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- 저자 : Miyayama, Masaru (검색결과 14 건)
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Miyayama Shiro,Yamashiro Masashi,Ikeda Rie,Yokka Akira,Komiya Hideaki,Sakuragawa Naoko 소화기인터벤션의학회 2023 International journal of gastrointestinal interven Vol.12 No.2
Background: To evaluate the outcomes of conventional transarterial chemoembolization (TACE) using guidance software for hepatocellular carci-noma (HCC) in the caudate lobe.Methods: Seventy-two patients with 79 treatment-naïve caudate lobe HCCs were eligible. TACE was performed through feeders not only identified by automated tumor-feeder detection (AFD) functionality but also detected manually. Technical success of TACE was classified into three grades accord-ing to 1-week computed tomography findings: entire tumor embolized with a safety margin (5 mm for tumors < 25 mm and 10 mm for tumors ≥ 25 mm) (grade A); tumor embolized without a margin in parts (grade B); and entire tumor not embolized (grade C). Tumor response was evaluated using the modified Response Evaluation Criteria in Solid Tumors. Tumor-feeder detectability by AFD, technical success of TACE, complete response (CR) at 2–4 months, durable CR, and local tumor progression (LTP) rates calculated by the Kaplan-Meier method were compared in each tumor among three subsegments: the Spiegel lobe (SP); paracaval portion (PC); and caudate process (CP). LTP rates between the grade A and B tumors were also com-pared.Results: The mean tumor diameter was 18.6 ± 9.9 mm (range, 6–53 mm), and 111 of 129 (86.0%) tumor feeders were detected by AFD. The rates of feeder detectability by AFD, grade A technical success of TACE, CR at 2–4 months, and durable CR in 30 SP, 38 PC, and 11 CP tumors were 71.4%, 93.3%, 93.1%, and 79.3%; 94.8%, 65.8%, 59.4%, and 34.4%; and 76.5%, 63.6%, 80.0%, and 30.0%, respectively. LTP rates of SP tumors were sig-nificantly lower than those of PC tumors (P = 0.0044), and the grade B tumors progressed more frequently (P = 0.0012).Conclusion: AFD could detect 86.0% of tumor feeders in the caudate lobe; however, the feeder detectability, technical success of TACE, and outcomes differed among the three subsegments.
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Shiro Miyayama,Masashi Yamashiro,Rie Ikeda,Junichi Matsumoto,Nobuhiko Ogawa,Kazuo Notsumata 소화기인터벤션의학회 2022 Gastrointestinal Intervention Vol.11 No.1
Background: Bleeding from duodenal varices is a rare but life-threatening complication of portal hypertension. The treatment of duodenal varices remains difficult and a definitive treatment strategy has not been established. The aim of this study was to report the technical aspects and outcomes of balloon-occluded retrograde transvenous obliteration (BRTO) using 5% ethanolamine oleate with iopamidol (EOI) for duodenal varices. Methods: Six consecutive patients with duodenal varices treated using BRTO were eligible. Endoscopic treatment was performed first in three patients with active bleeding. After coil embolization of collateral veins, stepwise EOI infusion was performed at intervals of 10–30 minutes under balloon occlusion until the main efferent vein, varices, and the main afferent vein were filled with EOI and clots. The techniques and outcomes of BRTO were retrospectively evaluated. Results: The main efferent vein of duodenal varices was the right (n = 4) or left (n = 2) gonadal vein. In three patients with ruptured varices, BRTO was performed after achieving hemostasis by endoscopic treatment. In five patients, 1–4 (mean, 2.4 ± 1.1) collateral veins were embolized with coils before EOI infusion. Furthermore, 11–21 mL (mean, 15.3 ± 4.2 mL) of EOI was infused by 3–5 (mean, 3.5 ± 1.0) stepwise infusions via the efferent vein under balloon occlusion. The duration of EOI infusion under balloon occlusion ranged from 82 to 118 minutes (mean, 87.8 ± 13.6 minutes). The varices were thrombosed in all but one patient. In the remaining patient, the varices were thrombosed by additional BRTO under overnight balloon occlusion performed 19 days later. The only complications were a transient fever and hematuria. All duodenal varices disappeared during a followup of 4–32 months (mean, 16.2 ± 11.1 months) after BRTO. Conclusion: BRTO using EOI is an effective treatment for duodenal varices.
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Electrical conduction properties of La-substituted bismuth titanate single crystals
Masaru Miyayama,Yuji Noguchi,Masatake Takahashi 한양대학교 세라믹연구소 2005 Journal of Ceramic Processing Research Vol.6 No.4
Single crystals of lanthanum-substituted bismuth titanate were grown by a self-flux method, and electrical conductivities were investigated at high temperatures. Lanthanum substitution suppressed Bi vaporization during annealing and decreased the electrical conductivity in both the a- and c-axes. It is suggested that lanthanum substitution stabilizes the perovskite blocks and hence decreases the concentrations of oxygen vacancies and holes as the conduction carriers. An ab-initio calculation indicated that the formation energy of an oxygen vacancy in the perovskite block is increased by lanthanum substitution, supporting the above experimental results.
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Shiro Miyayama,Masashi Yamashiro,Rie Ikeda,Junichi Matsumoto,Nobuhiko Ogawa,Kazuo Notsumata 소화기인터벤션의학회 2022 International journal of gastrointestinal interven Vol.11 No.1
Background: Bleeding from duodenal varices is a rare but life-threatening complication of portal hypertension. The treatment of duodenal varices remains difficult and a definitive treatment strategy has not been established. The aim of this study was to report the technical aspects and outcomes of balloon-occluded retrograde transvenous obliteration (BRTO) using 5% ethanolamine oleate with iopamidol (EOI) for duodenal varices. Methods: Six consecutive patients with duodenal varices treated using BRTO were eligible. Endoscopic treatment was performed first in three patients with active bleeding. After coil embolization of collateral veins, stepwise EOI infusion was performed at intervals of 10–30 minutes under balloon occlusion until the main efferent vein, varices, and the main afferent vein were filled with EOI and clots. The techniques and outcomes of BRTO were retrospectively evaluated. Results: The main efferent vein of duodenal varices was the right (n = 4) or left (n = 2) gonadal vein. In three patients with ruptured varices, BRTO was performed after achieving hemostasis by endoscopic treatment. In five patients, 1–4 (mean, 2.4 ± 1.1) collateral veins were embolized with coils before EOI infusion. Furthermore, 11–21 mL (mean, 15.3 ± 4.2 mL) of EOI was infused by 3–5 (mean, 3.5 ± 1.0) stepwise infusions via the efferent vein under balloon occlusion. The duration of EOI infusion under balloon occlusion ranged from 82 to 118 minutes (mean, 87.8 ± 13.6 minutes). The varices were thrombosed in all but one patient. In the remaining patient, the varices were thrombosed by additional BRTO under overnight balloon occlusion performed 19 days later. The only complications were a transient fever and hematuria. All duodenal varices disappeared during a followup of 4–32 months (mean, 16.2 ± 11.1 months) after BRTO. Conclusion: BRTO using EOI is an effective treatment for duodenal varices.
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Crystal Structure and Polarization Properties of Ferroelectric Bi4−xLaxTi3O12 Single Crystals
Masaru Miyayama,Yuji Noguchi,Masayuki Soga 한국물리학회 2009 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.55 No.2
Single crystals of ferroelectric Bi4Ti3O12 (BiT) and La-substituted Bi4Ti3O12 (BLT) were grown by using a self-flux method, and the effects of La substitution on the crystal structure, the polarization properties, and the domain structure were investigated. BLT crystals showed a smaller remanent polarization along the a axis compared with BiT, which is in good qualitative agreement with the spontaneous polarization calculated from the structural data determined from the neutron diffraction analysis. La substitution resulted in a decrease in the domain width of 90 degree domains, which is attributed in part to the smaller structural distortion a/b for BLT. Single crystals of ferroelectric Bi4Ti3O12 (BiT) and La-substituted Bi4Ti3O12 (BLT) were grown by using a self-flux method, and the effects of La substitution on the crystal structure, the polarization properties, and the domain structure were investigated. BLT crystals showed a smaller remanent polarization along the a axis compared with BiT, which is in good qualitative agreement with the spontaneous polarization calculated from the structural data determined from the neutron diffraction analysis. La substitution resulted in a decrease in the domain width of 90 degree domains, which is attributed in part to the smaller structural distortion a/b for BLT.
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Ultraselective conventional transarterial chemoembolization: When and how?
Shiro Miyayama 대한간학회 2019 Clinical and Molecular Hepatology(대한간학회지) Vol.25 No.4
Ultraselective conventional transarterial chemoembolization (cTACE), defined as cTACE at the most distal portion of the subsubsegmental hepatic artery, is mainly performed for hepatocellular carcinoma (HCC) ≤5 cm. Distal advancement of a microcatheter enables injection of a larger volume of iodized oil into the portal vein in the limited area under non-physiological hemodynamics. As a result, the reversed portal flow into the tumor through the drainage route of the tumor that occurs when the hepatic artery is embolized is temporarily blocked. By adding gelatin sponge slurry embolization, both the hepatic artery and portal vein are embolized and not only complete necrosis of the tumor but also massive peritumoral necrosis can be achieved. Ultraselective cTACE can cure small HCCs including less hypervascular tumor portions and replace surgical resection and radiofrequency ablation in selected patients.
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Defect control for polarization switching in BiFeO<sub>3</sub> single crystals
Chishima, Yuji,Noguchi, Yuji,Kitanaka, Yuuki,Miyayama, Masaru IEEE 2010 and Frequency Control Vol.57 No.10
<P>BiFeO<SUB>3</SUB> (BFO) single crystals were grown and the effects of Zn and Mn co-doping on the polarization and leakage current properties were investigated at 25°C for establishing materials design based on defect chemistry. Although Zn doping or Mn doping led to a deterioration in the properties, Zn-Mn co-doping led to a large remanent polarization (36 μC/cm<SUP>2</SUP>), a low coercive field (19 kV/cm), and a relatively low leakage current density (~10<SUP>-8</SUP> A/cm<SUP>2</SUP>). It is proposed that defect dipoles composed of Zn<SUP>2+</SUP> and Mn<SUP>4+</SUP> act as effective nucleation sites for ferroelectric domains during polarization switching in BFO crystals.</P>
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Ken Yanai,Hiroaki Onozuka,Yuuki Kitanaka,Yuji Noguchi,Masaru Miyayama,Chikako Moriyoshi,Yoshihiro Kuroiwa,Kousuke Kurushima,Shigeo Mori 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.62 No.7
Single crystals of ferroelectric (Bi<SUB>0.5</SUB>Na<SUB>0.5</SUB>)TiO<SUB>3</SUB> were successfully grown by the top-seeded solution growth method at a high oxygen pressure of 0.9쟋Pa and their polarization switching dynamics along <100><SUB>c</SUB> and their domain structures were investigated. Piezoelectric force microscope (PFM) observations show that BNT crystals poled along <100><SUB>c</SUB>. had 71-degree domains in which the spontaneous polarization (<I>P</I><SUB>s</SUB>) vector is opposite to the poling electric fields. Synchrotronradiation single-crystal X-ray diffraction analyses and the PFM observations reveal that the polarization switching in the BNT crystals along <100><SUB>c</SUB> is achieved by a 71-degree rotation of the <I>P</I><SUB>s</SUB> vector.
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