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- 저자 : Lilyasari Oktavia (검색결과 3 건)
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Oktavia Lilyasari,Muhamad Adrin AP,Radityo Prakoso,Arwin Saleh Mangkuanom,Aditya Agita Sembiring,Nurnajmia Curie Proklamartina,Amiliana M Soesanto 아시아심장혈관영상의학회 2024 Cardiovascular Imaging Asia Vol.8 No.2
Objective: Uncorrected atrial septal defect (ASD) leads to pulmonary vascular disease (PVD) later in adulthood. Attempts to close the defect have proven to be detrimental in the presence of PVD. Although right heart catheterization (RHC) is the gold standard for PVD, it remains an invasive approach with complications. Notch characteristics on the right ventricular outflow tract (RVOT) Doppler correlate well with parameters of pulmonary hypertension. Therefore, this study evaluated whether time-to-notch RVOT Doppler could detect PVD in adults with ASD. Materials and Methods: Between March 2019 and June 2020, we consecutively sampled adult patients with ostium secundum ASD. Time-to-notch was examined by transthoracic echocardiogram within 24 hours of RHC. A vasoreactivity test was performed when the ratio of resistance arterial pulmonary to systemic (PVR:SVR) was ≥0.33. PVD was diagnosed if the final resistance ratio was ≥0.33. Results: We analysed 89 subjects with ASD. A vasoreactivity test was performed in 54 patients with pure oxygen, and 37% (n=24) had PVD. The majority of subjects in this study were women (85%) with a median age of 38 years. The time-to-notch RVOT Doppler was significantly shorter in subjects with PVD compared to those without (132±17 ms vs. 177±29 ms, p<0.001). The area under the curve was 0.923 for time-to-notch to predict PVR:SVR ≥0.33. A cutoff point of <147.5 ms was able to detect PVD (sensitivity 88%, specificity 87%, positive predictive value 72%, negative predictive value 95%, positive likelihood ratio [LR] 7.11, and negative LR 0.14). Conclusion: Time-to-notch RVOT Doppler has substantial predictive value in detecting PVD in secundum ASD-pulmonary arterial hypertension populations.
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Goo Hyun Woo,Siripornpitak Suvipaporn,Chen Shyh-Jye,Lilyasari Oktavia,Zhong Yu-Min,Latiff Haifa Abdul,Maeda Eriko,Kim Young Jin,Tsai I-Chen,Seo Dong Man 대한영상의학회 2021 Korean Journal of Radiology Vol.22 No.8
The use of pediatric cardiothoracic CT for congenital heart disease (CHD) was traditionally limited to the morphologic evaluation of the extracardiac thoracic vessels, lungs, and airways. Currently, the applications of CT have increased, owing to technological advancements in hardware and software as well as several dose-reduction measures. In the previously published part 1 of the guideline by the Asian Society of Cardiovascular Imaging Congenital Heart Disease Study Group, we reviewed the prerequisite technical knowledge for clinical applications in a user-friendly and vendor-specific manner. Herein, we present the second part of our guideline on contemporary clinical applications of pediatric cardiothoracic CT for CHD based on the consensus of experts from the Asian Society of Cardiovascular Imaging CHD Study Group. This guideline describes up-to-date clinical applications effectively in a systematic fashion.
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Harlyjoy Beta C.,Roebiono Poppy S.,Kurniawati Yovi,Prakoso Radityo,Lilyasari Oktavia 아시아심장혈관영상의학회 2022 Cardiovascular Imaging Asia Vol.6 No.3
Objective:Partial anomalous pulmonary vein drainage (PAPVD) describes a pattern where ≥1, but not all, pulmonary veins do not drain into the left atrium. It has traditionally been associated with atrial septal defects (ASDs). Due to silent clinical manifestations, a PAPVD diagnosis can pose a challenge for physicians. Trans-thoracic echocardiography (TTE) is used to diagnose PAPVD yet sometimes provides insufficient information. This study sought to observe the clinical characteristics of PAPVD patients, diagnostic modalities, and the relationship of PAPVD to ASD diagnosis. Materials and Methods: We collected medical records data of PAPVD patients seen at our centre, the National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia, from January 2012 to May 2021. Results:This study included 84 patients. Initial TTE examinations were performed in all cases. Concomitant ASD was seen in 95.2% of the patients, with 65.5% of cases being the sinus venous defect type and the rest being the secundum type. An inability to determine PAPVD diagnosis through initial TTE exam occurred in 26.2% of patients. From that group, most of the PAPVD diagnoses were determined through right heart catheterisation (54.5%); others were confirmed using intraoperative findings (22.7%), computed tomography imaging (13.6%), magnetic resonance imaging (4.5%), and trans-esophageal echocardiography (4.5%). The backward regression model showed that the type of ASD (p=0.023) and age (p=0.024) are predictors of diagnostic discrepancy, with odds ratios for the type of ASD and age being 3.93 and 1.04. Conclusion:Older PAPVD patients with secundum-type ASD pose a greater diagnostic challenge to determining pulmonary vein drainage during the initial TTE exam examination.
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