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        Antioxidant and hepatoprotective action of the crude ethanolic extract of theflowering top of Rosa damascena

        MA Alam,MAB Nyeem,MA Awal,M Mostofa,MS Alam,N Subhan,M MostafizurRahman 경희대학교 융합한의과학연구소 2008 Oriental Pharmacy and Experimental Medicine Vol.8 No.2

        The hepatoprotective activity of the alcoholic extract of Rosa damascena was studied against paracetamol induced acute hepatotoxicity in rats. Liver damage was assessed by estimating serum enzyme activities of aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase and histopathology of liver tissue. Pre- and post-treatment with ethanolic extracts showed a dose-dependent reduction of paracetamol induced elevated serum levels of enzyme activity. The mechanism underlying the protective effects was assayed in vitro and the R. damascena extracts displayed dosedependent free radical activity using DPPH (IC50 = 162.525 μg/ml) and TBA method. The hepatoprotective action was confirmed by histopathological observation. The ethanolic extracts reversed paracetamol induced liver injury. These results suggest that the hepatoprotective effects of R. damascena extracts are related to its antioxidative activity. The hepatoprotective activity of the alcoholic extract of Rosa damascena was studied against paracetamol induced acute hepatotoxicity in rats. Liver damage was assessed by estimating serum enzyme activities of aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase and histopathology of liver tissue. Pre- and post-treatment with ethanolic extracts showed a dose-dependent reduction of paracetamol induced elevated serum levels of enzyme activity. The mechanism underlying the protective effects was assayed in vitro and the R. damascena extracts displayed dosedependent free radical activity using DPPH (IC50 = 162.525 μg/ml) and TBA method. The hepatoprotective action was confirmed by histopathological observation. The ethanolic extracts reversed paracetamol induced liver injury. These results suggest that the hepatoprotective effects of R. damascena extracts are related to its antioxidative activity.

      • Antioxidant and hepatoprotective action of the crude ethanolic extract of the flowering top of Rosa damascena

        Alam, MA,Nyeem, MAB,Awal, MA,Mostofa, M,Alam, MS,Subhan, N,Rahman, M Mostafizur Kyung Hee Oriental Medicine Research Center 2008 Oriental pharmacy and experimental medicine Vol.8 No.2

        The hepatoprotective activity of the alcoholic extract of Rosa damascena was studied against paracetamol induced acute hepatotoxicity in rats. Liver damage was assessed by estimating serum enzyme activities of aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase and histopathology of liver tissue. Pre- and post-treatment with ethanolic extracts showed a dose-dependent reduction of paracetamol induced elevated serum levels of enzyme activity. The mechanism underlying the protective effects was assayed in vitro and the R. damascena extracts displayed dosedependent free radical activity using DPPH ($IC_{50}=162.525\;{\mu}g/ml$) and TBA method. The hepatoprotective action was confirmed by histopathological observation. The ethanolic extracts reversed paracetamol induced liver injury. These results suggest that the hepatoprotective effects of R. damascena extracts are related to its antioxidative activity.

      • Effectiveness of some selected insecticides and botanicals against okra shoot and fruit borer

        Mazed, MA,Alam, MZ,Miah, MRU,Hossain, MS,Awal, MA Bangladesh Journals Online 2017 Bangladesh journal of agricultural research Vol.42 No.2

        <P>An experiment was conducted to evaluate the effectiveness of some selected insecticides and botanicals against okra shoot and fruit borer Earias vittella F. under field conditions. The insecticides tested were Relothrin 10EC @ 1ml l-1, Marshal 20EC @ 2ml l-1and Riva 2.5 EC @ ml l-1; and the botanicals were NSKE @ 50g l-1, Neem leaf extract @ 100g l-1 and Bishkatali leaf extract @ 100g l-1. An additional treatment of Mechanical control (hand picking) and an untreated control were maintained in the experiment for comparison. All treatments were applied at 15 days interval. Shoot infestation was the lowest in Marshal 20EC treated plot (4.34% at pre-fruiting and 3.55% at fruiting stage) and the highest was in untreated control plot (21.4%). The lowest fruit infestation by okra shoot and fruit borer was obtained with Marshal 20EC (5.07% n/n and 3.65% w/w) followed by Relothrin 10EC (5.43% n/n and 4.27% w/w) and the highest infestation was observed under untreated control plot (19.67% n/n and 19.81% w/w). The reduction of fruit infestation over untreated control ranged from 56.93-81.55% by number and 43.47-74.22% by weight. The highest marketable yield (10.46 t ha-1) was obtained in Marshal 20EC treated plot followed by in Relothrin 10EC 10.30 t ha-1 with the maximum benefit cost ratio (BCR) 6.72.Bangladesh J. Agril. Res. 42(2): 353-362, June 2017</P>

      • Thiocyanate functionalized ionic liquid electrolyte for photoelectrochemical study of cadmium selenide pebbles

        Pawar, S.A.,Patil, D.S.,Patil, S.K.,Awale, D.V.,Devan, R.S.,Ma, Y.R.,Kolekar, S.S.,Kim, J.H.,Patil, P.S. Pergamon Press 2014 ELECTROCHIMICA ACTA Vol.148 No.-

        A thiocyanate functionalized ionic liquid based electrolyte is developed for the application in CdSe thin film solar cell. An aqueous solvent consisting of polysulfide and thiocyanate functionalized IL has been found as the optimum solvent for preparing the liquid electrolytes. This solvent ratio appears to give higher cell efficiency compared to pure aqueous polysulfide electrolyte. Polysulfide and thiocyanate functionalized IL give rise to a good redox couple in the electrolyte for photoelectrochemical performance. The CdSe photoanode used for solar cell study has been synthesized by a simple and cost-effective one-step, one-pot chemical bath deposition method onto the F: SnO<SUB>2</SUB> substrates. The as-deposited films were annealed at temperatures 100, 200, 300 and 400<SUP>o</SUP>C, respectively for 1h in ambient air. The maximum current density of 3.55mA/cm<SUP>2</SUP> for the sample annealed at 300<SUP>o</SUP>C is observed in the polysulfide electrolyte with the power conversion efficiency 0.76%. Addition of thiocyanate functionalized IL in polysulfide produced the highest current density of 4.93mA/cm<SUP>2</SUP> with the two fold increase in the power conversion efficiency up to 1.32%.

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