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        Bidirectional corneo-conjunctival transposition for large and deep canine corneal wound healing

        박경미,Jiyi Hwang,고영석,김혜민,남원희 충북대학교 동물의학연구소 2022 Journal of Biomedical and Translational Research Vol.23 No.3

        This case report describes satisfactory correction of deep and large canine corneal ulcerations by application of bidirectional corneo-conjunctival transposition (CCT). A 12-year-old spayed female Maltese dog with a large corneal descemetocele, perforation, and blepharospasm of the right eye was referred to Chungbuk National University Veterinary Teaching Hospital. More than half of the thickness of the cornea was damaged, and the ulcer was progressive. On ophthalmic examination, menace response and dazzle reflex were absent. No corneal melting was observed. As the patient had large and deep corneal ulcers, traditional one-sided CCT was not sufficient to cover the wound lesion. To increase corneal transparency after recovery, we decided to perform bidirectional CCT from 12 o’ clock on the dorsal side to 7 o’ clock on the ventral side. The dog was medicated with topical eye drops, ofloxacin, atropine, and moxifloxacin before surgery. Debridement with a diamond burr was then performed around the descemetocele. Five weeks after surgery, the dazzle reflex was restored as the blood vessel receded from the cornea to the conjunctiva. Eight weeks after surgery, corneal transparency and corneal stability were gradually restored, but not completely. Bidirectional CCT provides structural support and helps corneal wound healing in large canine corneal ulceration.

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        Molecular detection and characterization of Acanthamoeba infection in dogs and its association with keratitis in Korea

        이수빈,Badriah Alkathiri,정지승,강난영,Jiyi Hwang,박상은,홍연철,박경미,이승헌 대한기생충학ㆍ열대의학회 2024 The Korean Journal of Parasitology Vol.62 No.1

        Acanthamoeba infection is associated with keratitis in humans; however, its associationwith keratitis in dogs remains unclear. To investigate this possibility, we collected 171conjunctival swab samples from dogs with eye-related diseases (65 with keratitis and106 without keratitis) at Chungbuk National University Veterinary Teaching Hospital, Korea, from August 2021 to September 2022. Polymerase chain reaction identified 9 samples (5.3%) as Acanthamoeba positive; of these, 3 were from dogs with keratitis (4.6%)and 6 were from dogs without keratitis (5.7%). Our results indicated no significant association between Acanthamoeba infection and keratitis, season, sex, or age. All Acanthamoeba organisms found in this study had the genotype T4, according to 18S ribosomal RNA analysis. Acanthamoeba infection in dogs might have only a limited association with keratitis.

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