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정영건,지원대,김성영,곽동주,서수교,백경연 한국위생과학회 1997 한국위생과학회지 Vol.3 No.1
The effect of oriental medicines an the growth of oral bacteria(B. pumilus JU4, B. coagulans JU6, B. subtilis var globigii JU7 and B. subtilis var. globigii JU9) which were isolated from teeth, gums and tongues of patients was investigated. lt was shown that the water extracts of Glycyrrhiza glabra L. var. glandulifera Regel et Zucc., Schizandrae Fructus and Coptidis Rhizoma have the strong antimicrobial activity against every test organism. Especially, the water extract of Schizandrae Fructus has the most antimicrobial activity against all test bacteria of which MIC were the same as 0.25%. The growth of oral bacteria B. pumilus JU4 was inhibited by addition of the water extracts of Glycyrrhizae Radix, Schizandrae Fructus and Coptidis Rhizoma in the concentration of 0.9%, 0.2% and 0.1% respectively. It was tested that specific growth rates of B. pumilus JU4 in each concentration of the water extracts of Glycyrrhizae Radix, Schizandrae Fructus and Coptidis Rhizoma. From the results, the test showed that mean of specific growth rates of B. pumilus JU4 decreased 102%, 186% and 210% in 3% concentration of the water extracts of Glycyrrhizae Radix, Schizandrae Fructus and Coptidis Rhizoma more than those in control respectively.
원발성 유방암에서 Sodium Iodide Symporter의 발현과 ^(99m)Tc-MIBI 유방스캔의 관계
석주원,김성장,곽희숙,이창훈,김인주,김용기,배영태,김동수 대한핵의학회 2002 핵의학 분자영상 Vol.36 No.6
목적: hNIS는 갑상선 조직 외에 다른 조직들에서도 발현된다고 알려져 있다. 유방암 세포는 그런 조직들 중에 하나이며, 그에 의한 유방암의 방사성옥소치료의 가능성이 제시되고 있다. 본 연구에서는 유방암 조직에서 hNIS의 발현정도를 알아보고, ^99mTc-MIBI 유방스캔과 hNIS의 발현 정도와의 관계를 조사하여 보았다. 대상 및 방법: 본 연구에서는 유방암으로 수술을 시행했던 56명의 환자를 대상으로 하였다. hNIS의 발현은 면역조직화학염색에 의해서 평가되었으며, 그 결과를 ^99mTc-MIBI 유방스캔의 판정 결과와 비교하였다. 결과: 전체 56명의 환자에서 hNIS의 발현율은 41.1%였다. 병리학적 진단에 의해 침윤성관상피암종이었던 49명에서의 발현율은 42.9%, 관상피내암종이었던 7명에서의 발현율은 28.6%였다. ^99mTc-MIBI 유방스캔에서 국소섭취 소견이 관찰되었던 41명에서의 hNIS의 발현율은 31.7%였다. 비정상적인 섭취 소견이 관찰되지 않았던 15명의 환자에서의 hNIS의 발현율이 의미있게 높게 관찰되었다(66.7%, p>0.05). 결론: 유방암 환자에서의 hNIS의 발현율은 그다지 높지 않았다. ^99mTc-MIBI 유방스캔에서 섭취증가 소견이 없을 때 hNIS의 발현율이 더 높았다. Purpose: Human Na^+/I- symporter (hNIS) is known to be expressed in many tissues other than thyroid gland. The breast cancer cells are one of them and the possibility of radioiodine therapy in treatment of the breast cancer may be suggested. We investigated the expression rate of hNIS and the relationship between the expression of hNIS and the finding of 99mTc-MIBI scintimammography in the breast cancer. Materials and Methods: Surgically proved 56 patients with breast cancer were the subjects of this study. The expression of hNIS were evaluated by immunohistochemistry and the results were compared to the findings of 99mTc-MIBI scintimammography. Results: Overall expression rate of hNIS was 41.1% in 56 patients. According to the pathologic diagnosis, it was 42.9% in 49 patients with invasive ductal carcinoma and 28.6% in the 7 patients with ductal carcinoma in situ. The expression rate of hNIS in the 41 cases with a focal increased uptake at he breast lesion on 99mTc-MIBI scintimammogram was 31.7%. That in the 15 cases without any abnormal uptake on the scan was significantly higher(66.7%, p<0.05). Conclusion: The expression rate of hNIS in the patients with breast cancer was not so high. The rate was higher in the patients with no increased uptake at the breast lesion on 99mTc-MIBI scintimammography. (Korean J Nucl Med 2002;36;325-32)
한국 대도시 고령자의 체격, 체력 및 운동실태와 운동 프로그램개발에 관한 연구
김경지,강동원,장주호,전익기,윤우상,곽은창,박영진,유재충 경희대학교 사회체육연구소 1996 體育科學論叢 Vol.- No.9
The purpose of this study was to investigate the patterns of the health related variables, and physical characteristics and physical fitness of the elderly people in order to provide a exercise program. The data about the health related variables were collected through the personal interview, and the data about physical charateristics and physical fitness (height, weight, % body fat, blood pressure, pulse rate, grip stength, trunk flexion, side step test, 2 min, harvard step test) of 373 elderly people living Seoul and kyungkee area were collected. The conclusions of this study can be summarized as follow; 1. The test results about smoking, drinking, sleeping and self-evaluation of health revealed that the elderly people have self-confidence about their health. 2. Not many elderly people participate the proper exercise program even though they recognize the need of exercise. 3. The results showed that the elderly people do not pay much attention to the intensity of the exercise. 4. Muscle strength training for leg and the lower back and cardio-vascular endurance training was recommended to reduce the risk of varius problems caused by aging. 5. A exercise program was suggested for the elderly people.
A Case of Significant Endobronchial Injury due to Recurrent Iron Pill Aspiration
Kwak, Joo-Hee,Koo, Gun Woo,Chung, Sung Jun,Park, Dong Won,Kwak, Hyun Jung,Moon, Ji-Yong,Kim, Sang-Heon,Sohn, Jang Won,Yoon, Ho Joo,Shin, Dong Ho,Park, Sung Soo,Pyo, Ju Yeon,Oh, Young-Ha,Kim, Tae-Hyung The Korean Academy of Tuberculosis and Respiratory 2015 Tuberculosis and Respiratory Diseases Vol.78 No.4
Gastric mucosal damage by iron pills is often reported. However, iron pill aspiration is uncommon. Oxidation of the impacted iron pill causes bronchial mucosal damage that progresses to chronic bronchial inflammation, necrosis, endobronchial stenosis and rarely, perforation. We reported a case of a 92-year-old woman with chronic productive cough and significant left-sided atelectasis. Bronchoscopy revealed substantial luminal narrowing with exudative inflammation of the left main bronchus. Bronchial washing cytology showed necroinflammatory exudate and a small amount of brown material. Mucosal biopsy showed diffuse brown pigments indicative of ferrous pigments, crystal deposition, and marked tissue degeneration. After vigorous coughing, she expectorated dark sediments and her symptoms and radiological abnormalities improved. There are a few such reports worldwide; however, this was the first case reported in Korea. Careful observation of aspiration-prone patients and early detection of iron pill aspiration may prevent iron pill-induced bronchial injury.
Has the dominant search engine, if any, discriminated against rival websites?
( Ju Won Kwak ) 한국산업조직학회 2015 한국산업조직학회 정책세미나 논문집 Vol.2015 No.1
Some dominant horizontal search engines have recently been facing antitrust charges worldwide, based on allegations that they give preference to their own contents and discriminate against their rivals. In this short article, we use Internet tra c data to test whether the entry of a dominant search engine to certain downstream Internet service markets has a ected the out ow of Internet tra c from this search engine to its downstream rivals. We do not nd any empirical evidence of such a search bias.
How Essential and Biased are Search Engines? Empirical Evidence from the Flow of Internet Traffic
( Ju Won Kwak ) 정보통신정책학회 2015 정보통신정책연구 Vol.22 No.4
Dominant horizontal search engines have recently been facing antitrust challenges around the globe based on allegations that their search results are biased. In this short article, we present empirical evidence based on Internet traffic data from Korea that weakly supports this search bias claim. In short, we show that search engines tend to herd their users back to their own content significantly more than their share of overall page views. Moreover, about a quarter of all page views originating from outside sources come from search engines, thus suggesting that search engines are fairly important to most websites. However, results of this study do not fully justify immediate antitrust intrusion. Instead, they may be used as an initial test for a more thorough scrutiny.
Individual having a parent with early-onset gastric cancer may need screening at younger age.
Kwak, Hee-Won,Choi, Il Ju,Kim, Chan Gyoo,Lee, Jong Yeul,Cho, Soo-Jeong,Eom, Bang Wool,Yoon, Hong Man,Joo, Jungnam,Ryu, Keun Won,Kim, Young-Woo WJG Press 2015 WORLD JOURNAL OF GASTROENTEROLOGY Vol.21 No.15
<P>To evaluate whether individuals with gastric cancer (GC) are diagnosed earlier if they have first-degree relatives with GC.</P>