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Enhanced Antibacterial Effect of Polypyrazole-Graphene Oxide Composite
Bin Yang,Yufei Wang,Longqiang Xiao,Xiaowen Hu,Guofu Zhou 한국고분자학회 2017 Macromolecular Research Vol.25 No.1
Besides excellent physical performances, graphene oxide (GO) has been widely acknowledged as a potential antibacterial material. Chemical modification of GO was taken out with polypyrazole by facile amidation in the presence of dicyclohexylcarbodiimide (DCC) and then generated polypyrazole-graphene oxide (FGO) nanohybrid. FGO nanohybrid showed smooth and multilayer structures by scanning electron microscopy. The value of static water contact angle of FGO is 103o, suggesting FGO was a hydrophobic material. Thermo gravimetric analysis of FGO showed a 65% mass loss up 50 to 600 oC, suggesting that FGO is a thermal stability material. Inactivation efficiency test of nominal Escherichia coli cells showed that the viability greatly decreased to 7% after 4 h incubation with FGO under 37 oC, indicating an outstanding antibacterial ability of FGO much better than that of polypyrazole and GO.