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JinWon Noh,Hyunchun Park,Minji Kim,YoungDae Kwon,JinSeok Kim,Shieun Yu 대한신경정신의학회 2018 PSYCHIATRY INVESTIGATION Vol.15 No.1
Objective-This study investigated the mediation effect of stress between the experience of discrimination and life satisfaction among North Korean refugees who resettled in South Korea. The findings of the current study provide empirical evidence for the need of social interventions to mitigate adverse effects of stress on North Korean refugees who are subject to social discrimination on a daily basis. Methods-In this study, we included 500 subjects among 2,138 North Korean refugees who took refuge in South Korea in 2007. The interview started from April 6th 2009 and finished on May 25th 2009. We conducted moderator effect analysis with Path analysis was conducted because we confirm the experience of discrimination was affected by life satisfaction and stress can affected life satisfaction as a moderator. Results-The experience of discrimination significantly affects stress and stress significantly affects life satisfaction. However, the experience of discrimination was not directly related to life satisfaction. The more stress the study respondents experienced, the lower the life satisfaction they reported. Conclusion-The present finding suggests that the effects of discriminating experiences on the life satisfaction of North Korean refugees in South Korea were mediated by their own perceived stress.
JinWon Noh,HeeSoon Juon,Sanghoon Lee,YoungDae Kwon 대한신경정신의학회 2014 PSYCHIATRY INVESTIGATION Vol.11 No.3
Objective-The purpose of this study is to examine the relationship between substance use and depressive symptoms in a cohort of Koreans aged 45 years and older from a large, population-based study. Using the 2006 Korean Longitudinal Study of Aging, we estimated the prevalence of depressive symptoms and its association with smoking and alcohol use. Methods-Depressive symptoms were measured using the CES-D 10-item scale. Age, marital status, educational attainment, employment and any disability were the control variables. Because there were gender differences in smoking and alcohol use, we also performed a separate analysis by gender. Results-In the multivariable logistic regression, ex-drinkers were more likely to be depressed than non-drinkers (OR, 1.37; 95% CI, 1.08–1.74 for males; OR, 1.78; 95% CI, 1.23–2.57 for females). Compared to non-drinkers, males with moderate drinking habits (OR, 0.75; 95% CI, 0.63–0.90) were less likely to be depressed, whereas heavy male drinkers were more likely to be depressed (OR, 1.43; 95% CI, 1.07–1.91). Female smokers were more likely to be depressed than female non-smokers (OR, 2.07; 95% CI, 1.51–2.83). Conclusion-This study showed atypical pattern of relationship between smoking and depression and U-shaped relationship between depressive symptoms and alcohol consumption in male population. Both of these findings could be inferred from that these regional characteristics might be cross-sectional finding of chronologic transition result from a rapid rise of late life depression in Korea.
JinWon Noh,Hyunchun Park,YoungDae Kwon,InHye Kim,YoHan Lee,YoonJung Kim,SinGon Kim 대한신경정신의학회 2017 PSYCHIATRY INVESTIGATION Vol.14 No.6
Objective-According to previous social survey, a high number of North Korean refugees (NKRs) in South Korea had suicidal ideation. The purpose of this study is to examine the related factors for suicidal ideation among NKRs by gender in South Korea. Methods-We examined the sample of NKRs, 701 subjects (men=160, women=-541) residing in South Korea, the participants were enrolled from October 2008 to May 2014. The related factors with suicidal ideation in NKRs were analyzed via a logistic regression analysis. Results-Refugee women were more likely to have suicidal ideation than men were. Although thoughts of suicide do not necessarily mean that they will follow through, however, there is an association that the higher rate of suicide also results in a higher rate of attempted suicide. In both genders, they tended to think more frequently about suicide who had stayed in South Korea for more than 5 years. In addition, higher frequencies of suicidal ideation also associated with higher level of perceived stress in both genders. Conclusion-The gender difference should be addressed when designing suicide prevention interventions among the North Korean population in South Korea.
Effect of structural distortion on ferrimagnetic order inLu1−xLxFe2O4(L=Yand Er;x=0.0, 0.1, and 0.5)
Noh, Han-Jin,Sung, Hojin,Jeong, Jinwon,Jeong, Jinhwan,Kim, Sung Baek,Kim, Jae-Young,Kim, J. Y.,Cho, B. K. American Physical Society 2010 Physical review. B, Condensed matter and materials Vol.82 No.2
Bioactive Lipids and Their Derivatives in Biomedical Applications
( Jinwon Park ),( Jaehyun Choi ),( Dae-duk Kim ),( Seunghee Lee ),( Bongjin Lee ),( Yunhee Lee ),( Sanghee Kim ),( Sungwon Kwon ),( Minsoo Noh ),( Mi-ock Lee ),( Quoc-viet Le ),( Yu-kyoung Oh ) 한국응용약물학회 2021 Biomolecules & Therapeutics(구 응용약물학회지) Vol.29 No.5
Lipids, which along with carbohydrates and proteins are among the most important nutrients for the living organism, have a variety of biological functions that can be applied widely in biomedicine. A fatty acid, the most fundamental biological lipid, may be classified by length of its aliphatic chain, and the short-, medium-, and long-chain fatty acids and each have distinct biological activities with therapeutic relevance. For example, short-chain fatty acids have immune regulatory activities and could be useful against autoimmune disease; medium-chain fatty acids generate ketogenic metabolites and may be used to control seizure; and some metabolites oxidized from long-chain fatty acids could be used to treat metabolic disorders. Glycerolipids play important roles in pathological environments, such as those of cancers or metabolic disorders, and thus are regarded as a potential therapeutic target. Phospholipids represent the main building unit of the plasma membrane of cells, and play key roles in cellular signaling. Due to their physical properties, glycerophospholipids are frequently used as pharmaceutical ingredients, in addition to being potential novel drug targets for treating disease. Sphingolipids, which comprise another component of the plasma membrane, have their own distinct biological functions and have been investigated in nanotechnological applications such as drug delivery systems. Saccharolipids, which are derived from bacteria, have endotoxin effects that stimulate the immune system. Chemically modified saccharolipids might be useful for cancer immunotherapy or as vaccine adjuvants. This review will address the important biological function of several key lipids and offer critical insights into their potential therapeutic applications.
Frequency-Dependent UWB Channel Characteristics in Office Environments
Jinwon Choi,Noh-Gyoung Kang,Yu-Suk Sung,Jun-Sung Kang,Seong-Cheol Kim IEEE 2009 IEEE Transactions on Vehicular Technology VT Vol.58 No.7
<P>This paper reports frequency-dependent ultrawideband (UWB) channel characteristics. Measurements were performed in 103 receiver locations of six different office environments. From the measured data, the effect of frequency on the path-loss properties of a UWB signal is analyzed. After analyzing the path-loss behavior to propagation environments, the path-loss exponent variation models are developed in various environments as a function of frequency. Based on these models, path-loss prediction is performed, and the accuracy of the prediction is compared with those of existing path-loss models. In addition, the frequency-dependent UWB channel correlation characteristics are investigated. For the frequency correlation statistics of the UWB channel, double-slope models representing correlation coefficients are established with and without line-of-sight (LOS) paths. Using these correlation models, a channel gain estimation algorithm is proposed. The performance of the proposed estimation algorithm is evaluated with estimation parameters, and it is confirmed that the proposed estimation algorithm has better performance than the conventional algorithm using a linear interpolation algorithm.</P>