Impacts of halloysite clay nanoparticles on the structural and γ-ray shielding properties of the epoxy resin

Mahmoud K.G.,Sayyed M.I.,Hashim S.,Almuqrin Aljawhara H.,El-Soad A.M Abu 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.4

In this study, halloysite nanoparticles-doped epoxy resin was synthesised using the casting method. The MH-300A density metre revealed that the density of the fabricated composites changed from 1.132 to 1.317 g/cm3 as the halloysite nanoparticle concentration increased. The Fourier transform infrared was recorded for the synthesised composites. Furthermore, the γ-ray shielding properties of the synthesised composites were evaluated using Monte Carlo simulation and a theoretical programme, XCOM. The linear attenuation coefficient of the epoxy resin increased by 43% (at γ-energy of 15 keV) and 14% (at γ-photon energy of 662 keV) when the concentration of the halloysite nanoparticles was increased from 0 wt% to 40 wt%, respectively.

Impacts of the calcination temperature on the structural and radiation shielding properties of the NASICON compound synthesized from zircon minerals

Alhindawy Islam G.,Gamal Hany,Almuqrin Aljawhara.H.,Sayyed M.I.,Mahmoud K.A. 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.5

The present work aims to fabricate Na1þxZr2SixP3-xO12 compound at various calcination temperatures based on the zircon mineral. The fabricated compound was calcinated at 250, 500, and 1000C. The effect of calcination temperature on the structure, crystal phase, and radiation shielding properties was studied for the fabricated compound. The X-ray diffraction diffractometer demonstrates that, the monoclinic crystal phase appeared at a calcination temperature of 250C and 500C is totally transformed to a highsymmetry hexagonal crystal phase under a calcination temperature of 1000C. The radiation shielding capacity was also qualified for the fabricated compounds using the Monte Carlo N-Particle transport code in the g-photons energy interval between 15keV and 122keV. The impacts of calcination temperature on the g-ray shielding behavior were clarified in the present study, where the linear attenuation coefficient was enhanced by 218% at energy of 122keV, when the calcination temperature increased from 250 to 1000C, respectively

Influence of Plant Extracts and Microbioagents on Physiological Traits of Faba Bean Infected with Botrytis fabae

( Yehia A. G. Mahmoud ),( Mohsen K. H. Ebrahim ),( Magda M. Aly ) 한국식물학회 2004 Journal of Plant Biology Vol.47 No.3

Laboratory and greenhouse experiments were conducted to assess the efficacy of Eucalyptus citriodora, 1pomoea carnea, Cuminum cyminum, Allium sativum and Hyoscyamus muticus leaf extracts, and Streptomyces exfloliatus (S) and Trichoderma harzianum (T) for controlling Botrytis fabae causing chocolate spot disease of faba bean. Laboratory study supported the use of E. citriodora (Ex 1) and I. carnea (Ex 2) extracts than the others for controlling the growth of B. fabae. S+T was the best for inhibiting spore germination followed by Ex 1 +Ex 2 after 8 h of testing, whereas Ex 1 +Ex 2 produced the lowest percent of germination after 16 h. After 4 days, the inhibiting order of the growth of B. fabae was S+T > Ex 1 +Ex 2 > T > Ex 2 > Ex 1= S. Greenhouse experiments showed the highest activities of peroxidase, catalase and pectinase in the infected plants. These activities were markedly reduced in healthy plants and widely changed by the biocontrol treatments. Applying biocontrol agents to the infected plants increased minerals (N, P, K and Mg), and both Chl biosynthesis and the photosynthetic activity, which in turn led to accumulation of metabolites. This served the plant to resist the detrimental effects of B. fabae on the plant growth and yield. In this concern, the efficiency of test biocontrol agents seemed to be in the order: T+S > Ex 1 +Ex 2 > T > S > Ex 2 > Ex.

A closer look at the structure and gamma-ray shielding properties of newly designed boro -tellurite glasses reinforced by bismuth (III) oxide

Thabit Hammam Abdurabu,Ismail Abd Khamim,Yusof N.N.,Sayyed M.I.,Mahmoud K.G.,Abdullahi I.,Hashim S. 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.5

This work presents the synthesis and preparation of a new glass system described by the equation of (70- x) B2O3e5TeO2 e20SrCO3e5ZnO exBi2O3, x ¼ 0, 1, 5, 10, and 15 mol. %, using the melt quenching technique at a melting temperature of 1100 C. The photon-shielding characteristics mainly the linear attenuation coefficient (LAC) of the prepared glass samples were evaluated using Monte Carlo (MC) simulation N-particle transport code (MCNP-5) at gamma-ray energy extended from 59 keV to 1408 keV emitted by the radioisotopes Am-241, Ba-133, Cs-137, Co-60, Na-22, and Eu-152. Furthermore, we observed that the Bi2O3 content of the glasses had a significantly stronger impact on the LAC at 59 and 356 keV. The study of the lead equivalent thickness shows that the performance of fabricated glass sample with 15 mol.% of Bi2O3 is four times less than the performance of pure lead at low gamma photon energy while it is enhanced and became two times lower the perforce of pure lead at high energy. Therefore, the fabricated glasses special sample with 15 mol.% of Bi2O3 has good shielding properties in low, intermediate, and high energy intervals

Experimental assessment for the photon shielding features of silicone rubber reinforced by tellurium borate oxides

M. Elsafi,Heba jamal ALasali,Aljawhara H. Almuqrin,K.G. Mahmoud,M.I. Sayyed Korean Nuclear Society 2023 Nuclear Engineering and Technology Vol.55 No.6

In the present study, six silicone rubber doped by tellurium borate oxides were fabricated using the casting method. The densities of the fabricated silicon rubber-doped by tellurium borate oxides samples were measured using the Archimedes Method. Moreover, the linear attenuation coefficient of silicone rubber doped tellurium borate oxides samples was evaluated experimentally using the hyper pure germanium, and the recorded linear attenuation coefficient values were affirmed using the theoretical Phy-X program. The experimental measurements were performed using the narrow beam transmission method with radioactive isotopes Am-241, Cs-137, and Co-60 with energies of 59, 661, 1173, and 1332 keV. The linear attenuation coefficient values showed an enhancement by 4.73 times, 1.20 time, 1.17, time, and 1.17 time, respectively at gamma photon energies of 59, 661, 1173, and 1332 keV, when the TeO₂ concentration increased in the fabricated composites from 0 to 50 wt%. The enhancement of the linear attenuation coefficient values has a positive effect on the transmission rate values where the half-value thickness and transmission rate were decreased accompanied by an increase in the RPE.

Anti-cancer Effect of Hyoscyamus muticus Extract via Its Activation of Fas/FasL-ASK1-p38 Pathway

Amer Ali Abd El-Hafeez,Hala Mohamed M. Marzouk,Mohamed A. A. Abdelhamid,Hazim O. Khalifa,Tamer H. A. Hasanin,Ahmed G. K. Habib,Fatma Mahmoud Abdelwahed,Fatma M. Barakat,Eslam M. Bastawy,Eman M. B. Abd 한국생물공학회 2022 Biotechnology and Bioprocess Engineering Vol.27 No.5

Hyoscyamus muticus L. is a traditional medicine used as antispasmodic and sedative. Herein, we aimed to determine the phytochemical constituents and for the first time its anti-cancer activities. The phytochemical constituents of the different extracts were evaluated by calorimetric methods. The anti-cancer activities of the extracts were tested against leukemia, breast, renal, and prostate cancers cell lines. 4, 6-Diamidino-2-phenylindole (DAPI) staining, flow cytometric analysis, knockdown of ASK1, and reactive oxygen species (ROS) production were evaluated to clarify the mechanism of action. Phytochemical screening confirmed the presence of wide range of phytoconstituents. Hyoscyamus muticus methanolic extracts (HMME) showed the highest anti-cancer activities against leukemia, breast, renal, and prostate cancers as compared to ethanol and aqueous extracts. Specifically, HMME exerted cytotoxic effect against the MDA-MB-231 and MDA-MB-468 triple-negative breast cancer (TNBC) cell lines with IC50 values of 8.75 and 7.25 μg/mL, respectively. Mechanistically, DAPI staining and flow cytometric analysis revealed that HMME induces apoptosis via the death receptor, FAS, but not the mitochondrial pathway. Moreover, ASK1 and p38 were rapidly activated in response to HMME, and knockdown of ASK1 by a small interference of RNA specific to Ask1 attenuated p38 and caspase-3 activation and suppressed apoptosis, implying that HMME-induced apoptosis relies on the ASK1-p38-caspase-3 pathway. Furthermore, we confirmed that cellular ROS generation was a critical mediator in HMME-induced apoptosis because the ROSscavenger N-acetyl cysteine significantly decreased the phosphorylation of ASK1 and HMME-induced apoptosis. Our results confirmed HMME cytotoxic effects in TNBCs via ROS-dependent activation of the Fas/FasL-ASK1-p38 axis.