[3rd Prize] 마챠도 앤 실베티 어소시에이트+공간종합건축사사무소

루돌프 마챠도(Rodolfo Machado),죠지 실베티(Jorge Silvetti),이상림(Lee, Sang-lim) 현대건축사 2004 월간 CONCEPT Vol.- No.68

The role of interfacial elasticity on the rheological behavior of polymer blends

Jorge M. Silva,Ana V. Machado,Paula Moldenaers,João M. Maia 한국유변학회 2010 Korea-Australia rheology journal Vol.22 No.1

In this work, the influence of interfacial modification on the rheological behavior of polymer blends was investigated. First, commercial blends of polyamide-6 and ethylene-propylene copolymer, PA6/EPM, noncompatibilized and compatibilized with EPM grafted with maleic anhydride, with high viscosity and elasticity ratios were studied. The observation of the morphology frozen during extension tests seemed to indicate that the droplets of the highly compatibilized blends are slightly deformed unlike those of the noncompatibilized ones. Stress relaxation experiments, both in shear and extension, showed that the introduction of the compatibilizer leads to the appearance of a second very long relaxation mechanism, the question then being what is its cause. In order to better understand the relative importance of relaxation of the droplets and relaxation of the interfaces in this kind of compatibilized blends, model high viscosity ratio blends of optically transparent materials, in this case poly(methylmethacrylate), PMMA, polystyrene, PS,and oxazoline-modified polystyrene, PSOX were prepared. This allows Small Angle Light Scattering (SALS) to be used in dilute blends to complement the rheometrical characterization and thus evaluate the deformation of the droplets in transient shear flows. In these blends there is also an additional longer relaxation time present but no changes in the morphology can be readily observed. In addition, the blend with functionalized PS shows a droplet deformation in the vorticity direction, which is an indication of an increase in the elasticity of the interface. Thus, our findings seem to indicate that the main factor behind the increase in relaxation time stress relaxation at and in the interfaces and not droplet deformation and recovery. The role of the elasticity of the interface became quite clear when PP/EVOH blends, non-compatibilized and compatibilized with Na+ were tested. In this case the elasticity of the interface is negligible and it was observed that the compatibilization does not alter significantly the relaxation behavior after a step deformation.

Persistent pain after successful endodontic treatment in a patient with Wegener’s granulomatosis: a case report

Machado Ricardo,Pereira Jorge Aleixo,Vitali Filipe Colombo,Bolan Michele,Rivero Elena Riet Correa 대한치과보존학회 2022 Restorative Dentistry & Endodontics Vol.47 No.3

Wegener’s granulomatosis (WG) is a condition with immune-mediated pathogenesis that can present oral manifestations. This report describes the case of a patient diagnosed with WG 14 years previously, who was affected by persistent pain of non-odontogenic origin after successful endodontic treatment. A 39-year-old woman with WG was diagnosed with pulp necrosis and apical periodontitis of teeth #31, #32, and #41, after evaluation through a clinical examination and cone-beam computed tomography (CBCT). At the first appointment, these teeth were subjected to conventional endodontic treatment. At 6- and 12-month follow-up visits, the patient complained of persistent pain associated with the endodontically treated teeth (mainly in tooth #31), despite complete remission of the periapical lesions shown by radiographic and CBCT exams proving the effectiveness of the endodontic treatments, thus indicating a probable diagnostic of persistent pain of non-odontogenic nature. After the surgical procedure was performed to curette the lesion and section 3 mm of the apical third of tooth #31, the histopathological analysis suggested that the painful condition was likely associated with the patient's systemic condition. Based on clinical, radiographic, and histopathological findings, this unusual case report suggests that WG may be related to non-odontogenic persistent pain after successful endodontic treatments.

A Review on Acupuncture Efficiency in Human Polycystic Ovary/Ovarian Syndrome

Oliveira Natália M. de,Machado Jorge,Lopes Lara,Criado Maria Begoña,Oliveira Natália M. de 대한약침학회 2023 Journal of pharmacopuncture Vol.26 No.2

Objectives: Human Polycystic Ovary/Ovarian Syndrome (PCOS), a frequent endocrine pathophysiology among women of fertile age, is associated with woman’s lifespan endocrine, metabolic and psychological implications. Long-term usage side effects of allopathic strategies and their low efficacy made complementary medicine treatments a relevant subject for these patients. The main aim of this work is to review the efficiency of the acupuncture treatment reported in the latest studies on literature regarding PCOS patients. Methods: A comprehensive literature search, in English language, about the use of acupuncture on the management of PCOS, was conducted in October 2020 using EBSCO, Cochrane, PubMed, Medline, Embase, databases for randomised and non-randomised controlled trials between 2015 and 2020 (09/2015-10/2020), following the PRISMA protocol. Results: This research led us to an analysis, according to PICOS, of six final papers selected among 178 in total. The articles addressed distinct aspects of the PCOS condition, diverse acupuncture techniques and different main and secondary outcomes in agreement to the respective main objective. According to this review, acupuncture seems to be useful for the treatment of this debilitating and chronic health condition which affects millions of women worldwide, many of them part of the workforce in their community. Conclusion: Despite of the display of these positive results addressing acupuncture treatments to manage PCOS major symptoms - whether they are reproductive, metabolic, or mental health features - more research is urgent. Randomized, double blinded controlled trials with improved quality design and following STRICTA and/or CONSORT recommendations are necessary to engage acupuncture as a standardized and scientific validated technique in PCOS condition.

A review of properties, nutritional and pharmaceutical applications of Moringa oleifera: integrative approach on conventional and traditional Asian medicine

Diana Meireles,João Gomes,Lara Lopes,Mariana Hinzmann,Jorge Machado 경희대학교 융합한의과학연구소 2020 Oriental Pharmacy and Experimental Medicine Vol.20 No.4

Moringa oleifera L. from the Moringaceae family is a perennial tree widely cultivated in many tropic regions and easily grown even in adverse conditions. M. oleifera is also known as the miracle tree, which for centuries has been indicated for traditional medicine. With no reports of side effects, in doses achievable by ingestion, different parts of M. oleifera is used to treat several conditions, such as malnutrition, diabetes, blindness, anemia, hypertension, stress, depression, skin, arthritis, joints and kidney stones disorders. This plant also showed capacity of helping in maintenance of the cardiovascular system health, blood-glucose levels and providing anti-oxidant, anti-inflammatory and anti-cancer activity as well as the regulation of urinary tract and lactation in nursing women. The seed and leaves powder has water purification properties through flocculation. It also supplements the food in the human diet and in the fortification of livestock feed, especially in developing countries. So, M. oleifera properties have also been applied to cosmetic and byproducts industries due to the high nutritive and protective properties of its seed oil. According to the holistic or traditional medicine, M. oleifera has very relevant therapeutic properties and applications depending on the constitution, somatic and psychological needs of patients. It is usually referred as a natural product that can treat different physical and psychological health aspects, offering an energetic action and structural rebuilder of the body and promoting emotions of highly positive attitudes towards life. The high and specific immunological potential of M. oleifera leads us to suggest an in-depth study to assess the hypothesis of conferring a supportive effect against Covid-19 disease.