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RISS 인기검색어
- 검색키워드
- 저자 : Maryam Mohamadi (검색결과 3 건)
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Maryam Mohammad-Sadeghipour,Mehdi Afsharinasab,Maryam Mohamadi,Mehdi Mahmoodi,Soudeh Khanamani Falahati-pour,Mohammad Reza Hajizadeh 대한비만학회 2020 The Korean journal of obesity Vol.29 No.3
Background: Metabolic syndrome (MetS) is a complex clinical disorder that can lead to an increase in oxidative stress. Patients with this syndrome are at risk of diabetes and cardiovascular disease. The Trigonella foenum-graecum L. (fenugreek) plant has many therapeutic effects, including anti-diabetic and antioxidant. The present study aimed to investigate the effects of the hydro-alcoholic extract of fenugreek seeds (HEFS) on dyslipidemia and oxidative stress due to high-fructose diet-induced MetS. Methods: In this experimental study, to induce MetS, animals received water containing 20% fructose for 8 weeks. After induction of MetS, 48 male Wistar rats (200–250 g) were randomized into six groups. HEFS was administered to animals at doses of 100 and 200 mg/kg orally for 4 weeks. Animal blood samples were collected to measure biochemical and antioxidant parameters of fasting plasma glucose (FPG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), malondialdehyde (MDA), glutathione peroxidase (GPX), catalase (CAT), and total antioxidant capacity (TAC). Results: The findings showed that the serum levels of FPG, TC, LDL-C, TG, and MDA were significantly reduced in HEFS-exposed groups compared with the control group (P<0.05). Also, significant increases in HDL-C, GPX, CAT, and TAC levels (P<0.05) were observed. Conclusion: Our results revealed that treatment with HEFS increases the levels of antioxidant enzymes, decreases FPG level, and at the same time, modifies the lipid profile in MetS. Therefore, HEFS may help to alleviate the risk of some chronic complications of this disease.
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Maryam Borhani-Haghighi,Shadan Navid,Yousef Mohamadi 대한척추외과학회 2020 Asian Spine Journal Vol.14 No.2
Study Design: Experimental animal study. Purpose: This study investigated the therapeutic effects of human breast milk stem cell (BMSC)-conditioned medium (BMSC-CM) in a model of spinal cord injury (SCI) in male Sprague-Dawley rats. Overview of Literature: SCI is one of the leading causes of disability in addition to sensory and motor impairment. So far, there have been no successful treatments for SCI. Given the positive outcomes associated with using stem cells and their derivatives as a treatment for various diseases, there is a growing interest in using them as an SCI treatment. Recent research has demonstrated that CM from stem cells has therapeutic advantages. Methods: Human BMSCs were isolated and characterized, and CM was subsequently collected. Animals received an intrathecal administration of BMSC-CM after SCI. The activity of caspase-3 was measured to assess apoptosis, and levels of tumor necrosis factor-α and interleukin-1β were measured to assess inflammation. Also, sensory and locomotor performances were assessed after SCI and BMSC-CM administration. Results: Administration of CM from BMSC reduced apoptosis and inflammation at the site of injury in a rat model of SCI (p <0.05). Motor, sensory, locomotor, and sensorimotor performances were significantly improved in rats that received BMSC-CM after SCI. Conclusions: Intrathecal administration of BMSC-CM improved recovery in a rat model of SCI.
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Somayeh Mohamadi Sodkouieh,Maryam Kalantari,Tayebeh Shamspur 한국화학공학회 2023 Korean Journal of Chemical Engineering Vol.40 No.4
Dyes are one of the major toxic pollutants discharged in large quantities into the hydrosphere. Among various dye removal methods, adsorption has a distinct position. In this study, wheat straw was used as a low-cost and renewable material to prepare two economical adsorbents through the facile production method. An adsorbent was prepared by alkaline hydrolysis of wheat straw. Then, another adsorbent was synthesized by carboxymethylation of the first adsorbent. The prepared adsorbents were characterized by various techniques, including Fourier transform infrared spectroscopy (FT-IR), field-emission scanning electron microscopy (FESEM), and X-ray diffraction (XRD). A series of adsorption experiments were conducted in a batch adsorption system to study the effect of diverse parameters, such as solution pH, the initial dye concentration, and contact time, on the adsorption performance. Adsorption models and kinetic results indicated that the adsorption of methylene blue onto both adsorbents was more fitted to Langmuir isotherm and followed second-order kinetics. The maximum monolayer adsorption capacity of methylene blue on alkaline-modified wheat straw and carboxymethylated modified wheat straw reached 131.123 and 191.427 mg/g, respectively. Regarding their low cost and suitable adsorption potential, they can be cost-effective and promising adsorbents for wastewater treatment.
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