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      • KCI등재

        Theoretical Investigation on Collinear Phase Matching Stimulated Polariton Scattering Generating THz Waves with a KTP Crystal

        Lian Tan,Bin Yuan,이용준,Silei Wang,Hongtao Zhang,Pibin Bing,Jianquan Yao,Zhongyang Li 한국광학회 2019 Current Optics and Photonics Vol.3 No.4

        We present a theoretical research concerning terahertz (THz) wave generation with KTiOPO 4 (KTP) by collinear phase matching (CPM) stimulated polariton scattering (SPS). Both CPM and corresponding nonzero nonlinear coefficients can be simultaneously realized with s→f+f in yz plane, s→f+s with θ < Ω in xz plane and s→f+f with θ > Ω in xz plane. The effective nonlinear coefficients including electronic nonlinearities and ionic nonlinearities are calculated. Based on the parameter values of refractive indices, absorption coefficients and effective nonlinear coefficients, we simulate THz wave intensities generated with CPM SPS by solving coupled wave equations and give the relationship among the maximum THz wave intensity, optimal crystal length and the angle θ. The calculation results demonstrate that CPM SPS with KTP can generate THz waves with high intensities and quantum conversion efficiencies.

      • KCI등재

        Impact of timely BCR-ABL1 monitoring before allogeneic stem cell transplantation among patients with BCR-ABL1-positive B-acute lymphoblastic leukemia

        Siew Lian Chong,Asral Wirda Ahmad Asnawi,Tze Shin Leong,Jenq Tzong Tan,Kian Boon Law,Siong Leng Hon,Rui Jeat Fann,Sen Mui Tan 대한혈액학회 2021 Blood Research Vol.56 No.3

        Background With the emergence of tyrosine kinase inhibitors and the incorporation of stringent measurable residual disease (MRD) monitoring, risk stratification for BCR-ABL1-positive acute lymphoblastic leukemia (ALL) patients has changed significantly. However, whether this monitoring can replace conventional risk factors in determining whether patients need allogeneic stem cell transplantation is still unclear. This study aimed to determine the impact of BCR-ABL1 monitoring on the outcome of patients with BCR-ABL1-positive ALL after allogeneic stem cell transplantation. Methods We retrospectively analyzed the survival outcome of patients with BCR-ABL1-positive ALL based on the quantification of BCR-ABL1 at 3 timepoints: the end of induction (timepoint 1), post-consolidation week 16 (timepoint 2), and the end of treatment for patients who were either transplant-eligible or non-transplant eligible (timepoint 3). Results From 2006 to 2018, a total of 96 patients newly diagnosed with BCR-ABL1-positive ALL were treated with chemotherapy and tyrosine kinase inhibitors. Thirty-eight (41.3%) patients achieved complete remission, and 33 patients underwent allogeneic stem cell transplantation. Our data showed that pre-transplant MRD monitoring by real-time quantitative polymerase chain reaction had the highest correlation with survival in patients with BCR-ABL1-positive ALL, especially for those who underwent allogeneic stem cell transplantation. Conclusion Patients without MRD pre-transplantation had superior survival compared with those who had MRD, and they had excellent long-term outcomes after allogeneic stem cell transplantation.

      • SCIESCOPUSKCI등재

        Visualizing test on the pass-through and collision characteristics of coarse particles in a double blade pump

        Tan, Minggao,Lian, Yichao,Liu, Houlin,Wu, Xianfang,Ding, Rong The Society of Naval Architects of Korea 2018 International Journal of Naval Architecture and Oc Vol.10 No.1

        As the key equipment in deep ocean mining, the slurry pump suffers from wear and blocking problems. In this paper, high-speed photography technique is applied to track the movement rule of single particle of the coarse particle solid-liquid two-phase flow in a double blade slurry pump. The influences of particle diameter and particle density on the pass-through and collision characteristics of particles are analyzed as well. The results show that the average of the passing pump time first decreases and then increases when the particle diameter increases. The average of the passing pump time decreases by 22.7%, when the particle density increases from $1.09g/cm^3$ to $1.75g/cm^3$. Besides, the particle density has great influence on the location where the particle hits the tongue. Most particles of $1.09g/cm^3$ hit the tongue on the left side, while collision location of particles of $1.75g/cm^3$ is mainly on the top and at the right side of the tongue. The research can provide a basis for the optimization design of slurry pump in deep ocean mining system.

      • KCI등재

        Visualizing test on the pass-through and collision characteristics of coarse particles in a double blade pump

        Minggao Tan,Yichao Lian,Houlin Liu,Xianfang Wu,Rong Ding 대한조선학회 2018 International Journal of Naval Architecture and Oc Vol.10 No.1

        As the key equipment in deep ocean mining, the slurry pump suffers from wear and blocking problems. In this paper, high-speed photography technique is applied to track the movement rule of single particle of the coarse particle solideliquid two-phase flow in a double blade slurry pump. The influences of particle diameter and particle density on the pass-through and collision characteristics of particles are analyzed as well. The results show that the average of the passing pump time first decreases and then increases when the particle diameter increases. The average of the passing pump time decreases by 22.7%, when the particle density increases from 1.09 g/cm3 to 1.75 g/cm3. Besides, the particle density has great influence on the location where the particle hits the tongue. Most particles of 1.09 g/cm3 hit the tongue on the left side, while collision location of particles of 1.75 g/cm3 is mainly on the top and at the right side of the tongue. The research can provide a basis for the optimization design of slurry pump in deep ocean mining system.

      • KCI등재

        Polarity-enhanced Gas-Sensing Performance of Au-Loaded ZnO Nanospindles Synthesized via Precipitation and Microwave Irradiation

        Yan Li,Tan Lv,Fang-Xian Zhao,Xiao-xue Lian,Yun-ling Zou,Qiong Wang 대한금속·재료학회 2016 ELECTRONIC MATERIALS LETTERS Vol.12 No.3

        Loading noble metal and exploring suitable morphology to achieveexcellent gas-sensing performance is very crucial for the fabrication ofgas sensors. We have successfully synthesized Au-loaded ZnO (Au/ZnO) nanospindles (NSs) through a really facile procedure involving aprecipitation and subsequent microwave irradiation. The as-preparedproducts have been characterized by X-ray diffraction (XRD), scanningelectron microscope (SEM). The formation and gas-sensing mechanismof Au/ZnO NSs were discussed. The SEM micrographs revealed aninteresting morphological evolution of the Au/ZnO NSs with Auloadingcontent ranging from 0 at. % to 7 at. %. The nanostructures wereemployed for gas-sensing measurement toward various gases. Itindicated that the Au/ZnO NSs based sensor showed a highly enhancedresponse (226.81) to 400 ppm acetone gas at a relatively low workingtemperature (270°C), and exhibited a fast response (1 s) and recoveryspeed (10 s). The highly enhanced acetone gas sensitivity of Au/ZnONSs based sensor could be attributed to its enhanced polarity owing tothe peculiar morphology, Schottcky barriers, as well as catalytic effect ofAu NPs.

      • KCI등재

        Preparation of ZnO Nanoparticles by Combustion Method and Their Gas Sensing Properties

        Xiao-xue Lian,Yan Li,Tan Lv,Yun-ling Zou,Dongmin An,Nan Zhang 대한금속·재료학회 2016 ELECTRONIC MATERIALS LETTERS Vol.12 No.1

        In this study, ZnO nanoparticles were fabricated using a simpleand novel combustion method without calcination. The sensormaterial was structurally and morphologically characterizedusing simultaneous differential scanning calorimetry (DSC),thermogravimetric analysis (TGA), x-ray diffraction (XRD),scanning electron microscopy (SEM), Brunauer-Emmett-Teller(BET), and transmission electron microscopy (TEM). Thesample containing 3 mol tartaric acid (ZTC-3) exhibitedexcellent ethanol sensing properties at the optimum temperatureof 330°C. The relationships among the gas response, temperature,response time (recovery time), concentration, and gas specieswere investigated. The ZTC-3 exhibited response and recoverytimes of 7 and 38 s to 100 ppm ethanol, as well as excellentresponse and good selectivity to ethanol gas. Such a ZnOnanoparticle structure could be potentially use for fabricatingethanol sensors.

      • KCI등재

        Multi-time Scale Coordinated Optimization of New Energy High Permeability Power System Considering Flexibility Requirements

        Su Shiwei,Tan Donghong,Li Xianghua,Li Xin,Chen Zitong,Lian Ruiqing,Lenz Soronga Blaise Kevine 대한전기학회 2023 Journal of Electrical Engineering & Technology Vol.18 No.2

        The high proportion of grid-connected intermittent energy such as wind power and photovoltaic makes the demand for power system flexibility increase sharply. In order to improve the overall flexibility of new energy high permeability system and enhance the economy of power system, promote the new energy consumption of system. This paper presents a multi-time scale Coordinated optimization strategy for the new energy high permeability power system considering flexibility requirement (MTSCOSFR). This strategy makes full use of the adjustment ability of source-load-storage flexible resources and analyzes system flexibility requirements at different time scales, creates multi-time scale optimization scheduling models, including typical week operation simulation model, typical day operation simulation model, typical period operation simulation model. Puts the profit of carbon trading and the penalty cost of insufficient flexibility into the optimization goal. Adopts the idea of multi-time coordination and step-by-step optimization to solve the model. This paper sets two cases to discuss MTSCOSFR. The results show that the comprehensive cost of the typical weekly operation simulation is reduced to 2360 × 104$, the penalty cost of insufficient flexibility in the typical day operation simulation is reduced by 67%, the flexibility capacity increased by 500 MW, the regulation capacity increased by 300 MW, the ramp margin increased by 1500 MW/(5 min) −1. The proposed strategy can improve system flexibility and promote new energy consumption on the basis of ensuring system economy.

      • Incorporating Prior Knowledge into Extension Neural Network and its Application to Recognition of Safety Status Pattern of Coal Mines

        Yu Zhou,Lian Tan 보안공학연구지원센터 2015 International Journal of Signal Processing, Image Vol.8 No.4

        Incorporating prior knowledge (PK) into learning methods is an effective means to improve learning performance. On the bases of requirements of engineering practice and the characteristics of knowledge representation of extension neural network (ENN), with the purpose of further improving the performance of ENN in engineering practice, a prior-knowledge-based ENN (PKENN) recognition method is proposed and applied in the application of safety status pattern recognition of coal mines in this paper. The PKENN recognition method effectively combines domain knowledge with training data set. The prior knowledge can provide additional information about the classical domain of characteristic vector that may compensate for the low quality of training data in a complex application environment. This method can set the initial weights of ENN, guide the learning of ENN and alleviate the learning burden. To demonstrate the validity and effectiveness of the proposed method, a real-world application on the geological safety status pattern recognition of coal mines is tested. Comparative experiments with existing methods and other ANN-based methods are conducted. The experimental results show that the proposed PKENN recognition method has a better performance.

      • Intensity-Modulated Radiotherapy for Nasopharyngeal Carcinoma: Penang General Hospital Experience

        Phua, Chee Ee,Tan, Boon Seang,Tan, Ai Lian,Eng, Kae Yann,Ng, Bong Seng,Malik, Rozita Abdul,Ishak, Wan Zamaniah Wan Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.7

        Purpose: To study the overall treatment time (OTT) and acute toxicity of intensity-modulated radiotherapy (IMRT) treatment for nasopharyngeal carcinoma (NPC). Methods: This retrospective study covered all NPC patients who underwent radical IMRT treatment at the Penang General Hospital from June 2011 to February 2012. Patients of any age and stage of disease with histologically proven diagnosis were included. Information was collected on patient demographics, clinical stage, treatment received, including any neoadjuvant and/or concurrent chemotherapy, acute toxity and completion of IMRT within the OTT. Results: A total of 26 NPC patients were treated with IMRT during the study period; 88.5% had stage III/IV disease. 45.2% received neo-adjuvant chemotherapy while 50.0% were given concurrent chemo-irradiation. All patients completed the treatment and 92.3% within the 7 weeks OTT. Xerostomia was present in all patients with 92.3% having grade 2. Severe grade III/IV acute toxicity occurred in 73.1% of patients, the commonest of which was oral mucositis (57.6%). This was followed by dysphagia which occurred in 53.8%, skin reactions in 42.3% and weight loss in 19.2%. However, haematological toxicity was mild with only one patient having leucopaenia. Conclusion: IMRT treatment for NPC is feasible in our center. More importantly, it can be delivered within the 7 weeks OTT in the majority of patients. Severe grade 3/4 toxicity is very common (73.1%) and thus maximal nutritional and analgesic support is required throughout the treatment.

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