컴퓨터 赤外線 全身體熱撮影과 FNT을 통해 살펴본 Bell's palsy에 대한 침치료의 臨床的 考察

尹敏永,趙恩嬉,許泰永,趙南根,文炯喆 한국전통의학연구소 2001 한국전통의학지 Vol.11 No.1

Object : This study is designed to evaluate the clinical therapy of acupuncture by the data of DITI(Digital Infrared Thermographic Imaging) and FNT(Facial Nerve stimulation Test) examination and the changes of clinical symptoms after the therapy of acupuncture in the patients with Bell's palsy. Contents : The conservative therapy with acupuncture was performed during 1-8weeks. The acupuncture points of S4, S6, G14, S2, BL2, SI18, TE23, LI4 and S36 were used. In the pre- and post therapy, DITI examinations was performed in patients who had Bell's palsy and were treated by acupuncture, and then tried to correlate the results of clinical symptoms with the difference of thermographic findings. And FNT examinations were performed in the same patients above, and then tried to correlate the results of clinical symptoms with the difference of nerve response findings. Setting : The standard routine thermographic examination with thermography (DITI) and nerve response with FNT(Facial Nerve Stimulation Test) were performed in the 16 patients with Bell's palsy at pre- and post acupuncture. Patients : Thermographic imaging of 16cases was analyzed. They had diagnosed Bell's palsy. They were treated by acupuncture and moxibustion therapy in Wonkwang Oriental Hospital from Jauary, 1999 to February, 2000. Results : 1) The results of treatment showes that 56.25% of patients achieved clinical excellent recovery and 31.25% achieved good recovery. After compairing the DITI results before and after treatment, we found 43.75% of patients achieved excellent recovery and 43.75% achieved good recovery. 2) After compairing the FNT results before and after treatment, we found 25% of patients achieved excellent recovery and 56.25% achieved good recovery. Conclusion : 1) Acupuncture showed good results over 87.5% in clinical evaluation and 87.5% in DITI. Thermographic examination showes terapeutic effect of acupuncture treatment. 2) Acupuncture showed good results over 87.5% in clinical evaluation and 81.25% in FNT. FNT showes nerve response recovery effect of acupuncture treatment.

側腦室內 d-Tubocurarine이 家兎 腎臟機能에 미치는 影響

盧熙壯,許康敏,李載欣,昔廷鎬 충남대학교 의과대학 지역사회의학연구소 1989 충남의대잡지 Vol.16 No.1

Effect of d-tubocurarine administered intracerebroventricularly on the renal function of rabb-its was investigated. 1) Intraventricular d-tubocurarine induced decrease of urine flow, renal plasma flow, glomerular filtration, and urinary sodium and potassium excretion, but increase of reabsorption of urinary sodium and potassium. 2) Correlation coefficient between changes of two parameters among urine volume, renal plasma flow, glomerular filtration and urinary sodium excretion was statistically significant. 3) Changes of various parameters of renal function induced by intraventricular d-tubocurarine were inhibited by phenol treatment on the renal artery except change of sodium. From the above results, it is suggested that the effect of intraventricular d-tubocurarine on the renal function of rabbit is due to renal hemodynamic changes by central sympathetic activation.

갈륨과 아말감 수복물의 변연미세누출에 관한 비교 연구

이민호,이희주,허복 大韓齒科保存學會 1998 Restorative Dentistry & Endodontics Vol.23 No.1

This in vitro study compared the microleakage of 4 lining conditions when used with Gallium alloy GF Ⅱ and Valiant PhD. Class V cavity was prepared on both buccal and lingual surface of 80 extracted human premolar & molar teeth with one margin in enamel and another in dentin. Before restoration, prepared cavities were applied to no-liner, cavity varnish, Scotchbond multipurpose, and Superbond D-liner Ⅱ plus according to manufacture's instructions. The restored teeth were stored in saline for 1 week, then thermo-cycled for 100 times, stained with 0.5% basic fuchsin dye for 1 day, sectioned, and observed using a light microscope. Following results were obtained. 1. The leakage value of Superbond-lined group showed significantly lower than that of no-lined group on both margins of Valiant PhD(p<0.05). 2. There was no significant difference between the 4 lining conditions in Gallium alloy GFⅡ (p>0.05). 3. When We make a comparison between Gallium alloy GF Ⅱ and Valiant PhD under same lining conditions, the microleakage value of Gallium alloy GF Ⅱ showed lower than that of Valiant PhD on occlusal & gingival margin(p<0.05) except for Superbond-lined group(p>0.05).

Porter의 산업구조분석모형을 이용한 TFT-LCD 사업매력도 분석

이선규,이웅희,서명지,허연호,홍민정 금오공과대학교 산업기술개발연구원 2001 産業技術開發硏究 Vol.17 No.-

This study examined the key success factors and the degree of industry attractiveness in the TFT-LCD industries. The five competitive force factors include: barriers o entry, industry rivalry, threat of substitutes, supplier power and buyer power. As the result of this study, it was found that the key success factors were customer needs, high screen quality, low price, high performance, convenience and stability concerning with display device. This study provides another link in the chain of understanding of the industry attractiveness and key success factors in the TFT-LCD markets.

[P239] A case of recurrent acute paronychia

( Min Seok Hur ),( Joo Ran Hong ),( Hye In Cheon ),( Song Hee Han ),( Byung Gon Choi ),( Hae Jeong Youn ),( Min Jung Kim ),( Yang Won Lee ),( Yong Beom Choe ),( Kyu Joong Ahn ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

While acute paronychia is usually caused by bacterial infection, chronic paronychia is a multifactorial inflammatory disease of the nail apparatus due to irritants and allergens. Recurrent acute paronychia may evolve into chronic paronychia. A 23-year-old female was referred to our dermatologic clinic with an erythematous and edematous proximal nail fold of right forth finger. She had been treated with nail extraction and antifungal agent in the diagnosis of acute paronychia due to bacterial and fungal infection. The lesion seemed to be improved but aggravated with abscess formation. We drained pus and carried out wound culture and KOH smear, but we could not get pathogenic findings. We tried cefadroxil and nonsteroidal anti-inflammatory drugs with nail extraction. Despite of repeated treatments, her problem didn’t seem to be improved. For management of recurrent acute paronychia, we decided to add anti-pseudomonal agent to previous treatment. The lesion has kept improved state without relapse. We report an interesting case of recurrent acute paronychia refractory to treatment with antibiotics, antifungal agents and surgical management.

[P056] A case of acquired palmoplantar keratoderma treated with keratolytics and retinoids

( Min Seok Hur ),( Joo Ran Hong ),( Hye In Cheon ),( Song Hee Han ),( Byung Gon Choi ),( Hae Jeong Youn ),( Min Jung Kim ),( Yang Won Lee ),( Yong Beom Choe ),( Kyu Joong Ahn ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Palmoplantar keratodermas (PPKs) are disorders with variable causes that are characterized by abnormal hyperkeratosis of the palms and soles. They have been classified as either hereditary or acquired PPKs. The clinical characteristics of acquired PPKs are non-hereditary, non-frictional skin thickening involving acral areas. A 33-year-old woman presented with nonsymptomatic hyperkeratotic patches on palms and soles. She had neither medical history nor family history of keratoderma. We had applied topical keratolytic agent (salicylic acid) for four months, followed by alitretinoin. After four months of the treatment with alitretinoin, she showed clinical improvement. Herein we report a patient with PPK with unknown etiology that led to the diagnosis of acquired PPK. This report would be helpful to suggest successful treatment of acquired PPKs with keratolytics and retinoids.

P011 Antioxidant functions of kinetin on damage keratinocytes by hydrogen peroxide

( Min Seok Hur ),( Hye In Cheon ),( Byung Gon Choi ),( Song Hee Han ),( Min Jung Kim ),( Hae Jeong Youn ),( Soo Young Kim ),( Nam Kyung Roh ),( Yang Won Lee ),( Yong Beom Choe ),( Kyu Joong Ahn ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2

<div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div> Background: Hydrogen peroxide (H2O2) is a species of reactive oxygen, affects to fate of cells in growth, senescence, and extinction. H2O2 is unstable property because of free radicals. As unstable property, H2O2 reacts strong with other molecules and damage to cells and DNA. Kinetin, plant cytokinins, regulates plant growth. It has been reported that kinetin has antioxidant effects, synthesis promotion of DNA, and senescence delay on dermal fibroblast in cellular function. But there is no study reported in effects of kinetin on keratinocytes. Objectives: This study aimed to verify functions of kinetin as a raw material for cosmetics products in skin through the cell efficacy test. Methods: To verify the efficacy of kinetin on HaCaT human keratinocyte cells, the cell viability essay, and reactive oxygen species (ROS) assay were performed. As kinetin with concentrations of 200 μM and above were toxic in HaCaT cells, this study used kinetin with concentrations of less than 200 μM. Results: Cell viability assay showed that kinetin efficiently rescued HaCaT cells from H2O2-induced oxidative stress damages in a concentration-dependent manner. Furthermore, flow cytometry analysis revealed that kinetin decreased the intracellular ROS levels in H2O2-treated HaCaT cells. Conclusion: These data indicated that kinetin can be used as a raw effective natual material for for functional cosmetic products which can reduce facial wrinkles, came from ROS, and improve the condition and function of skin.

Multicenter survey of herpes zoster in Korea: awareness, knowledge, and vaccine acceptability

( Min Seok Hur ),( Hye In Cheon ),( Byung Gon Choi ),( Song Hee Han ),( Min Jung Kim ),( Hae Jeong Youn ),( Soo Young Kim ),( Nam Kyung Roh ),( Yang Won Lee ),( Yong Beom Choe ),( Kyu Joong Ahn ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2

Background: Herpes zoster (HZ) infection can significantly impair the quality of life of the affected individuals, and its treatment imposes a considerable cost burden on the health-care system and on society at large. However, there is little information on the perception of this disease and the acceptability of vaccines in Korea. Objective: The aim of this study is to determine the awareness of HZ and its vaccine, and to identify factors associated with the acceptability of the HZ vaccine among outpatients of dermatology clinics. Methods: A questionnaire-based survey was conducted on 607 outpatients who visited the dermatologic clinics. Results: The responses of the patients revealed a high awareness of HZ (85.4%) but a relatively low knowledge about HZ and its vaccine (42.3%). The HZ vaccination rate among patients aged ≥50 years was 9%. A history of HZ infection, being older, and greater knowledge about HZ and its vaccine were associated with a higher HZ vaccine acceptability. Of those who had not been vaccinated, 58.3% were interested in receiving the vaccine. The most frequent reason for this interest was “severe sequelae,” followed by “knowing someone who has HZ” and “recommendation from a doctor.” High cost was the most common reason for unwillingness to receive the vaccination. Conclusion: Despite a high awareness of HZ, vaccine acceptability was extremely low among this study cohort. Vaccination acceptability would be improved by encouraging doctors to educate elderly patients about the disease and the availability of vaccination, and by the provision of insurance coverage for HZ vaccination.

Importance of taxonomic research for biodiversity of Korea

Hur, Wee-Haeng,Park, Chan-Ho,Min, Gi-Sik,Hyun, Chang-Woo,Bae, Eun Hee,Lee, Jeong Hyun,Jung, Eun-Hee,Yoo, Jung-Sun,Suh, Min Hwan The National Institute of Biological Resources 2016 Journal of species research Vol.5 No.3

In 2012, the NIBR started publishing the Journal of Species Research (JSR) as an international specialized journal of biological taxonomy focusing on taxonomic research. JSR Volume 5 Number 3, to be published in October 2016, has been planned as a 'Special Edition on New and Unrecorded Species of Invertebrates in Korea', and so it consists of the reports of 149 new and unrecorded invertebrate species (including protozoa) discovered in Korea. In future, the JSR should further accelerate the use of such methods to generate valid data for new species and effectively support the compilation of 'National List of Species of Korea'. In this way, it will contribute significantly to enrich for biodiversity in Korea.

[P220] A case of multiple basal cell carcinoma in xeroderma pigmentosum treated with CO₂ laser and ingenol mebutate gel

( Min Seok Hur ),( Joo Ran Hong ),( Hye In Cheon ),( Song Hee Han ),( Byung Gon Choi ),( Hae Jeong Youn ),( Min Jung Kim ),( Yang Won Lee ),( Yong Beom Choe ),( Kyu Joong Ahn ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Xeroderma pigmentosum (Xp) is a rare autosomal recessive disorder of DNA repair, with a prevalence of 1 in 1 million individuals. It is characterized by extreme sensitivity to sunlight, resulting in sunburn, pigment changes in the skin, a high incidence of skin cancer, and developmental disorders. A 12-year-old girl presented with multiple scaly patches of various sizes and nodules on her face. Histological diagnosis revealed basal cell carcinoma. In addition to the malignancy, she had a pigmentaryabnormality, hypersensitivity to sunlight, neurological hearing loss, intellectual deficiency, and developmental delay. In accordance with the symptoms and findings, she was clinically diagnosed as having Xp. We used carbon dioxide laser to treat the malignant lesions and treated the other small scaly papules with 0.015% ingenol mebutate gel to prevent cancer related to Xp. Herein we report a case of early onset skin cancer occurring in a patient with severe form of Xp.