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      • The Underutilization of Lifestyle Modifications in Primary Care Medicine

        Jean-Marc Lucas(Jean-Marc Lucas ),Karl F. Kozlowski(Karl F. Kozlowski ) 사피엔시아 2019 Exercise Medicine Vol.3 No.-

        Chronic disease accounts for the majority of deaths in the United States and is often attributed to obesity. A sedentary lifestyle and poor nutrition are primary contributing factors to the development of obesity and thus chronic disease. Primary care providers are optimally positioned to prescribe exercise and nutrition (lifestyle medicine) as a treatment for chronic disease. Unfortunately, this opportunity seems to be regularly lost. Primary care providers often rely too heavily on weight loss pharmaceuticals and bariatric surgeries to treat obesity. This treatment approach however also does little to prevent and treat the accumulation of chronic diseases. The purpose of this review was to evaluate the efficacy of conventional medical weight loss treatments and determine why primary care providers may not prescribe exercise and nutrition more frequently. Our findings suggest that some primary care providers may be uncomfortable prescribing lifestyle medicine as they receive little formal education in this field. In conclusion, prescription of exercise and nutrition by primary care providers may elicit greater long-term weight loss than current medical weight management practices. Medical management is most likely effective when combined with lifestyle medicine. We propose that primary care providers be better trained in lifestyle medicine through their formal and clinical education. Rates of chronic disease accumulation may potentially decrease if providers prescribe lifestyle medical treatments more frequently.

      • SCIESCOPUSKCI등재

        BERTRAND CURVES IN NON-FLAT 3-DIMENSIONAL (RIEMANNIAN OR LORENTZIAN) SPACE FORMS

        Lucas, Pascual,Ortega-Yagues, Jose Antonio Korean Mathematical Society 2013 대한수학회보 Vol.50 No.4

        Let $\mathbb{M}^3_q(c)$ denote the 3-dimensional space form of index $q=0,1$, and constant curvature $c{\neq}0$. A curve ${\alpha}$ immersed in $\mathbb{M}^3_q(c)$ is said to be a Bertrand curve if there exists another curve ${\beta}$ and a one-to-one correspondence between ${\alpha}$ and ${\beta}$ such that both curves have common principal normal geodesics at corresponding points. We obtain characterizations for both the cases of non-null curves and null curves. For non-null curves our theorem formally agrees with the classical one: non-null Bertrand curves in $\mathbb{M}^3_q(c)$ correspond with curves for which there exist two constants ${\lambda}{\neq}0$ and ${\mu}$ such that ${\lambda}{\kappa}+{\mu}{\tau}=1$, where ${\kappa}$ and ${\tau}$ stand for the curvature and torsion of the curve. As a consequence, non-null helices in $\mathbb{M}^3_q(c)$ are the only twisted curves in $\mathbb{M}^3_q(c)$ having infinite non-null Bertrand conjugate curves. In the case of null curves in the 3-dimensional Lorentzian space forms, we show that a null curve is a Bertrand curve if and only if it has non-zero constant second Frenet curvature. In the particular case where null curves are parametrized by the pseudo-arc length parameter, null helices are the only null Bertrand curves.

      • Building Relatedness Through Hashtags: Social Influence and Motivation Within Social Media-Based Online Discussion Forums

        ( Lucas John Jensen ) 한국교육공학회 2016 한국교육공학회 학술대회발표자료집 Vol.2016 No.1

        In the last two decades, the mainstream growth of the Internet has led to transformative change in education, particularly higher education, as the Internet has provided new opportunities for learning online and at a distance (Allen & Seaman, 2010, Shea & Bidjerano, 2010). Commensurate with this has been a rise in the sphere of online activity known as social media - networks of users tied together via Web 2.0-based applications that offer users an opportunity to generate and share content of their own (Kaplan & Haenlein, 2010). A recent development in the world of social media is the introduction of so-called "hashtags," represented symbolically by the "#" or "pound sign" symbol, joining use together, even if they don``t know each other (Ebner, Beham, Costa, & Reinhardt, 2009, Page, 2012). Easy to create, hashtags have become a unique way to experience global events, have political debates, or meet people with similar interests. For some time, online discussion forums have been a preferred pedagogical method of generating and facilitating discussion in online education and classrooms with online components (Mazzolini & Maddison, 2003, Rossman, 1999). Online discussion forums are typically administered through the built-in tools of a Learning Management System (LMS). Although LMSs offer basic tools for class instruction and management, there is debate as to the limits of their pedagogical value (Hong, 2008, Martindale & Wiley, 2004). The pedagogical concept of Personal Learning Environments (PLEs) challenges the dominance of LMS usage in online courses, bringing a student-centered and bottom-up perspective to online education. The thinking behind PLEs is that instruction should be situated in an environment more congruent with the learners`` typical technology usage for their personal lives, such as social media (Attwell, 2007). The purpose of this presentation is to share the research results of a study investigating the motivation of student``s participation in an online discussion forum when moved from an LMS to a class Twitter hashtag group. Twitter activity was analyzed, and respondents were surveyed on their intrinsic motivation in online discussions, social influences on their social media choice, and if their previous experience with social media affected motivation.

      • SCIESCOPUSKCI등재

        SLANT HELICES IN THE THREE-DIMENSIONAL SPHERE

        Lucas, Pascual,Ortega-Yagues, Jose Antonio Korean Mathematical Society 2017 대한수학회지 Vol.54 No.4

        A curve ${\gamma}$ immersed in the three-dimensional sphere ${\mathbb{S}}^3$ is said to be a slant helix if there exists a Killing vector field V(s) with constant length along ${\gamma}$ and such that the angle between V and the principal normal is constant along ${\gamma}$. In this paper we characterize slant helices in ${\mathbb{S}}^3$ by means of a differential equation in the curvature ${\kappa}$ and the torsion ${\tau}$ of the curve. We define a helix surface in ${\mathbb{S}}^3$ and give a method to construct any helix surface. This method is based on the Kitagawa representation of flat surfaces in ${\mathbb{S}}^3$. Finally, we obtain a geometric approach to the problem of solving natural equations for slant helices in the three-dimensional sphere. We prove that the slant helices in ${\mathbb{S}}^3$ are exactly the geodesics of helix surfaces.

      • SCIESCOPUSKCI등재

        HYPERSURFACES IN 𝕊<sup>4</sup> THAT ARE OF L<sub>k</sub>-2-TYPE

        Lucas, Pascual,Ramirez-Ospina, Hector-Fabian Korean Mathematical Society 2016 대한수학회보 Vol.53 No.3

        In this paper we begin the study of $L_k$-2-type hypersurfaces of a hypersphere ${\mathbb{S}}^{n+1}{\subset}{\mathbb{R}}^{n+2}$ for $k{\geq}1$ Let ${\psi}:M^3{\rightarrow}{\mathbb{S}}^4$ be an orientable $H_k$-hypersurface, which is not an open portion of a hypersphere. Then $M^3$ is of $L_k$-2-type if and only if $M^3$ is a Clifford tori ${\mathbb{S}}^1(r_1){\times}{\mathbb{S}}^2(r_2)$, $r^2_1+r^2_2=1$, for appropriate radii, or a tube $T^r(V^2)$ of appropriate constant radius r around the Veronese embedding of the real projective plane ${\mathbb{R}}P^2({\sqrt{3}})$.

      • KCI등재후보

        Do changes in inflammatory markers predict hepatocellular carcinoma recurrence and survival after liver transplantation?

        Lucas Jose Caram,Francisco Calderon,Esteban Masino,Victoria Ardiles,Ezequiel Mauro,Leila Haddad,Juan Pekolj,Jimena Vicens,Adrian Gadano,Eduardo de Santibanes,Martin de Santibanes 한국간담췌외과학회 2022 Annals of hepato-biliary-pancreatic surgery Vol.26 No.1

        Backgrounds/Aims: The role of inflammation in malignant cell proliferation has been well described. High values of platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR) as markers of systemic inflammation have shown associations with unfavorable long-term outcomes. The purpose of this study was to determine values of NLR and PLR evaluated prior to and after surgery and their associations with mortality and recurrence rates of liver transplant patients with hepatocellular carcinoma (HCC). Methods: A total of 105 patients with HCC who underwent orthotopic liver transplantation (OLT) were retrospectively reviewed. NLR and PLR values were obtained from complete blood counts prior to and after surgery. Overall survival (OS) and recurrence-free survival (RFS) in relation with delta NLR and PLR were estimated. Results: Serum alpha-fetoprotein levels > 100 ng/mL (p = 0.014) and lymphovascular emboli in the specimen (p = 0.048) were identified to be significant predictors of RFS. Child-Pugh score (p = 0.016) was found to be an independent factor associated with poorer OS. An increasing delta PLR was associated with worse RFS, although it showed no significant association with OS. Conclusions: The analysis of PLR as a continuous variable may predict recurrence outcomes in patients undergoing OLT for HCC. It is more representative than isolated values.

      • KCI등재

        The effect of repeated surface treatment of zirconia on its bond strength to resin cement

        Lucas Campagnaro Maciel,Marina Amaral,Daher Antonio Queiroz,Kusai Baroudi,Laís Regiane Silva-Concílio 대한치과보철학회 2020 The Journal of Advanced Prosthodontics Vol.12 No.5

        PURPOSE. The aim of this study is to evaluate the influence of repeated surface treatments on wettability and surface roughness for zirconia surface and bond strength of zirconia-based ceramics to resin cement. MATERIALS AND METHODS. Seventy blocks (10 × 10 × 3 mm) of zirconia-based ceramics were fabricated and divided into two groups according to the surface treatments: (A) 110 μm Al2O3 airborne-particle abrasion and (R) 110 μm silica modified Al2O3 airborne-particle abrasion. At stage 2, each group was subdivided into 5 groups according to the surface retreatments: (a) 110 μm Al2O3 airborne-particle abrasion, (r) 110 μm silica modified Al2O3 airborne-particle abrasion, (D) diamond bur, (Da) diamond bur + 110 μm Al2O3 airborne-particle abrasion, and (Dr) diamond bur + 110 μm silica modified Al2O3 airborne-particle abrasion. Cylinders of self-adhesive resin cement were cemented onto each treated ceramic surface and subjected to micro-shear bond strength test. Additional specimens were prepared for roughness and wettability analyses. The data were subjected to t-test and One-way ANOVA followed by Tukey’s post hoc test (α=.05). RESULTS. At stage 1, group R presented higher bond strength values than group A (P=.000). There was a statistically significant increase of bond strength at stage 2 for group A (P=.003). The diamond bur influenced the surface roughness, increasing the values (P=.023). Group R provided better wettability. Regardless of the applied surface treatment, most of failures were adhesive. CONCLUSION. The combination of application and reapplication of Rocatec Plus showed the best results of bond strength. Surface retreatment and recementation might be an indicated clinical strategy.

      • KCI등재

        Different organic components on silica hybrid matrices modulate the lipase inhibition by the glycerol formed in continuous transesterification reactions

        Lucas S. Martin,Annie Ceron,Pedro C. Oliveira,Gisella M. Zanin,Heizir F. de Castro 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.62 No.-

        Silica hybrid materials, functionalized via incorporation of three organic components: β-cyclodextrin (βCD), carboxymethyl-cellulose (CMC) and hydroxyethyl-cellulose (HEC) were synthesized by the sol–gel technique and results were compared to a well-defined matrix (silica–polyvinyl alcohol–SiO2–PVA) with respect to immobilizing Burkholderia cepacia lipase. The main objective was set to select organic components that can replace the PVA to obtain a hybrid composite with greater hydrophobic character, without compromising the remarkable features of SiO2–PVA. All the three selected compounds allowed obtaining matrices that presented similar textural and morphological properties and gave high activity (1451–1661 U g−1) and thermal stability (t1/2 > 70 h) upon immobilization. Regarding glycerol affinity, all matrices had lower ability than SiO2–PVA to adsorb glycerol, with the SiO2–βCD matrix showing the lowest affinity due to the cyclic structure of the βCD. Transesterification reactions of palm kernel oil with ethanol mediated by B. cepacia immobilized on SiO2–βCD performed in a packed bed reactor under continuous flow confirmed the efficiency of the SiO2–βCD matrix in increasing the operational stability of system, revealing a half-life (t1/2 = 1040 h), 2.5 times greater than that achieved in the same system using lipase immobilized on SiO2–PVA (t1/2 = 430 h).

      • SCOPUSKCI등재

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