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      • KCI등재

        Quantized DCT Coefficient Category Address Encryption for JPEG Image

        ( Shanshan Li ),( Yuanyuan Zhang ) 한국인터넷정보학회 2016 KSII Transactions on Internet and Information Syst Vol.10 No.4

        Digital image encryption is widely used for image data security. JPEG standard compresses image with great performance on reducing file size. Thus, to encrypt an image in JPEG format we should keep the quality of original image and reduced size. This paper proposes a JPEG image encryption scheme based on quantized DC and non-zero AC coefficients inner category scrambling. Instead of coefficient value encryption, the address of coefficient is encrypted to get the address of cipher text. Then 8*8 blocks are shuffled. Chaotic iteration is employed to generate chaotic sequences for address scrambling and block shuffling. Analysis of simulation shows the proposed scheme is resistant to common attacks. Moreover, the proposed method keeps the file size of the encrypted image in an acceptable range compared with the plain text. To enlarge the cipher text possible space and improve the resistance to sophisticated attacks, several additional procedures are further developed. Contrast experiments verify these procedures can refine the proposed scheme and achieve significant improvements.

      • KCI등재

        NF-jB activation was involved in reactive oxygen speciesmediated apoptosis and autophagy in 1-oxoeudesm-11(13)-eno- 12,8a-lactone-treated human lung cancer cells

        Shanshan Liu,Di Wu,Lin Li,Xiao Sun,Wei-Dong Xie,Xia Li 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.8

        1-oxoeudesm-11(13)-eno-12,8a-lactone (OEL),a novel eudesmane-type sesquiterpene compound, has beenshown to inhibit the growth of some cancer cell lines andinduce significant apoptosis. Here, we investigated the anticanceractivities of OEL in human lung cancer cells. Ourstudies demonstrated that OEL induced both apoptosis andautophagy in A549 and H460 cells. OEL-induced autophagywas assessed by appearance of autophagic vacuoles,formation of acidic vesicular organelles, conversion ofLC3-I to LC3-II, recruitment of LC3-II to the autophagosomes,and activation of autophagy genes. Furthermore,administration of autophagic inhibitor 3-methyladenineaugments OEL-induced apoptotic cell death. The inductionof autophagy and apoptosis by OEL links to NF-jB activationand the generation of reactive oxygen species (ROS). Interruption of NF-jB activation by specific inhibitor promotesapoptosis, but decreases autophagy. ROS antioxidants(N-acetylcysteine) attenuated both OEL-inducedautophagy and apoptosis. Further experiments confirmedthat OEL-induced activation of ROS was increased by NFjBinhibitor whereas NF-jB activation was not affected by ROS inhibition. These findings suggest that OEL-elicitedautophagic response plays a protective role that impedescell death, and inhibition of autophagy could be anadjunctive strategy for enhancing the chemotherapeuticeffect of OEL as an antitumor agent.

      • An improved procedure for generating standardised load-time histories for marine structures

        Li, Shanshan,Cui, Weicheng,Paik, Jeom Kee SAGE Publications 2016 Proceedings of the Institution of Mechanical Engin Vol.230 No.2

        <P>The load sequence effect has been proved from laboratory tests to be an influencing factor that cannot be neglected in the fatigue analysis of marine structures. To take account of this significant factor, fatigue life prediction should be based on fatigue crack propagation theory rather than the currently used cumulative fatigue damage theory. Accordingly, fatigue loading needs to be provided as the load-time history in the time domain rather than the load spectrum in the frequency domain. A general procedure for generating the standardised load-time history for marine structures based on a short-term load measurement has been proposed by the authors. This article seeks to further improve on this procedure and explain how to apply the determined standardised load-time history in the fatigue life prediction method based on the fatigue crack propagation theory. Finally, generation and application of a standardised load-time history are given for a tubular T-joint of an offshore platform, which demonstrates the practical and effective use of the proposed approach.</P>

      • KCI등재

        Coral‑Like NiFe2O4/C Composite as the High‑Performance Anode Material for Lithium‑Ion Batteries

        Shanshan Bao,Yifei Xiao,Junfeng Li,Bo Yue,Yanjun Li,Wenxian Sun,Lei Liu,Yi Huang,Li Wang,Peicong Zhang,Xuefei Lai 대한금속·재료학회 2020 ELECTRONIC MATERIALS LETTERS Vol.16 No.3

        In this work, we fabricated NiFe2O4/C composite with a coral-like structure through co-precipitation approach followed bythermal decomposition. The composite with a large surface area of 162.1 m2 g−1 and an average pore size of 11.8 nm wasobtained. The porous structure in the composite derived from oxalate can Effectively accommodate the volume changesof NiFe2O4 during the cycling processes. When used as anode materials, the initial charge and discharge capacities of thecomposite were 926.7 and 1277.7 mAh g−1 at 100 mA g−1. After 50 cycles, the reversible capacity of NiFe2O4/C could stillremain at 892.4 mAh g−1. Even at a current density of 2000 mA g−1, the reversible capacity still reached 523.3 mAh g−1. The results showed that the synergy between NiFe2O4 and carbon improved the electrochemical performance, and the porouscomposite could stabilize the structure of the electrode.

      • KCI등재

        A Multilevel Analysis of the Chinese Super League: Examining the Game Level and Home Team Level Determinants of Stadium Attendance

        Shanshan Li,Yoonji Ryu,Hansol Kim 글로벌지식마케팅경영학회 2022 Journal of Global Sport Management Vol.7 No.4

        The Chinese Super League (CSL) is the top tier football league in China and over the past 10 years has expanded rapidly in terms of popularity, brand strength, and name recognition. Despite the CSL’s rapid development, limited empirical research has been done to examine the league and what drives demand in attending the games. Thus, in order to gain a better understanding of CSL and identify unique patterns of demand for professional sports leagues in China, this study used data from the 2017–2019 CSL regular seasons to examine the relationship between various stadium determinants and game attendance. Moreover, the nested structure found in attendance data was considered, thus adopting multilevel modeling (MLM) to analyze game level and home team level variables to predict stadium attendance in the CSL. Our findings reveal that 12 variables significantly influenced attendance, with variables related to home teams showing more relevance to explaining stadium attendance than game level variables.

      • KCI등재

        Moxibustion for medical personnel with negative emotion and insomnia during COVID-19 pandemic: A randomized, controlled trial

        Li Xiying,Li Xiaojuan,Wang Xian,Yin Xuan,Li Shanshan,Wu Junyi,Ren Xiumei,Zhang Wei,Mi Yiqun,Xu Shifen 한국한의학연구원 2023 Integrative Medicine Research Vol.12 No.3

        Background: We conducted this randomized controlled trial (RCT) to evaluate the effectiveness and safety of moxibustion at Sanyinjiao (SP6) acupoint for treatment of negative mood and sleep quality in healthcare workers during the 2019 coronavirus disease (COVID-19). Methods: A total of 180 participants were divided in a 1:1 ratio into two groups, the treatment group (for moxibustion) and the control group (for no treatment). The treatment group had a 30-minute moxibustion therapy once a day for two weeks, followed by a two-week follow-up. The Hamilton Anxiety Scale (HAMA) was used to assess the degree of the participants' anxiety, and the Patient Health Questionnaire-9 (PHQ-9) was utilized to examine their depressed condition. The Maslach Burnout Inventory-General Survey (MBI-GS) was used to measure the level of burnout among healthcare workers. To determine the severity of insomnia, the Sleep Dysfunction Rating Scale (SDRS) was utilized. At baseline, week 2, and week 4, all scales were evaluated. Results: Compared to the control group, The treatment group improved more significantly in the HAMA at week 2 (MD = -19.01, 95% CI: -21.89 to -16.14; P<0.001) and at week 4 follow-up visits (MD = -8.96, 95% CI: -11.19 to -6.73; P<0.001). A subgroup study of HAMA scores revealed that position and education had significant impact on treatment effectiveness. During the 2-week intervention period, the treatment group showed more significant improvements in depressive symptoms measured by PHQ-9 (13.00±2.41 vs. 15.60±3.65; P<0.001), work burnout symptoms measured by MBI-GS (MD = -11.88, 95% CI, -15.73 to -8.03; P<0.001), and insomnia symptoms measured by SDRS (MD = -2.45, 95% CI, -4.24 to -0.66; P<0.01). There were no significant adverse effects reported. Conclusion: Moxibustion at SP6 may be an effective treatment to improve anxiety, depression, sleep quality, and quality of life for healthcare workers during COVID-19.

      • KCI등재

        Layer-by-Layer Self-assembly of Organic-inorganic Hybrid Intumescent Flame Retardant on Cotton Fabrics

        Shanshan Li,Fang Ding,Xinghuan Lin,Zhiguang Li,Xuehong Ren 한국섬유공학회 2019 Fibers and polymers Vol.20 No.3

        In this study, a novel organic-inorganic hybrid intumescent flame-retardant composed of nanosilica (SiO2) coveredwith polyethyleneimine (PEI) and phytic acid (PA) was coated on cotton fabrics by layer-by-layer (LbL) self-assembly toimprove flame retardancy of cotton fabrics. FT-IR, SEM and EDX were used to characterize the deposition of SiO2-PEI/PA on the surface of cotton fabrics. The LbL assembly process had a minor effect on the tensile strength of cotton fabrics. With the synergistic effect of phosphorus, nitrogen and silicon, the coated cotton fabrics with only 7 bilayers exhibited excellent flame retardancy with an LOI value of 33.7 % and a char length of 7.5 cm. TG analysis results showed that cotton/(SiO2-PEI/PA)7 had 40.7 % char residue at 600 oC, compared with 8 % char residue of uncoated cotton fabrics. Cone calorimetry test confirmed that cotton/(SiO2-PEI/PA)7 displayed a major reduction in peak of heat release rate (pHRR) of 75 % and total heat release (THR) of 52 %.

      • SCIESCOPUSKCI등재

        Cordycepin protects against β–amyloid and ibotenic acid– induced hippocampal CA1 pyramidal neuronal hyperactivity

        Li-Hua Yao,Jinxiu Wang,Chao Liu,Shanshan Wei,Guoyin Li,Songhua Wang,Wei Meng,Zhi-Bin Liu,Li-Ping Huang 대한약리학회 2019 The Korean Journal of Physiology & Pharmacology Vol.23 No.6

        Cordycepin exerts neuroprotective effects against excitotoxic neuronal death. However, its direct electrophysiological evidence in Alzheimer’s disease (AD) remains unclear. This study aimed to explore the electrophysiological mechanisms underlying the protective effect of cordycepin against the excitotoxic neuronal insult in AD using whole-cell patch clamp techniques. β-Amyloid (Aβ) and ibotenic acid (IBO)–induced injury model in cultured hippocampal neurons was used for the purpose. The results revealed that cordycepin significantly delayed Aβ + IBO–induced excessive neuronal membrane depolarization. It increased the onset time/latency, extended the duration, and reduced the slope in both slow and rapid depolarization. Additionally, cordycepin reversed the neuronal hyperactivity in Aβ + IBO–induced evoked action potential (AP) firing, including increase in repetitive firing frequency, shortening of evoked AP latency, decrease in the amplitude of fast afterhyperpolarization, and increase in membrane depolarization. Further, the suppressive effect of cordycepin against Aβ + IBO–induced excessive neuronal membrane depolarization and neuronal hyperactivity was blocked by DPCPX (8-cyclopentyl-1,3-dipropylxanthine, an adenosine A1 receptor–specific blocker). Collectively, these results revealed the suppressive effect of cordycepin against the Aβ + IBO–induced excitotoxic neuronal insult by attenuating excessive neuronal activity and membrane depolarization, and the mechanism through the activation of A1R is strongly recommended, thus highlighting the therapeutic potential of cordycepin in AD.

      • KCI등재

        Cordycepin protects against β–amyloid and ibotenic acid– induced hippocampal CA1 pyramidal neuronal hyperactivity

        Li-Hua Yao,Jinxiu Wang,Chao Liu,Shanshan Wei,Guoyin Li,Songhua Wang,Wei Meng,Zhi-Bin Liu,Li-Ping Huang 대한약리학회 2019 The Korean Journal of Physiology & Pharmacology Vol.23 No.6

        Cordycepin exerts neuroprotective effects against excitotoxic neuronal death. However, its direct electrophysiological evidence in Alzheimer’s disease (AD) remains unclear. This study aimed to explore the electrophysiological mechanisms underlying the protective effect of cordycepin against the excitotoxic neuronal insult in AD using whole-cell patch clamp techniques. β-Amyloid (Aβ) and ibotenic acid (IBO)–induced injury model in cultured hippocampal neurons was used for the purpose. The results revealed that cordycepin significantly delayed Aβ + IBO–induced excessive neuronal membrane depolarization. It increased the onset time/latency, extended the duration, and reduced the slope in both slow and rapid depolarization. Additionally, cordycepin reversed the neuronal hyperactivity in Aβ + IBO–induced evoked action potential (AP) firing, including increase in repetitive firing frequency, shortening of evoked AP latency, decrease in the amplitude of fast afterhyperpolarization, and increase in membrane depolarization. Further, the suppressive effect of cordycepin against Aβ + IBO–induced excessive neuronal membrane depolarization and neuronal hyperactivity was blocked by DPCPX (8-cyclopentyl-1,3-dipropylxanthine, an adenosine A1 receptor–specific blocker). Collectively, these results revealed the suppressive effect of cordycepin against the Aβ + IBO–induced excitotoxic neuronal insult by attenuating excessive neuronal activity and membrane depolarization, and the mechanism through the activation of A1R is strongly recommended, thus highlighting the therapeutic potential of cordycepin in AD.

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