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      • KCI등재후보
      • 포리에치렌 튜브 培養法에 依한 韓牛의 腸內線蟲類의 調査

        文武洪,박응복 진주농과대학 1968 진주농과대학 연구논문집 Vol.- No.7

        西部 慶南 一圓의 韓牛 225頭에 對한 포리에치렌 튜브를 使用한 蟲卵培養檢査에서 다음과 같은 結果를 얻었다. 1) 本 培養法은 他法보다 器具 操作이 簡便하고 糞便內 蟲卵數가 적거나 잘 發見되지않을 경우에도 多數 仔蟲이 出現하여 그 檢出率이 良好하였다. 2) 西部慶南 一圓의 韓牛腸內에 寄生하고 있는 線蟲類는 Ostertagia ostertagi, Oesophagostomum radiatum, Trichostrongylus axei, Strongyloides papillosus, Bunostomum phlebotomum의 5種으로 確認되었다. 3) 그 感染率은 Ostertagia ostertagi제일 높았고(63%), Oesophagostomum radiatum(32%), Trichostrongylus axei(28%), Strongyloides papillosus(12%)의 順이고 Bunostomum phlebotomu은 稀少하였다. An epidemiologic survey on the parasitic round worms of 225 Korean native cattles by polyethylene-tube culture of fecal samples in the western province of Kyung-Sang Nam-Do, was attempted to help prevention and treatment of the parasitic diseases. The results obtained are summarized as follows: 1) It was approved that the culture method of polyethylene-tube was more accurate and simpler in the facilities than the other culture methods. 2) Five species of parasitic round worms were found from examined cattles and infection rates of each worm were as follows; a) Ostertagia ostertagi ‥‥‥‥‥‥‥‥‥‥‥‥ 63% b) Oesophagostomum radiatum ‥‥‥‥‥‥‥‥‥‥ 32% c) Trichostrongylus axei ‥‥‥‥‥‥‥‥‥‥‥ 28% d) Strongyloides papillosus ‥‥‥‥‥‥‥‥‥‥ 12% e) Bunostomum phlebotomum was observed in very few cases.

      • 豚코레라에서의 年齡的으로 본 肋軟骨端의 病理組織學的 變化에 對하여

        文武洪 진주농과대학 1967 진주농과대학 연구논문집 Vol.- No.6

        The histopathological studies on the changes of the costo-chondral junction in 17 pigs naturally infected with S. C. V., in 7 pigs artificially inoculated, and in 30 normal pigs were conducted to help diagnosis for hog cholera. The results obtained are summarized as follows: 1. In almost every case of 3-6 monthes pigs in subacute and chronic case, zone of mature cartilage cells of costo-chondral junction were remarkably enlarged. The number of mature cartilage cells was gradually decreased in 7-13 monthes, on the other hand, in 14-16 monthes pigs, there were no apparent changes in costo-chondral junction. 2. The proliferation of mature cartilage cell was roughly proportioned to a severity of the lesions in primary bone marrow.

      • KCI등재후보
      • KCI등재
      • 한국산 돼지의 屠畜檢査例에 의한 臟器 病變調査 : Ⅱ.肝의 病變 Ⅱ.About Lesions of the Liver

        박응복,文武洪,朴琦緖,宋政根 진주농과대학 1971 진주농과대학 연구논문집 Vol.- No.10

        The organs of 400 cases which had been collected at the slaughter houses in Pusan, Masan and Chungmu cities were examined histopathologically to clear out the patterns of pathological changes of pigs kept in Korea. The report about the lesions of the liver succeeding the former report about the lung was summairzed as follows: 1) The most frequent and dominated lesions in the liver were those of hepatic ascariasis(11%) and toxic changes(35%) such as cloudy swelling, hepatic lipidosis, parenchymatous necrosis and liver cirrhosis. 2) The lesions of the liver cirrhosis observed here would be classified as three types; portal cirrhosis subdivided into secondary cirrhosis and Laennec's type. intralobular cirrhosis and biliary cirrhosis.

      • 南江銀魚에서의 橫川吸蟲의 被襄幼蟲 感染率 調査

        愼鍾旭,文武洪,朴琦緖 慶尙大學校 1976 論文集 Vol.15 No.-

        An investigation on incidence of the metacercaria of Metagonimus yokogawai in a total of 576 sweetfishes, Plecoglossus altivelis originated from the Nam River was carried out. The results obtained are sumarized as follows: 1. The infection rate of the metacercaria of Metagonimus yokogawqi in the inspected fishes was 100 percent and the average number of the metacercaria in each fish was estimated as 57 with the range of 6 to 217. 2. The distribution of metacercaria in the four divided parts fo fish was varied by the different parts. The incidences of the metacercaria in the muscle and subcutaneous tissues, in the fins, in the head and in the scales were 64.5 percent, 26.7 percent, 6.7 percent and 2.1 percent respectively. 3. The number of the metacercaria in each fish was increased according to the increase of body weight of fish. 4. The number of the metacercaria in each fish generally increased in the course of the inspection from July to October.

      • 한국산 돼지의 屠畜檢査例에 의한 臟器 病燮調査 : Ⅰ. 肺의 病燮 Ⅰ. About Lesions of the Lungs

        朴琦緖,朴應鰒,文武洪,宋政根 진주농과대학 1970 진주농과대학 연구논문집 Vol.- No.9

        The lungs of 400 cases which had been collected at the slaughter houses in Pusan, Masan and Chungmu cities were examined histopathologically to clear out the patterns of pathological changes of pigs held in Korea. 1. The most frequent and dominated lesions in the lungs were swine enzootic pneumonia (14%) and lung worm pneumonia(12%). 2. The pneumonic lesions caused by lung worms showing the bronchiolar muscle hypertrophy, eosinophilic infiltration, more limited peribronchiolar lymphocytic cuffing compared with that of swine enzootic pneumonia differentiated each other two diseases histologically. 3. The hyperemia, pulmonary ecema, interstitial pneumonia, and bronchitis occurred also frequently in the lungs, but the occurrences of the broncho pneumonia, abscess, gangrenous or granulomatous lesions were rare.

      • 간 세포암에서 VEGF, TGF-β1, b-FGF 발현의 의의

        김성용,남충현,주종우,채만규,백무준,이문수,김형철,안현철,김홍수,김창진,김창호 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

        Purpose: Angiogenesis is important for the proliferation and the metastasis of solid tumors. The growth of a solid tumor is widely recognized to depend on the process of neovascularrozation. Without angiogenesis, tumors cease to grow beyond even a few milimeters in diameter. It has been shown that tumor vascular density is an independent prognostic marker in several types of human tumors and is known to correlate with poor prognosis. To date, many angiogenic factors have been identified, such as transforming growth factor-α(TGF-α), transforming growth factor-β(TGF-β), fibroblast growth factor family(FGF), vascular endothelial growth factor(VEGF), platelet derived endothelial cell growth factor(PD-ECGF), tumor necrosis factor-α(TNF-α), and angiogenin. Hepatocellular carcinoma(HCC) is the second most common tumor in Korean males and is known as a typical hypervascular tumor with frequent portal vein invastion. The authors identified the expreesion of VEGF, TGF-β1, and b-FGF in HCC specimens and evaluated the relationship between these growth factors and the clinicopathologic characteristics of HCC. Method: We reviewed the medical records of 30 patients who were diagnosed as hepatocellular carinoma treated with hepatic resection between January 1994 and December 1998 in Soonchunhyang University Chunan Hospital. The selection of the cases was decided according to the condition of paraffin block fixation. The prognostic factors such as age, sex, tumor size, concentration of serum α-fetoprotein, presence of liver cirrhosis, presence of tumor emboli in portal vein, TMN stage, amount of transfusion during the operation, hepatitis B virus(HBV) infection, and Edmonson-Steiner(E-S) grade were investigated. Relationship between the prognostic factors and the immunopathologic expression of the TGF-β1, b-FGF, and VEGF was examined. Result: Thirty patients (24 males, 6 females) were included in the current study. The patient's mean age was 50.6 years and the age ranged from 36 to 65 years. The mean size of the tumor was found to be 5.2cm. All the patients were follewed up for 7 to 63 months. Child's classification A patients were 23(76.7%)cases, B patients were 7(23.3%)cases, and C was none. Immunohistochemical staining of HCC tumor mass in VEGF expression patients were 17(56.7%), b-FGF expression patients were 10(33.3%), and TGF-β1 expression patients were 10(33.3%). VEGF expression or more than one positive expression among the three factors correlated with tumor size and the stage of HCC but did not correlated with other clinicopathological characteristics. TGF-β1 and b-FGF did not correlate with any clinicopathological characteristics. Conclusion: The results suggest that the expression of VEGF or more than one positive expression among the three factors in HCC cells may be a significant prognostic factor of HCC.

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