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Li Xiying,Li Xiaojuan,Wang Xian,Yin Xuan,Li Shanshan,Wu Junyi,Ren Xiumei,Zhang Wei,Mi Yiqun,Xu Shifen 한국한의학연구원 2023 Integrative Medicine Research Vol.12 No.3
Background: We conducted this randomized controlled trial (RCT) to evaluate the effectiveness and safety of moxibustion at Sanyinjiao (SP6) acupoint for treatment of negative mood and sleep quality in healthcare workers during the 2019 coronavirus disease (COVID-19). Methods: A total of 180 participants were divided in a 1:1 ratio into two groups, the treatment group (for moxibustion) and the control group (for no treatment). The treatment group had a 30-minute moxibustion therapy once a day for two weeks, followed by a two-week follow-up. The Hamilton Anxiety Scale (HAMA) was used to assess the degree of the participants' anxiety, and the Patient Health Questionnaire-9 (PHQ-9) was utilized to examine their depressed condition. The Maslach Burnout Inventory-General Survey (MBI-GS) was used to measure the level of burnout among healthcare workers. To determine the severity of insomnia, the Sleep Dysfunction Rating Scale (SDRS) was utilized. At baseline, week 2, and week 4, all scales were evaluated. Results: Compared to the control group, The treatment group improved more significantly in the HAMA at week 2 (MD = -19.01, 95% CI: -21.89 to -16.14; P<0.001) and at week 4 follow-up visits (MD = -8.96, 95% CI: -11.19 to -6.73; P<0.001). A subgroup study of HAMA scores revealed that position and education had significant impact on treatment effectiveness. During the 2-week intervention period, the treatment group showed more significant improvements in depressive symptoms measured by PHQ-9 (13.00±2.41 vs. 15.60±3.65; P<0.001), work burnout symptoms measured by MBI-GS (MD = -11.88, 95% CI, -15.73 to -8.03; P<0.001), and insomnia symptoms measured by SDRS (MD = -2.45, 95% CI, -4.24 to -0.66; P<0.01). There were no significant adverse effects reported. Conclusion: Moxibustion at SP6 may be an effective treatment to improve anxiety, depression, sleep quality, and quality of life for healthcare workers during COVID-19.
Kinetics of transesterification of methyl acetate and n-octanol catalyzed by cation exchange resins
Yong Liu,Min Wei,Li Gao,Xiying Li,Liqun Mao 한국화학공학회 2013 Korean Journal of Chemical Engineering Vol.30 No.5
The transesterification kinetics of methyl acetate with n-octanol to octyl acetate and methanol were studied using Amberlyst 15 as catalyst in a batch stirred reactor. The influence of the agitation speed, particle size, temperature,catalyst loading, and initial reactants molar ratio was investigated in detail. A pseudo-homogeneous (PH) kinetic model was applied to correlate the experimental data in the temperature range of 313.15 K to 328.15 K. The estimated kinetic parameters made the calculated results in good agreement with the experimental data. A kinetic model describing the transesterification reaction catalyzed by cation exchange resins was developed.
Yong Liu,Yuefeng Wu,Miaojun Su,Weihua Liu,Xiying Li,Fujian Liu 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.92 No.-
A class of Brønsted–Lewis acid bifunctionalized ionic liquids based heteropolyacid hybrid (BLA-ILs-HPA)solid acids were developed by combining the double sulfonic groups grafted, ionic liquids basedheteropolyacid hybrid with Lewis acidic centers (M = Zn, Co, Fe, Ni, Cu). The prepared BLA-ILs-HPA showboth Brønsted and Lewis acidic sites with extremely-high acid strength and enhanced stabilities, asdetermined by FT-IR, Py-IR, TG, XPS and 31P solid state NMR results. BLA-ILs-HPA were successfullyapplied in esterification camphene with acetic acid to produce isobornyl acetate, and dehydration ofglucose to produce 5-hydrozymethylfural. BLA-ILs-HPA show enhanced catalytic activities in comparisonwith various acid catalysts. The effects of reaction temperatures, initial reactant molar ratio, catalystdosage, and reaction time were studied in detail. The optimal reaction conditions were obtained, and theexperimental data was successfully correlated by a pseudohomogeneous (PH) reaction kinetic model inthe temperature range of 313.15–333.15 K. The calculated values obtained by the reaction kinetic modelwere in good agreement with the experimental data. Moreover, as a heterogeneous reaction catalyst,BLA-ILs-HPA can be recovered by simple treatment. After six times cycling, the decreasing in the catalyticactivity of BLA-ILs-HPA could not be observed significantly, suggesting their good reusability.