http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Imtiyaz Ahmad Bhat,Bibhisan Roy,Kabir-ud-Din 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.63 No.-
Compilation of novel surfactant–protein mixtures has always been an intriguing and fascinating domain owing to their implications in industrial and cosmetic realms. In this regard, herein; we have synthesized a new cleavable gemini surfactant and investigated its influence on the structural characteristics of lysozyme via state-of-art techniques. Results have demonstrated the complex formation, unfolding and stabilization of lysozyme upon gemini surfactant combination. Docking/DFT has shown that gemini binds in the vicinity of hydrophobic residues (Trp/Tyr) and interacts via both electrostatic and hydrophobic contributions. This study may be significant to devise novel surfactant–protein mixtures for their end use at industrial stratum.
Imtiyaz Ahmad Bhat,Bibhisan Roy,Kabir-ud-Din 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.77 No.-
In this communication we have observed that cleavable gemini surfactant micelles inducefluorescenceswitching in novel probe (bound to lysozyme) at lower concentrations ( 2.63 mM) compared toconventional surfactants, which are known to induce such phenomenon at above 30 mM. Fluorescenceswitching being important in sensing, binding, and probing the conformational states of proteins;therefore, in future this study could be significant to protein analytics and other relevant industrialdomains.
Malik Abdul Rub,Abdullah M. Asiri,Naved Azum,Kabir-ud-Din 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.4
The purpose of the present study was to determine the influence of various anionic hydrotropes on the self-aggregation and phase behavior of amphiphilic drug promazine hydrochloride (PMZ) and to search for means which reduce/increase the values of critical micelle concentration (cmc) and boost/suppress the cloud point (CP), respectively, used in pharmaceutical formulations. By using regular solution theory (RST) and Rosen’s model various micellar and surface properties such as micellar composition, surface excess concentration (Gmax), interaction parameters (bm, bs) etc. have been determined. The solution micellar behaviors were also investigated using Motomura and Rodenas models for defense and comparison of results. Thermodynamic parameters were also evaluated and discussed.
A.J. Khanam,M.S. Sheikh,I.A. Khan,Kabir-ud-Din 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.5
The purpose of the present study was to determine the influence of various additives on the aggregation behavior of gemini surfactants and to search for means which reduce the values of critical micelle concentration. The mixed micellar properties of cationic hydrotropes (aniline hydrochloride, paratoluidine hydrochloride, ortho-toluidine hydrochloride), anionic hydrotropes (sodium salicylate, sodium benzoate, sodium tosylate) and nonionic hydrotropes (phenol, resorcinol, pyrogallol) with conventional alkyl tetradecylammonium bromide (TTAB) and their dimeric homologues viz., 14-s-14, (s = 4, 5, 6) in aqueous medium have been studied using conductometric technique at four different temperatures ranging from 298.15 K to 313.15 K. The evaluated thermodynamic parameters have been discussed in detail.
Jeenat Aslam,Umme Salma Siddiqui,Imtiyaz Ahmad Bhat,Kabir-ud-Din 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.5
In the present study, mixtures of cationic gemini surfactants with a non-ionic sugar-based surfactant in aqueous solutions containing electrolyte (NaBr) have been studied. The experimental results were evaluated using the Regular Solution Theory. The strength of interaction of all the surfactants is attributed to the sterical and electrical factors on mixed monolayer and micelle formation and of surfactant–surfactant interactions. The results show stronger interaction at the air/water interface and greater preference for adsorbing at the air/water interface relative to mixed micelle formation in the solution phase. The alkyl chain length and spacer of gemini govern the aggregation behavior of the mixed micelles.
Mohd. Akram,Imtiyaz Ahmad Bhat,Abiyu Kerebo Berekute,Kabir-ud-Din 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.40 No.-
Herein, we have investigated the effect of inorganic and organic salts (NaCl, Na2SO4, Na3PO4, NaAn andNaTos) on the solution behaviour of a gemini surfactant, ethane-1,2-diyl bis(N,N-dimethyl-N-dodecylam-moniumacetoxy) dichloride (12-E2-12), employing surface tensiometry, fluorescence, 1H NMR, TEM, UV–vis, and FT-IR. The surface tension measurements showed that all micellization characteristics were refinedin the presence of salts with the order being NaAn > NaTos > Na3PO4 > Na2SO4 > NaCl. Whereasfluorescence measurements were used to estimate the aggregation number (Nagg) of the micelles. 1HNMR, TEM, UV–vis, and FT-IR results revealed morphological transition and newer phase formation. Thisstudy in future could be useful for compilation of surfactant–salt mixtures for industrial applications.
Malik Abdul Rub,Abdullah M. Asiri,Naved Azum,Anish Khan,Aftab Aslam Parwaz Khan,Sher Bahadar Khan,Mohammed M. Rahman,Kabir-ud-Din 한국공업화학회 2013 Journal of Industrial and Engineering Chemistry Vol.19 No.6
Herein we report the micellization and cloud point of an amitriptyline hydrochloride (AMT) under the influence of cationic, anionic and nonionic hydrotropes. Anionic hydrotropes were employed to know the micellar and surface behaviors, besides studying the clouding behavior of AMT drug with cationic,anionic and nonionic hydrotropes. Tensiometric study has been performed and the properties studied include the critical micelle concentration (cmc), maximum surface excess at the air/water interface (Gmax), the minimum area per of amphiphilic molecule at air/water interface (Amin), and the different thermodynamic parameters, besides clouding phenomenon. Interaction parameters of micelles (bm) and monolayer (bs) indicate that drug-hydrotrope systems show better interaction at the interface than in micelles.