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Dermatological Manifestations of Postural Tachycardia Syndrome Are Common and Diverse
Hao Huang,Anindita Deb,Collin Culbertson,Karen Morgenshtern,Anna DePold Hohler 대한신경과학회 2016 Journal of Clinical Neurology Vol.12 No.1
Background and Purpose Postural tachycardia syndrome (POTS) is a syndrome of orthostatic intolerance in the setting of excessive tachycardia with orthostatic challenge, and these symptoms are relieved when recumbent. Apart from symptoms of orthostatic intolerance, there are many other comorbid conditions such as chronic headache, fbromyalgia, gastrointestinal disorders, and sleep disturbances. Dermatological manifestations of POTS are also common and range widely from livedo reticularis to Raynaud’s phenomenon. Methods Questionnaires were distributed to 26 patients with POTS who presented to the neurology clinic. They were asked to report on various characteristics of dermatological symptoms, with their answers recorded on a Likert rating scale. Symptoms were considered positive if patients answered with “strongly agree” or “agree”, and negative if they answered with “neutral”, “strongly disagree”, or “disagree”. Results Te most commonly reported symptom was rash (77%). Raynaud’s phenomenon was reported by over half of the patients, and about a quarter of patients reported livedo reticularis. Te rash was most commonly found on the arms, legs, and trunk. Some patients reported that the rash could spread, and was likely to be pruritic or painful. Very few reported worsening of symptoms on standing. Conclusions Te results suggest that dermatological manifestations in POTS vary but are highly prevalent, and are therefore of important diagnostic and therapeutic signifcance for physicians and patients alike to gain a better understanding thereof. Further research exploring the underlying pathophysiology, incidence, and treatment strategies is necessary.
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