Serpentine Microstrip Lines With Zero Far-End Crosstalk for Parallel High-Speed DRAM Interfaces

Kyoungho Lee,Hae-Kang Jung,Hyung-Joon Chi,Hye-Jung Kwon,Jae-Yoon Sim,Hong-June Park IEEE 2010 IEEE TRANSACTIONS ON ADVANCED PACKAGING Vol.33 No.2

<P>Serpentine microstrip lines are proposed to eliminate the far-end crosstalk in parallel high-speed interfaces by increasing the capacitive coupling ratio to equal the inductive coupling ratio. Zero far-end crosstalk voltage waveform and zero crosstalk-induced jitter (CIJ) were achieved on an FR4 printed circuit board, by adjusting the unit section length of the serpentine structure. Application of the proposed serpentine microstrip lines to the 2-drop stub series terminated logic DRAM channel increased the maximum data rate from 0.9 to 1.4 Gb/s and reduced CIJ by ~ 78 ps at 3.3 Gb/s.</P>

TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: a critical role of IFN-beta as a decision maker.

Jung, Dae Young,Lee, Heasuk,Jung, Bo-Young,Ock, Jiyeon,Lee, Myung-Shik,Lee, Won-Ha,Suk, Kyoungho American Association of Immunologists 2005 Journal of Immunology Vol.174 No.10

<P>TLRs mediate diverse signaling after recognition of evolutionary conserved pathogen-associated molecular patterns such as LPS and lipopeptides. Both TLR2 and TLR4 are known to trigger a protective immune response as well as cellular apoptosis. In this study, we present evidence that TLR4, but not TLR2, mediates an autoregulatory apoptosis of activated microglia. Brain microglia underwent apoptosis upon stimulation with TLR4 ligand (LPS), but not TLR2 ligands (Pam(3)Cys-Ser-Lys(4), peptidoglycan, and lipoteichoic acid). Based on studies using TLR2-deficient or TLR4 mutant mice and TLR dominant-negative mutants, we also demonstrated that TLR4, but not TLR2, is necessary for microglial apoptosis. The critical difference between TLR2 and TLR4 signalings in microglia was IFN regulatory factor-3 (IRF-3) activation, followed by IFN-beta expression: while TLR4 agonist induced the activation of IRF-3/IFN-beta pathway, TLR2 did not. Nevertheless, both TLR2 and TLR4 agonists strongly induced NF-kappaB activation and NO production in microglia. Neutralizing Ab against IFN-beta attenuated TLR4-mediated microglial apoptosis. IFN-beta alone, however, did not induce a significant cell death. Meanwhile, TLR2 activation induced microglial apoptosis with help of IFN-beta, indicating that IFN-beta production following IRF-3 activation determines the apoptogenic action of TLR signaling. TLR4-mediated microglial apoptosis was mediated by MyD88 and Toll/IL-1R domain-containing adaptor-inducing IFN-beta, and was associated with caspase-11 and -3 activation rather than Fas-associated death domain protein/caspase-8 pathway. Taken together, TLR4 appears to signal a microglial apoptosis via autocrine/paracrine IFN-beta production, which may act as an apoptotic sensitizer.</P>

Graphene Electrodes for Artificial Muscles

Min, Kyoungho,Jung, Ji Young,Han, Tae Hee,Park, Younduk,Jung, Cheolsoo,Hong, Soon Man,Koo, Chong Min Informa UK (TaylorFrancis) 2011 MOLECULAR CRYSTALS AND LIQUID CRYSTALS - Vol.539 No.1

A Serpentine Guard Trace to Reduce the Far-End Crosstalk Voltage and the Crosstalk Induced Timing Jitter of Parallel Microstrip Lines

Kyoungho Lee,Hyun-Bae Lee,Hae-Kang Jung,Jae-Yoon Sim,Hong-June Park IEEE 2008 IEEE TRANSACTIONS ON ADVANCED PACKAGING Vol.31 No.4

<P>A serpentine guard trace is proposed to reduce the peak far-end crosstalk voltage and the crosstalk induced timing jitter of parallel microstrip lines on printed circuit boards. The vertical sections of the serpentine guard increase the mutual capacitance without much changing the mutual inductance between the aggressor and victim lines. This reduces the difference between the capacitive and inductive couplings and hence the far-end crosstalk. Comparison with the no guard, the conventional guard, and the via-stitch guard shows that the serpentine guard gives the smallest values in both the peak far-end crosstalk voltage and the timing jitter. The time domain reflectometer (TDR) measurement shows that the peak far-end crosstalk voltage of serpentine guard is reduced to 44% of that of no guard. The eye diagram measurement of pseudo random binary sequence (PRBS) data shows that the timing jitter is also reduced to 40% of that of no guard.</P>

Immediate effect of self-myofascial release on hamstring flexibility

Jung, Jihye,Choi, Wonjae,Lee, Yonghyuk,Kim, Jiwoo,Kim, Hyunju,Lee, Kyoungho,Lee, Jaewoo,Lee, Seungwon korean Academy of Physical Therapy Rehabilitation 2017 Physical therapy rehabilitation science Vol.6 No.1

Objective: This study aimed to identify the area with greatest effect using self-myofascial release technique (self-MFR) in the hamstring, suboccipital, and plantar regions. Design: Cross-sectional study. Methods: Twenty-two adult subjects were evaluated for flexibility and hamstring pain threshold after self-MFR. Based on the superficial back line, the self-MFR application areas were the suboccipital region, hamstring, and plantar regions. Self-MFR was applied to each area using a wooden pole for a total of 4 minutes. Self-MFR was applied for 3 days at the same time of day, which was randomly assigned for each subject. Treatment was applied to one area each day. The sit and reach test (SRT), active range of motion (AROM), and passive ROM (PROM) were used to determine changes in flexibility, and an algometer was used to determine pain threshold. Pre/post-self-MFR effectiveness was tested using a paired t-test. Repeated measurement was used to compare self-MFR effects in the suboccipital, hamstring, and plantar regions. Results: When the self-MFR technique was applied to the 3 areas, the SRT showed significant improvement over baseline (p<0.05). Bilateral AROM and PROM showed significant improvements (p<0.05). When the self-MFR technique was applied to the hamstring, the semimembranosus showed a significant change in pain threshold (p<0.05). Conclusions: Our findings suggest that indirect application based on the Anatomy Trains could be effective for those who need to improve muscle flexibility. Moreover, self-MFR easily alleviates myofascial pain while maintaining flexibility, and can be performed at any time and place.

Pro-apoptotic activity of N-myc in activation-induced cell death of microglia

Jung, Dae Young,Lee, Heasuk,Suk, Kyoungho Blackwell Science Ltd 2005 Journal of Neurochemistry Vol.94 No.1

<P>Abstract</P><P>Brain microglial cells are thought to undergo apoptosis following the exposure to inflammatory stimuli such as lipopolysaccharide (LPS) and IFN&ggr;, which is considered as an autoregulatory mechanism to control their own activation state. Here, we report that N-myc constitutes a novel apoptotic pathway of LPS/IFN&ggr;-activated microglia. The expression of N-myc was synergistically enhanced by LPS and IFN&ggr; in microglia. Tetracycline-based conditional expression of N-myc sensitized microglia to nitric oxide (NO)-induced apoptosis. Knockdown of N-myc expression using small interfering RNA (siRNA) attenuated LPS/IFN&ggr;-induced microglial apoptosis. An increase in N-myc expression, however, did not affect microglial production of NO or TNF&agr;. The synergistic effect of LPS/IFN&ggr; on the microglial N-myc induction was mediated through Janus kinase (JAK)/STAT1 (signal transducer and activator of transcription 1) pathway. Taken together, LPS/IFN&ggr;-induced N-myc participated in the activation-induced cell death of microglia by sensitizing the cells to NO-induced apoptosis; however, N-myc did not influence the processes of inflammatory activation of microglia.</P>

Recurrent Neural Network를 이용한 영문 품사 태깅

최경호(Kyoungho Choi),이창기(Changki Lee),이청재(Cheongjae Lee),장정호(Jeongho Chang),정상근(Sangkeun Jung) 한국정보과학회 2015 한국정보과학회 학술발표논문집 Vol.2015 No.6

Immediate effect of self-myofascial release on hamstring flexibility

( Jihye Jung ),( Wonjae Choi ),( Yonghyuk Lee ),( Jiwoo Kim ),( Hyunju Kim ),( Kyoungho Lee ),( Jaewoo Lee ),( Seungwon Lee ) 물리치료재활과학회 2017 Physical therapy rehabilitation science Vol.6 No.1

Objective: This study aimed to identify the area with greatest effect using self-myofascial release technique (self-MFR) in the hamstring, suboccipital, and plantar regions. Design: Cross-sectional study. Methods: Twenty-two adult subjects were evaluated for flexibility and hamstring pain threshold after self-MFR. Based on the superficial back line, the self-MFR application areas were the suboccipital region, hamstring, and plantar regions. Self-MFR was applied to each area using a wooden pole for a total of 4 minutes. Self-MFR was applied for 3 days at the same time of day, which was randomly assigned for each subject. Treatment was applied to one area each day. The sit and reach test (SRT), active range of motion (AROM), and passive ROM (PROM) were used to determine changes in flexibility, and an algometer was used to determine pain threshold. Pre/post-self-MFR effectiveness was tested using a paired t-test. Repeated measurement was used to compare self-MFR effects in the suboccipital, hamstring, and plantar regions. Results: When the self-MFR technique was applied to the 3 areas, the SRT showed significant improvement over baseline (p<0.05). Bilateral AROM and PROM showed significant improvements (p<0.05). When the self-MFR technique was applied to the hamstring, the semimembranosus showed a significant change in pain threshold (p<0.05). Conclusions: Our findings suggest that indirect application based on the Anatomy Trains could be effective for those who need to improve muscle flexibility. Moreover, self-MFR easily alleviates myofascial pain while maintaining flexibility, and can be performed at any time and place.

가공제품에 대한 생활주변방사선 실태조사 자료를 활용한 통계분석

최경호(Kyoungho Choi),조정근(Jung Keun Cho) 대한방사선과학회(구 대한방사선기술학회) 2020 방사선기술과학 Vol.43 No.2

Radiation Following the 2011 Fukushima nuclear accident in Japan, public interest and anxiety about radiation safety increased, and vague anxiety about commonly exposed living radiation was generated. The Atomic Energy Safety Commission has been conducting a survey of processed products that advertise “negative ions” and “far-nfrared” emissions under the Living Radiation Safety Management Act. In this study, in-depth analysis was performed from a statistical point of view using the measurement data presented in the Nuclear Safety Committee s actual survey analysis report as secondary data. As a result, there was a statistically significant difference (p<0.005) between latex and civil affairs products. There were also statistically significant differences (p<0.05) in the results of testing whether there were significant differences in the annual exposure dose between groups after categorizing 71 civil products, including radon beds, into bed, bedding, and living and other categories. The correlation analysis results also confirm that, as is commonly known, the annual doses received from processed products are associated with radon derived from U-238 and Th-232.

Decursin inhibits induction of inflammatory mediators by blocking nuclear factor-kappaB activation in macrophages.

Kim, Jung-Hee,Jeong, Ji-Hye,Jeon, Sung-Tak,Kim, Ho,Ock, Jiyeon,Suk, Kyoungho,Kim, Sang-In,Song, Kyung-Sik,Lee, Won-Ha American Society for Pharmacology and Experimental 2006 Molecular pharmacology Vol.69 No.6

<P>In the course of screening inhibitors of matrix metalloproteinase (MMP)-9 induction in macrophages, we isolated decursin, a coumarin compound, from the roots of Angelicae gigas. As a marker for the screening and isolation, we tested expression of MMP-9 in RAW264.7 cells and THP-1 cells after treatment with bacterial lipopolysaccharide (LPS), the TLR-4 ligand. Decursin suppressed MMP-9 expression in cells stimulated by LPS in a dose-dependent manner at concentrations below 60 microM with no sign of cytotoxicity. The suppressive effect of decursin was observed not only in cells stimulated with ligands for TLR4, TLR2, TLR3, and TLR9 but also in cells stimulated with interleukin (IL)-1beta, and tumor necrosis factor (TNF)-alpha, indicating that the molecular target of decursin is common signaling molecules induced by these stimulants. In addition to the suppression of MMP-9 expression, decursin blocked nitric oxide production and cytokine (IL-8, MCP-1, IL-1beta, and TNF-alpha) secretion induced by LPS. To find out the molecular mechanism responsible for the suppressive effect of decursin, we analyzed signaling molecules involved in the TLR-mediated activation of MMP-9 and cytokines. Decursin blocked phosphorylation of IkappaB and nuclear translocation of NF-kappaB in THP-1 cells activated with LPS. Furthermore, expression of a luciferase reporter gene under the promoter containing NF-kappaB binding sites was blocked by decursin. These data indicate that decursin is a novel inhibitor of NF-kappaB activation in signaling induced by TLR ligands and cytokines.</P>