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      • Eu<sup>3+</sup> doped lutetium molybdenum oxides: Synthesis, optical properties, thermal behavior, and LED packaging

        Cao, Chunyan,Xie, Along,Zhou, Tianliang,Zhong, Haichang,Lu, Xiangjun,Xie, An,Noh, Hyeon Mi,Jeong, Jung Hyun Elsevier 2020 Journal of luminescence Vol.217 No.-

        <P><B>Abstract</B></P> <P>Some lutetium molybdenum oxides were synthesized through a solid-state reaction method. By adjusting the molar ratios of raw materials of Lu<SUB>2</SUB>O<SUB>3</SUB> (Eu<SUB>2</SUB>O<SUB>3</SUB>) to MoO<SUB>3</SUB>, Eu<SUP>3+</SUP> doped lutetium molybdenum oxides Lu<SUB>2</SUB>MoO<SUB>6</SUB>, Lu<SUB>2</SUB>Mo<SUB>2</SUB>O<SUB>9</SUB>, Lu<SUB>2</SUB>(MoO<SUB>4</SUB>)<SUB>3</SUB>, and Lu<SUB>6</SUB>MoO<SUB>12</SUB> were obtained. The materials were characterized by X-ray diffraction (XRD) patterns, scanning electron microscope (SEM) images, energy-dispersive spectra (EDS), diffuse reflection (DR) spectra, photoluminescence (PL) excitation and emission spectra, luminescence decay curves, and temperature dependent integrated emission spectra. Enhanced excitation and emission spectra were recorded at high temperatures. Possible energy transfer processes were proposed to explain the excitation and emission spectra. By combining some phosphors with near ultraviolet (NUV) chips, the obtained light emitting diodes (LEDs) gave red light under forward bias current. The results suggest that the obtained Eu<SUP>3+</SUP> doped lutetium molybdenum oxides have potential applications in phosphor converted based NUV LEDs.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Eu<SUP>3+</SUP> doped Lu<SUB>2</SUB>MoO<SUB>6</SUB>, Lu<SUB>2</SUB>Mo<SUB>2</SUB>O<SUB>9</SUB>, Lu<SUB>2</SUB>(MoO<SUB>4</SUB>)<SUB>3</SUB>, and Lu<SUB>6</SUB>MoO<SUB>12</SUB> were obtained. </LI> <LI> The materials present different structures, morphologies, optical properties, and luminescece decay behaviors. </LI> <LI> Eu<SUP>3+</SUP> concentration dependent optical properties in Lu<SUB>2</SUB>MoO<SUB>6</SUB> were researched. </LI> <LI> Enhanced excitation and emission spectra were recorded under high temperatures in some materials. </LI> <LI> Red LEDs were obtained by packaging phosphors to NUV LED chips. </LI> </UL> </P>

      • KCI등재

        중국 국영기업의 인적자원개발 실태에 관한 사례연구

        Zhou Lu,박윤희(Yoonhee Park) 중앙대학교 한국인적자원개발전략연구소 2020 역량개발학습연구 Vol.15 No.4

        중국에서는 1980년대부터 인적자원개발(HRD: Human Resource Development)이 확산되면서 급속도로 성장하였다. 중국에서 HRD의 발전은 국영기업도 긍정적인 영향을 미쳐 국영기업의 발전에 기여하였다. 그러나 지금까지 중국 내 국영기업(State-Owned Enterprises)에서 HRD가 어떻게실시되고 있는지에 대한 연구는 많이 이루어지지 않았다. 따라서 이 논문의 목적은 중국에서 업종별(음식, 자동차, 기계, 위성통신, 건설)로 5개의 국영기업을 선정하여 사례연구를 실시함으로써HRD 운영 실태를 파악하는 것이다. 보다 구체적으로 이 연구에서는 세 가지의 연구문제를 설정하였다. 첫째, 중국의 국영기업에서 훈련 및 개발은 어떻게 이루어지고 있는가? 둘째, 중국의 국영기업에서 경력개발은 어떻게 이루어지고 있는가? 셋째, 중국의 국영기업에서 조직개발은 어떻게이루어지고 있는가? 사례연구 결과, 훈련 및 개발 측면에서는 국영기업에서 교육훈련을 실시한 후자격증을 발급하고 있는데, 이러한 자격증은 구성원들의 학습 의욕을 촉진하고 있는 것으로 나타났다. 그리고 기업과 대학 간의 교육훈련 협력도 빈번하게 이루어지고 있었다. 그리고 중국 국영기업의 인사시스템 특성은 직원들의 경력개발을 저해하는 것으로 나타났다. 즉, 국영기업에서는임용제를 시행하기 때문에 공정한 경쟁 대신 상급자가 직접 직무 담당자를 선정하고 있어 경력개발이 활성화되지 않은 실정이다. 또 국영기업의 조직개발은 체계적으로 이루어지지 않았다. 예를들면, 국영기업에서는 직원 간 소통을 촉진하거나 조직변화를 도모하기 위해 조직개발을 위한 여러 가지 활동이나 개입을 활용하지 않는 것으로 드러났다. 이러한 연구 결과를 토대로 중국 국영기업에서 HRD의 발전을 위하여 6개의 제안 사항을 제시하였다. 아울러 중국 국영기업의 HRD에대한 실무적 시사점과 향후 연구 방향을 제시하였다. The purpose of this research was to identify the current st atus of HRD (Human Resource Development) by select ing five state-owned enterprises (SOEs) by industry (food, automobile, machinery, satellite communications, and construction) as case studies. More specifically, the study was intended to address three research questions: 1) How is training and development taking place in China s SOEs? 2) Second, how is career development taking place in China s SOEs? 3) Third, how is organizational development t aking place in China s SOEs? This study used the method of a multi-case study to examine the HRD practices of five SOEs from different industries. Case studies show that in terms of training and development, the state-owned enterprises issue certificates after conducting educat ion and training, which promote members willingness to learn. Moreover, cooperation in education and training between companies and universities was frequent. Furthermore, the characteristics of the personnel system of China s state-owned enterprises have been shown to hinder the career development of employees. In addition, the organizational development of state-owned enterprises was not systematically undertaken. The conclusion of this paper reveals six themes of HRD practice status and puts forward six suggestions for HRD in SOEs in China. Based on the results of the study, this study suggest s development strategies for HRD in SOEs, implications of HRD practice in SOEs, and future research directions.

      • KCI등재

        Characteristics and Comparisons of Morphometric Measurements and Computed Tomography Hounsfield Unit Values of C2 Laminae for Translaminar Screw Placement Between Patients With and Without Basilar Invagination

        Lu-Ping Zhou,Jin Shang,Zhi-Gang Zhang,Zhen-Fei Jiang,Hua-Qing Zhang,Chong-Yu Jia,Ren-Jie Zhang,Cai-Liang Shen 대한척추신경외과학회 2022 Neurospine Vol.19 No.4

        Objective: Patients with basilar invagination (BI) had high incidences of vertebral variations and high-riding vertebral artery (HRVA) that might restrict the use of pedicle or pars screw and increase the use of translaminar screw on axis. Here, we conducted a radiographic study to investigate the feasibility of translaminar screws and the bone quality of C2 laminae in patients with BI, which were compared with those without BI as control to provide guidelines for safe placement. Methods: In this study, a total of 410 patients (205 consecutive patients with BI and 205 matched patients without BI) and 820 unilateral laminae of the axis were included at a 1:1 ratio. Comparisons with regard to insertion parameters (laminar length, thickness, angle, and height) for C2 translaminar screw placement and Hounsfield unit (HU) values for the assessment of the appropriate bone mineral density of C2 laminae between BI and control groups were performed. Besides, the subgroup analyses based on the Goel A and B classification of BI, HRVA, atlas occipitalization, and C2/3 assimilation were also carried out. Furthermore, the factors that might affect the insertion parameters and HU values were explored through multiple linear regression analyses. Results: The BI group showed a significantly smaller laminar length, thickness, height, and HU value than the control group, whereas no significant difference was observed regarding the laminar angle. By contrast, the control group showed significantly higher rates of acceptability for unilateral and bilateral translaminar screw fixations than the BI group. Subgroup analyses showed that the classification of Goel A and B, HRVA, atlas occipitalization, and C2/3 assimilation affected the insertion parameters except the HU values. Multiple linear regression indicated that the laminar length was significantly associated with the male gender (B = 0.190, p < 0.001), diagnoses of HRVA (B = -0.109, p < 0.001), Goel A (B = -0.167, p < 0.001), and C2/3 assimilation (B = -0.079, p = 0.029); the laminar thickness was significantly associated with the male gender (B = 0.353, p < 0.001), diagnoses of HRVA (B = -0.430, p < 0.001), Goel B (B = -0.249, p = 0.026), and distance from the top of odontoid to the Chamberlain line (B = -0.025, p = 0.003); laminar HU values were significantly associated with age (B = -2.517, p < 0.001), Goel A (B = -44.205, p < 0.001), Goel B (B = -25.704, p = 0.014), and laminar thickness (B = -11.706, p = 0.001). Conclusion: Patients with BI had narrower and smaller laminae with lower HU values and lower unilateral and bilateral acceptability for translaminar screws than patients without BI. Preoperative 3-dimensional computed tomography (CT) and CT angiography were needed for BI patients.

      • Establishing a Nomogram for Stage IA-IIB Cervical Cancer Patients after Complete Resection

        Zhou, Hang,Li, Xiong,Zhang, Yuan,Jia, Yao,Hu, Ting,Yang, Ru,Huang, Ke-Cheng,Chen, Zhi-Lan,Wang, Shao-Shuai,Tang, Fang-Xu,Zhou, Jin,Chen, Yi-Le,Wu, Li,Han, Xiao-Bing,Lin, Zhong-Qiu,Lu, Xiao-Mei,Xing, H Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.9

        Background: This study aimed to establish a nomogram by combining clinicopathologic factors with overall survival of stage IA-IIB cervical cancer patients after complete resection with pelvic lymphadenectomy. Materials and Methods: This nomogram was based on a retrospective study on 1,563 stage IA-IIB cervical cancer patients who underwent complete resection and lymphadenectomy from 2002 to 2008. The nomogram was constructed based on multivariate analysis using Cox proportional hazard regression. The accuracy and discriminative ability of the nomogram were measured by concordance index (C-index) and calibration curve. Results: Multivariate analysis identified lymph node metastasis (LNM), lymph-vascular space invasion (LVSI), stromal invasion, parametrial invasion, tumor diameter and histology as independent prognostic factors associated with cervical cancer survival. These factors were selected for construction of the nomogram. The C-index of the nomogram was 0.71 (95% CI, 0.65 to 0.77), and calibration of the nomogram showed good agreement between the 5-year predicted survival and the actual observation. Conclusions: We developed a nomogram predicting 5-year overall survival of surgically treated stage IA-IIB cervical cancer patients. More comprehensive information that is provided by this nomogram could provide further insight into personalized therapy selection.

      • KCI등재

        Proposal of a Pretreatment Nomogram for Predicting Local Recurrence after Intensity-Modulated Radiation Therapy in T4 Nasopharyngeal Carcinoma: A Retrospective Review of 415 Chinese Patients

        Lu-Lu Zhang,Yi-Yang Li,Jiang Hu,Guan-Qun Zhou,Lei Chen,Wen-Fei Li,Ai-Hua Lin,Jun Ma,Zhen-Yu Qi,Ying Sun 대한암학회 2018 Cancer Research and Treatment Vol.50 No.4

        Purpose Local relapse-free survival (LRFS) differs widely among patients with T4 category nasopharyngeal carcinoma (NPC). We aimed to build a nomogram incorporating clinicopathological information to predict LRFS in T4 NPC after definitive intensity-modulated radiation therapy (IMRT). Materials and Methods Retrospective study of 415 Chinese patients with non-metastatic T4 NPC treated with definitive IMRT with or without chemotherapy at our cancer center between October 2009 and September 2013. The nomogram for LRFS at 3 and 5 years was generated based on multivariate Cox proportional hazards regression, and validated using bootstrap resampling, assessing discriminative performance using the concordance index (C-index) and determining calibration ability via calibration curves. Results Five-year LRFS was 88.8%. We identified and incorporated four independent prognostic factors for LRFS: ethmoid sinus invasion, primary gross tumor volume, age, and pretreatment body mass index. The C-index of the nomogram for local recurrence was 0.732 (95% confidence interval, 0.726 to 0.738), indicating excellent predictive accuracy. The calibration curve revealed excellent agreement between nomogram-predicted and observed LRFS probabilities. Risk subgroups based on total point score cutoff values enabled effective discrimination of LRFS. Conclusion This pretreatment nomogram enables clinicians to accurately predict LRFS in T4 NPC after definitive IMRT, and could help to facilitate personalized patient counselling and treatment strategies.

      • KCI등재

        Robotics in Cervical Spine Surgery: Feasibility and Safety of Posterior Screw Placement

        Lu-Ping Zhou,Zhi-Gang Zhang,Dui Li,Shu Fang,Rui Sheng,Ren-Jie Zhang,Cai-Liang Shen 대한척추신경외과학회 2023 Neurospine Vol.20 No.1

        Objective: Robot-assisted (RA) techniques have been widely investigated in thoracolumbar spine surgery. However, the application of RA methods on cervical spine surgery is rare due to the complex morphology of cervical vertebrae and catastrophic complications. Thus, the feasibility and safety of RA cervical screw placement remain controversial. This study aims to evaluate the feasibility and safety of RA screw placement on cervical spine surgery. Methods: A comprehensive search on PubMed, Cochrane Library, Embase Database, Web of Science, Chinese National Knowledge Databases, and Wanfang Database was performed to select potential eligible studies. Randomized controlled trials (RCTs), comparative cohort studies, and case series reporting the accuracy of cervical screw placement were included. The Cochrane risk of bias criteria and Newcastle-Ottawa Scale criteria were utilized to rate the risk of bias of the included literatures. The primary outcome was the rate of cervical screw placement accuracy with robotic guidance; subgroup analyses based on the screw type and insertion segments were also performed. Results: One RCT, 3 comparative cohort studies, and 3 case series consisting of 160 patients and 719 cervical screws were included in this meta-analysis. The combined outcomes indicated that the rates of optimal and clinically acceptable cervical screw placement accuracy under robotic guidance were 88.0% (95% confidence interval [CI], 84.1%–91.4%; p = 0.073; I 2 = 47.941%) and 98.4% (95% CI, 96.8%–99.5%; p = 0.167; I2 = 35.954%). The subgroup analyses showed that the rate of optimal pedicle screw placement accuracy was 88.2% (95% CI, 83.1%–92.6%; p = 0.057; I2 = 53.305%); the rates of optimal screw placement accuracy on C1, C2, and subaxial segments were 96.2% (95% CI, 80.5%–100.0%; p = 0.167; I2 = 44.134X%), 89.7% (95% CI, 80.6%–96.6%; p = 0.370; I2 = 0.000X%), and 82.6% (95% CI, 70.9%–91.9%; p = 0.057; I2 = 65.127X%;), respectively. Conclusion: RA techniques were associated with high rates of optimal and clinically acceptable screw positions. RA cervical screw placement is accurate, safe, and feasible in cervical spine surgery with promising clinical potential.

      • KCI등재

        The type II histidine triad protein HtpsC facilitates invasion of epithelial cells by highly virulent Streptococcus suis serotype 2

        Lu Yunjun,Li Shu,Shen Xiaodong,Zhao Yan,Zhou Dongming,Hu Dan,Cai Xushen,Lu Lixia,Xiong Xiaohui,Li Ming,Cao Min 한국미생물학회 2021 The journal of microbiology Vol.59 No.10

        Streptococcus suis serotype 2 (S. suis 2) is an important zoonotic pathogen that presents a significant threat both to pigs and to workers in the pork industry. The initial steps of S. suis 2 pathogenesis are unclear. In this study, we found that the type II histidine triad protein HtpsC from the highly virulent Chinese isolate 05ZYH33 is structurally similar to internalin A (InlA) from Listeria monocytogenes, which plays an important role in mediating listerial invasion of epithelial cells. To determine if HtpsC and InlA function similarly, an isogenic htpsC mutant (ΔhtpsC) was generated in S. suis by homologous recombination. The htpsC deletion strain exhibited a diminished ability to adhere to and invade epithelial cells from different sources. Double immunofluorescence microscopy also revealed reduced survival of the ΔhtpsC mutant after cocultivation with epithelium. Adhesion to epithelium and invasion by the wild type strain was inhibited by a monoclonal antibody against E-cadherin. In contrast, the htpsC-deficient mutant was unaffected by the same treatment, suggesting that E-cadherin is the host-cell receptor that interacts with HtpsC and facilitates bacterial internalization. Based on these results, we propose that HtpsC is involved in the process by which S. suis 2 penetrates host epithelial cells, and that this protein is an important virulence factor associated with cell adhesion and invasion.

      • Expression of Ki67 in Papillary Thyroid Microcarcinoma and its Clinical Significance

        Zhou, Yuan,Jiang, Hong-Gang,Lu, Ning,Lu, Bo-Hao,Chen, Zhi-Heng Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.4

        Purpose: To investigate the expression of Ki67 protein in papillary thyroid microcarcinoma(PTMC), and to analyze its clinical significance. Materials and Methods: Ki67 protein expression was evaluated in the tissues of 108 human PTMC and 50 other benign papillary hyperplasia of thyroid specimens using immunohistochemistry. Results: The expression intensity of Ki67 in PTMC and benign papillary hyperplasia of thyroid specimens were $1.45{\pm}1.83%$ and $0.46{\pm}0.46%$.The positive expression rates were 46.3% and 14%. There were significant differences between these two groups (p<0.01). There was no significant variation of the expression intensity and positive expression rates of Ki67 in PTMC with gender, age, position of the tumor and the level of TSH pre-operation (p>0.05), but these parameters varied with tumor size, invasion by membrane and cervical lymph node metastasis (p<0.05 or p<0.01). Conclusions: The expression of Ki67 in PTMC was related to tumor size, invasion by membrane and cervical lymph node metastasis, and could be the important indicator for judging clinical progress and estimating prognosis.

      • SCIESCOPUS

        Real-time condition assessment of railway tunnel deformation using an FBG-based monitoring system

        Zhou, Lu,Zhang, Chao,Ni, Yi-Qing,Wang, Chung-Yue Techno-Press 2018 Smart Structures and Systems, An International Jou Vol.21 No.5

        A tunnel deformation monitoring system is developed with the use of fiber Bragg grating (FBG) sensing technique, aiming at providing continuous monitoring of railway tunnel deformation in the long term, and early warning for the rail service maintainers and authorities to avoid catastrophic consequences when significant deformation occurs. Specifically, a set of FBG bending gauges with the ability of angle measurement and temperature compensation is designed and manufactured for the purpose of online monitoring of tunnel deformation. An overall profile of lateral tunnel displacement along the longitudinal direction can be obtained by implementing an array of the FBG bending gauges interconnected by rigid rods, in conjunction with a proper algorithm. The devised system is verified in laboratory experiments with a test setup enabling to imitate various patterns of tunnel deformation before the implementation of this system in an in-service high-speed railway (HSR) tunnel.

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