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        Evaluating the importance of different computed tomography scan-based factors in predicting the outcome of extracorporeal shock wave lithotripsy for renal stones

        Muhammad Waqas,Imad-ud-din Saqib,Muhammad Imran Jamil,Mohammad Ayaz Khan,Saeed Akhter 대한비뇨의학회 2018 Investigative and Clinical Urology Vol.59 No.1

        Purpose: To evaluate the impact of various computed tomography scan-based parameters of renal stones on the outcome of extracorporeal shock wave lithotripsy (ESWL). Materials and Methods: We conducted a retrospective study of patients who underwent ESWL for renal stones (sized 5–20 mm) from January 2013 to December 2016. We evaluated body mass index, location of the stone, skin-to-stone distance (SSD), stone attenuation value (SAV), stone diameter, Hounsfield density, stone area, and stone volume. Statistical analysis was done and significance was confirmed by multivariate logistic regression analysis. Results: Of the 203 patients 122 (60.1%) had successful clearance of the stone. The presence of a double J stenting, a lower pole location, a higher SAV, higher Hounsfield density, larger stone area, larger stone diameter, and higher stone volume were negative predictors of ESWL outcome. When these parameters were analyzed with multivariate logistic regression analysis, stone location, SSD, and SAV were the only significant independent predictors of the outcome of ESWL. Conclusions: Stone location, SSD, and SAV are reliable and strong predictors of ESWL outcome for the treatment of renal stones.

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        First-Principles Description of the Different Phases in the Li$_{2}$NH Compound: Electronic Structure and Optical Properties

        Madiha Makhdoom,Muhammad Imran Jamil,Sikander Azam,Muhammad Irfan,Zeesham Abbas,Banat Gul,Saleem Ayaz Khan,Xiaotian Wang 한국물리학회 2019 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.74 No.12

        A hydrogen storage material can also be used as a potential and effective solid reducing agent in addition to its applications as an important energy carrier. The density function theory has been used to find the structural and optoelectronic properties of the Li$_{2}$NH compound. The exchange-correlation functional based GGA (generalized gradient approximation) is applied for calculating structural and optoelectronic properties. The expression for the formation is used to identify the stability, which is further confirmed by calculating the structural properties of Li$_{2}$NH. The calculations of the band structure show that a direct band gap is present between the occupied Li and N orbitals. A deep analysis of the optical properties was performed under incident photon radiation at energies up to 14 eV. Our calculated refractive index $n$(0) and the static part of the dielectric constant $\varepsilon_{2}$(0) are analogous to the experimental and other reported theoretical value.

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        Mechanisms of Cr(VI) resistance by endophytic <i>Sphingomonas</i> sp. LK11 and its Cr(VI) phytotoxic mitigating effects in soybean (<i>Glycine max</i> L.)

        Bilal, Saqib,Khan, Abdul Latif,Shahzad, Raheem,Kim, Yoon-Ha,Imran, Muhammad,Khan, Muhammad Jamil,Al-Harrasi, Ahmed,Kim, Tae Han,Lee, In-Jung Elsevier 2018 Ecotoxicology and environmental safety Vol.164 No.-

        <P><B>Abstract</B></P> <P>Chromium Cr(VI) is highly toxic and leads to impaired phenotypic plasticity of economically important crops. The current study assessed an endophytic-bacteria assisted metal bio-remediation strategy to understand stress-alleviating mechanisms in <I>Glycine max</I> L (soybean) plants inoculated with <I>Sphingomonas</I> sp. LK11 under severe Cr(VI) toxicity. The screening analysis showed that high Cr concentrations (5.0 mM) slightly suppressed LK11 growth and metal uptake by LK11 cells, while significantly enhancing indole-3-acetic acid (IAA) production. Endophytic LK11 significantly upregulated its antioxidant system compared to control by enhancing reduced glutathione (GSH), catalase (CAT), peroxidase (POD), and superoxide dismutase (SOD) activities to counteract Cr-induced oxidative stress. Cr toxicity induced cell morphological alteration, as shown by SEM-EDX analysis and triggered significant lipid peroxidation. The interaction between LK11 and soybean in Cr-contaminated soil significantly increased plant growth attributes and down-regulated the synthesis of endogenous defense-related phytohormones, salicylic acid and abscisic acid, by 20% and 37%, respectively, and reduced Cr translocation to the roots, shoot, and leaves. Additionally, Cr-induced oxidative stress was significantly reduced in LK11-inoculated soybean, regulating metal responsive reduced GSH and enzymatic antioxidant CAT. Current findings indicate that LK11 may be a suitable candidate for the bioremediation of Cr-contaminated soil and stimulation of host physiological homeostasis.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Endophytic LK11 act as an alternative strategy for alleviating chromium stress from soybean. </LI> <LI> IAA producing capability of LK11 was remarkably upregulated Under chromium stress. </LI> <LI> LK11 assoiciation promoted host plant growth attributes and modulated endogenous hormones and antioxidants. </LI> <LI> LK11 Inoculated soybean displayed reduced accumulation of chromium. </LI> </UL> </P>

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