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        비아그라??복용 후 발생한 급성 심근경색증

        유지영,왕순주,조성훈 대한응급의학회 2001 대한응급의학회지 Vol.12 No.2

        Erectile dysfunction(ED) is defined as the inability to achieve and/or maintain an erection which is sufficient for satisfactory sexual activity. Risk factors for ED include many of the same risk factors for cardiovascular disease: hypertension; lipid abnormalities, including low high-density lipoprotein cholesterol; diabetes; and smoking. Therefore, some patients with ED will have ischemic heart disease. Viagra□, an oral therapy for ED, is the citrate salt of sildenafil, a selective inhibitor of cyclic guanosine monophosphate(cOMP)-specific phosphodiesterase 5(PDE5). The adverse effects of sildenafil include headache, flushing, dyspepsia, nasal congestion, visual disturbance, and cardiovascular complications. A general impression exists that cardiovascular complications of sildenafil occur mainly when the drug is taken concomitantly with nitrate. We report the case of a 52-year-old man who developed an acute myocardial infarction shortly after taking one tablet of sildenafil without sexual activity. The patient had not been using nitrates. Physicians treating patients with chest pain should be aware of the potential consequences of giving nitrates to patients taking sildenafil. We suggest that before initiating therapy, the history of sildenafil ingestion be obtained from patients with suspected myocardial infarction.

      • KCI등재

        응축형 복합레진의 기계적 성질에 관한 비교연구

        정지아,문주훈,고영곤 대한치과보존학회 2001 Restorative Dentistry & Endodontics Vol.26 No.6

        The purpose of this study was to compare the mechanical properties of three condensable composite resins and one hybrid composite resin. The compressive strength, diametral tensile strength, Vicker's microhardness were tested for mechanical properties of condensable composite resins (SureFil, Ariston pHc, Synergy compact), and hybrid composite resin (Z 100). The tested materials were divided into four groups : control group - Z 100 (3M Co, USA), experimental group I- Ariston pHc, (Vivadent, Co., Liechtenstein) , experimental group II - SureFil (Dentsply, Co., U.S.A.) , experimental group III- Synergy Compact (Coltene, Co., Swiss) . According to the above classification, we made samples of SureFil, Ariston pHc, Synergy Compact, Z 100 with separable cylindrical metal mold. And then, we measured and compared the value of compressive strength, diametral tensile strength and Vicker's microhardness of each sample. The results were as follows : 1. In compressive strength, control group (Z 100) revealed the highest value (398.85±19.61MPa), and followed by SureFil (381.65±31.24MPa), Synergy compact (354.85±12.22MPa), Ariston pHc (308.60±36.88MPa). There were no significant differences between SureFil group and Z 100 group, whereas there were significant differences between SureFil group and Ariston pHc group (P<0.05) . 2. In diametral tensile strength, Synergy compact revealed the highest value (86.54±3.44MPa) and followed by SureFil (84.54±3.53MPa), Z100 (76.91±1.63MPa), Ariston pHc(60.34±6.95MPa). There were no significant differences between SureFil group and Synergy compact group 3. In microhardness, control group (Z 100)revealed the highest value (223.7 ±58.0Hv), and followed by SureFil (117.5±10.2Hv), Ariston pHc (116.2±11.9Hv), Synergy Compact (101.9±10.8Hv). There were no significant differences between Ariston pHc group and Synergy compact group Key words : Condensable composite resin, Compressive strength Diametral tensile strength, Vicker's microhardness

      • 남자 대학생에서 걷기와 달리기 운동 시 체지방과 골격근량에 대한 비교

        김아름,강지선,노홍서,오지훈,강현주 순천향대학교 기초과학연구소 2021 순천향자연과학연구 논문집 Vol.27 No.1.2

        The purpose of this study was to investigate the difference in body fat mass and skeletal muscle mass during walking and running after resistance training based on healthy college student. One male college student (age = 25 years, Height = 175.0 cm, Weight = 86.9 kg, Body fat = 27%) volunteered to participate in the study. Body composition was assessed by bioelectrical impedance (Inbody 270, Korea). Walking exercise (4.8 km/hr, 60 min) was performed for 3 weeks, followed by running exercise (7.0 km/hr, 26 min) for 3 weeks. The experimental results are as follows. Running was more effective at dropping body weight and BMI than walking, however walking was more effective at reducing body fat (%) and increasing skeletal muscle mass (kg) than running in male college student. In conclusion, both walking and running provide benefits for body composition, and the best exercise for weight and body fat loss is the one that it actually do on a regular basis.

      • AZO 투명전도막의 전기 광학적 특성에 미치는 PET 기판 표면처리 효과

        박병욱,김지훈,성열문,추영배,곽동주 경성대학교 공학기술연구소 2008 공학기술연구지 Vol.15 No.-

        In this paper aluminium-doped zinc oxide(ZnO:Al) conducting layer was deposited on polyethylene terephthalate(PET) substrate by r. f. magnetron sputtering method PET substrate was modified by a DBD(dielectric barrier discharge) plasma before sputtering to improve the electric and optical properties of ZnO:Al film and to increase also the deposition rate The effect of heat treatment time on the dectrical, optical, chemical and structural properties of ZnO:Al thin film were investigated experimentally The PET films modified with the DBD plasma showed a significant decrease in water contact angle The deposition rate of ZnO:Al film in the case of the plasma-treated substrate was also increased by around 2 times compared to the untreated substrate The minimum resistivity of about 28×10-3 Ω-cm and transmittance of about 83.3% were obtained under the experimental condition of 6min of heat treatment time.

      • 수술로 호전되지 않은 췌장 농양을 내시경 치료로 완치한 1 예

        서희영;전태주;김선영;강미선;허란;박지영;서동대;오태훈 인제대학교 백병원 2011 仁濟醫學 Vol.32 No.-

        Necrotizing pancreatitis develops in about 10-20% of patients with acute pancreatitis, and pancreatic abscesses develop in 3% of them. The mortality of pancreatic abscess has been reported up to 40% in one study. Recently, there are several reports that show good results with n on-surgical therapy, such as percutaneous drainage and endoscopic drainage, but if the non-surgical drainage fails, surgical therapy are recommended. However, there is no definite therapeutic method which is suggested yet so far after the failure of the surgical drainage. So we report the case in which we experienced successful treatment of pancreatic abscess by endoscopic removal of necrotic tissue through the gastrocystostomy, after the failure of the surgical debridement and internal drainage through gastrocystostomy.

      • ZnO:AI 과 ITO 투명전도막을 이용한 플랙시블 DSCs의 변환효율 특성

        정기영,김지훈,성열문,곽동주,추영배 경성대학교 공학기술연구소 2010 공학기술연구지 Vol.16 No.-

        In order to investigate the possible application of ZnO films as a transparent conducting oxide (TCO) electrode for film-typed dye sensitized solar cell(F-DSC), ZnO:Al films were prepared by RF magnetron sputtering method. The effects of gas pressure on the structural and electrical properties of ZnO films were mainly studied experimentally. F-DSC using either a ZnO:Al or indium tin oxide (ITO) electrode were also fabricated separately under the same manufacturing conditions. The electro-optical conversion efficiency and fill factor of the F-DSCs using both ZnO:Al and ITO transparent conducting electrodes were measured and compared with each other. ZnO:Al films showed the minimum resistivity of 2.6 x10^(-3)Ω-cm and a transmittance of 91.7% under the experimental conditions of doping concentration of 2 wt% of Al₂0₃ and gas pressure of 5mTorr. ITO films fabricated at 5mTorr of gas pressure also showed the minimum resistivity of 1.5x10^(-3)Ω-cm and transmittance of 92.1%. Although the electrical resistivity of ZnO:Al is higher than that of ITO, the conversion efficiency of F-DSC using ZnO:Al was comparable with that of F-DSC using ITO. The conversion efficiency of F-DSCs using ZnO:Al and ITO electrodes are about 2.8% and 2.9%, respectively.

      • 허혈성 심질환에서 나타나는 항산화지수, 사이토카인 및 염증지표의 변화

        전상훔,안지훈,방덕원,온영근,현민수,김성구,권영주 순천향대학교 교수학습개발센터 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

        Purpose : As diet habits change and the elderly popuation increases conronary artery disease(CAD) has also increased. Recent ongoing studies on varous inflammatory indexes in acute coronary syndrome(ACS) are underway. Several study results have shown that total antioxidant status(TAS) was remarkably lower in unstable angina than in chronic stable angina and levels of interleukin-(IL-6), C-reactive protein(CRP), monocyte chemoattractant protein-1(MCP-1), P-selectin were reported to be elevated in unstable angina and acute myocardial infarction(AMI). In our study, we studied and compared the level changes of cytokines and inflammatory indexes that play important roles inside the blood vessel. Methods : Study subjects were patients who were admitted and underwent coronary angiography at the cardiology department in Soonchunhyang university hospital. Subjects were divided into 4 groups, a control group, a stable angina and unstable angina group and an acute myocardial infarction group. The clinical findings, TAS, inflammatory cytokines(P-selectin, MCP-1, IL-6), anti-inflammatory cytokines(IL-10), Homocysteine and CRP levels in each group were measured and compared. Results : The total number of study participants was 86 patients, with 26 patients in the control group, 21 patients with stable angina, 15 patients with unstable angina, and 24 patients with AMI. There were significant differences in the TAS among the 4 grouops. 1.7±0.51 mmol/L, 1.6±0.60 mmol/L, 1.4±0.20 mmol/L, 1.4±0.29 mmol/L respectively. IL-6 levels also showed a significant difference between groups, averaging 0.8±2.47 pg/ml, 2.7±3.77 pg/ml, 6.8±10.63 pg/ml, 10.9±17.43 pg/ml respectively. Homocysteine levels averaged 8.0±2.47 pg/ml, 6.8±10.63 pg/ml, 10.9±17.43 pg/ml restectively. Homocysteine levels averaged 8.0±1.0 μmol/L in the control group, 14.3±5.14 μmol/L in patients with stable angina, 16.0±4.66 μmol/L in patients with unstable angina, and 17.3±10.08 μmol/L in AMI patients. Conclusion : Compared to the control group, the TAS levels were significantly lower in patients with unstable angina and AMI. there was no difference between the control group and those with stable angina. IL-6 and homocysteine levels were also higher in patients with unstable angina and AMI. Therefore we concluded that measurements of TAS, IL-6 and homocysteine are useful in measuring the inflammatory index of coronary artery diseases and may be important factors in predicting the states and prognosis of cardiovascular disorders.

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