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Design and Fabrication of Crawling Inchworm Robot
Mehrdad Ahmadi(매흐다드 아마디),Roushanak Haji Hassani(로샤낙 허지 하싸니),Kuk Won Ko(고국원) 한국산학기술학회 2014 한국산학기술학회 학술대회 Vol.- No.-
Movement in the complex and impassable paths has been always a concern for robotic engineers. Inspiring from the nature can provide a solution for this problem. Due to special locomotion of worms, they are able to pass uneven terrains. In this paper, firstly, the locomotion model of a real inchworm is reviewed. Then, this model is simulated and acquired data, are verified by experimental results which are provided from a fabricated prototype robot. The obtained results show a forward motion as desired.
Payandeh, Mehrdad,Shahriari-Ahmadi, Ali,Sadeghi, Masoud,Sadeghi, Edris Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.3
Background: Overexpression or amplification of human epidermal growth factor receptor-2 (HER2) is associated with grade of malignancy and a poor prognosis in breast cancer (BC). The aim of this study was to evaluate of value of HER2 as a prognostic marker, and to analyze associations with common histopathological parameters in BC cases. Materials and Methods: Between of 2007 to 2014, 260 patients with BC referred to Oncology Clinic provided cancer tissue samples which underwent immunohistochemistry (IHC) for markers. ER and PR positivity was defined as ${\geq}10%$ positive tumor cells with nuclear staining. HER2-positive was defined as either HER2 gene amplification by fluorescent in situ hybridization (FISH) or scored as 3+ by IHC. For HER2 (2+), FISH was performed to determine HER2 positivity. Results: The mean age at diagnosis for the patients with HER2-negative was significantly higher than in HER2-positive cases. Also, there were significant correlations between histological grade, nuclear grade, lymph node metastasis, tumor size, ER status, PR status, p53 overexpression and Ki-67 index with HER2 expression. HER2-negative lesions were of higher grade and more likely to be ER-negative, PR-negative, p53-positive, lymph node metastasis, with a tumor size<2cm and also $Ki-67{\geq}20%$ as compared to the HER2-positive group. Conclusions: Contrary to the results of other studies, HER2-positive tumors in our study had a lower Ki-67 index and were p53-positive. Also, Ki-67 proliferation index ${\geq}20%$ in more studies was associated with p53-positive.Therefore, tumors which are HER2-positive and have a Ki-$67{\geq}20%$ had a more aggressive behavior compared to HER2-positive and Ki-67<20% lesions.
Karimi Mehrdad,Kazemi Amir Hooman,Nareswari Irma,Zarei Azadeh,Zargaran Arman,Moravej Seyed Ali Al-hadi,Jazayeri Seyede Ferdos,Nabavian Omid,Ahmadi Seyedeh Aida,Alipour Reihane 사단법인약침학회 2022 Journal of Acupuncture & Meridian Studies Vol.15 No.3
Acute respiratory distress syndrome (ARDS) is commonly found in critically ill patients with coronavirus disease 2019 (COVID-19). As a non-pharmacological treatment of complementary and alternative medicine (CAM), cupping has been clinically used for respiratory symptoms. We sequentially identified a series of patients with COVID-19 with ARDS who were admitted to the intensive care unit (ICU). Warm cupping of the posterior thorax was performed for seven days. We collected longitudinal severity scores on cough, breathlessness, chest tightness, type of oxygen therapy, and oxygen saturation (SpO 2 ). We hereby report the changes in the severity scores in a series of eight patients who received 21 sessions of cupping in addition to conventional treatments. All patients reported improvement in symptom scores that was matched by an increase in SpO 2 by as much as 3.16%. All patients were discharged and did not require the use of a mechanical ventilator. The results suggest that combining cupping with conventional treatment may provide a good prognosis for patients with COVID-19 with ARDS.
Shahriari-Ahmadi, Ali,Fahimi, Ali,Payandeh, Mehrdad,Sadeghi, Masoud Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.17
Background: The chemotherapeutic agent oxaliplatin can cause acute and chronic forms of peripheral neuropathy. The aim of this study was to evaluate the incidence of chronic neuropathy and its risk factors in colorectal cancer (CRC) patients treated with FOLFOX or XELOX regimens in the Oncology Ward of Hazrate-Rasoul Hospital in Tehran. Materials and Methods: A total of 130 patients with CRC were entered into our study, aged over 18 years, without history of receiving other neurotoxic agents or other predisposing factors such as diabetes or neurologic diseases and kidney and liver dysfunction. For the FOLFOX regimen, patients received oxaliplatin, 85mg/m2, every 2 weeks for 12 courses and with the XELOX regimen, oxaliplatin was $130mg/m^2$, every 3 weeks for 8 courses. Based on Common Toxicity Criteria (CTC or NCI-CTC v.3), the patients were divided into 5 groups (grades) based on the severity of their symptoms. Results: Fifty-seven patients (43.8%) were male and 73(56.2%) female. Some 19 patients (14.7%) had BMI<20, 97(74.6%) were between 20-25 and 14 (10.8%) ${\geq}25$. In 105 patients (80.7%) neuropathy was found. There was significant correlation between BMI, hypomagnesaemia and especially, severity of anemia in patients with neuropathy compared to those without. Conclusions: Oxaliplatin regimens can induce chronic neuropathy in CRC patients, with anemia, high BMI and hypomagnesaemia as risk factors that can predispose to this kind of neurotoxicity.
Shohreh Asgarian Dehkordi,Mehrdad Ahmadi,BijanHatami 한국응용곤충학회 2018 Journal of Asia-Pacific Entomology Vol.21 No.4
With respect to the limitations use of methyl bromide and phosphine, employing ionizing radiation to control stored product pests has attracted great attention. The aim of this study is the investigation of the combined effects of gamma irradiation as viable alternatives to synthetic insecticides and environmental management on mortality and sterility of Rhyzopertha dominica (Fabricius) in a wheat cultivar (Gascogen). The effect of doses range from 30 to 2000 Gy gamma irradiation in combination with manipulation of temperature (15, 21, 27 and 32 °C) and relative humidity (20%, 50%, 65% and 85%) on 5–10 days old adults of R. dominica in Gascogen cultivar of wheat were explored. The experiments were repeated three times and conducted in The Nuclear Agriculture Research School in Karaj and laboratory of shahid steki silo in shahre-kord. Probit analysis revealed that both temperature and relative humidity had combined effects when used with gamma irradiation. The lowest doses of gamma ray required to kill 25% (14.2 Gy) and 50% (610.8 Gy) of the population (LD 25 and LD 50 ) were recorded at 21 °C and 85% relative humidity respectively. The low dose for 99% mortality (LD 99 ; 2386.7 Gy) was recorded for beetles maintained at 21 °C and 50% relative humidity. The effect of temperature (15, 21, 27 and 32 °C) on sterility caused by gamma irradiation was also investigated. The results showed that the F 1 generation emerged only when the beetles were treated with doses of 0–100 Gy at 32 °C and 0–70 Gy at 27 °C. These results indicate that temperature and relative humidity play an important role in the susceptibility of the lesser grain beetle to gamma irradiation. The results suggest that controlling the efficiency of gamma radiation through environmental control allows the use of low doses of gamma radiation that have a less harmful effect on human health, non-target organisms and seed agronomic features.
김동현(Dong Hyun Kim),매흐다드 아마디(Mehrdad Ahmadi),고국원(Kuk Won Ko) 한국산학기술학회 2014 한국산학기술학회 학술대회 Vol.- No.-
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