Surface Treatments : IMPROVING RELIABILITY AND QUALITY OF MACHINES , INSTRUMENTS IN SUCCESSION USE BY METHODS OF THE ELECTROEROSION TREATMENT & OF REGULARIZATION OF MICROGEOMETRY OF SURFACES OF THE PARTS

Mulin Yuri Ivanovich 대한금속재료학회 ( 구 대한금속학회 ) 1995 Advanced Material and Processing Vol.1 No.-

Green and Efficient Synthesis of an Adsorbent Fiber by Plasma-induced Grafting of Glycidyl Methacrylate and Its Cd(II) Adsorption Performance

Haonan Chen,Mulin Guo,Xiaohong Yao,Zhengwei Luo,Kai Dong,Zhouyang Lian,Wuji Wei 한국섬유공학회 2018 Fibers and polymers Vol.19 No.4

A new chelating adsorbent for the removal of Cd(II) from aqueous solution, PP-g-GMA-DETA fibers, is prepared by plasma induced grafting of glycidyl methacrylate (GMA) onto the surface of polypropylene (PP) fibers, followed by modification with diethylenetriamine (DETA). The effects of grafting parameters on the grafting degree are investigated. Fourier transform infrared spectroscopy, scanning electron microscopy, and X-ray photoelectron spectroscopy prove the successful grafting of GMA onto the surfaces of PP fibers and the subsequent conversion of epoxy groups of grafted GMA to amine groups, on reaction with DETA. The adsorption performances of Cd(II) by the chelating fibers are evaluated in detail. Kinetic and isothermal parameters are also evaluated. The data fit well with the pseudo-second order and Langmuir isotherm model, respectively. The maximum adsorption capacity of Cd(II) is 46.47 mg g-1 and the prepared fibers show selective adsorbability towards target Cd(II) in presence of competing Mg(II) ions.

Study of Nursing Home’s Color Environment according to Space Function

Yerim Choi,Mulin Jeong,Heykyung Park 한국색채학회 2017 AIC 2017 Jeju Vol.2017 No.10

As the length of average life span has increased, the number of the elderly in Korea has also rapidly increased, being ranked as first among the OECD countries. According to the previous study, the Korean government has expanded the facilities for elderly nursing homes and policies for the elderly in order to deal with the rapidly aging population, and the importance of the environmental aspects in these facilities has emerged. Therefore, this study suggests a way of improvement by studying the color system in 8 elderly nursing homes in Korea using the spectrophotometer (Minolta, CM-2600d). The range of the place in the experiment is limited to residential, nursing, and common spaces. The colors of the floor, wall, and furniture are grouped into main, secondary, or accent colors depending on the ratio of area. As a result, first of all, the colors in Y group, which look bright and calm, are used most frequently. Secondly, it shows similar standards in the range of values of mid-brightness and low-saturation. Lastly, the colors in the cold color family appear rarely, requiring partial color application.

OSI-027 alleviates rapamycin insensitivity by modulation of mTORC2/AKT/TGF-β1 and mTORC1/4E-BP1 signaling in hyperoxia-induced lung injury infant rats

Long Li,Liang Mulin,Yanling Liu,Wang Pan,Dang Hongxing 대한독성 유전단백체 학회 2021 Molecular & cellular toxicology Vol.17 No.3

Background The mechanism of long time and high-concentration oxygen treatment leading to acute lung injury (ALI) or developmental lung disease in infants is currently unclear. Here we found that compared with the effect of rapamycin, pan-mTOR1/2 inhibitor OSI-027, alleviates hyperoxia-induced lung injury (HILI) by modulation of mTORC2/AKT/TGF-β1 and mTORC1/4E-BP1 signaling in infant rats. Objective Infant rats were treated with continuous inhalation of 90% medical oxygen. Normal saline, rapamycin, or OSI-027 was intraperitoneally injected, and the status of lung injury was tested on days 3, 7, and 14. The activation of mTOR/AKT/TGFβ1 and mTORC1/4E-BP1 signaling was confirmed by immunohistochemistry and Western blot analysis in normal and hyperoxia-treated live precision-cut lung tissues. The inhibitory effect of OSI-027 extended to the active state of other proteins implicated in mTOR1/2 signaling was demonstrated in hyperoxia-induced injured lung tissues. Results Our data demonstrate that hyperoxia-induced serious lung inflammation and fibrosis. OSI-027 significantly attenuated the pathological process of HILI, inhibit the phosphorylation of the primary downstream targets of mTORC1/C2, and reduce the activation of TGF-β1 signaling. Conclusions The results suggest that mTORC2/AKT/TGF-β1 and the rapamycin-insensitive mTORC1/4E-BP1 (Thr37/46) signaling has an important effect during HILI with a potential meaning for the progress of novel anti-hyperoxia-injury strategies. Background The mechanism of long time and high-concentration oxygen treatment leading to acute lung injury (ALI) or developmental lung disease in infants is currently unclear. Here we found that compared with the effect of rapamycin, pan-mTOR1/2 inhibitor OSI-027, alleviates hyperoxia-induced lung injury (HILI) by modulation of mTORC2/AKT/TGF-β1 and mTORC1/4E-BP1 signaling in infant rats. Objective Infant rats were treated with continuous inhalation of 90% medical oxygen. Normal saline, rapamycin, or OSI-027 was intraperitoneally injected, and the status of lung injury was tested on days 3, 7, and 14. The activation of mTOR/AKT/TGFβ1 and mTORC1/4E-BP1 signaling was confirmed by immunohistochemistry and Western blot analysis in normal and hyperoxia-treated live precision-cut lung tissues. The inhibitory effect of OSI-027 extended to the active state of other proteins implicated in mTOR1/2 signaling was demonstrated in hyperoxia-induced injured lung tissues. Results Our data demonstrate that hyperoxia-induced serious lung inflammation and fibrosis. OSI-027 significantly attenuated the pathological process of HILI, inhibit the phosphorylation of the primary downstream targets of mTORC1/C2, and reduce the activation of TGF-β1 signaling. Conclusions The results suggest that mTORC2/AKT/TGF-β1 and the rapamycin-insensitive mTORC1/4E-BP1 (Thr37/46) signaling has an important effect during HILI with a potential meaning for the progress of novel anti-hyperoxia-injury strategies.

Mechanical Properties and Experimental Study of a New Laminated Girder Single Tower Cable-Stayed Bridge

Xiaoli Xie,Haolin Su,Mulin Pang 한국강구조학회 2023 International Journal of Steel Structures Vol.23 No.3

With the span of steel truss girder cable-stayed bridge (STGCB) increases, it is easy to have local stability problems caused by the increase of axial forces, and the whole steel truss girder uses a large amount of steel. To solve these problems, a new laminated girder single tower cable-stayed bridge (NLGCB) is proposed in this paper. The structure of NLGCB is similar to STGCB, the difference is that the lower chords of the main girder near the cable tower are changed into the concrete structure, while the web members and upper chords are made of steel. Thus, a new type of concrete-steel laminated girder is formed, so as to improve the stress characteristics of the main girder. In order to verify the superiority of mechanical properties of NLGCB, a test bridge with an unequal span (5 m + 6 m) was constructed. The natural frequency of the first in-plane vibration of the bridge was measured by the pulsation test, and the stresses and deflections of the structure were tested by the static load test. The static and dynamic characteristics of a 300 m + 300 m span bridge were analyzed by finite element software and compared with STGCB. The results show that the natural frequency of the first in-plane vibration of the structure is close to the calculated value, and the vibration modes are consistent with the finite element simulation ones. When the steel consumption is reduced by 13.7% and the concrete consumption is not much, the strength, stiffness, natural vibration frequency, and stability of the structure are greatly improved.

Water-solid Suspension Grafting of Dual Monomers on Polypropylene to Prepare Ion-imprinted Fibers for Selective Adsorption of Cr(VI)

Zhengwei Luo,Lei Li,Mulin Guo,Hui Jiang,Wenhua Geng,Wuji Wei,Zhouyang Lian 한국섬유공학회 2020 Fibers and polymers Vol.21 No.12

In this work, a new strategy was developed to prepare Cr(VI)-imprinted polypropylene (PP) fibers-based materialsfor the adsorption of Cr(VI) from water. Granular PP was modified with dual monomers (glycidyl methacrylate (GMA) andacrylamide (AM)) by water-solid suspension grafting copolymerization. Then, this fibers morphology was obtained by meltblowing. Hence, the preparation steps of the fibrous Cr(VI)-imprinted adsorbent involved surface ion-imprinting andcrosslinking. The influence of the grafting conditions on the grafting percentage was investigated. The maxima graftingpercentages of GMA and AM were 16.4 and 10.6 %, respectively. The chemically modified products showed good mobilityand stability, thus meeting the requirements of melt-blowing method. The prepared Cr(VI)-imprinted polymers showed amaximum adsorption capacity to Cr(VI) of 43.2 mg/g at pH 3. The adsorption data were well fitted by the pseudo-secondorderand Langmuir adsorption models. The adsorbent showed good selectively toward Cr(VI) in a mixed solution containingCu(II) and SO42−. The X-ray photoelectron spectroscopy demonstrated that the adsorbed Cr(VI) was partly reduced to Cr(III).

국내 대형종합병원 색채환경 특성 분석

박혜경(Heykyung Park),오지영(Jiyoung Oh),정무린(Mulin Jeong) 한국색채학회 2016 한국색채학회 논문집 Vol.30 No.2

종합병원은 다수의 사람들이 이용하는 공공의료시설로서 이용목적에 따라 각 공간에 대한 이용자의 요구성이 다르게 나타난다. 그러므로 환경색채는 의료시설에서 다양하게 요구되어지는 공간기능을 지원할 수 있도록 적용되어야 하며, 이러한 색채의 환경지원성은 공간의 시각적 이미지를 형성함과 동시에 ‘치료’를 목적으로 하는 병원에서 보조적인 도구로서 사용될 수 있다. 본 연구는 국내 대형종합병원의 색채 환경 현황 및 특성을 파악하는 것을 목적으로 하며, 향후 종합병원의 공간기능을 지원하는 환경색채 계획의 기초자료로 활용될 수 있을 것으로 기대된다. 연구대상은 국내 1,000병상 이상의 종합병원 8곳이며, 직접 방문하여 분광측색기를 이용하여 종합병원의 환경색채를 측정하였다. 측정된 색채데이터에 근거하여 색상, 명도, 채도의 특성을 도출하였고, IRI 이미지스케일을 이용한 형용사 어휘 분석을 통하여 색채 환경 이미지 특성을 알아내었다. 연구결과는 다음과 같다. 첫번째, 종합병원 환경색채에서 가장 많이 사용되는 색상은 Y계열(Y, YR)이며, 중명도-저채도 범위에 주로 색채가 분포되어 있는 것으로 나타났다. 두 번째, 로비와 외래의 환경색채는 전반적으로 유사한 색상계열, 명도, 채도가 적용되고 있으며, 이미지스케일 어휘 또한 동일하게 나타나, 로비와 외래의 통일감있는 색채구성이 이루어지고 있음을 알 수 있었다. 그러나 공간의 기능이 다르므로 이에 따른 색채환경이 구성되어져야 할 것으로 사료된다. 세 번째, 병동에서는 ‘구역식별 및 병실안내 기능’을 지원할 수 있는 환경색채 도입이 나타났고, 비교적 최근에 건립된 병원일수록 이러한 색채사용에 적극적임을 알 수 있었다. 네 번째, 병실은 환자의 건강과 가장 밀접한 관계를 갖는 공간이므로, 병의 치유 및 정신건강에 도움이 되는 색을 검증하여 보조적인 치료도구로서 효과적으로 사용하는 것이 바람직하다고 사료된다. When it comes to general hospital, though multiple people use the hospital for public health service, the demand for its space varies based on the purpose of usage. Hence the environment color should be applied to support the function of its space depending on the need in medical facilities. Environmental affordance of color should build visual image of the space, at the same time, use as an assistive tool for the ‘treatment’ in the hospital. This study researched color environment in domestic major general hospitals in order to suggest improvement point for environment color plan of each space of general hospital. Eight general hospitals which accommodate over 1,000 sickbeds were selected for the research. Environment colors for each hospital space were directly measured by spectrophotometer. Based on the color data, this study presents the color features of each hue, value, and chroma and the image feature of color environment by analysing IRI image scale adjectives. The results of this study are as followings: First, the most frequent hue in color environment of general hospitals is Y lined(Y,YR), on the other hand, value and chroma are spread in middle value-low chroma. Second, environment color of lobby and outpatient department generally applies similar hue, value, and chroma. Because the adjectives of image scale were similar as well, it refers the color composition of lobby and outpatient department have its unity. However, lobby and outpatient department carry out different functions its space, it need to design for its purpose. Third, colors in hospital wards are able to support the function as an aisle. Recently constructed hospitals tends to be more positive to use the color. Forth, because the wards are closely related to the patient’s health, the colors which are helpful for recovery and mental health should be verified and used efficiently as an assistive treatment tool.

Methods of Improving the Natural Vibration Characteristics of the Through Tied-Arch Bridge and Test Verification

Chen Qiu,Xiaoli Xie,Chuangjie Yang,Xia Qin,Mulin Pang 한국강구조학회 2022 International Journal of Steel Structures Vol.22 No.1

A through tied-arch bridge with multi-point elastic constraints (MTAB) is proposed based on the truss structure concept to improve the natural vibration characteristics of the conventional through tied-arch bridge (CTAB). Rigid inclined rods are added between the main beam and arch ribs to form an integral truss structure with arch ribs as upper chords, rigid inclined rods as web members, and the main beam as a bottom chord to increase the rigidity of the structure. Through timely system transformation, arch ribs bear all dead loads and the integral truss structure bears all the live loads so that the advantages of arch ribs and web members are maximized. The pulsation test and fi nite element analysis (FEA) were carried out to verify the superiority of the natural vibration characteristics of the MTAB based on a 50 m span test bridge. Taking a 350 m span arch bridge as an example, the natural vibration characteristics and other mechanical characteristics of the MTAB were studied and compared with that of the CTAB. The results show the MTAB has better mechanical properties and economy, especially natural vibration characteristics and stiff ness.

Sputum Autoantibodies Are More Relevant in Autoimmune Responses in Asthma than Are Serum Autoantibodies

Rundong Qin,Fei Long,Xiaojun Xiao,Jing Xiao,Zhengyu Zheng,Mulin Feng,Renbin Huang,Tao Peng,Jing Li 대한천식알레르기학회 2019 Allergy, Asthma & Immunology Research Vol.11 No.3

Purpose: The data on the differences between sputum autoantibodies (Sp-Abs) and serum autoantibodies (Se-Abs) in reflection of autoimmune responses to lungs is still lacking. Methods: Ten types of Abs were investigated in matched Se and Sp samples collected from recruited subjects. Correlations between Ab levels and airway inflammatory parameters and measures of pulmonary function were assessed. The network-based and inter-correlated analysis was performed to explore the patterns of Sp- and Se-Ab profiles. Results: Fifty stable asthmatic patients and 24 healthy volunteers were recruited for our study, 15 with mild asthma, 18 with moderate asthma and 17 with severe asthma. The concentrations of Sp-Ab against U1 small nuclear ribonucleoprotein (Sp-anti-U1-SnRNP), Sp-Ab against Smith antigen and Se-Ab against thyroid peroxidase (anti-TPO) in severe asthmatics and Sp-anti-U1-SnRNP in moderate asthmatics were significantly higher compared to healthy controls and mild asthmatic subjects (P < 0.05). Sp-anti-U1-SnRNP levels were positively correlated with the dose of inhaled corticosteroids, Sp eosinophil counts and fractional exhaled nitric oxide (r = 0.326, P = 0.022; r = 0.356, P = 0.012; r = 0.241, P = 0.025, respectively) and negatively correlated with Sp neutrophil counts (r = −0.308, P = 0.031) with adjustment for age. Spearman's correlation matrix showed multiple inter-correlations among Sp-Abs and Se-Abs (P < 0.05) while only the levels of Ab against DNA topoisomerase and anti-TPO in Se were correlated with those Sp-Ab counterparts (P < 0.05). The network-based analysis defined 2 clusters: clusters 1 and 2 contained 10 Sp-Abs and 10 Se-Abs, respectively. Conclusions: This study observes that Sp-Abs are more associated with clinical parameters and the severity of disease in asthma compared to Se-Abs. Targeting on Sp-Abs which are the hallmark of the localized autoimmune event might help us better understand the role of autoimmunity in the pathological mechanism of asthma. Keywords: Asthma; autoimmunity; autoantibodies; sputum; se