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Edema and hematoma after local anesthesia via posterior superior alveolar nerve block: a case report
Aline Louise Nascimento Marques,Sidney R. Figueroba,Marco Antonio Tridapalli Mafra,Francisco Carlos Groppo 대한치과마취과학회 2022 Journal of Dental Anesthesia and Pain Medicine Vol.22 No.3
Although rare, complications can occur with anesthetic procedures. The posterior superior alveolar nerve (PSAN) block anesthetic technique has a high success rate, but positive aspiration can cause bruising, transient diplopia, blurred vision, and temporary blindness in approximately 3% cases. When edema occurs, it is occasionally massive, especially in the infratemporal fossa, and the resulting hematoma is usually unsightly. A 20-year-old woman presented with massive edema followed by hematoma in the upper right jaw immediately after PSAN block administration, which subsequently spread to the oral mucosa. The patient did not report any complications during the anesthetic procedure. However, after the injection was administered, the patient experienced anesthetic sensations, which rapidly evolved to facial edema. There was mild pain, but without intraoral or extraoral bleeding. The patient was prescribed medicines and instructed to perform contrast therapy. Although hematomas and edema are rare, they are difficult to prevent. The choice of local anesthetic and appropriate application of the anesthetic technique can minimize their occurrence.
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( Marta Esgalhado ),( Milena Barcza Stockler-pinto ),( Ludmila Ferreira Medeiros De Franca Cardozo ),( Cinthia Costa ),( Jorge Eduardo Barboza ),( Denise Mafra ) 대한신장학회 2015 Kidney Research and Clinical Practice Vol.34 No.1
Background: Oxidative stress and in.ammation are common .ndings in chronic kidney disease (CKD) patients, and they are directly related to the increased risk of developing cardiovascular disease, which is the major cause of death in these patients, particularly for those undergoing hemodialysis (HD). Strength physical exercise is a new therapeutic approach to reduce these complications in CKD patients. Following this, the purpose of this study was to assess the effect of acute intradialytic strength physical exercise on oxidative stress and in.ammatory responses in HD patients. Methods: Sixteen HD patients were studied (11 women; 44.4714.6 years; body mass index 23.374.9 kg/m2; 61.6743.1 months of dialysis) and served as their own controls. Acute (single session) intradialytic physical exercise were performed at 60% of the onerepetition maximum test for three sets of 10 repetitions for four exercise categories in both lower limbs during 30 minutes. Blood samples were collected on two different days at exactly the same time (30 minutes and 60 minutes after initiating the dialysis-with and without exercise). Antioxidant enzymes activity [superoxide dismutase (SOD), catalase, and glutathione peroxidase], lipid peroxidation marker levels (malondialdehyde), and in.ammatory marker levels (high-sensitivity C-reactive protein) were determined. Results: SOD plasma levels were signi.cantly reduced after acute physical exercise from 244.8740.7 U/mL to 222.4728.9 U/mL (P¼0.03) and, by contrast, increased on the day without exercise (218.2726.5 U/mL to 239.4738.6 U/mL, P¼0.02). There was no alteration in plasma catalase, glutathione peroxidase, malondialdehyde, or highsensitivity C-reactive protein levels in on either day (with or without exercise). Additionally, there was no association between these markers and clinical, anthropometric, or biochemical parameters. Conclusion: These data suggest that acute intradialytic strength physical exercise was unable to reduce oxidative stress and in.ammation, and in addition, it seems to reduce plasma SOD levels, which could exacerbate the oxidative stress in HD patients. Copyright & 2015. The Korean Society of Nephrology. Published by Elsevier. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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Cinnamon: an aromatic condiment applicable to chronic kidney disease
Moreira Laís de Souza Gouveia,Brum Isabela de Souza da Costa,de Vargas Reis Drielly C. M.,Trugilho Liana,Chermut Tuany R.,Esgalhado Marta,Cardozo Ludmila F. M. F.,Stenvinkel Peter,Shiels Paul G.,Mafra 대한신장학회 2023 Kidney Research and Clinical Practice Vol.42 No.1
Cinnamon, a member of the Lauraceae family, has been widely used as a spice and traditional herbal medicine for centuries and hasshown beneficial effects in cardiovascular disease, obesity, and diabetes. However, its effectiveness as a therapeutic intervention forchronic kidney disease (CKD) remains unproven. The bioactive compounds within cinnamon, such as cinnamaldehyde, cinnamicacid, and cinnamate, can mitigate oxidative stress, inflammation, hyperglycemia, gut dysbiosis, and dyslipidemia, which are commoncomplications in patients with CKD. In this narrative review, we assess the mechanisms by which cinnamon may alleviate complicationsobserved in CKD and the possible role of this spice as an additional nutritional strategy for this patient group.
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