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        Tumor Occupation in the Spinal Canal and Clinical Symptoms of Cauda Equina Schwannoma: An Analysis of 22 Cases

        Kengo Fujii,Masataka Sakane,Tetsuya Abe,Tsukasa Nakagawa,Shinsuke Sakai,Masaki Tatsumura,Toru Funayama,Masashi Yamazaki 대한척추외과학회 2016 Asian Spine Journal Vol.10 No.6

        Study Design: Retrospective, radiological study. Purpose: To determine the relationship between clinical symptoms and the extent of tumor occupation of the spinal canal by cauda equina schwannoma. Overview of Literature: Little is known about the relationship between the size of tumors of the cauda equina and the manifestation of clinical symptoms. We analyzed this relationship by estimating the percentage of tumor occupation (PTO) in the spinal canal in cauda equina schwannomas and by correlating this parameter with the presence and severity of clinical symptoms. Methods: Twenty-two patients (9 men and 13 women; age, 19–79 years; mean age, 55.3 years) who were radiologically diagnosed with schwannomas of the cauda equina between April 2004 and July 2014 were retrospectively analyzed. PTO was measured in axial and sagittal magnetic resonance imaging slices in which the cross-sectional area of the tumor was the largest. Data regarding clinical symptoms and results of physical examinations were collected from patient medical records. PTO differences between symptompositive and -negative groups were analyzed for each variable. Results: In the 4 cases in which tumor presence was not related to clinical symptoms, PTO was 5%–10% (mean, 9%) in axial slices and 23%–31% (mean, 30%) in sagittal slices. In the 18 cases in which symptoms were associated with the tumor, PTO was 11%–86% (mean, 50%) in axial slices and 43%–88% (mean, 71%) in sagittal slices. PTO in axial slices was significantly higher in the presence of Déjèrine symptoms and/or muscle weakness, a positive straight leg raise test, and a positive Kemp sign. Conclusions: PTO >20% in axial slices and >40% in sagittal slices can be an indication of symptomatic cauda equina schwannoma.

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        Simultaneous Three-Dimensional Analysis of Cervical Spine Kinematics in the Axial and Sagittal Views during a Simulated Frontal Impact: Differences between Tensed and Relaxed States

        Keita Nakayama,Masataka Sakane,Susumu Ejima,Daisuke Ito,Tomofumi Nishino,Sou Kitajima,Masashi Yamazaki 대한척추외과학회 2015 Asian Spine Journal Vol.9 No.6

        Study Design: Prospective experimental study on humans. Purpose: To determine whether postural differences during a low-speed impact are observed in the sagittal and axial views, particularly in a relaxed state. Overview of Literature: Three-dimensional motion capture systems have been used to analyze posture and head-neck-torso kinematics in humans during a simulated low-speed impact, yet little research has focused on the axial view. Since a seatbelt asymmetrically stabilizes a driver’s right shoulder and left lower waist into the seat, it potentially creates movement in the axial view. Methods: Three healthy adult men participated in the experimental series, which used a low-speed sled system. The acceleration pulse created a full sine shape with a maximum acceleration of 8.0 m/s2 at 500 ms, during which the kinematics were evaluated in relaxed and tensed states. The three-dimensional motion capture system used eight markers to record and analyze body movement and head-neck-torso kinematics in the sagittal and axial views during the low-speed impact. Head and trunk rotation angles were also calculated. Results: Larger movements were observed in the relaxed than in the tensed state in the sagittal view. The cervical and thoracic spine flexed and extended, respectively, in the relaxed state. In the axial view, larger movements were also observed in the relaxed state than in the tensed state, and the left shoulder rotated. Conclusions: During simulated frontal impact, the rotation angle between the head and trunk was significantly larger in the relaxed state. Therefore, we recommend also observing movement in the axial view during impact tests.

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        Novel Unidirectional Porous Hydroxyapatite used as a Bone Substitute for Tibial Wedge Osteotomy in Canines

        Arata Watanabe,Masataka Sakane,Toru Funayama,Masashi Iwasashi,Akihiro Kanamori,Naoyuki Ochiai 한국생체재료학회 2010 생체재료학회지 Vol.14 No.1

        A microstructure of unidirectional porous hydroxyapatite (UDPHAp) has a diameter of 100-300 μm, which pene-trates through the material. In addition, it has a porosity of 75% and initial compression strength of approximately 14 MPa. The objective of the present study was to investigate the feasibility of UDPHAp for the tibial wedge osteot-omy in canines. We performed the operation on the right tibia of the dogs, and a wedge-shaped UDPHAp was implanted in the gap after the osteotomy. At 6 and 12 weeks after the operation, the specimens were solid and bony union could be macroscopically observed. Radiological examination revealed that complete consolidation between the osteotomy site and the UDPHAp was established at 12 weeks. Histological evaluation revealed fibrous tissues between the host bone and the UDPHAp at 6 weeks, although new bone formation was observed at the edges of the material. At 12 weeks, direct bonding and bone ingrowth was observed. This study indicates that UDPHAp has great potential for use as a bone substitute for open-wedge high tibail osteotomy in clinical condition.

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