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      저자 : Miju Cheon (검색결과 2 건)
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        Diagnostic Performance of 18F-Fluorodeoxyglucose Positron Emission Tomography/CT for Chronic Empyema-Associated Malignancy

        Miju Cheon,유장,Seung Hyup Hyun,이경수,Hojoong Kim,김진국,Jae Il Zo,Young Mog Shim,Joon Young Choi 대한영상의학회 2019 Korean Journal of Radiology Vol.20 No.8

        Objective: The purpose of this study was to evaluate the diagnostic performance of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) for chronic empyema-associated malignancy (CEAM). Materials and Methods: We retrospectively reviewed the 18F-FDG PET/CT images of 33 patients with chronic empyema, and analyzed the following findings: 1) shape of the empyema cavity, 2) presence of fistula, 3) maximum standardized uptake value (SUV) of the empyema cavity, 4) uptake pattern of the empyema cavity, 5) presence of a protruding soft tissue mass within the empyema cavity, and 6) involvement of adjacent structures. Final diagnosis was determined based on histopathology or clinical follow-up for at least 6 months. The abovementioned findings were compared between the 18F-FDG PET/CT images of CEAM and chronic empyema. A receiver operating characteristic (ROC) analysis was also performed. Results: Six lesions were histopathologically proven as malignant; there were three cases of diffuse large B-cell lymphoma, two of squamous cell carcinoma, and one of poorly differentiated carcinoma. Maximum SUV within the empyema cavity (p < 0.001) presence of a protruding soft tissue mass (p = 0.002), and involvement of the adjacent structures (p < 0.001) were significantly different between the CEAM and chronic empyema images. The maximum SUV exhibited the highest diagnostic performance, with the highest specificity (96.3%, 26/27), positive predictive value (85.7%, 6/7), and accuracy (97.0%, 32/33) among all criteria. On ROC analysis, the area under the curve of maximum SUV was 0.994. Conclusion: 18F-FDG PET/CT can be useful for diagnosing CEAM in patients with chronic empyema. The maximum SUV within the empyema cavity is the most accurate 18F-FDG PET/CT diagnostic criterion for CEAM.

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        How Computed Tomography Contrast Media and Magnetic Resonance Imaging Contrast Media Affect the Changes of Uptake Counts of <SUP>201</SUP>Tl

        Jin-Hyeok Lee,Hae-Kag Lee,Jae-Hwan Cho,Miju Cheon 한국자기학회 2014 Journal of Magnetics Vol.19 No.4

        The purpose of the study is to investigate how uptake counts of <SUP>201</SUP>Tl of radioisotopes in the human body could change, when taking computed tomography and magnetic resonance imaging right after injecting contrast media.<SUP> 201</SUP>Tl radioisotope substances of iodine contrast medium, which is a computed tomography contrast medium, and paramagnetic contrast medium, which is an magnetic resonance imaging contrast medium, were used as study materials. First, <SUP>201</SUP>Tl was put into 4 cc of normal saline in test tube, and then a computed tomography contrast medium of Iopamidol<SUP>®</SUP> or Dotarem<SUP>®</SUP>, was put into 2 cc of normal saline in test tube. An magnetic resonance imaging contrast medium of Primovist<SUP>®</SUP> or Gadovist<SUP>®</SUP> was also put into 2 cc of normal saline in test tube. Each contrast medium was distributed to make <SUP>201</SUP>Tl as 3 mCi, with a total of 4 cc. Gamma camera, low energy high resolution collimator, and pinhole collimator were used to obtain images. The uptake count of<SUP> 201</SUP>Tl was measured with 1000 frames of images, and obtained after 10 times of repetition. This study revealed that the use of Gadovist<SUP>®</SUP>, which is an magnetic resonance imaging contrast medium, showed the smallest number of uptake count, after measuring <SUP>201</SUP>Tl uptake count by low energy high resolution collimator. On the other hand, the use of Iopamidol<SUP>®</SUP>, which is a computed tomography contrast medium, showed the biggest difference in uptake count, when measuring <SUP>99m</SUP>Tc uptake count by Pinhole collimator. When examining with gamma camera, using contrast medium and <SUP>201</SUP>Tl, identifying the changes of uptake count is very important for improving the value of diagnosis.

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