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ARE THE FAINT STRUCTURES AHEAD OF SOLAR CORONAL MASS EJECTIONS REAL SIGNATURES OF DRIVEN SHOCKS?
Lee, Jae-Ok,Moon, Y.-J.,Lee, Jin-Yi,Lee, Kyoung-Sun,Kim, Sujin,Lee, Kangjin IOP Publishing 2014 ASTROPHYSICAL JOURNAL LETTERS - Vol.796 No.1
<P>Recently, several studies have assumed that the faint structures ahead of coronal mass ejections (CMEs) are caused by CME-driven shocks. In this study, we have conducted a statistical investigation to determine whether or not the appearance of such faint structures depends on CME speeds. For this purpose, we use 127 Solar and Heliospheric Observatory/Large Angle Spectroscopic COronagraph (LASCO) front-side halo (partial and full) CMEs near the limb from 1997 to 2011. We classify these CMEs into two groups by visual inspection of CMEs in the LASCO-C2 field of view: Group 1 has the faint structure ahead of a CME and Group 2 does not have such a structure. We find the following results. (1) Eighty-seven CMEs belong to Group 1 and 40 CMEs belong to Group 2. (2) Group 1 events have much higher speeds (average = 1230 km s(-1) and median = 1199 km s(-1)) than Group 2 events (average = 598 km s(-1) and median = 518 km s(-1)). (3) The fraction of CMEs with faint structures strongly depends on CME speeds (V): 0.93 (50/54) for fast CMEs with V >= 1000 km s(-1), 0.65 (34/52) for intermediate CMEs with 500 km s(-1) <= V < 1000 km s(-1), and 0.14 (3/21) for slow CMEs with V < 500 km s(-1). We also find that the fraction of CMEs with deca-hecto metric type II radio bursts is consistent with the above tendency. Our results indicate that the observed faint structures ahead of fast CMEs are most likely an enhanced density manifestation of CME-driven shocks.</P>
Perturbations of gut microbiome genes in infants with atopic dermatitis according to feeding type
Lee, Min-Jung,Kang, Mi-Jin,Lee, So-Yeon,Lee, Eun,Kim, Kangjin,Won, Sungho,Suh, Dong In,Kim, Kyung Won,Sheen, Youn Ho,Ahn, Kangmo,Kim, Bong-Soo,Hong, Soo-Jong Elsevier 2018 The journal of allergy and clinical immunology Vol.141 No.4
<P><B>Background</B></P> <P>Perturbations of the infant gut microbiota can shape development of the immune system and link to the risk of allergic diseases.</P> <P><B>Objective</B></P> <P>We sought to understand the role of the gut microbiome in patients with atopic dermatitis (AD). The metagenome of the infant gut microbiome was analyzed according to feeding types.</P> <P><B>Methods</B></P> <P>Composition of the gut microbiota was analyzed in fecal samples from 129 infants (6 months old) by using pyrosequencing, including 66 healthy infants and 63 infants with AD. The functional profile of the gut microbiome was analyzed by means of whole-metagenome sequencing (20 control subjects and 20 patients with AD). In addition, the total number of bacteria in the feces was determined by using real-time PCR.</P> <P><B>Results</B></P> <P>The gut microbiome of 6-month-old infants was different based on feeding types, and 2 microbiota groups (<I>Bifidobacterium</I> species–dominated and <I>Escherichia/Veillonella</I> species–dominated groups) were found in breast-fed and mixed-fed infants. Bacterial cell amounts in the feces were lower in infants with AD than in control infants. Although no specific taxa directly correlated with AD in 16S rRNA gene results, whole-metagenome analysis revealed differences in functional genes related to immune development. The reduction in genes for oxidative phosphorylation, phosphatidylinositol 3-kinase–Akt signaling, estrogen signaling, nucleotide-binding domain–like receptor signaling, and antigen processing and presentation induced by reduced colonization of mucin-degrading bacteria (<I>Akkermansia muciniphila</I>, <I>Ruminococcus gnavus</I>, and <I>Lachnospiraceae</I> bacterium 2_1_58FAA) was significantly associated with stunted immune development in the AD group compared with the control group (<I>P</I> < .05).</P> <P><B>Conclusions</B></P> <P>Alterations in the gut microbiome can be associated with AD because of different bacterial genes that can modulate host immune cell function.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Kim Kangjin,Lee Sanghun,Park Sang-Chul,Kim Nam-Eun,Shin Chol,Lee Seung Ku,Jung Youngae,Yoon Dankyu,Kim Hyeonjeong,Kim Sanghyun,Hwang Geum-Sook,Won Sungho 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-
Recent investigations have revealed that the human microbiome plays an essential role in the occurrence of type 2 diabetes (T2D). However, despite the importance of understanding the involvement of the microbiota throughout the body in T2D, most studies have focused specifically on the intestinal microbiota. Extracellular vesicles (EVs) have been recently found to provide important evidence regarding the mechanisms of T2D pathogenesis, as they act as key messengers between intestinal microorganisms and the host. Herein, we explored microorganisms potentially associated with T2D by tracking changes in microbiota-derived EVs from patient urine samples collected three times over four years. Mendelian randomization analysis was conducted to evaluate the causal relationships among microbial organisms, metabolites, and clinical measurements to provide a comprehensive view of how microbiota can influence T2D. We also analyzed EV-derived metagenomic (N = 393), clinical (N = 5032), genomic (N = 8842), and metabolite (N = 574) data from a prospective longitudinal Korean community-based cohort. Our data revealed that GU174097_g, an unclassified Lachnospiraceae, was associated with T2D (β = −189.13; p = 0.00006), and it was associated with the ketone bodies acetoacetate and 3-hydroxybutyrate (r = −0.0938 and −0.0829, respectively; p = 0.0022 and 0.0069, respectively). Furthermore, a causal relationship was identified between acetoacetate and HbA1c levels (β = 0.0002; p = 0.0154). GU174097_g reduced ketone body levels, thus decreasing HbA1c levels and the risk of T2D. Taken together, our findings indicate that GU174097_g may lower the risk of T2D by reducing ketone body levels.
중년여성의 가족스트레스와 삶의 의미와의 관계에서 자기성찰지능의 매개효과
이강진(Lee, KangJin),김영희(Kim, YeongHee) 학습자중심교과교육학회 2018 학습자중심교과교육연구 Vol.18 No.7
본 연구는 중년기 여성의 가족스트레스, 삶의 의미, 자기성찰지능간의 관계를 알아보고 가족스트레스와 삶의 의미의 관계에서 자기성찰지능의 매개효과를 검증하고자 하였다. 이를 위해 2017년 9월 1일부터 9월 22일까지 총 22일 간에 걸쳐 서울, 경 지지역의 40세에서 60세 사이의 중년여성을 대상으로 가족스트레스, 삶의 의미, 자기성찰지능 척도로 구성된 설문을 실시하여 수집된 자료 451부를 분석에 사용하였다. SPSS 21.0을 사용하여 기술통계 및 상관분석을 실시하였으며, 자기성찰지능의 매개효과를 검증하기 위해 위계적 회귀분석과 Sobel test를 실시하였다. 그 결과 첫째, 중년기 여성의 가족스트레스는 삶의 의미와 유의한 부적상관을, 자기성찰지능과도 유의한 부적상관을 보였다. 또한 삶의 의미는 자기성찰지능과 유의한 정적 상관 이 있는 것으로 나타났다. 둘째, 중년여성의 가족스트레스와 삶의 의미와의 관계에 있어서 자기성찰지능은 완전매개효과가, 가족스트레스와 삶의 의미와의 관계에서 자기성찰지능의 하위요인인 자기이해, 자기설계는 완전매개효과가, 자기반성과는 부 분매개효과가 있었다. 이러한 결과는 가족스트레스를 경험하는 중년여성에게 자아성찰지능은 삶의 의미를 향상시키는 완충작용 변인임을 밝혔다는 의의가 있다. The purpose of this study was to investigate mediating effects of intrapersonal intelligence between family stress and meaning of life of middle aged women. For this purpose during 22 days from 1st of Sep to 22nd of Sep 2017, the subjects were 451 middle aged woman aged 40 to 60 years lived in Seoul and Gyeong-gi province. Three measurements were employed : the family stress scale, the intrapersonal intelligence scale and the meaning of life scale. The collected data were analyzed by descriptive statistical analysis and Pearson correlation analysis, mediation analysis of Baron and Kenny(1986), and sobel test using SPSS 21.0 program to verify the significance of the mediation path. The results showed as follows: First, family stress of middle aged woman showed significant negative correlations with both meaning of life and intrapersonal intelligence, and meaning of life showed significant positive correlations with intrapersonal intelligence. Second, intrapersonal intelligence completely mediated the relationship between family stress and meaning of life of middle aged women. Self-examination and self-designing, sub-factor derived from intrapersonal intelligence, had full mediating effect on Relations between family stresses and meaning of life, on the other hand, self-reflection had partial mediating effect. Such results signify that middle aged women experiencing family stress can absorb and improve meaning of life with the factor of intrapersonal intelligence.
서비스러닝 참여 대학생의 노인이미지 변화에 관한 포토보이스 연구
이강진(Kangjin Lee),전희정(Heejeong Jeon) 한국사회복지교육협의회 2022 한국사회복지교육 Vol.60 No.-
본 논문은 서비스러닝의 교육의 일환으로 지역사회 노인서비스를 진행한 대학생들을 대상으로 노인에 대한 인식이 어떻게 변화했는지를 살펴보는데 목적이 있다. 이를 위해 2022년도 1학기 국내 Y대학교의 서비스러닝 수강생 중 연구 참여 동의를 얻은 19명을 대상으로 노인 이미지에 대한 포토보이스 참여연구를 진행하였다. 연구 결과, 4개의 대주제와 15개의 하위주제가 도출되었다. 지역사회 서비스에 참여하기 전 노인은 소통하기도 어렵고 다 쓰고 남겨진 어둡고 쓸쓸한 존재로서 도움이 필요한 ‘부정과 동정의 존재’였다. 그러나, 지역사회 서비스에 참여함으로써 새로운 경험, 새로운 인식, 새로운 관점을 형성하게 되고, 노인과의 ‘관계를 통해 성찰하고 배워’나갈 수 있다. 이러한 서비스러닝은 노인을 경험과 연륜이 쌓인 지혜로운 존재, 강한 생명력과 든든한 존재, 여전히 활기찬 인생을 살고 있고 사회에 도움이 되고 싶어하는 따뜻하고 ‘포용적 존재로 재탄생’시켰다. 서비스러닝 경험을 통해 학생들은 노인들을 위한 새로운 역할을 찾아내고 지속적인 관심과 소통을 통해 노인을 여전히 하나의 사회구성원으로 ‘우리 안에 포함하는 것’이 실천의 모습이라고 밝혔다. 이러한 결과를 바탕으로 지역사회 노인에 대한 서비스러닝 교육의 의의와 인식개선을 위한 제언을 하였다.