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      • KCI등재

        Stronger Together in Lab: Multi-Center and Laboratory Spine Studies are Closer to Publication than Single-Center and Clinical Spine Studies: Snapshot of Annual Meetings of the Spine Society of Europe

        Özcan-Ekşi Emel Ece,Canbolat Çağrı,Ayhan Selim,Ekşi Murat Şakir 대한척추외과학회 2020 Asian Spine Journal Vol.14 No.5

        Study Design: This is a cross-sectional study of literature databases.Purpose: The purpose of this study is to analyze the predictive factors for the publication rates of spine studies.Overview of Literature: Spine research has garnered worldwide interest due to the increased number of spinal disorders in aging population.Methods: We evaluated the abstracts presented at the annual meetings of the Spine Society of Europe between 2009 and 2012. Additionally, we recorded presentation categories, study designs, research types, random assignments of the subjects, single- or multi-center- based methodologies, and significance of the results.Results: We evaluated 965 abstracts, 53.5% of which were published in peer-reviewed journals. Publication rates were significantly higher for oral presentations (62.9%) and prospective studies (61.3%) as compared to the poster presentations (46.7%) and retrospective studies (44.2%), respectively (p <0.001). Clinical studies contributed to about 86.1% of the published abstracts. However, publication rates were significantly higher for laboratory studies as compared to clinical studies (70.1% vs. 50.8%, p <0.001). Multi-center studies were closer to publication than single-center studies (67.1% vs. 52.2%, p =0.009). Our study demonstrated that multi-center studies (odds ratio, 1.81; p =0.016) and laboratory studies (odds ratio, 2.60; p <0.001) are more likely to be published.Conclusions: Multi-center collaborations dedicated to experimental studies in spine research are highly ranked and more likely to be published in peer-reviewed journals.

      • KCI등재후보

        Cervical Sagittal Alignment Parameters of Patients Admitted to Neurosurgery and Emergency Clinics in a State Hospital at Eastern Part of Turkey

        Sümeyye Çoruh Kaplan,Murat Şakir Ekşi 대한척추신경외과학회 2015 Neurospine Vol.12 No.2

        Objective: Cervical spine encompasses a bridge role between the head and the lower parts of the spine and therefore has unique properties. Our aim in this study was to evaluate the cervical sagittal alignment parameters in pediatric and adult nonsurgical patients and to find any differences in respect of age, sex and admission type. Methods: All patients who were admitted to emergency and neurosurgery clinics of Diyarbakir Bismil State Hospital due to cervical spine problems (trauma, radiculopathy, paraspinal pain) in 2014 were enrolled retrospectively into the study. Cervical anteriorposterior and lateral X-rays were obtained. Our exclusion criteria were cervical coronal deformity, multitrauma, Glasgow Coma Scale <15, traumatic disruption of the cervical spine, history of malignancy, spinal infection, metabolic or rheumatologic diseases. Results: There were 44 female and 55 male patients (n=99) in the study. Thirty-five (35.35%) of the patients were younger than 18 years of age. Mean cervical spinal alignment parameters were as follows: -42.81±11.23° (OC2), -17.15±11.48° (C2-C7), -29.82±7.60° (T1 slope), -3.62±3.05° (C3), -3.14±3.05 (C4), -3.80±2.74° (C5), -3.12±2.36° (C6), -3.43±2.53° (C7). Positive correlations were observed between age-C2C7 angle, C2C7 angle-T1 slope, C3 angle-C4 angle, C4 angle-OC2 angle, C4 angle-T1 slope, C4 angle-C5 angle. The one only negative correlation was between OC2 angle-C2C7 angle. Conclusion: In this regional study, it has been observed that global cervical lordosis increases as age increases. C4 vertebra is in the middle of this evaluation as it has many correlations with other cervical segments, which should be kept in mind when making surgical plans for this delicate spine region.

      • KCI등재후보

        Concomitant Double Tumors of Myxopapillary Ependymoma Presented at Cauda Equina-Filum Terminale in Adult Patient

        Ulaş Yener,Mustafa Güdük,Murat Şakir Ekşi,Murat Hamit Aytar,Aydın Sav,Serdar Özgen 대한척추신경외과학회 2016 Neurospine Vol.13 No.1

        A 32-year-old man presented with gradually increasing bilateral buttock pain. He had intermittent claudication. Multiple, homogenously enhanced intradural extramedullary lesions at L2-L3 and L5-S1 levels were observed on magnetic resonance imaging. The tumors were debulked and were removed in piecemeal pattern until they had completely been resected. Histopathological examination of the surgical specimens confirmed that both tumors were myxopapillary ependymomas (MPE). MPE presenting as concomitant double tumor at conus-cauda-filum level are very rare. This kind of presentation could not be directly considered as dissemination, since both tumors were in the site of classical origin of MPE. Ten cases of double spinal MPEs have been reported to date. Including the present case, analysis of the 11 patients revealed some facts. There is a male predominance, which is opposite to the ependymomas that are commonly observed in females. Median age at presentation is 15 years. Most pronounced symptom is low back pain that sometimes radiates to lower extremities. Surgical approach was aimed in all tumors, which could be succeeded in all tumors except one. Adjuvant radiation therapy was applied in 5 patients. No recurrences have been reported after surgery or surgery + radiotherapy regimens.

      • KCI등재

        Relapsed Wilms’ tumor with multiple brain metastasis

        Akın Akakın,Baran Yılmaz,Murat Şakir Ekşi,Özlem Yapıcıer,Türker Kılıç 대한소아청소년과학회 2016 Clinical and Experimental Pediatrics (CEP) Vol.59 No.no.sup1

        Wilms’ tumor is the most common malignant renal tumor in childhood. The brain metastasis of a Wilms’ tumor with anaplastic histopathology is rare. We present the case of an 8-year-old girl with Wilms’ tumor, who presented with multiple brain metastases 5 years after her primary diagnosis. The brain masses were diagnosed after a generalized tonic-clonic seizure attack. The big solid mass in the cerebellum was resected, and whole-brain radiotherapy was performed, after which, she succumbed to her disease. In the case of clinical suspicion, cranial surveillance should be included in the routine clinical work-up for Wilms’ tumor. Combined aggressive therapy (surgery+radiotherapy+chemotherapy) should be applied whenever possible, for both better survival and palliative aspects.

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