환자만족도 조사설문지의 설문문항 배열에 따른 신뢰도 분석

최귀선,조우현,홍재석,이선희,강명근 한국의료QA학회 2000 한국의료질향상학회지 Vol.7 No.2

Objectives : The purpose of this study was to evaluate the reliability of questionnaire according to item arrangement on patient satisfaction questionnaire. Methods : We developed the two types of questionnaire with different item arrangement. In the first type (A), questions were arranged according to medical service dimensions. Questions in the second type (B) were arranged according to medical process. Both questionnaires were composed of six dimensions: physical environments, process, competence, courtesy, information giving, understanding patients. Measurements were performed on a 5-score Likert scale. In an outpatients and inpatient survey, total 777 patients answered the type A (outpatients: 257, inpatients: 128) or Type B (outpatients: 257, inpatients: 135). In order to compare the internal consistency of two types. Cronbach's α were calculated. Multiple regression analysis was also performed to know which type of questionnaire explain more of the overall satisfaction. Results : In outpatient survey, type A questionnaire showed higher internal consistency than B except physical environments dimension. Also in inpatient survey, type A had higer internal consistency than B in four dimensions(process, competence, courtesy, understanding patients). In the results of multiple regression analysis, type A questionnaire (R² =0.53) explained more of the variation in overall satisfaction then B questionnaire (R2=0.43) in outpatient survey. In inpatient survey, type B questionnaire (R²=0.40) explained, more of the variation in overall satisfaction than type A questionnaire (R² =0.33).But the.difference of R was not significant in inpatient survey. Conclusion : The results of this study support that type A questionnaire has higer reliability in assessment of consumer satisfaction than type B.

소아 급성 신우신염환아의 색도플러 초음파 검사의 유용성

김은미,권귀향,이혜경,홍현숙,최득린 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.1

Purpose: Urinary tract infections are common in childhood and are most frequent in those under 1 year of age. In these children, however, differentiation of the pyelonephritis from cystitis is clinically difficult. We investigated the utility of color doppler image ultrasound in the diagnosis of acute pyelonephritis(APN) in children. Results were compared with renal cortical scintigraphy using 99mTC-DMSA. Materials and Methods : 99mTc-DMSA SPECT and color doppler ultrasound were performed within 1 week intervals in 14 patients with clinically suspected APN. (aged 4months to 15years: mean 6.1 year, 7 girls and 7boys). Urine culture was considered positive if greater than 100.000 colonied of a single organism were isolated. CDI was performed with 3.5NHz convex linear probe Ultramark 9(ATL., Bothell, Washington, USA) following a standard gray scale sonogram of the kidneys. Renal cortical scintigraphy was performed with 99mTc DMSA SPeCT(PRISM 2000, Picker, USA), Axial, coronal, both sagittal pinhole images were obtained 1.5-2 hour after 1mCi isotope was injected. Renal scan was considered to be abnormal and indicative of APN when there was a focal, wedged shaped defect in radionuclide accumulation extending from the periphery of the kidney to centrally or if there was diffuse abnormality in renal tubular function. Renal scarring was defined when defects were shallow lesions along the periphery of the kidney with evidence of volume loss, or if they could be shown from prior examination to pre-date of the acute episode. The color doppler image were interpreted to be consistent with APN if there was decrease flows in the renal cortex. Results: Of the 28 kidneys were examined, renal scan showed 5 cases of abnomal findings, 3 cases were APN, 2 cases were chronic scarring. Two fo the three cases of APN showed decreased blood flow on CDI and positive culture, for a sensitivy 67%. Two cases of renal scarring due to grade V bilateral vesicoureteral reflux show decreased blood flow at right upper pole kidney on CDI, however DMSA scan had diffculties finding the new lesion due to underlying irregularity of scarred kidney. Color doppler US correctly identified 4 of 5 renal poles with APN and 21 of 23with no APN including 2 patients with false positive. The DMSA scan was used as the standard of comparison the study; the CDI has a sensitivity 67%, specificity 84%, positive predictive value 33%, negative predictive value 95%. 84% The lesion showed decreased blood flow and on one follow up case increased blood flow. The presence of prior renal scarring made interpretation of asymmetric vascularity difficult on DMSA, the use of CDI may increase the diabnostic sensitivity of sonography in pediatric pyelonephritis.

장기투석을 받은 만성 신부전 환자에서 발생한 종양에 관한 고찰

황정화,이혜경,홍현숙,박재성,김대호,권귀향,최득린,황승덕,이희발 순천향의학연구소 1996 Journal of Soonchunhyang Medical Science Vol.2 No.2

The authors tried to evaluate tumor occurrence in long-term dialysis patients with chronic renal failure. Among 359 patients, 20 patients (about 5.6%) were diagnosed with malignancy during long-term dialysis from the period of 1983 to 1995 at our nephrology department. The ultrasonographic and computed tomographic findings including the clinical features of 20 patients that were retrospectively reviewed. The mean age of the patients was 53 (37-75)years old and the ratio of male to female was 9:1. Among the 20 cases, 7 cases of hepatoma (35%) were developed. Among them, urinary tract tumors such as renal and bladder cancer were developed in 4 (20%) and 2 (10%) of the cases. Other malignant tumors were lymphoma, stomach cancer, uterine cervical cancer, cholangiocarcinoma, lung cancer, meningioma, and acoustic neuroma one case of each (each of 5.3%). The most common tumor in patients with chronic renal failure, who were receiving long-term dialysis, was hepatoma and the second most common tumor was cancer of the urinary tract such as kidney and bladder.

간내 담관암의 초음파 및 전산화 단층촬영소견 : Ultrasound and CT Findings

김완진,김표년,김일영,홍현숙,이혜경,권귀향,김기정 순천향대학교 1995 Journal of Soonchunhyang Medical Science Vol.1 No.1

신동맥 협착 정도에 따른 도플러 초음파 소견

박재성,이혜경,김대호,최득린,권귀향,홍현숙,임한혁,김기정 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.2

Renal artery stenosis is the one of causes of hypertension in a small percentage of all patients but is only anatomical cause that can be treated by means of surgery and percutanecous transluminal angioplasty. Angiography is the golden standard for diagnosis of renal artery stenosis, but a little invasive. With the advent of abdominal Doppler ultrasonography, renal artery stenosis could be diagnoed noninvasively. The experienced hands appears to be valuable in the doppler examination, ut some investigators consider it almost useless. The authors studied the effect of stenosis of renal artery on the downstream intrarenal blood flow, a snare was placed around renal artery in 12 rabbits and compressed to create stenosis while Doppler ultraonographic curve and flow index were obtained from main renal and interlobar arteries by means of placement of 10-MHz curved linear tranducer directly on the surface of kidney. The Doppler measurements were compared with the percentage of stenosis on angiograms. The results were as follow: 1. Ten satisfactory angiograms and Doppler ultrasonograms were obtained. 2. Three renal arteries were created stenosis below 70% (Group A), Seven were above 70% (Group B). 3. The ranges of RI (resistance index) were 0.61-0.86 (mean 0.78±0.154) at main renal arteries, 0.57-0.85 (mean 0.77±0.231) at interlobar artery. The range of PS (peak systolic velocity) were 13.1-28.8 (mean 21.65±4.445) m/sex at main renal artery, 5.2-18.1 (mean 11.74±4.095) m/sec at interlobar arteries. The RI of rabbits were higher than those of human (mean 0.58±0.05). 4. The range of RI in stenotic arteries of group B were 0.45-0.74 (mean 0.57±0.143) at main renal artery, 0.52-0.65 (mean 59±0.051) at interlobar arteries. The range of PS were 11.2-21.3 (mean 15.04±3.755) m/sec at main renal arte교, 5.7-11.3 (mean 8.24±2.056) at interlobar artery. The difference were statistical y significant (P=0.0302), but without remarkable change in group A. 5. Doppler ultrasonographic curve during progressive compression of renal artery showed dampened systolic waveform and diagonal upstroke at main renal arteries (71.4%) and interlobar arteries (85.7%) in group B, but without remarkable change in group A. 6. Release of the arterial compression caused higher than normal peak systolic velocity initially, at main renal arteries (42.9%) and interlobar arteries (28.6%). but the curve of all rabbits returned to normal within 5 minutes. The Doppler ultrasonographic index and curve were not changed on follow up Doppler ultrasonogram at 5 min. 10 min. 30 min. and 1 hour. The change of the systolic curves that compressed experimentally is identical to change in the pulsus tardus and parvus waveforms seen in both acute and chronic severe renal artery stenosis in humans, can helpul for the diagnosis of renal artery stenosis and the effects of treatment by percutaneous tranluminal angioplasty and surgery.

STANAG-4586의 Autonomy 구현방안 연구

박귀홍(Kui-Hong Park),조영우(Youngwo Jo),김상환(Sang-Hwan Kim) 한국항공우주학회 2022 한국항공우주학회 학술발표회 논문집 Vol.2022 No.4

로봇 영상통화 구현에 관한 연구

박귀홍(Kui-Hong Park),김종철(Jong-Cheol Kim),김현호(Hyun-Ho Kim),정성택(Sung-Taek Jung),구명완(Myoung-Wan Koo) 한국통신학회 2009 한국통신학회 학술대회논문집 Vol.2009 No.6

Aging skin in atopic dermatitis - are advanced glycation end products guilty?

( Jun Ki Hong ),( Ji Yeon Hong ),( Min Jeong Kim ),( Su Jung Park ),( Kui Young Park ),( Seong Jun Seo ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.2

Background: Advanced glycation end products (AGEs), the well-known aging biomarker, interact with the membrane-bound receptor for AGEs (RAGE), consequently amplifying inflammatory response. Soluble receptor for AGE (sRAGE) and endogenous secretory RAGE (esRAGE) act as decoy for AGE and competitively sequester RAGE ligands, thereby serving a cytoprotective role. However, there are few studies that discuss their actions in dermatologic fields, especially with atopic dermatitis (AD). Objectives: This study aimed to investigate the expression of AGE and the receptors in serum and skin of AD patients. Methods: Blood samples and corneocytes were taken from 29 adult AD patients and 12 healthy controls. The levels of AGE, sRAGE and esRAGE were evaluated by enzyme-linked immunosorbent assay. Results: Level of cutaneous AGE was elevated in AD group (p=0.002). Severe AD group showed higher skin AGE than milder group. No significant difference was found between AD patients and healthy controls in serum AGE level. Serum sRAGE was markedly decreased in AD patients (p=0.007) and serum esRAGE followed similar trend. Conclusion: Dermal accumulation of AGE in AD may have a role in fueling skin inflammation. The potential effect of reduced neutralizer - serum sRAGE - on metabolic and cardiovascular risk need further evaluation.

Adiponectin ameliorate cellular premature senescence and restitute abnormal increase of antimicrobial peptide level in senescent keratinocyte

( Ji Yeon Hong ),( Joon Seok ),( Tae Won Jin ),( Kui Young Park ),( Seong Joon Seo ),( Chang Kwun Hong ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.2

Background: Adiponectin had been nominated as a positive factor on functional recovery for its virtue against energy metabolism related regulation especially with AMP-activated protein kinase (AMPK) and SIRT1. But there are few reports related with skin or keratinocytes. Objectives: We aim to recover the possibility of adiponectin as a promising anti-aging agent and supplement for antimicrobial barrier. Methods: Adiponectin had been treated to normal or premature senescent keratinocytes. SA モ-galactosidase stain and assay, AMPK-SIRT1-FoxOs and MAPK/NFリB signal transduction pathway were evaluated by immunoblot, SIRT1 activity assay and RT-PCR. Results: The adiponectin stimulation reduced premature senescence and restituted human モ-defensin 2 and LL-37 in aged skin. Adiponectin upregulated and recovered AMPK activity in senescent keratinocyte and up-regulated SIRT1 activity suppressed NFリB p65. Conclusion: These evidences suggest the positive possibilities of anti-aging agent and improved skin immune barrier through adiponectin stimulation related signal transduction.

Gold photothermal therapy for refractory papulopustular rosacea

( Jun Ki Hong ),( Hye Sung Han ),( Hae Woong Lee ),( Kui Young Park ),( Beom Joon Kim ),( Chang Kwun Hong ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.72 No.2