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1
External electric field induced hydrogen storage/release on calcium-decorated single-layer and bilayer silicene

Song, Er Hong,Yoo, Sung Ho,Kim, Jae Joon,Lai, Shiau Wu,Jiang, Qing,Cho, Sung Oh The Royal Society of Chemistry 2014 Physical chemistry chemical physics Vol.16 No.43
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Hydrogen storage and release are two essential parameters that define the efficiency of a hydrogen storage medium. Herein, we investigate the effects of the external electric field F on the adsorption–desorption of H2 on a Ca-decorated silicene system (Ca–silicene) based on density functional theory calculations. Our study demonstrates that nine H2 molecules per Ca atom can be adsorbed and 6.4 wt% H2 can be adsorbed on Ca–silicene with an average binding energy of 0.19 eV per H2, while the appropriate F can be used to effectively enhance the hydrogen storage–release on the Ca–silicene system. The high synergetic effect may be attributed to the observation that F induces an enhancement of the charge transfer between H2 molecules and the Ca–silicene system. Thus, the Ca–silicene system together with the synergy of F can efficiently facilitate H2 adsorption–desorption, completing the whole hydrogen storage–release cycle. Graphic AbstractThe appropriate F can be used to effectively enhance the hydrogen storage–release on the Ca–silicene system. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c4cp02638a'>
2
Apple RING finger E3 ubiquitin ligase MdMIEL1 negatively regulates salt and oxidative stresses tolerance

Jian-Ping An,Xin Liu,Lai-Qing Song,Chun-Xiang You,Xiao-Fei Wang,Yu-Jin Hao 한국식물학회 2017 Journal of Plant Biology Vol.60 No.2
RING-finger-containing E3 ubiquitin ligases play important roles in plant response to biotic and abiotoc stresses. In this study, through homology analysis, a Malus× domestica MYB30-Interacting E3 Ligase 1 gene, MdMIEL1, was identified and subsequently cloned from apple ‘Gala’ (Malus×domestica). MdMIEL1 contained a zinc finger domain close to N-terminus and a RING finger domain close to Cterminus. Expression of MdMIEL1 was significantly induced by NaCl and H2O2 treatments. Further study demonstrated that the MdMIEL1-overexpressing Arabidopsis and apple calli were less tolerance to salt stress than wild-type control. In addition, transgenic plants had higher levels of reactive oxygen species (ROS) (H2O2 and O2 –). And transgenic Arabidopsis and apple calli exhibited more sensitive phenotype to H2O2 treatment, which was associated with increased levels of ROS. These findings indicate MdMIEL1 is an important regulator involved in plant response to salt and oxidative stresses tolerance.
3
Drug therapy and monitoring for inflammatory bowel disease: a multinational questionnaire investigation in Asia

( Chenwen Cai ),( Juntao Lu ),( Lijie Lai ),( Dongjuan Song ),( Jun Shen ),( Jinlu Tong ),( Qing Zheng ),( Kaichun Wu ),( Jiaming Qian ),( Zhihua Ran ) 대한장연구학회 2022 Intestinal Research Vol.20 No.2
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- 복사/대출신청
Background/Aims: The incidence and prevalence of inflammatory bowel disease (IBD) is rising in Asia recently. The study aimed to obtain a comprehensive understanding of the current status of drug therapy and monitoring for IBD in Asia. Methods: A questionnaire investigation on drug therapy and monitoring for IBD was conducted right before the 6th Annual Meeting of Asian Organization for Crohn’s & Colitis. Questionnaires were provided to Asian physicians to fill out via emails between March and May 2018. Results: In total, responses of 166 physicians from 129 medical centers were included for analysis. Among the surveyed regions, the most average number of IBD specialist gastroenterologists and nurses was 4.8 per center in Taiwan and 2.5 per center in Mainland China, respectively. 5-Aminosalicylic acid/sulfasalazine (99.4%) was the most preferred first-line choice for mild-moderate ulcerative colitis (UC), meanwhile corticosteroid (83.7%) was widely applied for severe UC. The first-line medication for Crohn’s disease (CD) markedly varied as corticosteroid (68.1%) was the most favored in Mainland China, Japan, and South Korea, followed by infliximab (52.4%) and azathioprine (47.0%). Step-up strategy was preferred in mild-moderate UC (96.4%), while 51.8% of the physicians selected top-down treatment for CD. Only 25.9% and 17.5% of the physicians could test blood concentration of infliximab and antibody to infliximab in their hospitals, respectively. Conclusions: The current status of drug therapy and monitoring for IBD in Asia possesses commonalities as well as differences. Asian recommendations, IBD specialist teams and practice of therapeutic drug monitoring are required to improve IBD management in Asia. (Intest Res 2022;20:213-223)