위암 환자에서 위절제술후 나타나는 담도확장의 임상적 의의: 추적 CT 소견을 중심으로

윤구섭,백승연,이문규,김영환,오용호 울산대학교 의과대학 1993 울산의대학술지 Vol.2 No.1

A retrospective review of consecutive 35 patients'pre and post operative abdominal computed tomography was performed to determine frequency and degree of bile duct dilatation following Billroth Ⅱ operation for stomach cancer and it's clinical significance. Degree of intrahepatic biliary dilatation was classified as mild, moderate, marked according to the extension into central, middle and peripheral zone of liver, respectively. Three specialists on the abdominal image participated in analysis of those findings without prior information of the patients. Intrahepatic biliary dilatation was seen in 22 patients(63%) analysed by at least one radiologist, in 13 patients(37%) by at least two radiologists. Bile duct dilatation on CT was common finding and not necessarily meant tumor recurrence. Vagotomy and afferent loop resulted form Billroth Ⅱ were one of possible causes of bile duct dilatation. This study showed in the cases of bile duct dilatation without clinical and other radiological evidence of recurrence, no further study are needed and only enough to follow up study.

바이모달 저상굴절차량의 자동운전시스템을 위한 시뮬레이터 구현

류제(Ryu Je),황병일(Hwang Byoung-Il),이상남(Lee Sang-Nam),류희문(Ryu Hee-Moon),변윤섭(Byun Yeun-Sub) 한국철도학회 2009 한국철도학회 학술발표대회논문집 Vol.2009 No.5월

This paper discusses about the implementation of a simulator for the Navigation Control System(NCS) of bimodal tram. To operate a NCS of bimodal tram, values of all sorts of sensors installed in bimodal tram should be transmitted to the NCS, and the NCS calculates the measured sensor values to determine traveling direction, traveling speed, current position etc. The implementation of the simulator consists of a device applying driver’s input transaction function & virtual sensor program and a sub-rack device that controls communication with the NCS to evaluate navigation control function. The virtual sensor program can create routes (map), traveling profiles & seat information et cetera in order to transmit to the NCS, analyzes driver's input values and NCS output values to create virtual sensor values. The sub-rack device takes charge of communication with the NCS using CAN-OPEN, CAN-J1939, MVP protocols. This paper discusses about the implementation of the simulator and afterwards analyzes and evaluates the NCS simulation results.

Investigation of Microscopic Crystal Field in Co-Doped Lithium-Iron Phosphate

Seung Je Moon,Taejoon Kouh,Choong Sub Lee,Chul Sung Kim IEEE 2009 IEEE transactions on magnetics Vol.45 No.6

<P>We present the study on the structural and the magnetic properties of LiFePO<SUB>4</SUB> and LiFe<SUB>0.8</SUB>Co<SUB>0.2</SUB>PO<SUB>4</SUB>. The crystal structure was determined to be orthorhombic with space group <I>P</I>nma by Rietveld refinement method. We have observed the increase in the lattice constants with Co<SUP>2+</SUP> ion substituted. The Mossbauer spectra of olivine LiFePO<SUB>4</SUB> and LiFe<SUB>0.8</SUB>Co<SUB>0.2</SUB>PO<SUB>4</SUB> have shown distorted line broadening below <I>T</I> <SUB>N</SUB> . In order to explain the observed line broadening, we have analyzed the Mossbauer spectra by considering the full Hamiltonian for the <SUP>57</SUP>Fe nucleus, and both the magnetic dipole and the electric quadrupole interactions. Also, we have observed the anomalous change in the electric quadrupole splitting near the <I>T</I> <SUB>N</SUB>.</P>

Effect of acidity on the performance of a Ni-based catalyst for hydrogen production through propane steam reforming: K-AlSi_<i>x</i>O_<i>y</i> support with different Si/Al ratios

Do, Jeong Yeon,Kwak, Byeong Sub,Park, No-Kuk,Lee, Tae Jin,Lee, Sang Tae,Jo, Seung Won,Cha, Moon Soon,Jeon, Min-Kyu,Kang, Misook Pergamon Press 2017 International journal of hydrogen energy Vol.42 No.36

<P><B>Abstract</B></P> <P>Propane steam reforming (PSR) for the production of H<SUB>2</SUB> was catalyzed by a NiO/K-AlSi<SUB> <I>x</I> </SUB>O<SUB> <I>y</I> </SUB> catalyst synthesized with various Si/Al ratios (Si/Al = 0, 0.3, 0.5, 0.7, and 1.0). The effect of the Si/Al ratio on the acidity of the NiO/K-AlSi<SUB> <I>x</I> </SUB>O<SUB> <I>y</I> </SUB> catalyst for PSR was investigated. NiO/K-AlSi<SUB> <I>x</I> </SUB>O<SUB> <I>y</I> </SUB> gave a higher H<SUB>2</SUB> selectivity and stability during PSR than NiO/K-SiO<SUB>2</SUB> and NiO/K-Al<SUB>2</SUB>O<SUB>3</SUB>. The NH<SUB>3</SUB>-TPD results showed that the acid quantity and strength of NiO/K-AlSi<SUB> <I>x</I> </SUB>O<SUB> <I>y</I> </SUB> changed significantly depending on the Si/Al ratio. With an increased Si/Al ratio, the densities of both weak and strong acid sites increased. The C<SUB>3</SUB>H<SUB>8</SUB>- and CO-TPD results indicated that desorption amounts increased significantly in all NiO/K-AlSi<SUB> <I>x</I> </SUB>O<SUB> <I>y</I> </SUB> catalysts relative to those of NiO/K-SiO<SUB>2</SUB> and NiO/K-Al<SUB>2</SUB>O<SUB>3</SUB>, and the adsorption amount increased with the Si/Al ratio. PSR results showed that the NiO/K-AlSi<SUB> <I>x</I> </SUB>O<SUB> <I>y</I> </SUB> catalyst exhibited much better stability than the NiO/K-SiO<SUB>2</SUB> and NiO/K-Al<SUB>2</SUB>O<SUB>3</SUB> catalysts. This study confirms the following facts: when the acidity is appropriately adjusted for the catalyst, adsorption of the reaction gas increases, which eventually increases the reaction rate and also inhibits strong sintering between the nickel and the Al<SUB>2</SUB>O<SUB>3</SUB> support. As a result, deterioration of the catalyst can be reduced.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The NiO/K-AlSi<SUB> <I>x</I> </SUB>O<SUB> <I>y</I> </SUB> catalyst was synthesized for the production of H<SUB>2</SUB> from PRS. </LI> <LI> The acid quantity and strength of NiO/K-AlSi<SUB> <I>x</I> </SUB>O<SUB> <I>y</I> </SUB> changed significantly depending on the Si/Al ratio. </LI> <LI> The adsorptions of C<SUB>3</SUB>H<SUB>8</SUB> and CO increased with the Si/Al ratio. </LI> <LI> The NiO/K-AlSi<SUB> <I>x</I> </SUB>O<SUB> <I>y</I> </SUB> catalyst exhibited much better stability during PSR. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Usefulness of ROX Index and SpO₂/FiO₂ Ratio for Predicting High-flow Nasal Cannula Failure in Hypoxemic COVID-19 Patients

( Jin Hyoung Kim ),( Ae-rin Baek ),( Song-i Lee ),( Won-young Kim ),( Yong Sub Na ),( Bo Young Lee ),( Gil Myeong Seong ),( Moon Seong Baek ) 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.0

Background ROX index after high-flow nasal cannula (HFNC) initiation can be helpful to identify low-risk patients of HFNC failure in patients with acute hypoxemic respiratory failure. However, it remains unknown which variables are useful for predicting HFNC failure in coronavirus disease 2019 (COVID-19) receiving HFNC. This study aims to determine the discrimination ability of the ROX index and SpO2/FiO2 ratio in COVID-19 patients after HFNC initiation. Methods This multicenter study was conducted at seven university-affiliated hospitals in Korea. We retrospectively reviewed the hospitalized patients diagnosed with COVID-19 between February 10, 2020 and February 28, 2021. The ROX index and SpO2/ FiO2 ratio were calculated at 1 hour and 4 hours after HFNC initiation. The primary outcome was HFNC failure, defined as the subsequent use of mechanical ventilation despite using HFNC. Discrimination of prediction for HFNC failure was evaluated by receiver operating characteristic (ROC) curve analysis. Results During the study period, 1,565 patients with COVID-19 were hospitalized and eligible 133 patients who received HFNC were analyzed. Among them, 63 (47.4%) were successfully weaned from HFNC, and 70 (52.6%) were intubated. SpO2/FiO2 ratio at 1 hour after HFNC initiation was a more accurate predictor of HFNC failure compared to ROX index (AUC 0.762; 95% CI: 0.679- 0.846 vs. 0.733; 95% CI: 0.640-0.826) (Figure 1). In the multivariable analysis, patients older than 70 years old had 3.4 times of HFNC failure compared to younger patients (AUC 3.367 [95% CI: 1.358-8.349], p=0.009), and SpO2/FiO2 at 1 hour (AUC 0.983 [95% CI: 0.972-0.994], p=0.003) were associated with HFNC failure. Conclusions SpO2/FiO2 ratio at 1 hour after HFNC initiation demonstrated a useful predictive ability for HFNC failure. SpO2/FiO2 could be a bedside tool to identify the need for mechanical ventilation in COVID-19 patients receiving HFNC.

Downsizing gas sensors based on semiconducting metal oxide: Effects of electrodes on gas sensing properties

Song, Young Geun,Shim, Young-Seok,Kim, Sangtae,Han, Soo Deok,Moon, Hi Gyu,Noh, Myoung Sub,Lee, Kwangjae,Lee, Hae Ryong,Kim, Jin-Sang,Ju, Byeong-Kwon,Kang, Chong-Yun Elsevier Sequoia 2017 Sensors and actuators. B Chemical Vol.248 No.-

<P><B>Abstract</B></P> <P>We report the highly sensitive and selective downsized gas sensors for the IoT application. Sensing areas of Pt-interdigitated electrodes (IDEs) were varied to investigate the relation between sensing materials and electrodes. In<SUB>2</SUB>O<SUB>3</SUB> nanocolumns were deposited on the pre-patterned Pt IDEs using glancing angle deposition (GLAD). The effect of the interface resistance between electrodes and sensing materials, and the intergrain resistance between nanocolumns is analyzed by linear regression at different sensing area and incident angle of GLAD. In<SUB>2</SUB>O<SUB>3</SUB> (angle: 85°, sensing area: 0.3mm×0.3mm) nanocolumns with double Schottky barriers show the highest response and selectivity with fast response time of 10s to VOCs among the samples fabricated in this study. The analysis reveals that the intrinsic response of In<SUB>2</SUB>O<SUB>3</SUB> (angle: 85°, sensing area: 0.3mm×0.3mm) nanocolumns are dominantly affected by intergrain resistance, resulting in a high response. Our demonstration for the fundamental aspect of downsizing gas sensor makes an important contribution to the chemical sensor field with broad interest.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The sensing areas are varied to investigate the relation between sensing materials and electrodes. </LI> <LI> The effect of the interface resistance and the intergrain resistance are analyzed by linear regression. </LI> <LI> The performance of the downsizing gas sensor is greatly influenced by the interface resistance. </LI> </UL> </P>

The Preliminary Analysis of Introducing 500 km/h High-Speed Rail in Korea

Lee, Kwang-Sub,Eom, Jin Ki,Lee, Jun,Moon, Dae Seop The Korean Society for Railway 2013 International Journal of Railway Vol.6 No.1

Following the success of the KTX (Korea's first high-speed rail system) with a maximum operating speed of 300 km/h opened in 2004, experts in Korea started a research on the development of key technologies for high-speed rail (HSR) with a top speed of 500 km/h. This paper is a preliminary analysis of the research. It first reviews HSR experiences around the world, in terms of traffic and economic impacts of HSR, and presents a preliminary analysis of 500 km/h HSR in Korea. It is estimated that introduction of 500 km/h HSR with a 54% of travel time reduction will increase HSR passengers to about 9.8 million (about 78% of market share) between Seoul and Busan. It is a 23% of growth compared to the base scenario. Along with conventional rail passengers, air passengers are expected to be significantly impacted by the 500 km/h HSR. As a function of HSR travel time, the estimated market shares of both KTX and 500 km/h HSR compared to air are very comparable with previous international experiences. Based on the forecasted traffic, estimated total benefits are $758 million per year.

Anti-oxidative and Photo-protective Effects of Coumarins Isolated from Fraxinus chinensis

Lee, Bum-Chun,Lee, So-Yong,Lee, Hwa-Jeong,Sim, Gwan-Sub,Kim, Jin-Hui,Kim, Jin-Hwa,Cho, Young-Ho,Lee, Dong-Hwan,Pyo, Hyeong-Bae,Choe, Tae-Boo,Moon, Dong-Cheul,Yun, Yeo-Pyo,Hong, Jin-Tae 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.10

Free radicals and reactive oxygen species (ROS), which are generated by UV irradiation, may cause serious injury to skin cell membranes, DNA and functional proteins. In addition, these agents stimulate the expressions of matrix metalloproteinases (MMPs), which can degrade most components of the extracellular matrix (ECM), including collagen. In order to develop new anti-photoaging agents, five major components from the extract of Fraxinus chinensis extract (FCE) were identified. Two of the major components of FCE were found to be esculin (11.2%) and esculetin (1.9%). FCE ($IC_{50}:\;50.0{\mu}g/mL$ 1, 1-diphenyl-2-picrylhydrazyl (DPPH); $19.8{\mu}g/mL$, superoxide anion radical) and esculetin ($IC_{50}:\;2.1{\mu}g/mL$ DPPH; $0.6{\mu}g/mL$, superoxide anion radical) showed strong antioxidative activities. Of the compounds tested, esculetin showed the strongest scavenging activity against DPPH radicals, followed by superoxide anions from the xanthine/xanthine oxidase system. The intracellular ROS scavenging activity showed that oxidation of 5-(6-)-chloromethyl-2', 7'-dichlorodihydrofluorescein diacetate ($CM-H_2DCFDA$) was effectively inhibited by esculetin, with potent free radical scavenging activity was also shown in UVB-irradiated human dermal fibroblasts (HDFs). Moreover, treatment of UVA-irradiated HDFs with esculetin resulted in dose-dependent decreases in the expression levels of MMP-1 mRNA and protein. From these results, FCE and one of its components, esculetin, were predicted to be potentially useful as ingredients in cosmetics for protecting against photoaging.

Cavernous Hemangioma of the Abducens Nerve: Clinical Implication of Duplicated Variants: Case Report

Moon, Kyung-Sub,Jung, Shin,Lee, Kyung-Hwa,Lee, Min-Cheol Oxford University Press 2011 Neurosurgery Vol.69 No.3

<B>Abstract</B><B>BACKGROUND AND IMPORTANCE:</B><P>A cavernous hemangioma arising from the abducens nerve has not been previously reported in the literature. Based on the surgical experience with this case, the authors discuss the clinical importance and resectability potential of a duplicated abducens nerve.</P><B>CLINICAL PRESENTATION:</B><P>A 54-year-old woman presented with a recurrence of diplopia that had occurred 3 years before this admission and had spontaneously resolved without any specific treatment. On admission, there were no specific neurological deficits. Magnetic resonance imaging revealed a cone-shaped mass on the right anterior cerebellopontine angle with hemorrhagic change. Surgical resection via a standard right lateral suboccipital approach was performed. A cystic mass was found emerging from the entry zone of the Dorello canal and encircling the larger branch of the duplicate abducens nerve. Because there was no demarcation between the mass and origin branch, both were removed en bloc. Pathology revealed the presence of a cavernous hemangioma mixed with nerve tissue. Despite preserving a small branch of the duplicate abducens nerve, the patient had permanent right abducens palsy.</P><B>CONCLUSION:</B><P>A cavernous hemangioma arising from the abducens nerve should be suspected as a possible diagnosis for a cystic mass on the anterior cerebellopontine angle. Although duplication of the abducens nerve has not been clearly confirmed on clinical grounds, sacrificing the larger branch during surgery may lead to permanent abducens palsy, as in our case.</P>

Interaction of Ruthenium(II)[(1,10-phenanthroline)₂benzodipyrido[3,2-a:2',3'-c]-phenazine]²⁺ with Single Stranded Poly(dA) and Poly(dT): Turning off the Light Switch

Lee, Jeong-Mi,Choi, Ji-Yoon,Kim, Jong-Moon,Lee, Sang-Yong,Lee, Hyo-Sun,Kim, Seog-K.,Cho, Tae-Sub Korean Chemical Society 2007 Bulletin of the Korean Chemical Society Vol.28 No.6

The spectral properties, namely the circular dichroism, electric absorption and luminescence properties, of Λ- and Δ-[Ru(II)(1,10-phenanthroline)2benzodipyrido[b:3,2-h:2',3'-j]phenazine]2+ ([Ru(phen)2BDPPZ]2+) in the presence and absence of single stranded poly(dA) and poly(dT) were compared in this work. In the presence of single stranded DNAs, hypochromism in the absorption spectrum and significant changes in the circular dichroism spectrum in the ligand absorption band were apparent, indicating the strong interaction of the [Ru(phen)2BDPPZ]2+ complex with the single stranded DNAs. The luminescence intensity of the Ru(II) complex decreased stoichiometrically with increasing concentrations of the single stranded DNAs. All of these spectral changes were independent of the configuration of the Ru(II) complex and the nature of the DNA bases. Therefore, it is conceivable that both enantiomers of the [Ru(phen)2BDPPZ]2+ complex interact electrostatically with the negatively charged phosphate groups of DNA. However, the spectral properties of [Ru(II)(1,10-phenanthroline)3]2+ were not altered even in the presence of single stranded DNAs. Therefore, the size of the ligand involved in the interaction of the metal complex with the phosphate group of DNA may play an important role, even when the nature of the interaction is electrostatic.