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      • KCI등재

        사례 분석을 통한 캐릭터의 법적 보호 방법에 관한 고찰 -카카오와 라인을 중심으로-

        서지원 ( Seo¸ Jiwon ),김이진 ( Kim¸ Lee Jin ) 한국기초조형학회 2021 기초조형학연구 Vol.22 No.4

        캐릭터 디자이너에게 창작물에 대한 법적 보호는 중요하다. 캐릭터의 보호에 관한 기존 연구들은 실무적인 질문에 대하여 답을 얻기에는 다소 추상적이다. 본고에서는 캐릭터 디자이너에게 실무상 효율적으로 자신의 캐릭터에 대한 보호를 추구하는 방법을 제시하고자 하였다. 이를 위하여 먼저 캐릭터를 보호하기 위한 법률을 살펴보았다. 이어서 현재 상업적으로 성공한 캐릭터의 대표적 사례로 볼 수 있는 카카오와 라인의 캐릭터를 연구 대상 사례로 선정하고 이를 분석하였다. 구체적으로, 캐릭터를 보호하기 위한 법률에는 크게 저작권법과 산업재산권 관련법인 상표법, 디자인보호법이 있다. 따라서 본 고에서는 저작권법과 상표법, 디자인보호법이 캐릭터의 어느 면을 보호하는지를 간략히 소개하였다. 그리고 저작권법, 상표법, 디자인보호법에 대한 이해를 바탕으로 카카오와 라인의 캐릭터에 대한 저작권, 상표권, 디자인권 세부 사항을 분석하고 그 내용을 소개하였다. 1)저작권의 경우, 카카오는 모든 캐릭터에 대해 저작권을 등록하였고, 라인은 두 번째 공개한 BT21은 저작권 등록을 했지만, 첫 번째 공개 캐릭터인 라인 프렌즈에서는 저작권 등록에 소극적이었다. 2)상표권은 상표 형태에 따라 여러 종류가 있는데, 본고에서는 캐릭터와 관련된 상표로 문자상표, 도형상표, 도형복합상표를 다루었다. 카카오는 첫 번째 캐릭터인 카카오 프렌즈에서는 상표 획득에 시행착오를 겪은 것으로 보이지만, 두 번째 캐릭터인 니니즈에서는 모든 캐릭터에 대해 문자상표와 도형상표를 획득하였다. 라인은 저작권 뿐 아니라 문자상표, 도형상표 출원에도 소극적인 모습을 보였지만, 모든 캐릭터에 대해 도형복합상표를 등록하였다. 3)디자인권의 경우, 카카오는 모든 캐릭터를 3차원으로 입체화시킨 인형(완구)과 화상디자인을 출원하였다. 반면 라인은 모든 캐릭터를 출원하기보다는 등록이 필요할 상품을 출원하는 전략을 택한 것으로 보인다. 이러한 분석 결과를 바탕으로 효율적인 권리 획득 전략을 제안하였다. It is important for a character designer to get legal protection of its character. Existing studies regarding protection of character are somewhat abstract to practical questions on how to obtain such legal protection and which route should be taken. This study suggested an effective method for protection of characters to designers. For this, the relevant laws for protection of charaters are first discussed. Subsequently, Kakao and Line characters, which can be seen as representative examples of commercially successful characters, were selected as the subject of study and analyzed. Specifically, laws for protection of character include the Copyright law, and the Intellectual Property laws such as the Trademark law and the Design right law. Therefore, first what aspect of characters is protected by the relevant laws are summarized here, and based on the understanding of the laws, the details of copyrights, trademarks, and designs of Kakao and Line’s characters are analyzed and the results are provided. 1)As for copyright, Kakao obtained registration of all its characters, and Line obtained registration of BT21 as its second published character group but took a passive attitude toward Line Friends as its first character group. 2)As for Trademark, several types exist, and this article addressed word mark, figurative mark, and composite trademark. Kakao seems to have undergone trial and error about its first character group, Kakao Friends, but obtained word mark and figurative mark of all characters of Niniz as its second character group. Line showed a passive attitude toward word mark and figurative mark as well as copyright, but obtained composite trademark for all its characters. 3)As for design right, Kakao filed applications of all characters by making them 3-dimentional structures while designating toy and graphic design on display panel as the products using the character. On the contrary, Line seems to have taken strategy to file applications of only the products that need registration of right, rather than obtaining of rights for all its characters. Effective strategy for obtaining rights was suggested in this article based on the analysis results above.

      • KCI등재

        태음조위탕(太陰調胃湯) 약물 가감(加減) 원리

        신승원,이지원,황민우,이준희,고병희,이의주,Shin, Seungwon,Lee, Jiwon,Hwang, Minwoo,Lee, Junhee,Koh, Byunghee,Lee, Euiju 사상체질의학회 2016 사상체질의학회지 Vol.28 No.3

        Objectives This study aimed at proposing a hypothetical principle to add or abstract herbs for modifying Taeeumjowi-tang.Method Based on Jema Lee's literatures such as Dongyisusebowon and Dongyisasangsipyeon, we analyzed contents related to Taeeumjowi-tang and its modification. Moreover, we reviewed physiological and pathological pecularities of Taeeumin symptomatology and applied the theory to induce the principle of the modified Taeeumjowi-tang in Sasang medicine.Results and Conclusions 1) We have found 10 modified Taeeumjowi-tang from Dongyisasangsipyeon. 2) Mahwangjowi-tang (麻黃調胃湯), Gogijowi-tang (固氣調胃湯), Shingijowi-tang (腎氣調胃湯), Euiyiinjowi-tang (薏苡仁調胃湯), Gamijowi-tang (加味調胃湯), and Gyeongheomjowi-tang (經驗調胃湯) are modified for Taeeumin who have original symptoms of more severe cold tendency. Especially, Gogijowi-tang helps to circulate energy-fluid from esophagus to skin, while Shingijowi-tang directly aids the function of esophagus. 3) Seungjijowi-tang (升芷調胃湯), Seunggeumjowi-tang (升芩調胃湯), Seunggijowi-tang (承氣調胃湯), and Jowisokmyung-tang (調胃續命湯) are modified for Taeeumin who have originally cold symtoms, accompanied by heat tendencies. Especially, Seungjijowi-tang helps to eliminate mild heat existing throughout skin and flesh, while Seunggeumjowi-tang gets rid of severe heat swarming in the flesh parts. Seunggijowi-tang can take away the most severe heat symptoms in the whole body

      • Optimal anesthesia protocols for successful intraoperative neuromonitoring during thyroid surgery

        Jiwon Lee(Jiwon Lee),Jung-Man Lee(Jung-Man Lee),Young Jun Chai(Young Jun Chai) 대한신경모니터링학회 2022 Journal of Neuromonitoring & Neurophysiology Vol.2 No.2

        There are several factors related to anesthesia that are required for successful intraoperative neuromonitoring (IONM) during thyroid and parathyroid surgery, including proper placement of endotracheal tube, adequate neuromuscular blockade, use of appropriate neuromuscular blockade reversal agent, and pain management. In this review, we summarize the anesthesia issues related to IONM during thyroid and parathyroid surgery.

      • KCI등재

        IntraBrain Injector (IBI): A Stereotactic-Guided Device for Repeated Delivery of Therapeutic Agents Into the Brain Parenchyma

        Jeongmin Lee,Sangwook Lee,Wooram Jung,Guk Bae Kim,Taehun Kim,Jiwon Seong,장혜민,Young Noh,Na Kyung Lee,Boo Rak Lee,Jung-Il Lee,Soo Jin Choi,Wonil Oh,Namkug Kim,Seunghoon Lee,Duk L. Na 대한의학회 2022 Journal of Korean medical science Vol.37 No.31

        Background: To deliver therapeutics into the brain, it is imperative to overcome the issue of the blood-brain-barrier (BBB). One of the ways to circumvent the BBB is to administer therapeutics directly into the brain parenchyma. To enhance the treatment efficacy for chronic neurodegenerative disorders, repeated administration to the target location is required. However, this increases the number of operations that must be performed. In this study, we developed the IntraBrain Injector (IBI), a new implantable device to repeatedly deliver therapeutics into the brain parenchyma. Methods: We designed and fabricated IBI with medical grade materials, and evaluated the efficacy and safety of IBI in 9 beagles. The trajectory of IBI to the hippocampus was simulated prior to surgery and the device was implanted using 3D-printed adaptor and surgical guides. Ferumoxytol-labeled mesenchymal stem cells (MSCs) were injected into the hippocampus via IBI, and magnetic resonance images were taken before and after the administration to analyze the accuracy of repeated injection. Results: We compared the planned vs. insertion trajectory of IBI to the hippocampus. With a similarity of 0.990 ± 0.001 (mean ± standard deviation), precise targeting of IBI was confirmed by comparing planned vs. insertion trajectories of IBI. Multiple administrations of ferumoxytol-labeled MSCs into the hippocampus using IBI were both feasible and successful (success rate of 76.7%). Safety of initial IBI implantation, repeated administration of therapeutics, and long-term implantation have all been evaluated in this study. Conclusion: Precise and repeated delivery of therapeutics into the brain parenchyma can be done without performing additional surgeries via IBI implantation.

      • KCI등재후보

        Estimating dose-response curves using splines: a nonparametric Bayesian knot selection method

        Lee, Jiwon,Kim, Yongku,Kim, Young Min The Korean Statistical Society 2022 Communications for statistical applications and me Vol.29 No.3

        In radiation epidemiology, the excess relative risk (ERR) model is used to determine the dose-response relationship. In general, the dose-response relationship for the ERR model is assumed to be linear, linear-quadratic, linear-threshold, quadratic, and so on. However, since none of these functions dominate other functions for expressing the dose-response relationship, a Bayesian semiparametric method using splines has recently been proposed. Thus, we improve the Bayesian semiparametric method for the selection of the tuning parameters for splines as the number and location of knots using a Bayesian knot selection method. Equally spaced knots cannot capture the characteristic of radiation exposed dose distribution which is highly skewed in general. Therefore, we propose a nonparametric Bayesian knot selection method based on a Dirichlet process mixture model. Inference of the spline coefficients after obtaining the number and location of knots is performed in the Bayesian framework. We apply this approach to the life span study cohort data from the radiation effects research foundation in Japan, and the results illustrate that the proposed method provides competitive curve estimates for the dose-response curve and relatively stable credible intervals for the curve.

      • KCI등재

        Adverse Reactions of the Second Dose of the BNT162b2 mRNA COVID-19 Vaccine in Healthcare Workers in Korea

        Lee Yun Woo,Lim So Yun,Lee Ji-Hyang,Lim Joon Seo,Kim Miseo,Kwon Seonhee,Joo Jiyeon,Kwak Sun Hee,Kim Eun Ok,Jung Jiwon,Kwon Hyouk-Soo,Kim Tae-Bum,Kim Sung-Han,Bae Seongman 대한의학회 2021 Journal of Korean medical science Vol.36 No.21

        We conducted a prospective, mobile-based survey on the self-reported adverse reactions in healthcare workers (HCWs) who received both doses of the BNT162b2 mRNA vaccine. Of the 342 HCWs who completed the two-dose vaccination, 265 (77.5%) responded to the survey at least once. Overall, the rates of adverse reactions were higher after the second dose compared with the first dose (89.1% vs. 80.1%, P = 0.006). The most common systemic reactions were muscle ache (69.1%), fatigue (65.7%), headache (48.7%), chills (44.2%), and fever (32.1%), and were notably more common after the second dose vaccine as well. We also noted a sex difference in which the frequency of adverse reactions after the second dose of the vaccine was significantly higher in females, which was not observed after the first dose. The rates of adverse reactions were lower in older age groups, and the rates and severities of the adverse reactions decreased during the 3-day period following vaccination.

      • SCISCIESCOPUS

        Coactivation of the CLOCK-BMAL1 complex by CBP mediates resetting of the circadian clock.

        Lee, Yool,Lee, Jiwon,Kwon, Ilmin,Nakajima, Yoshihiro,Ohmiya, Yoshihiro,Son, Gi Hoon,Lee, Kun Ho,Kim, Kyungjin Cambridge University Press 2010 Journal of cell science Vol.123 No.20

        <P>The transcription factor CLOCK-BMAL1 is a core component of the molecular clock machinery that drives circadian gene expression and physiology in mammals. Recently, we reported that this heterodimeric transcription factor functions as a signaling molecule in response to the resetting stimuli via the Ca²+-dependent protein kinase C pathway. Here, we demonstrate that the CREB-binding protein (CBP) plays a key role in rapid activation of the CLOCK-BMAL1 heterodimer that leads to phase resetting of the circadian clock. Under physiological conditions, a bimolecular fluorescence complementation (BiFC) assay revealed that CLOCK and BMAL1 dimerize in the cytoplasm and subsequently translocate into the nucleus in response to serum stimuli (mean time duration was 29.2 minutes and mean velocity 0.7 관m/minute). Concomitantly, BMAL1 rapidly recruited CBP on Per1 promoter E-box, but not p300 (a functional analog of CBP), in the discrete nuclear foci. However, recruitment of CBP by cAMP/Ca²+ response element-binding (CREB) protein on CRE was not markedly increased upon delivery of the resetting stimuli. Furthermore, overexpression of CBP greatly potentiated the CLOCK-BMAL1-mediated Per1 transcription, and this effect was completely abolished by site-directed mutation of E-box elements, but not by the mutation of CRE in the Per1 promoter. Furthermore, molecular knockdown of CBP severely dampened circadian oscillation of clock gene expression triggered by the resetting stimuli. These findings suggest that CBP recruitment by BMAL1 mediates acute transactivation of CLOCK-BMAL1, thereby inducing immediate-early Per1 transcription and phase resetting of the circadian clock.</P>

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