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Park, Jungmin,Ku, Minhee,Kim, Eunjung,Park, Yeonji,Hong, Yoochan,Haam, Seungjoo,Cheong, Jae-Ho,Park, Eun Sung,Suh, Jin-Suck,Huh, Yong-Min,Yang, Jaemoon Oxford University Press 2013 Integrative biology Vol.5 No.4
<P>We describe a near-infrared-sensitive molecular imaging probe based on hydrogel complexes that can target a stem-like gastric cancer cell marker (CD44, a marker that often correlates with a poor prognosis in patients). Thus, CD44-targetable and near-infrared-sensitive supramolecular hydrogels (NIRSHs, Cy5.5-conjugated polyethyleneimine/hyaluronic acid polyplexes) were fabricated by polyplexing in an aqueous medium. NIRSHs demonstrated good water-stability, biocompatibility, and specificity to CD44-expressing stem-like gastric cancer cells. Furthermore, NIR-sensitive in vivo imaging potentials of CD44-targetable NIRSHs for heterotopic/orthotopic xenograft mouse models were investigated.</P>
Shape Optimization of Flow Channels Using Lattice Boltzmann Method
Jungmin Park(박정민),Kyung Chun Kim(김경천) 대한기계학회 2016 대한기계학회 춘추학술대회 Vol.2016 No.12
A new optimality criterion algorithm is presented for producing modified shape designs for fluid flow inside channels. To compute the fluid motion in a channel, the Lattice Boltzmann Method (LBM) was used based on D2Q9 lattice spaces associated with the Bhatnagar-Gross-Krook (BGK) collision term. An experiential optimality method to design channels with the lowest pressure drop along the passage is introduced. The positions of solid cells and fluid cells are exchanged based on the strain rate tensor at the solid-fluid interface. To obtain the optimized shape, the cells are changed until the optimality condition is obtained with the restriction of constant fluid volume. Examples are presented to validate the algorithm, including an elbow tube as well as symmetrical and nonsymmetrical T-junction channels. The validation exercises demonstrate that the algorithm is suitable for optimal channel design.
THE EFFECTS OF E-MASS CUSTOMIZATION OF LUXURY BRAND: PERCEIVED VALUE, SATISFACTION, AND LOYALTY
Jungmin Yoo,Minjung Park 글로벌지식마케팅경영학회 2015 Global Fashion Management Conference Vol.2015 No.06
Mass customization refers to a strategy whereby online retailers provide individually tailored products and services to their customers and has been implemented by many retailers with the Internet technology. Many luxury brands such as Bottega Venetta, Louis Vuitton, and Salvatore Ferragamo, provide customization programs to better serve their customers, from engraving their initials on a product to creating a new design of a product. However, the expansion of the customization program to the luxury brands raises potential risk, such as loosening the brand identity and inability to satisfy customers. Despite high interests in mass customization programs and popularity of luxury brands, the effect of mass customization in luxury brands has not been explored. Addressing this gap in the literature, this study attempts to investigate how customized products of luxury brands influence perceived value, satisfaction, and loyalty. In addition, this study explores how consumers’ past loyalty toward a luxury brand influences perceived value of the customization. Hypotheses of the study were (1) Perceived value of a mass-customized product has a positive influence on satisfaction with product customization; (2) Satisfaction with product customization has a positive influence on brand loyalty; (3) The influences of perceived value of a mass-customized product on satisfaction and brand loyalty are different as a function of a customer’s past loyalty; (4) The influences of perceived value of a mass-customized product on satisfaction and brand loyalty are different as a function of a customer’s need for uniqueness. The research strategy of this study was survey methodology and the sample of the study was online shopping consumers. Online questionnaires were collected by an online survey firm. After visiting ‘BURBERRY BESPOKE’, a mass-customization program of a luxury brand, survey participants were asked to answer the questionnaire. The instrument tapped perceived value of a mass-customized product, satisfaction with product customization, past/future brand loyalty, and need for uniqueness. A total of 304 female online shoppers participated in the survey. The result of structural equation modeling found the positive effects of hedonic value and utilitarian value on satisfaction with product customization and the positive effect of the satisfaction on brand loyalty. The result of multiple group comparison analyses revealed the moderating roles of past loyalty and need for uniqueness in influencing the effects of perceived value of a mass-customized product on satisfaction. These findings of the study contribute to the literature in luxury brand retailing fields and suggested managerial implications to luxury brand retailers.