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RISS 인기검색어
- 검색키워드
- 저자 : Merve Aydin (검색결과 4 건)
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Design and analysis of non-linear space frames with semi-rigid connections
Merve Sagiroglu,Abdulkadir Cuneyt Aydin 국제구조공학회 2015 Steel and Composite Structures, An International J Vol.18 No.6
Semi-rigid connections are the actual behavior of beam-to-column connections in steel frames. However, the behavior of semi-rigid connections is not taken into account for the simplicity in the conventional analysis and design of steel frames. A computer-based analysis and design has been studied for the three-dimensional steel frames with semi-rigid connections. The nonlinear analysis which includes the effects of the flexibility of connections is used for this study. It is designed according to the buckling and combined stress constraints under the present loading after the joint deformations and the member end forces of the space frame are determined by the stiffness matrix method. The semi-rigid connection type is limited to the top and bottom angles with a double web angle connection. The Frye-Morris polynomial model is used to describe the non-linear behavior of semi-rigid connections. Various design examples are presented to demonstrate the efficiency of the method. The results of design and analysis of unbraced semi-rigid frames are compared to the results of unbraced rigid frames under the same design requirements.
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Gungor, Merve Bankoglu,Yilmaz, Handan,Aydin, Cemal,Nemli, Secil Karakoca,Bal, Bilge Turhan,Tiras, Tulay The Korean Academy of Prosthodonitics 2014 The Journal of Advanced Prosthodontics Vol.6 No.3
PURPOSE. The purpose of the present study was to evaluate the effect of thermocycling and mechanical loading on the biaxial flexural strength and the phase transformation of one Ce-TZP/$Al_2O_3$ and two Y-TZP core materials. MATERIALS AND METHODS. Thirty disc-shaped specimens were obtained from each material. The specimens were randomly divided into three groups (control, thermocycled, and mechanically loaded). Thermocycling was subjected in distilled water for 10000 cycles. Mechanical loading was subjected with 200 N loads at a frequency of 2 Hz for 100000 times. The mean biaxial flexural strength and phase transformation of the specimens were tested. The Weibull modulus, characteristic strength, 10%, 5% and 1% probabilities of failure were calculated using the biaxial flexural strength data. RESULTS. The characteristic strengths of Ce-TZP/$Al_2O_3$ specimens were significantly higher in all groups compared with the other tested materials (P<.001). Statistical results of X-ray diffraction showed that thermocycling and mechanical loading did not affect the monoclinic phase content of the materials. According to Raman spectroscopy results, at the same point and the same material, mechanical loading significantly affected the phase fraction of all materials (P<.05). CONCLUSION. It was concluded that thermocycling and mechanical loading did not show negative effect on the mean biaxial strength of the tested materials.
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Asymmetrical Dimethylarginine Levels in Hepatitis B Virus-Positive Patients
Faruk Karakecili,Aytekin Cikman,Merve Aydin,Baris Gulhan 대한진단검사의학회 2018 Annals of Laboratory Medicine Vol.38 No.5
Background: High asymmetrical dimethylarginine (ADMA) levels have been associated with endothelial dysfunction and contribute to the development of several diseases. However, data on the relationship between hepatitis B virus (HBV) and ADMA are limited. The aim of our study was to explore the relationship between ADMA and HBV by comparing the ADMA levels in patients with chronic active hepatitis B (CHB), inactive HBV carriers (carriers), and healthy volunteers (controls). Methods: The participants were divided into three groups: 90 patients with CHB, 90 HBV carriers, and 90 controls. Serum ADMA levels were quantified using an ELISA kit (Cusabio, Wuhan, China). The data were analyzed using an ANOVA or the Kruskal-Wallis test as appropriate, with P<0.05 considered significant. Results: Serum ADMA levels were significantly higher in patients with CHB (228.35±91.10 ng/mL) than in HBV carriers (207.80±75.80 ng/mL) and controls (207.61±89.10 ng/mL) (P=0.049). The clinical scores of the patients were positively correlated with ADMA levels. Conclusions: The elevated serum ADMA levels in patients with CHB confirm that HBV plays a role in vasculitis. Further investigation of the mechanisms contributing to the high levels of ADMA in CHB may contribute toward development of new treatment modalities
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Ellidag, Hamit Yasar,Aydin, Ozgur,Eren, Esin,Yilmaz, Necat,Ergin, Merve Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.22
Background: Multiple myeloma (MM) is a haematological cancer characterized by clonal proliferation of plasma cells.The aim of this study was to investigate the activity of serum paraoxonase-1 (PON1) and arylesterase (ARE) in multiple myeloma with and without free light chain excretion(FLCe-MM and NFLCe-MM); as well as to investigate possible alterations in oxidative stress parameters. Materials and Methods: Total thiol (T.thl), oxidative stress index (OSI), total oxidant status (TOS) and total antioxidant status (TAS) were examined in addition to the PON1 and ARE enzyme activities in twenty one FLCe-MM and nineteen NFLCe-MM subjects. Routine parameters like lipid panel, serum total protein, albumin, creatinine, blood urea nitrogen (BUN), uric acid and hemoglobin levels were compared with the oxidative stress markers. Results: Serum total protein, BUN, creatinin, and uric acid levels were significantly higher (p=0.04, p=0.001, p=0.001 and p=0.0022, respectively), while hemoglobin and albumin levels were significantly lower in FLCe-MM patients (p=0.009 and p=0.04,respectively). PON1 and ARE activities were significantly lower in patients with FLCe-MM compared to those with NFLCe-MM (p=0.001 and p=0.008, respectively). Conclusions: Depending on our results of prognostic markers of MM such as age, hemoglobin, albumin, and creatinine we feel confident to presume FLCe-MM as a subgroup with a worse prognosis. A decrease in PON1 and ARE activities may contribute to the prognosis and may be used as a prognostic tool in MM.
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