The Healing Effects of Autologous Mucosal Grafts in Experimentally Injured Rabbit Maxillary Sinuses

Murat Topdag,Ahmet Kara,Esma Konuk,Necdet Demir,Murat Ozturk,Sebla Calıskan,Deniz Ozlem Topdag,Arif Ulubil,Ibrahim Gurkan Keskin,Mete Iseri 대한이비인후과학회 2016 Clinical and Experimental Otorhinolaryngology Vol.9 No.1

Objectives. Healing processes of the nose and paranasal sinuses are quite complex, and poorly understood. In this study, we aimed to compare the effect of mucosal autologous grafts on the degenerated rabbit maxillary sinus mucosa with spontaneous wound healing. It is hypothesized that mucosal grafts will enhance ciliogenesis and improve the morphology of regenerated cilia. Methods. Ten female New Zealand rabbits were included in the study. They underwent external maxillary sinus surgery through a transcutaneous approach. A total of 20 maxillary sinuses were randomly divided into 2 groups: ‘spontaneous healing group’ and ‘autologous graft group.’ The animals were sacrificed at the 14th day after the surgery. Scanning electron microscope (SEM), and light microscope were used for the evaluation. Results. Cellular composition of the graft group is better than the spontaneous healing group. The graft group had larger areas covered with ciliary epithelium than the spontaneous healing group, and the mean length of the cilias were also longer. Additionally, there were wider cilia with abnormal morphology areas in the spontaneous healing group. Conclusion. In our opinion, covering of the denuded areas with a graft improves re-epithelization, and may prevent the early complications after sinus surgeries.

MLR & ANN approaches for prediction of compressive strength of alkali activated EAFS

Murat Ozturk,Omer F. Cansiz,Umur K. Sevim,Muzeyyen Balcikanli Bankir 사단법인 한국계산역학회 2018 Computers and Concrete, An International Journal Vol.21 No.5

In this study alkali activation of Electric Arc Furnace Slag (EAFS) is studied with a comprehensive test program. Three different silicate moduli (1-1,5-2), three different sodium concentrations (4%-6%-8%) for each silicate module, two different curing conditions (45%-98% relative humidity) for each sodium concentration, two different curing temperatures (400°C-800°C) for each relative humidity condition and two different curing time (6h-12h) for each curing temperature variables are selected and their effects on compressive strength was evaluated then regression equations using multiple linear regressions methods are fitted. And then to select the best regression models confirm with using the variables, the regression models compared between itself. An Artificial Neural Network (ANN) models that use silicate moduli, sodium concentration, relative humidity, curing temperature and curing time variables, are formed. After the investigation of these ANN models’ results, ANN and multiple linear regressions based models are compared with each other. After that, an explicit formula is developed with values of the ANN model. As a result of this study, the fluctuations of data set of the compressive strength were very well reflected using both of the methods, multiple linear regression with quadratic terms and ANN.

Antithrombotic effect of epigallocatechin gallate on the patency of arterial microvascular anastomoses

Igde, Murat,Ozturk, Mehmet Onur,Yasar, Burak,Bulam, Mehmet Hakan,Ergani, Hasan Murat,Unlu, Ramazan Erkin Korean Society of Plastic and Reconstructive Surge 2019 Archives of Plastic Surgery Vol.46 No.3

Background Microvascular anastomosis patency is adversely affected by local and systemic factors. Impaired intimal recovery and endothelial mechanisms promoting thrombus formation at the anastomotic site are common etiological factors of reduced anastomosis patency. Epigallocatechin gallate (EGCG) is a catechin derivative belonging to the flavonoid subgroup and is present in green tea (Camellia sinensis). This study investigated the effects of EGCG on the structure of vessel tips used in microvascular anastomoses and evaluated its effects on thrombus formation at an anastomotic site. Methods Thirty-six adult male Wistar albino rats were used in the study. The right femoral artery was cut and reanastomosed. The rats were divided into two groups (18 per group) and were systemically administered either EGCG or saline. Each group were then subdivided into three groups, each with six rats. Axial histological sections were taken from segments 1 cm proximal and 1 cm distal to the microvascular anastomosis site on days 5, 10, and 14. Results Thrombus formation was significantly different between the EGCG and control groups on day 5 (P=0.015) but not on days 10 or 14. The mean luminal diameter was significantly greater in the EGCG group on days 5 (P=0.002), 10 (P=0.026), and 14 (P=0.002). Intimal thickening was significantly higher on days 5 (P=0.041) and 10 (P=0.02). Conclusions EGCG showed vasodilatory effects and led to reduced early thrombus formation after microvascular repair. Similar studies on venous anastomoses and random or axial pedunculated skin flaps would also contribute valuable findings relevant to this topic.

Effects of Cigarette Smoking across Three Generations and of Perceptions of the Smoking-Cancer Relationship on the Cigarette Smoking Status of Turkish University Students

Ozturk, Candan,Bektas, Murat,Mert, Ozlem Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.11

Background: This descriptive and cross-sectional study aimed to investigate effects of cigarette smoking across three generations and perceptions of the smoking-cancer relationship on the cigarette smoking status of Turkish university students. Materials and Methods: The study sample comprised of 434 university students studying in different departments of a university. Data were collected using a socio-demographic data collection form and the Decisional Balance Scaleqand evaluated using the Mann-Whitney U test, CHAID and multiple regression analyses. Results: The average age of the students participating in the study is 19.6+.5.0, some 11.3% of the students reporting that they smoked cigarettes. No statistically significant relationship was ascertained between the cigarette smoking statuses of the students based on the cigarette smoking status of their grandparents (p=0.144). but there was alink to that of their parents (p=0.002). The difference between the cigarette smoking ratios of the students based on their perceptions of smoking-cancer relationship was statistically significant (p<0.001). Believing that there is a relationship between smoking and cancer decreased likelihood of cigarette smoking 3.7 fold. Cigarette smoking by grandparents, and believing that there is a relationship between smoking and cancer, and cigarette smoking by parents explained 8.3% of the cigarette smoking status of the students. Conclusions: While cigarette smoking by grandparents only indirectly influences cigarette smoking by the students, believing that there is a relationship between smoking and cancer, and cigarette smoking by parents are influential variables in determining cigarette smoking by Turkish students.

Effects of Perceived Parental Attitudes on Children's Views of Smoking

Ozturk, Candan,Kahraman, Seniha,Bektas, Murat Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.4

Background: The aim of this study was to examine the effects of perceived parental attitudes on children's discernment of cigarettes. Materials and Methods: The study sample consisted of 250 children attending grades 6, 7 and 8. Data were collected via a socio-demographic survey questionnaire, the Parental Attitude Scale (PAS) and the Decisional Balance Scale (DBS). Data analysis covered percentages, medians, one-way analysis of variance (ANOVA) and post-hoc tests using a statistical package. Results: There were 250 participants; 117 were male, 133 were female. The mean age was $13.1{\pm}0.98$ for the females and $13.3{\pm}0.88$ for the males. A statistically significant difference was found in the children's mean scores for 'pros' subscale on the Decisional Balance Scale (DBS) according to perceived parental attitudes (F=3.172, p=0.025). There were no statistically significant differences in the DBS 'cons' subscale scores by perceived parental attitudes. Conclusions: It was determined that while perceived parental attitudes affect children's views on advantages of smoking, they have no effect on children's views on its disadvantages.

Effects of Student Perceptions of Social Skills on their Perception of Smoking

Bektas, Murat,Ozturk, Candan,Karatas, Hulya,Bektas, Ilknur Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.14

Background: This study was conducted as a descriptive-correlational exercise with the aim of determining the effect of student perceptions of social skills on their pro and con perceptions of smoking. Materials and Methods: The study sample comprised 106 students at $6^{th}$, $7^{th}$ and $8^{th}$ grades in three primary schools. The data were collected through socio-demographic data collection form, Social Skill Perception Form and Child Decisional Balance Scale. Data were evaluated by percentage calculation, Student t test and correlation analysis. Results: While the point average of pro perception of smoking of the students with a high point average of social skill perception, was $8.6{\pm}3.1$, in those with a low social skill perception point average it was $10.7{\pm}4.2$, the difference being significant(p=0.012). The respective point averages of con perceptions were $26.8{\pm}3.7$ and $23.5{\pm}3.3$, again significant (p=0.000). While a positive medium level (r=0.410) relationship was determined between the point average of social skill perception and con perception of smoking, a negative low level (r=0.281) relationship was determined with the pro perception of smoking. Conclusions: As the social skill perception point average increases, children's con perceptions of smoking increase and their pro perceptions decrease.

Letter tothe editor : The Cumulative Colectomy Rate in Patients with Cytomegalovirus-Positive Ulcerative Colitis

( Kadir Ozturk ),( Hakan Demirci ),( Murat Kantarcioglu ),( Ahmet Uygun ),( Sait Bagci ) The Editorial Office of Gut and Liver 2015 Gut and Liver Vol.9 No.2

Analyzing the mechano-bactericidal effect of nano-patterned surfaces by finite element method and verification with artificial neural networks

Ecren Uzun Yaylaci,Murat Yaylaci,Mehmet Emin Ozdemir,Merve Terzi,Sevval Ozturk Techno-Press 2023 Advances in nano research Vol.15 No.2

The study investigated the effect of geometric structures of nano-patterned surfaces, such as peak sharpness, height, width, aspect ratio, and spacing, on mechano-bactericidal properties. Here, in silico models were developed to explain surface interactions with Escherichia coli. Numerical solutions were performed based on the finite element method and verified by the artificial neural network method. An E. coli cell adhered to the nano surface formed elastic and creep deformation models, and the cells' maximum deformation, maximum stress, and maximum strain were calculated. The results determined that the increase in peak sharpness, aspect ratio, and spacing values increased the maximum deformation, maximum stress, and maximum strain on E. coli cell. In addition, the results showed that FEM and ANN methods were in good agreement with each other. This study proved that the geometrical structures of nano-patterned surfaces have an important role in the mechano-bactericidal effect.

Effects of Self-Concept Levels and Perceived Academic Achievements of Turkish Students on Smoking Perceptions

Sert, Hilal Parlak,Bektas, Murat,Ozturk, Candan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.3

Background: The objective of this study was to examine the effect of self-concept levels and perceived academic achievements of sixth, seventh and eighth grade primary school students upon their perceptions about smoking. Method: The data were collected with the Socio-Demographic Data Collection Form, Pier-Herris Self-Concept scale and Children's Decision Balance Scale. The study sample consisted of 374 students receiving education in the sixth, seventh and eighth grades of three primary schools, which were selected among primary schools of Izmir Provincial Directorate for National Education representing three socio-economic groups with a simple random sampling method. The data were collected in December 2012-January 2013. Percentages and the t test were used in the evaluation of the data. Results: While students with a positive self-concept had score averages of $7.12{\pm}2.18$ regarding the lower dimension of smoking pros and $29.0{\pm}2.47$ regarding the lower dimension of smoking cons, their counterparts with a negative self-concept had score averages of $8.61{\pm}3.76$ (p=0.000) and $28.1{\pm}3.49$ (p=0.004), respectively. According to self-perception, there was statistical difference between perceptions of students regarding smoking (p<0.01). While students perceiving themselves successful had score averages of $7.81{\pm}3.13$ and $28.5{\pm}3.19$ regarding the lower dimension of smoking benefit and harm, students perceiving themselves unsuccessful had score averages of $8.27{\pm}3.39$ (p=0.333) and $29.01{\pm}2.05$ (p=0.235), with no difference determined. Conclusion: Students with a positive self-perception had a low perception of smoking pros and a high perception of smoking cons. Perception of academic achievement did not affect the pros and cons perceptions of children regarding smoking.

Differences of the Voice Parameters Between the Population of Different Hearing Tresholds: Findings by Using the Multi-Dimensional Voice Program

Ferit Akil,Umur Yollu,Ozcan Ozturk,Murat Yener 대한이비인후과학회 2017 Clinical and Experimental Otorhinolaryngology Vol.10 No.3

Objectives. To compare voice parameters in subjects with different hearing level. Methods. The evaluation consisted of Multi-Dimensional Voice Program (MDVP) and electroglottography. Group 1 consisted of normal hearing subjects which is bilateral average hearing better than 25 decibels (dB) whereas group 2 consisted of patients who have bilateral average hearing between the 25 and 60 dB and group 3 consisted of patients who have bilateral average hearing between the 60 and 90 dB. The evaluations were performed on males and females separately. Results. In female subjects, fundamental frequency (F0), absolute jitter, %jitter and soft phonation index (SPI) were significantly different between the group 1 and group 2. Also, we detected significant difference on maximum phonation time (MPT), fundamental frequency, absolute jitter and %jitter, and variable F0 (vF0) values between group 1 and group 3. Male subjects demonstrated significant difference between the group 1 and group 2 in MPT, absolute jitter, %jitter, vF0, and SPI parameters. Between the group 3 and group 1; differences in absolute jitter, %jitter, shimmer, %shimmer, vF0, and SPI were also significant. Conclusion. This study concluded that even mild to moderate hearing losses may affect voice patterns in adults and also females and males react differently to hearing loss in some parameters.