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임유진,이상명,김동수,김준범,최광식,이신혜,박정규,이동운,Lim, Eu-Gene,Lee, Sang-Myeong,Kim, Dong-Soo,Kim, Joon-Bum,Lee, Shin-Hye,Choi, Kwang-Sik,Park, Chung-Gyoo,Lee, Dong-Woon 한국응용곤충학회 2012 한국응용곤충학회지 Vol.51 No.1
솔껍질깍지벌레는 우리나라 곰솔림의 주요한 해충의 하나이다. 본 연구는 우리나라에서 솔껍질깍지벌레의 분포를 알아보기 위하여 7개도 3개 광역시, 91개 시군구, 686 읍면동의 해송림에서 2010년 밀도를 조사하였다. 5개도 2개 광역시에서 솔껍질깍지벌레가 서식하고 있었는데 시군구별로는 조사대상의 64.8%인 59개 시군구에서 서식이 확인되었다. 솔껍질깍지벌레의 분포는 남해안 전역과 동해안의 포항, 서해안의 충남 보령지역까지 분포하였다. 충북과 대전광역시 및 제주도에서는 솔껍질깍지벌레의 분포가 확인되지 않았다. 부산지역은 16곳의 모든 구에서 솔껍질깍지벌레가 분포하였고, 시군 단위에서는 전남 해남군의 솔껍질깍지벌레 평균밀도가 1.713마리/0.785 $cm^2$로 가장 높았으며 읍면동 단위에서는 해남군 송지면이 6.36마리/0.785 $cm^2$로 가장 높았다. 곰솔 가지 내의 솔껍질깍지벌레 밀도와 솔껍질깍지벌레가 서식하고 있는 빈도와는 높은 상관관계가 있었다(상관계수=0.89). The black pine bast scale, $Masucoccus$ $thunbergianae$ (Hemiptera: Margarodidae), is a serious pest of the Japanese black pine, $Pinus$ $thunbergii$, in Korea. The distribution of the black pine bast scale was examined, looking overall at 686 towns (eup), townships (myeon) or neighborhoods (dong). There were Japanese black pine ($Pinus$ $thunbergii$) forests in 91 cities, counties (gun) and borough (gu), in seven provinces and three metropolitan cities during 2010. Black pine bast scale were found in 64.8% of cities or counties or borough (59) in 7 provinces and 3 metropolitan cities, and were distributed in all South Costal regions, Pohang in East Costal region and Boryeong in West Costal region. Chungcheongbukdo, Daejeon and Jeju did not have black pine bast scale. All the gu regions in Busan had black pine bast scale, of which the area with the highest prevalence was Haenam in Jeollanamdo (1.713 crawlers/0.785 $cm^2$). Songji-myeon had the highest occurrence rate (6.36 crawlers/0.785 $cm^2$) from the towns, township and dong. The density of black pine bast scale in twigs was highly correlated with percentage of the sample with scale (Correlation coefficacy=0.89).
Park, Jinbong,Jeon, Yong-Deok,Kim, Hye-Lin,Lim, Hara,Jung, Yunu,Youn, Dong-Hyun,Jeong, Mi-Young,Kim, Hyun-Ju,Kim, Sung-Hoon,Kim, Su-Jin,Hong, Seung-Heon,Um, Jae-Young Hindawi Publishing Corporation 2013 Evidence-based Complementary and Alternative Medic Vol.2013 No.-
<P>Obesity has become a major health threat in developed countries. However, current medications for obesity are limited because of their adverse effects. Interest in natural products for the treatment of obesity is thus rapidly growing. Korean Medicine (KM) is characterized by the wide use of herbal formulas. However, the combination rule of herbal formulas in KM lacks experimental evidence. According to <I>Shennong's Classic of Materia Medica</I>, the earliest book of herbal medicine, <I>Veratrum nigrum</I> (VN) has antagonistic features against <I>Panax ginseng</I> (PG), and the PG-VN pair is strictly forbidden. In this study, we have shown the effects of PG, VN, and their combination on obesity in high-fat (HF) diet-induced obese mice and in 3T3-L1 cells. PG, VN, and PG-VN combination significantly reduced weight gain and the fat pad weight in HF diet-induced obese mice. They also significantly decreased lipid accumulation and the expressions of two major adipogenesis factors, PPAR<I><I>γ</I></I> and C/EBP<I><I>α</I></I>, in 3T3-L1 cells. In addition, the PG-VN combination had synergistic effects compared with the mixture of extracts of PG and VN on inhibition of PPAR<I><I>γ</I></I> and C/EBP<I><I>α</I></I> expressions at lower doses. These results indicate a new potential anti-obese pharmacotherapy and also provide scientific evidence supporting the usage of herbal combinations instead of mixtures in KM.</P>
Three-dimensional hierarchical Te-Si nanostructures.
Lim, Jae-Hong,Shin, Gyeong-Jin,Hwang, Tae-Yeon,Lim, Hyo-Ryoung,Lee, Young-In,Lee, Kyu-Hwan,Kim, Sung-Dae,Oh, Min-Wook,Park, Su-Dong,Myung, Nosang V,Choa, Yong-Ho RSC Pub 2014 Nanoscale Vol.6 No.20
<P>Three-dimensional hybrid nanostructures (i.e., Te 'nanobranches' on a Si 'nanotrunk' or Te 'nanoleaves' on a Si 'nanotrunk') were synthesized by combining the gold-assisted chemical etching of Si to form Si 'nanotrunks' and the galvanic displacement of Si to form Te 'nanobranches' or 'nanoleaves.' By adjusting the composition of the electrolyte used for the galvanic displacement reaction, the shape of the Te nanostructures could be changed from nanoleaves to nanobranches. The Si nanotrunks with Te nanobranches showed stronger luminescent emission in the visible region, with their Raman spectrum having a higher wave number, owing to their grain size being larger. This suggested that the optical and photoelectrochemical properties of Te-Si hybrid nanostructures depend on their shape and size. Using this approach, it should be possible to fabricate various hierarchical nanostructures for use in photoelectronic and photoelectrochemical devices.</P>
Development of a Qualitative Dose Indicator for Gamma Radiation Using Lyophilized Deinococcus
( Lim Sang Yong ),( Du Sup Song ),( Min Ho Joe ),( Dong Ho Kim ) 한국미생물 · 생명공학회 2012 Journal of microbiology and biotechnology Vol.22 No.9
The feasibility of using Deinococcus showing strong resistance to both desiccation and ionizing radiation as a dose indicator of gamma radiation exposure was evaluated. Three Deinococcus strains having different levels of radiation resistance, Deinococcus radiodurans (DRD), Deinococcus radiopugnans (DRP), and the DRD pprI mutant (DRM), were selected to develop an appropriate dose indicator for a broad range of exposures. DRD, DRP, and DRM cultures with different numbers of cells [~107 to 103 colony forming units (CFU)/100 ul] were lyophilized and subjected to various doses of gamma radiation to determine a critical dose that inhibited bacterial growth completely, Finally, a combination of DRD at ~107 and ~106 CFU, DRP at ~105 CFU, and DRM at ~104 CFU successfully indicated exposure to 5, 10, 20, and 30 kGy of gamma radiation, respectively, This study shows the possibility of developing a qualitative indicator of radiation exposure using Deinococcus.
Dong Su Son,Tae Young Lee,Sang Ho Lim,Seong-Rae Lee IEEE 2014 IEEE transactions on magnetics Vol.50 No.11
<P>We prepared [Pt/(Co, Cu)] multilayers with a very thin (i.e., 0.2 nm thick) Pt layer and a thicker (i.e., 0.4, 0.5, or 0.6 nm thick) (Co, Cu) layer and investigated the effects of the Cu content in the (Co, Cu) layer and the postannealing temperature on the magnetic properties of the multilayers. The samples in the as-deposited state and those annealed up to 500 °C for 1 h all exhibited perpendicular magnetic anisotropy (PMA). The PMA strength and saturation magnetization both decreased with increasing content of Cu in the samples. The saturation magnetization of the Cu containing multilayers annealed at 500 °C substantially decreased, probably owing to the change in the microstructure from a layered structure in the as-deposited samples to a bulk phase in the annealed ones, as supported by high resolution transmission electron microscopy images. The effective PMA energy density of the samples annealed at high temperatures, on the other hand, remained nearly unchanged and even increased slightly indicating a high postannealing stability of Cu containing multilayers. The Cu-containing multilayers may find potential application to high density magnetic random access memory as the pinned structure of magnetic tunnel junctions because the multilayers showed low saturation magnetizations in the range 164-753 emu/cm\(^{3}\) and high postannealing stability.</P>
Dong-Kuk Lim,Dong-Kyun Woo,Han-Kyeol Yeo,Sang-Yong Jung,Jong-Suk Ro,Hyun-Kyo Jung IEEE 2015 IEEE transactions on magnetics Vol.51 No.3
<P>To design electric machines, the motor performance, cost, and manufacturing have to be considered. Hence, researchers have called this the multi-objective optimization (MOO) problem in which the goal is to minimize or maximize several objective functions at the same time. In order to solve the MOO problem, various algorithms, such as nondominated sorting genetic algorithm II and multi-objective particle swarm optimization, have been widely used. When these algorithms are applied to the electric machine design, much time consumption is inevitable due to many times of function evaluations using a finite-element method. To solve this problem, a novel surrogate-assisted MOO algorithm is proposed. Its validity is confirmed by comparing the optimization results of test functions with conventional optimization methods. To verify the feasibility of its application to a practical electric machine, an interior permanent magnet synchronous motor is designed.</P>
Lim, Dong Hwan,Lee, Seok Jae,Koo, Ja Ryong,Kim, Bo Young,Shin, Hyun Su,Lee, Kum Hee,Lee, Sang Youn,Kim, Woo Young,Yoon, Seung Soo,Kim, Young Kwan American Scientific Publishers 2014 Journal of nanoscience and nanotechnology Vol.14 No.8
<P>We report an improvement of efficiency in red phosphorescent organic light-emitting diodes (PHOLEDs) based on a combination of heterojunction (HJ) structure and mixed host (MH) system using a phosphorescent red emitter: bis(2-phenylquinolinato)-acetylacetonate iridium III [Ir(pq)2(acac)] doped in 4,4,N,N'-dicarbazolebiphenyl (CBP) of hole transport type host material and 1,3,5-tris(N-phenylbenzimidazole-2-yl)benzene (TPBi) of electron transport type host material. This combination device resulted in an effective electron and hole balance and distribution of the recombination zone. Therefore, highly efficient red PHOLEDs with maximum luminous efficiency and external quantum efficiency of 21.93 cd/A and 14.09% were achieved. Moreover, the combination device showed a power efficiency of 9.51 lm/W, which is higher than 7.61 lm/W in the control device at a luminance of 1000 cd/m2.</P>
Lim, Mi-Sun,Chang, Mi-Yoon,Kim, Sang-Mi,Yi, Sang-Hoon,Suh-Kim, Haeyoung,Jung, Sung Jun,Kim, Min Jung,Kim, Jin Hyuk,Lee, Yong-Sung,Lee, Soo Young,Kim, Dong-Wook,Lee, Sang-Hun,Park, Chang-Hwan American Society for Biochemistry and Molecular Bi 2015 The Journal of biological chemistry Vol.290 No.28
<P>Recent groundbreaking work has demonstrated that combined expression of the transcription factors <I>Brn2</I>, <I>Ascl1</I>, and <I>Myt1L</I> (BAM; also known as Wernig factors) convert mouse fibroblasts into postmitotic neuronal cells. However, questions remain regarding whether trans-conversion is achieved directly or involves an intermediary precursor stage. Trans-conversion toward expandable neural precursor cells (NPCs) is more useful than direct one-step neuron formation with respect to yielding a sufficient number of cells and the feasibility of manipulating NPC differentiation toward certain neuron subtypes. Here, we show that co-expression of Wernig factors and <I>Bcl-xL</I> induces fibroblast conversion into NPCs (induced NPCs (iNPCs)) that are highly expandable for >100 passages. Gene expression analyses showed that the iNPCs exhibited high expression of common NPC genes but not genes specific to defined embryonic brain regions. This finding indicated that a regional identity of iNPCs was not established. Upon induction, iNPCs predominantly differentiated into astrocytes. However, the differentiation potential was not fixed and could be efficiently manipulated into general or specific subtypes of neurons by expression of additional genes. Specifically, overexpression of <I>Nurr1</I> and <I>Foxa2</I>, transcription factors specific for midbrain dopamine neuron development, drove iNPCs to yield mature midbrain dopamine neurons equipped with presynaptic DA neuronal functions. We further assessed the therapeutic potential of iNPCs in Parkinson disease model rats.</P>