group than in the control group, but the differencewas not statistically significant (p > 0.05). The mean NLR and SII were higher in the NAION group than in the controlgroup (p = 0.004 and p = 0.011, respectively). In the receiver operating characteristic curve analysis, the areas under thecurve for NLR were 0.67, and NLR >1.79 predicted NAION with a sensitivity of 71% and specificity of 59%. The areas under thecurve for SII was 0.66, and SII of >417 predicted NAION with a sensitivity of 71% and specificity of 49%. There was no significantdifference in PLR and MLR between the groups (p = 0.105 and p = 0.347, respectively). Conclusions: The current study demonstrated that NAION patients had increased NLR and SII levels compared with controlsubjects. Elevated NLR and SII might serve as readily available inflammatory predictors in NAION patients.

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