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Dynamic Analysis of Francis Runners - Experiment and Numerical Simulation
Lais, Stefan,Liang, Quanwei,Henggeler, Urs,Weiss, Thomas,Escaler, Xavier,Egusquiza, Eduard Korean Society for Fluid machinery 2009 International journal of fluid machinery and syste Vol.2 No.4
The present paper shows the results of numerical and experimental modal analyses of Francis runners, which were executed in air and in still water. In its first part this paper is focused on the numerical prediction of the model parameters by means of FEM and the validation of the FEM method. Influences of different geometries on modal parameters and frequency reduction ratio (FRR), which is the ratio of the natural frequencies in water and the corresponding natural frequencies in air, are investigated for two different runners, one prototype and one model runner. The results of the analyses indicate very good agreement between experiment and simulation. Particularly the frequency reduction ratios derived from simulation are found to agree very well with the values derived from experiment. In order to identify sensitivity of the structural properties several parameters such as material properties, different model scale and different hub geometries are numerically investigated. In its second part, a harmonic response analysis is shown for a Francis runner by applying the time dependent pressure distribution resulting from an unsteady CFD simulation to the mechanical structure. Thus, the data gained by modern CFD simulation are being fully utilized for the structural design based on life time analysis. With this new approach a more precise prediction of turbine loading and its effect on turbine life cycle is possible allowing better turbine designs to be developed.
( Lucia Leite Lais ),( Sancha Helena De Lima Vale ),( Camila Alves Xavier ),( Alfredo De Araujo Silva ),( Tolunay Beker Aydemir ),( Robert J Cousins ) 한국임상영양학회 2016 Clinical Nutrition Research Vol.5 No.1
To evaluate the effect of diet on metabolic control and zinc metabolism in patients with type 2 diabetes mellitus (T2DM). One-week balanced diet was provided to 10 Brazilians patients with T2DM. Nutritional assessment, laboratorial parameters and expression of zinc transporter and inflammatory genes in peripheral blood mononuclear cells (PBMC) were performed. Healthy non-diabetic subjects of the same demographic were recruited to provide baseline data. Diabetic patients had higher body mass index and greater fasting plasma glucose, plasma tumor necrosis factor α (TNFα) and plasma interleukin 6 (IL6) levels compared with healthy subjects. In addition, the expression of transporters 4 (ZnT4) mRNA was lower and IL6 mRNA was higher in PBMC of these diabetic patients than in healthy subject. One week after a balanced diet was provided, fasting plasma glucose decreased significantly as did TNFα, IL6 and Metallothionein 1 (MT1) mRNAs. No change was observed in zinc transporter expression in PBMC after the dietary intervention. A healthy eating pattern maintained for one week was able to improve metabolic control of diabetic patients by lowering fasting plasma glucose. This metabolic control may be related to down-regulation of zinc-related transcripts from PBMCs, as TNFα, IL6 and MT1 mRNA.
Gravena, Angela Andreia Franca,Brischiliari, Sheila Cristina Rocha,Gil, Lais Moraes,Lopes, Tiara Cristina Romeiro,Demitto, Marcela De Oliveira,Agnolo, Catia Millene Dell,Borghesan, Deise Helena Pellos Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23
Background: The purpose of the article was to analyze the years of potential life lost (YPLL) of women who died from breast and cervical cancer in the State of Paran$\acute{a}$, Southern Brazil. This was a temporal trend study (2000 to 2010) about the coefficients of mortality and the years of potential life lost in women aged 20 to 70 years. Materials and Methods: Data were obtained through the database of the Department of the Unified Health System (DATASUS) and the National Mortality Information System. Results: There was a loss of 125.075 YPLL due to breast cancer, with an average of 11.370 YPLL. Regarding cervical cancer, the figure obtained was 91.625 YPLL from 2000 to 2010, with an average of 8.329 YPLL. Increased risk of death from breast cancer was observed for women aged 50 to 59 years, with a significant increase among those in the age group from 40 to 49 years. There was an increased rate of cervical cancer among women 40 to 69 years. Conclusions: The risk of death grows with increasing age, being higher from 40 years. Prevention is paramount for both cancers. Thus, preventive measures are required and a reassessment of political strategies should be adopted.
( Jaquelini Betta Canever ),( Rafael Inácio Barbosa ),( Ketlyn Germann Hendler ),( Lais Mara Siqueira Das Neves ),( Heloyse Uliam Kuriki ),( Aderbal Silva Aguiar Júnior ),( Marisa De Cassia Registro F 대한통증학회 2021 The Korean Journal of Pain Vol.34 No.3
Background: Complex regional pain syndrome type I (CRPS-I) consists of disorders caused by spontaneous pain or induced by some stimulus. The objective was to verify the effects of photobiomodulation (PBM) using 830 nm wavelength light at the affected paw and involved spinal cord segments during the warm or acute phase. Methods: Fifty-six mice were randomized into seven groups. Group (G) 1 was the placebo group; G2 and G3 were treated with PBM on the paw in the warm and acute phase, respectively; G4 and G5 treated with PBM on involved spinal cord segments in the warm and acute phase, respectively; G6 and G7 treated with PBM on paw and involved spinal cord segments in the warm and acute phase, respectively. Edema degree, thermal and mechanical hyperalgesia, skin temperature, and functional quality of gait (Sciatic Static Index [SSI] and Sciatic Functional Index [SFI]) were evaluated. Results: Edema was lower in G3 and G7, and these were the only groups to return to baseline values at the end of treatment. For thermal hyperalgesia only G3 and G5 returned to baseline values. Regarding mechanical hyperalgesia, the groups did not show significant differences. Thermography showed increased temperature in all groups on the seventh day. In SSI and SFI assessment, G3 and G7 showed lower values when compared to G1, respectively. Conclusions: PBM irradiation in the acute phase and in the affected paw showed better results in reducing edema, thermal and mechanical hyperalgesia, and in improving gait quality, demonstrating efficacy in treatment of CRPS-I symptoms.
Cintia Tarabal Oliveira,Debora Romualdo Lacerda,Marina Campos Zicker,Lais Bhering Martins,Mauro Martins Teixeira,Raquel Linhares Bello de Araujo,Adaliene Versiani Matos Ferreira 한국식품영양과학회 2019 Journal of medicinal food Vol.22 No.1
This study aimed to evaluate the effects and the mechanisms of ginger extract intake in the adiposity gain, metabolic and inflammatory disturbances induced by a high-refined carbohydrate (HC) diet in mice. Ginger extract at doses of 200, 600, and 1800 mg/kg was supplemented in the daily food of obese Balb/c mice during an 8-week experiment. Our findings indicate that consumption of high doses of ginger extracts prevents the increase of adiposity induced by HC diet, improves lipid profile, and promotes decrease of inflammatory markers in mice. We showed that ginger addition to HC diet leads to decrease in the recruitment of cells visualized in vivo in the microvasculature of adipose tissue, decrease of inflammatory cytokines, and increase of adiponectin serum levels. These results indicate that the consumption of ginger decreases the negative metabolic consequences induced by HC diet.
Bacterial Postbiotics as Promising Tools to Mitigate Cardiometabolic Diseases
Anhê Fernando F.,Jensen Benjamin A. H.,Perazza Lais Rossi,Tchernof André,Schertzer Jonathan D.,Marette André 한국지질동맥경화학회 2021 지질·동맥경화학회지 Vol.10 No.2
Gut microbes dictate critical features of host immunometabolism. Certain bacterial components and metabolites (termed postbiotics) mitigate cardiometabolic diseases whereas others potentiate pathological processes. In this review, we discuss key aspects related to the usefulness of bacterial-related molecules strategically positioned as promising treatment strategies for cardiometabolic diseases.
Influence of polishing systems on roughness and color change of two dental ceramics
Lucas Campagnaro Maciel,Carlos Frederico Bettcher Silva,Ricardo Huver de Jesus,Lais Regiane da Silva Concilio,Stefania Carvalho Kano,Anuar Antonio Xible 대한치과보철학회 2019 The Journal of Advanced Prosthodontics Vol.11 No.4
PURPOSE. To evaluate the polishing effect on roughness and color change of pressed and layering ceramics after immersion in coffee solution. MATERIALS AND METHODS. 88 ceramic discs (1.0 mm × 10.0 mm) were manufactured - 44 nano-fluorapatite layering ceramics (IPS e.max Ceram. Group C) and 44 pressed lithium disilicate ceramic discs (IPS e. max Press - Group P). Each group was divided into 4 subgroups according to surface treatments: (G) Glaze, (S) Shofu polishing system (Shofu Inc.), (E) Edenta AG polishing System, (KG) 30-μm diamond granulation tip. Surface roughness (Ra) and color change (ΔE) measurings after the surface treatments were performed, before and 12 days after the immersion in coffee solution. A samples’ qualitative analysis was conducted with a scanning electron microscopy (SEM). Data were statistically-treated with oneway-ANOVA and Duncan’s tests, apart from paired t-test and Pearson’s correlation test (α=5%). RESULTS. The decrescent order, both for surface roughness (Ra) and ΔE for both ceramics were: KG > E > S > G (P<.05). With exception for PG and CG subgroups, which did not present statistical difference between them, all other pressed ceramics subgroups presented smaller Ra values and greater ΔE values than the layering ceramics subgroups (P<.05). CONCLUSION. Although mechanical polishing systems presented intermediate Ra values, their colors were considered clinically acceptable. There is a strong correlation between the surface roughness and the color change of tested ceramics.
Ana Paula Barbosa Lima,Rafael Pino Vitti,Marina Amaral,Ana Christina Claro Neves,Lais Regiane da Silva Concilio 대한치과보철학회 2018 The Journal of Advanced Prosthodontics Vol.10 No.2
PURPOSE. This study evaluated the dimensional stability of a complete-arch prosthesis processed by conventional method in water bath or microwave energy and polymerized by two different curing cycles. MATERIALS AND METHODS. Forty maxillary complete-arch prostheses were randomly divided into four groups (n = 10): MW1 - acrylic resin cured by one microwave cycle; MW2 - acrylic resin cured by two microwave cycles: WB1 - conventional acrylic resin polymerized using one curing cycle in a water bath; WB2 - conventional acrylic resin polymerized using two curing cycles in a water bath. For evaluation of dimensional stability, occlusal vertical dimension (OVD) and area of contact points were measured in two different measurement times: before and after the polymerization method. A digital caliper was used for OVD measurement. Occlusal contact registration strips were used between maxillary and mandibular dentures to measure the contact points. The images were measured using the software IpWin32, and the differences before and after the polymerization methods were calculated. The data were statistically analyzed using the one-way ANOVA and Tukey test (α = .05). RESULTS. The results demonstrated significant statistical differences for OVD between different measurement times for all groups. MW1 presented the highest OVD values, while WB2 had the lowest OVD values (P<.05). No statistical differences were found for area of contact points among the groups (P=.7150). CONCLUSION. The conventional acrylic resin polymerized using two curing cycles in a water bath led to less difference in OVD of complete-arch prosthesis.
Lai, S.,Park, J.,Cho, S.,Tsai, M.,Lim, H.,Chen, K. Pergamon Press ; Elsevier Science Ltd 2016 INTERNATIONAL JOURNAL OF HYDROGEN ENERGY - Vol.41 No.22
<P>The ultra-thin cross-linked PBI membrane containing phosphoric acid (PA) for possible use in a fuel cell was prepared by electron beam irradiation method. The preparation procedure involved two steps: (a) irradiation of PBI membranes (PBI-1, PBI-2 and PBI-3) by an electron beam with increased dose energy and (b) doping the irradiated membranes with PA. These membranes were characterized in terms of mechanical properties, chemical and thermal stability were evaluated using Universal Testing machine, Ultraviolet visible spectroscopy and thermogravimetric analysis, respectively. Compared to the pristine PBI membrane of thickness 20 gm, the cross-linked PBI membranes show much better mechanical properties and improved chemical and thermal stability. In addition, the tensile strength of the cross-linked PBI membranes with PA ranges from 19 MPa to 27 MPa, which is higher than that of the pristine PBI membrane with PA (14 MPa). Besides these, the fuel cell performance of the PBI-1 is similar to that of the pristine PBI membrane of thickness 20 gm, but higher than common used PBI membrane of thickness 40 gm. The overall results suggest that the membrane has a great potential for possible application in high temperature PEM fuel cell. (C) 2016 Hydrogen Energy Publications LLC. Published by Elsevier Ltd. All rights reserved.</P>