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정용진,서권일,이기동,윤광섭,강미정,김광수 동아시아식생활학회 1998 동아시아식생활학회지 Vol.8 No.1
To utilize deteriorated sweet persimmon effectively, response surface methodology(RSM) was used to determine the optimal vinegar fermentation conditions and monitored by a divided two stage fermentation. The optimum conditions for maximum alcohol content were obtained when the first stage (alcohol fermentation) was carried out with an initial sugar concentration of 18.5°Brix, agitation rate of 140.8 rpm, fermentation time of 127.6 hr. When sugar concentration was 14°Brix, maximum alcohol content(7.1%) was predicted at fermentation conditions of 160 rpm in agitation rate, 140 hr in fermentation time. The optimum conditions for maximum acidity were obtained when second stage(vinegar fermentation) was carried out 249.5 rpm in agitation rate, 148.8 hr in fermentation time. Predicted values at the optimum conditions were similar to experimental values.
Clinoptilolite 계열의 국내산 천연제올라이트의 상규명 및 NH₄^+ : 이온교환능에 관한 연구
김화중,이기정,이명철 건국대학교 1995 學術誌 Vol.39 No.2
Domestic natural zeolite, Clinoptilolite series was investigated to identify the phase and to study the capability of NH4+-ion removal from the solution system. The domestic natural zeolite mined from Young-II man area was proven to be a thermally unstable zeolite, heulandite by XRD and FT-IR analyses. In addition, the heulandite exchanged by K+ ion showed the highest thermal stability upon the heat-treatments. However, the best capability of removing NH4+-ion from the solution system was the Na+-exchanged zeolite.
Regulation of Stem Cell Fate by ROS-mediated Alteration of Metabolism
Ryu, Jung Min,Lee, Hyun Jik,Jung, Young Hyun,Lee, Ki Hoon,Kim, Dah Ihm,Kim, Jeong Yeon,Ko, So Hee,Choi, Gee Euhn,Chai, Ing Ing,Song, Eun Ju,Oh, Ji Young,Lee, Sei-Jung,Han, Ho Jae Korean Society for Stem Cell Research 2015 International journal of stem cells Vol.8 No.1
<P>Stem cells have attracted much attention due to their distinct features that support infinite self-renewal and differentiation into the cellular derivatives of three lineages. Recent studies have suggested that many stem cells both embryonic and adult stem cells reside in a specialized niche defined by hypoxic condition. In this respect, distinguishing functional differences arising from the oxygen concentration is important in understanding the nature of stem cells and in controlling stem cell fate for therapeutic purposes. ROS act as cellular signaling molecules involved in the propagation of signaling and the translation of environmental cues into cellular responses to maintain cellular homeostasis, which is mediated by the coordination of various cellular processes, and to adapt cellular activity to available bioenergetic sources. Thus, in this review, we describe the physiological role of ROS in stem cell fate and its effect on the metabolic regulation of stem cells.</P>
Jung, Kyu-Seok,Heu, Sung-Gi,Roh, Eun-Jung,Kim, Min-Ha,Gil, Hyun-Ji,Choi, Na-Young,Lee, Dong-Hwan,Lim, Jeong-A,Ryu, Jae-Gee,Kim, Kye-Hoon 한국토양비료학회 2013 한국토양비료학회지 Vol.46 No.6
Animal manure compost is a commonly used fertilizer in organic vegetable and fruit production in Korea. However, livestock manure compost produced from animal feces can contain a lot of the non-pathogenic and pathogenic bacteria. Of particular concern are bacteria causing human food-borne illness such as Escherichia coli O157:H7 and Listeria monocytogenes. The objective of this study was to investigate effect of temperature on survival of E. coli O157:H7 and L. monocytogenes in livestock manure compost. Commercial livestock manure compost (manure 60%, sawdust 40%) was inoculated with E. coli O157:H7 and L. monocytogenes. Compost was incubated at four different temperatures (10, 25, 35, and $55^{\circ}C$) for 20 weeks. Samples were taken every week during incubation depending on the given conditions. E. coli O157:H7 persisted for up to 1 day in livestock manure compost at $55^{\circ}C$, over 140 days at $10^{\circ}C$, 140 days at $25^{\circ}C$, and 120 days at $35^{\circ}C$, respectively. L. monocytogenes persisted for up to 1 day in livestock manure compost at $55^{\circ}C$ and 140 days at $10^{\circ}C$, 70 days at $25^{\circ}C$, and 40 days at $35^{\circ}C$, respectively. The results indicated that E. coli O157:H7 and L. monocytogenes persisted longer under low temperature condition. E. coli O157:H7 survived longer than L. monocytogenes at three different temperatures (10, 25, and $35^{\circ}C$). The results are being used to develop guidelines on the management of manure to reduce the risks of E. coli O157:H7 and L. monocytogenes transmission to foods produced in the presence of animal waste.
Jung, Kyu-Seok,Kim, Min-Ha,Heu, Sung-Gi,Roh, Eun-Jung,Lee, Dong-Hwan,Lim, Jeong-A,Ryu, Jae-Gee,Kim, Kye-Hoon 한국토양비료학회 2014 한국토양비료학회지 Vol.47 No.6
While searching for healthier diets, people became more attentive to agricultural organic products. However, organic foods may be more susceptible to microbiological contamination because of the use of livestock manure compost and liquid manure, potential sources of pathogenic bacteria. This study was undertaken to investigate the persistence of Salmonella enterica, Escherichia coli O157:H7, and Listeria monocytogenes in soil, liquid manure amended soil, and liquid manure. Loamy soil, liquid manure amended soil, and liquid manure were inoculated with S. enterica, E. coli O157:H7, and L. monocytogenes. Samples were incubated in consistent moisture content at $25^{\circ}C$. Samples had been periodically collected during 120 days depending on the given conditions. S. enterica and E. coli O157:H7 survived over 120 days in loamy soil and over 60 days in liquid manure amended soil, respectively. L. monocytogenes decreased faster than other pathogens in soil. S. enterica, E. coli O157:H7, and L. monocytogenes survived for up to 5 days in liquid manure. S. enterica and E. coli O157:H7 in soil decreased by 2 to $2.5log\;CFU\;g^{-1}$ for 120 days. S. enterica and E. coli O157:H7 in liquid manure amended soil decreased slowly for 21 days. However, S. enterica, E. coli O157:H7, and L. monocytogenes sharply decreased after 21 days. S. enterica, E. coli O157:H7, and L. monocytogenes in soil increased by 0.5 to $1.0log\;CFU\;g^{-1}$ for 7 days. Foodborne pathogens in soil and liquid manure amended soil gradually decreased over time.
Survival of Salmonella enterica and Listeria monocytogenes in Chicken and Pig Manure Compost
Jung, Kyu-Seok,Heu, Sung-Gi,Roh, Eun-Jung,Kim, Min-Ha,Gil, Hyun-Ji,Choi, Na-Young,Lee, Dong-Hwan,Lim, Jeong-A,Ryu, Jae-Gee,Kim, Kye-Hoon 한국토양비료학회 2013 한국토양비료학회지 Vol.46 No.6
Livestock manure is a valuable source of nutrients and organic matter for plant. Thus, livestock manure compost is commonly used fertilizer in organic vegetable and fruit production in many countries. However, contaminated or inadequate manure compost can give negative effect to soil microorganisms. This study was conducted to investigate the survival difference of Salmonella enterica and Listeria monocytogenes in chicken and pig manure compost under the selected environmental conditions. Commercially available manure compost (pig, chicken) was inoculated with S. enterica and L. monocytogenes. Manure compost was incubated at $25^{\circ}C$ and consistent moisture content. Samples had been collected during 200 days depending on the given conditions. S. enterica survived for 130 days in pig manure compost and over 200 days in chicken manure compost, respectively. L. monocytogenes persisted for 120 days in pig manure compost and over 200 days in chicken manure compost, respectively. It is noted that the number of S. enterica and L. monocytogenes gradually decreased over time. The results indicate that S. enterica survived longer than L. monocytogenes in manure compost at $25^{\circ}C$. S. enterica and L. monocytogenes survived longer in chicken manure compost than in pig manure compost. Increased knowledge of pathogen behavior in agricultural environments is a valuable part of future work on improving risk evaluations and, in a longer perspective, in providing data for guidelines regarding safe handling of pathogen-contaminated manure compost and soil.
Yeom Gee Bok,Lee Hyung Cheol,Ju Sung Min,Kim Kun Jung,Kim Won Sin,Lee Chae Ho,Jang Ho Yeon,Kang Jeong Ho,Park Shin Ki,Lee Key Sang,Jeon Byung Hun The Physiological Society of Korean Medicine and T 2003 동의생리병리학회지 Vol.17 No.6
To investigate the antioxidant capacity of traditional Korean medicines, water extracts from 57 species were tested on their antioxidant activity using radical scavenging effects against ABTSㆍ+. Of which, Rhus javanica, Caesalpinia sappan, Rosa rugosa, Spatholobus suberectus, and Magnolia obovata showed strong antioxidant capacities at 10㎍ concentration. Therefore, antioxidant capacities of 5 traditional medicine extracts in the different concentration (1㎍, 5㎍, and 10㎍) were determined. The 5 traditional medicine extracts was detected in antioxidant capacity dose dependently. R. javanica was showed the highest antioxidant capacity, the antioxidant activity at 1 ㎍ of herbal extract being 0.85 mM TE. At the same time, the antiperoxidation effects of these 5 medicines were determined. Lipid peroxidation in brain homogenates induced by NADPH and ADP-Fe/sup 2+/ was strong inhibited by S, suberectus, R. rugosa, and M. obovata. Extract of C. sappan was showed the highest inhibition against lipid peroxidation compared with 4 herbal extracts in vitro. These traditional medicines are a potent antioxidant capacity and antiperoxidation activity, further investigation into the in vivo antioxidant therapeutic potential for treatment of human disorders such as Alzheimer's disease.
폐암절제술후 발생하는 사망 및 합병증의 예측인자 평가에 관한 전향적 연구
박정웅 ( Jeong Woong Park ),서지영 ( Gee Young Suh ),김호철 ( Ho Cheol Kim ),천은미 ( Eun Mee Cheon ),정만표 ( Man Pyo Chung ),김호중 ( Ho Joong Kim ),권오정 ( O Jung Kwon ),김관민 ( Kwan Min Kim ),김진국 ( Jin Kook Kim ),심영목 ( 대한결핵 및 호흡기학회 1998 Tuberculosis and Respiratory Diseases Vol.45 No.1