Research on the Design of CORDIC Vector Magnitude Calculator by using Model-Based Design

Jianying Cao,Xiaoxia Zheng,Yang Nie 보안공학연구지원센터 2015 International Journal of Signal Processing, Image Vol.8 No.12

Vector magnitude calculation is significant in the QR-algorithm by Coordinate Rotation Digital Computer (CORDIC), which is increasingly used in adaptive applications. However, its hardware implementation is extremely difficult. In this paper, a fixed point CORDIC system is constructed to compute the magnitude of a vector by using Model-Based Design. The simulation results show that the proposed method of CORDIC vector magnitude calculator is not only simple in structure and easy to implement, and can improve the speed of operation with good scalability.

Development of polymorphic EST-SSR markers by sequence alignment in Frankliniella occidentalis (Pergande)

Jiani Liu,Zheng-Yue Li,Xiaoyan Chen,Heping Huang,Furong Gui 한국응용곤충학회 2014 Journal of Asia-Pacific Entomology Vol.17 No.3

The western flower thrips, Frankliniella occidentalis, is the most economically important agronomic pest withinThysanoptera because it is both a direct pest of horticulture crops and an efficient vector of plant viruses. Sixty-seven polymorphic SSR loci were identified in the contigs (containing redundant ESTs) generated byassembling 13,839 F. occidentalis ESTs from the public sequence database. Nineteen SSR markers exhibited polymorphismamong 860 samples from43 F. occidentalis populations,with alleles per SSR marker ranging fromtwoto eight, the effective number of alleles (Ne) range from 0.73 to 2.64; the observed (Ho) and expected (He) heterozygositiesranged from 0.09 to 0.77 and 0.12 to 0.96, respectively. The PIC values were from 0.24 to 0.73. AMOVA revealed most genetic variation resided within, rather than between, greenhouse and field isolates. The Mantel test showed no significant differences between genetic and geographical distances. We demonstratedthe value of mining the redundant sequences in public sequence databases for the development of polymorphicSSR markers, which can be used for better understanding population variation and spreading of the invasive pestF. occidentalis.

Integrated analysis of DNA methylome and transcriptome reveals SFRP1 and LIPG as potential drivers of ovarian cancer metastasis

Jiani Yi,Mengting Wu,Zhihong Zheng,Qing Zhou,Xufan Li,Yan Lu,Pengyuan Liu 대한부인종양학회 2023 Journal of Gynecologic Oncology Vol.34 No.6

Objective: More than 75% of ovarian cancer patients are diagnosed at advanced stages and die of tumor cell metastasis. This study aimed to identify new epigenetic and transcriptomic alterations associated with ovarian cancer metastasis. Methods: Two cell sublines with low- and high-metastasis potentials were derived from the ovarian cancer cell line A2780. Genome-wide DNA methylome and transcriptome profiling were carried out in these two sublines by Reduced Representation Bisulfite Sequencing and RNA-seq technologies. Cell-based assays were conducted to support the clinical findings. Results: There are distinct DNA methylation and gene expression patterns between the two cell sublines with low- and high-metastasis potentials. Integrated analysis identified 33 methylation-induced genes potentially involved in ovarian cancer metastasis. The DNA methylation patterns of two of them (i.e., SFRP1 and LIPG) were further validated in human specimens, indicating that they were hypermethylated and downregulated in peritoneal metastatic ovarian carcinoma compared to primary ovarian carcinoma. Patients with lower SFRP1 and LIPG expression tend to have a worse prognosis. Functionally, knockdown of SFRP1 and LIPG promoted cell growth and migration, whereas their overexpression resulted in the opposite effects. In particular, knockdown of SFRP1 could phosphorylate GSK3β and increase β-catenin expression, leading to deregulated activation of the Wnt/β-catenin signaling. Conclusion: Many systemic and important epigenetic and transcriptomic alterations occur in the progression of ovarian cancer. In particular, epigenetic silencing of SFRP1 and LIPG is a potential driver event in ovarian cancer metastasis. They can be used as prognostic biomarkers and therapeutic targets for ovarian cancer patients.

A Comparative Study on the Insulation Ageing of 10 kV XLPE Cable via Accelerated Electrical Test and Accelerated Water Tree Test

Li Weiwei,Zheng Wenyue,Ren Lulu,Li Huan,Zhao Xuetong,Wang Can,Li Jianying 대한전기학회 2022 Journal of Electrical Engineering & Technology Vol.17 No.1

Medium and high voltage XLPE cables were widely used in urban distribution network. The electric-thermal eff ect of the cable conductor and water in the running environment are two important factors that cause ageing of cable insulating material. In this work, accelerated electrical test (AET) and accelerated water tree test (AWTT) on 10 kV XLPE cable were carried out for 1440 h, 2880 h and 4320 h, respectively. The physicochemical and dielectric properties of both aged and unaged XLPE samples were tested. Physicochemical investigation of Fourier Transform Infrared (FTIR) spectroscopy and X-Ray Diff raction (XRD) show that higher carbonyl groups index, and lower crystallinity of the XLPE insulating materials were generated in AWTT process than that in AET process. The thermal decomposition process of the AWTT XLPE are complicated, presenting a multi-peak phenomenon in the diff erential thermogravimetry (DTG) curve. The insulating strength of the samples after AWTT is monotonically decreased from 23.03 kV to 21.74 kV with ageing time. The dielectric properties show that the permittivity and dielectric loss of AWTT samples increased more severely than that of AET samples, with a new dielectric relaxation peak appearing at around 100 Hz. The combination of physicochemical and dielectric results reveals that AWTT process leads to more serious degradation for XLPE insulating materials. A schematic illustration is given to elucidate the development of micro defects in XLPE during the AET and AWTT processes.

The Morphological Evaluation of the Cervical Muscle in Patients With Basilar Invagination: A Magnetic Resonance Imaging-Based Study

Junyu Lin,Panjie Xu,Jianying Zheng,Zhang Zefan,Jingwen Tan,Hang Xiao,Siyan Yu,Qingan Zhu,Wei Ji 대한척추신경외과학회 2023 Neurospine Vol.20 No.3

Objective: To investigate the characteristics of functional muscle and muscle size in patients with basilar invagination (BI) and explore the effects of atlantoaxial dislocation. Methods: Eighty BI patients (BI group) and 80 age- and sex-matched asymptomatic people (control group) were included. Axial T2 magnetic resonance imaging image was used to measure the cross-sectional area (CSA) and functional CSA (FCSA). The sternocleidomastoid (SCM), longus capitis and longus colli (LCap & LC), trapezius (Trap), splenius capitis (SpCap), splenius cervicis (SpC), semispinalis capitis (SSCap), semispinalis cervicis (SSC), multifidus (MS), levator scapulae (LS) and posterior deep layer muscles (PDLM) were evaluated. Correlations between age, atlantodental interval (ADI), Chamberlain distance and muscles were observed. Results: BI group (39.4 ± 18.4 years; 33 males/47 females) exhibited significantly lower FCSA/CSA ratios than the control group in all extensor and flexor muscles, and presented smaller CSAs on the right and left Trap, SSC, LS, SCM, and left LCap & LC. FCSA/CSA ratios were significantly lower in BI patients with dislocation on the right Trap, SpCap, SpC, SSCap, MS, LS, LCap & LC, and PDLM, and the left SSCap, MS, and LCap & LC than in patients without deformity. Additionally, functional muscles of all parameters decreased with age in BI patients. Excluding children, the Trap, SpC, MS, and LS muscle sizes of BI patients tended to increase with age. ADI and Chamberlain distance tended to correlate negatively with FCSA/CSA ratio. Conclusion: The BI patients, especially those with atlantoaxial dislocation, had less functional muscles compared with the control group. Moreover, their functional muscles decreased with age more obviously.