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      • KCI등재

        The impact of industry characteristics on firms’ export intensity

        Joana Reis,Rosa Forte 한국외국어대학교 국제지역연구센터 2016 International Area Studies Review Vol.19 No.3

        Several authors have studied the factors that influence a firm’s export performance, but few have addressed the relationship between industry characteristics and export intensity. The objective of the present study was to analyze the impact of industry characteristics on a firm’s export intensity, the latter a measure commonly used to assess export performance, seeking to add empirical evidence to this relatively neglected research area. Based on a sample of 19,504 Portuguese manufacturing firms, 7,930 of which were exporting, during the period 2010–2013, and using panel data estimation, the empirical results show that some industry characteristics (labor productivity, export orientation, concentration), as well as characteristics of the firm (labor productivity, size and age of the firm) are important determinants of a firm’s export intensity. It is concluded in particular that a firm’s export intensity is positively affected by the export orientation of the industry, as well as by the firm’s labor productivity, confirming the belief that firms and governments need to direct their policies towards increased productivity in order to improve competitiveness in foreign markets. It is argued that, in order to enhance the positive effects of these policies, the policies should be directed towards industries with the highest export focus.

      • KCI등재

        Buried Barrett’s Esophagus with High-Grade Dysplasia after Radiofrequency Ablation

        Joana Castela,Miguel Serrano,Susana Mão de Ferro,Daniela Vinha Pereira,Paula Chaves,António Dias Pereira 대한소화기내시경학회 2019 Clinical Endoscopy Vol.52 No.3

        Radiofrequency ablation therapy is an effective endoscopic option for the eradication of Barrett’s esophagus that appears to reduce therisk of esophageal cancer. A concern associated with this technique is the development of subsquamous/buried intestinal metaplasia,whose clinical relevance and malignant potential have not yet been fully elucidated. Fewer than 20 cases of subsquamous neoplasia afterthe successful radiofrequency ablation of Barrett’s esophagus have been reported to date. Here, we describe a new case of subsquamousneoplasia (high-grade dysplasia) following radiofrequency ablation that was managed with endoscopic resection. Our experiencesuggests that a meticulous endoscopic inspection prior to and after radiofrequency ablation is fundamental to reduce the risk of buriedneoplasia development.

      • The Trademark Tarnishment and the Compensation for Non-Pecuniary Damages of Commercial Companies

        ( Joana Crisostomo ) 한국EU학회 2013 Asia-Pacific Journal of EU Studies Vol.11 No.2

        This paper is about the possibility of awarding non-pecuniary damages to commercial companies, mainly focusing in cases of trademark dilution, especially tarnishment. Neither Portuguese nor Macanese legislations (the ones that will be analyzed in more detail), are clear about what kind of damage a company may suffer. This leads to different approaches from case to case, which create the undesirable result of also having different decisions made by the courts about similar situations. From a EU perspective, the EU Directive 2004/48/EC, on the enforcement of intellectual property rights, presents remedies which include the compensation for non-pecuniary damage, but it is still not clear whether this should apply to legal persons. The objective of this study is to ascertain whether this remedy is available in cases of trademark tarnishment regarding legal persons and to question whether a positive answer would introduce incoherence in national tort law systems.

      • Poster Session : PS 0272 ; Gastroenterology : Ogilvie Syndrome - Undiagnosed and Untreated but a Condition to Have in Mind

        ( Joana Malho Rodrigues ),( Debora Cardoso ),( Rita Ivo ),( Sofi A Serra ),( Margarida Proenca ),( Patricia Moniz ),( Arturo Botella ),( Susana Jesus ),( Candida Fonseca ),( Ana Leitao ),( Luls Campos 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Introduction: Ogilvie Syndrome (OS) is an acute colonic pseudo-obstruction with no mechanical cause underlying. The diagnosis is mainly clinical and radiological. Of unknown pathophysiology but in 95% associated with other pathologies such as infectious, cardiac, neurological among others. The treatment is based on decompression wih nasogastric tube(NGT), enteroclysis, laxative and procinetic therapies with neostigmine and erythromycine. In severely ill or complicated patients, endoscopic and surgical decompression may be indicated, even thought, mortality rates can be up to 40%. Clinical Cases: 1) 82 years old woman admitted with acute heart failure. Presented with abdominal distention and hydroaeric levels without relevant hydroelectrolyte disturbances. Lack of response to laxative and procinetic therapies. Computer tomography (CT) excluded obstructive lesions. After introduction of erythromycin intestinal transit was reestablished. 2) 87 years old man, admitted with community adquired pneumonia (CAP) who developed intestinal sub-oclusion with parcial recuperation after procinetics, NGT decompression and enteroclysis. CT: massive intestinal distention without obstruction. Hospitalization complicated with stroke, which lead to death. 3) 94 years old woman, admitted with CAP and acute renal lesion. Had maintained intestinal transit but, marked abdominal distention and pain. Transitory improvement after enteroclysis and NGT. CT showed transverse and sigmoid colon marked distention, without occlusive lesions. Although optimized therapy the patient progressed into anuria, multiorganic failure which lead to death. Conclusion: OS is a frequently undiagnosed clinical condition. Prompt diagnosis and treatment can predict a better outcome and are important to avoid complications such as intestinal perforation, ischaemia and peritonitis.

      • KCI등재
      • KCI등재

        Very Late-Onset Schizophrenia-Like Psychosis: A Case Report and Critical Literature Review

        Joana Regala,Francisco Moniz-Pereira 대한노인병학회 2023 Annals of geriatric medicine and research Vol.27 No.2

        Late-life psychosis presents a challenge, wherein a wide range of differential diagnoses should be considered. Very late-onset schizophrenia-like psychosis (VLOSLP) is a nosological entity that remains a conundrum. We provide a comprehensive literature review on the neurobiological underpinnings of VLOSLP. We describe a case that typifies the clinical presentation of VLOSLP. Although not pathognomonic, certain features, namely the two-stage progression of psychotic episode, partition delusions, multimodal hallucinations, and absent formal thought disorder or negative symptoms, are quite suggestive of VLOSLP. Several medical causes that might cause late-life psychosis, including neuroinflammatory/immunology diseases, were ruled out. Neuroimaging revealed basal ganglia lacunar infarctions along with chronic white matter small-vessel ischemic disease. The diagnosis of VLOSLP is based on clinical evidence, and the aforementioned clinical features support this diagnostic hypothesis. This case adds to the growing body of evidence pertaining to the relevance of cerebrovascular risk factors in the pathophysiology of VLOSLP, alongside age-specific neurobiological processes. We hypothesized that microvascular brain lesions disrupt the frontal-subcortical circuitry and uncover other core neuropathological processes. Future research should focus on identifying a specific biomarker that would allow clinicians to more accurately diagnose VLOSLP, differentiate it from other overlapping clinical entities such as dementia or post-stroke psychosis, and provide a tailored treatment for the patient.

      • Naming of Objects and Actions after Treatment with Phonological Components Analysis in Aphasia

        Joana Kristensson,Charlotta Saldert 한국언어재활사협회 2018 Clinical Archives of Communication Disorders Vol.3 No.2

        Objectives: To explore the effects of intensive treatment with phonological components analysis on naming of both objects and actions. Methods: Phonological components analysis (PCA) was used to treat two individuals with moderate or severe aphasia after stroke. A single case study design with chronological time series analysis was employed to explore the effects of treatment for a total of up to 20 hours comprising the naming of self-chosen objects and actions. Changes in confrontation naming ability were assessed repeatedly. In addition, generalisation of training effects was examined in connected speech in a picture description task as well as in ratings of functional communication skills as perceived by the participants and their next of kin. Results: An increase in correctly produced words for treated items with some generalisation to untreated items was demonstrated post-treatment in a participant with moderate mixed fluent aphasia and mostly phonological errors. Number of words and degree of informativeness in the picture description task also increased. Results remained at a 10-week follow-up. A participant with severe conduction aphasia and mainly semantic errors in the pre-training assessment also demonstrated a small increase in correct confrontation naming post-treatment. Some aspects of functional communication skills were rated slightly higher, but both participants perceived the negative impact of the aphasia to be greater post-treatment. Conclusions: Phonological component analysis may be used in training of both objects and actions. However, aphasia severity and underlying deficits most likely influence the results and further research is warranted to explore the training effects.

      • Young capillary vessels rejuvenate aged pancreatic islets

        Almaca, Joana,Molina, Judith,Arrojo e Drigo, Rafael,Abdulreda, Midhat H.,Jeon, Won Bae,Berggren, Per-Olof,Caicedo, Alejandro,Nam, Hong Gil National Academy of Sciences 2014 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.111 No.49

        <P><B>Significance</B></P><P>The regulation of blood glucose is a homeostatic process that declines with age, but it is unknown whether this disturbance is a consequence of intrinsic dysfunction of the regulatory organ, the pancreatic islet. In marked contrast to the widely held notion that the insulin-producing pancreatic beta cell loses function with wear and tear, and thus causes age-related disturbances in glucose homeostasis, we show that mouse and human beta cells are fully functional at advanced age. The pancreatic islet as an organ, however, is threatened by vascular senescence. Replacing the islet vasculature in aged islet grafts rejuvenates the islet and fully restores glucose homeostasis, indicating that islet blood vessels should be targeted to mitigate frail glucose homeostasis associated with aging.</P><P>Pancreatic islets secrete hormones that play a key role in regulating blood glucose levels (glycemia). Age-dependent impairment of islet function and concomitant dysregulation of glycemia are major health threats in aged populations. However, the major causes of the age-dependent decline of islet function are still disputed. Here we demonstrate that aging of pancreatic islets in mice and humans is notably associated with inflammation and fibrosis of islet blood vessels but does not affect glucose sensing and the insulin secretory capacity of islet beta cells. Accordingly, when transplanted into the anterior chamber of the eye of young mice with diabetes, islets from old mice are revascularized with healthy blood vessels, show strong islet cell proliferation, and fully restore control of glycemia. Our results indicate that beta cell function does not decline with age and suggest that islet function is threatened by an age-dependent impairment of islet vascular function. Strategies to mitigate age-dependent dysregulation in glycemia should therefore target systemic and/or local inflammation and fibrosis of the aged islet vasculature.</P>

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