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Chemical Components of Dendrobium polyanthum
Jiang-Miao Hu,You-Xing Zhao,Ze-Hong Miao,Jun Zhou 대한화학회 2009 Bulletin of the Korean Chemical Society Vol.30 No.9
A new tetrahydroanthracene, 3,6,9-trihydroxy-3,4-dihydroanthracen-1(2H)-one (1), six phenolics, moscatilin (2), gigantol (3), batatasin (4), moscatin (5), 9,10-dihydromoscatin (6), 10-dihydrophenanthrene-2,4,7-triol (7), and a sesquiterpenoid, corchoionoside C (8), together with two sterols β-sitosterol (9) and daucosterol (10), were isolated from the stems of Dendrobium polyanthum. Compounds 1 and 2 were assessed for cytotoxic activity against two human tumor cell lines (A549 and HL-60).
Chemical Components of Dendrobium polyanthum
Hu, Jiang-Miao,Zhao, You-Xing,Miao, Ze-Hong,Zhou, Jun Korean Chemical Society 2009 Bulletin of the Korean Chemical Society Vol.30 No.9
A new tetrahydroanthracene, 3,6,9-trihydroxy-3,4-dihydroanthracen-1(2H)-one (1), six phenolics, moscatilin (2), gigantol (3), batatasin (4), moscatin (5), 9,10-dihydromoscatin (6), 10-dihydrophenanthrene-2,4,7-triol (7), and a sesquiterpenoid, corchoionoside C (8), together with two sterols $\beta$-sitosterol (9) and daucosterol (10), were isolated from the stems of Dendrobium polyanthum. Compounds 1 and 2 were assessed for cytotoxic activity against two human tumor cell lines (A549 and HL-60).
Liu Yan-ju,Jiang Jin-gang,Miao Feng-juan,Tao Bai-rui,Zhang Hong-lie 보안공학연구지원센터 2014 International Journal of Grid and Distributed Comp Vol.7 No.5
This paper presents a fuzzy normal estimate for mass point clouds of irregular models in reconstruction. The irregular model is complex object that some part is smooth and some parts are irregular including sharp features. Therefore, we put kNN and curvature of mass point clouds to fuzzy inference system to divide the kind of point clouds and the output of FIS can determine which part of tooth point clouds belong to. For different kinds point clouds, corresponding algorithm is given. Point clouds in the smooth area are estimated normal by PCA directly and ones in other regions of thin or sharp area are estimated by checker and attach points. This method is simpler than those complex methods used on the whole point clouds directly. The experiment results show that much time is saved and surface reconstruction is very fine than PCA and WLOP.
Insect-specific microRNA involved in the development of the silkworm Bombyx mori
Yong Zhang,Xue Zhou,Xie Ge,Jiang-Hao Jiang,Mu-Wang Li,Shi-Hai Jia,Xiao-Nan Yang,Yun-Chao Kan,Xue-Xia Miao,Guo-Ping Zhao,Fei Li,Yong-Ping Huang 한국응용곤충학회 2009 한국응용곤충학회 학술대회논문집 Vol.2009 No.10
MicroRNAs (miRNAs) are endogenous non-coding genes that participate in post-transcription regulation by either degrading mRNA or blocking its translation. It is considered to be very important in regulating insect development and metamorphosis. Insects are the largest group of animals and are extremely valuable in biological and agriculture research. Insects are also important pests to human health and agriculture, and efforts are necessary protect both humans and plants from disease and damage. Despite their importance, insects lag behind mammals, nematodes, and plants in miRNA research. At present, only 279 insect miRNAs have been identified from Drosophila melanogaster, Anopheles gambiae, Apis mellifera, Bombyx mori, and D. pseudoobscura in miRBase, and most of these miRNAs were computationally predicted without experimental validation. Functional analysis of insect miRNAs has only been conducted in D. melanogaster.
Qian Ding,Xiao-Li Xie,Miao-Miao Wang,Jie Yin,Jin-Mei Tian,Xiao-Yu Jiang,Di Zhang,Jing Han,Yun Bai,Zi-Jin Cui,Hui-Qing Jiang 생화학분자생물학회 2019 Experimental and molecular medicine Vol.51 No.-
The clearance of activated hepatic stellate cells (HSCs) by apoptosis is critical for the reversibility of hepatic fibrosis. Mitochondrial homeostasis is regulated by mitophagy, which is an efficient way of clearing injured mitochondria that plays an important role in apoptosis. However, the role of mitophagy in apoptosis in HSCs and hepatic fibrosis is still unclear. Here, we show that mitophagy is enhanced in parallel with increased apoptosis in hepatic stellate cells during the reversal of hepatic fibrosis. The inhibition of mitophagy suppressed apoptosis in HSCs and aggravated hepatic fibrosis in mice. In contrast, the activation of mitophagy induced apoptosis in HSCs. Furthermore, we confirmed that BCL-B, which is a member of the BCL-2 family, is a regulator mediating mitophagy-related apoptosis. The knockdown of BCL-B resulted in increased apoptosis and mitophagy in HSCs, while the overexpression of BCL-B caused the opposite effects. BCL-B inhibited the phosphorylation of Parkin (a key regulator of mitophagy) and directly bound phospho-Parkin. Altogether, enhanced mitophagy promotes apoptosis in HSCs during the reversal of hepatic fibrosis. BCL-B suppresses mitophagy in HSCs by binding and suppressing phospho-Parkin, thereby inhibiting apoptosis. BCLB- dependent mitophagy is a new pathway for the regulation of apoptosis in HSCs during the regression of hepatic fibrosis
Semantic Behavior of Indexed Co-inductive Data Type in Fibrational Setting
Miao De-cheng,Xi Jian-qing,Jiang Chang-jin,Liang Yong-lin 보안공학연구지원센터 2016 International Journal of u- and e- Service, Scienc Vol.9 No.6
Traditional methods such as category theory and coalgebra have some drawbacks to analyze semantic behavior of indexed co-inductive data type. Aiming at the problem above, this paper explored indexed co-inductive data type in programming by Fibrations theory. Our main work was that we firstly made some basic logical structures of indexed co-inductive data type over a fibration such as truth and quotient functor; using endo-functor in base categories and their equation-preserving lifting in total categories, then we analyzed semantic behavior of indexed co-inductive data type; at last we briefly introduced applications of Fibrations theory on indexed co-inductive data type by example. Compared with traditional methods, brief descriptions and flexible expansibility of Fibrations theory can analyze semantic behavior of indexed co-inductive data type accurately, and superior abstractness of Fibrations theory doesn’t rely on particular computing environments to compute semantics.
Investor Sentiment, Product Features, and Advertising Investment Sensitivities
Miao Luo,Daniel X. Jiang,Jun Cai 한국증권학회 2014 Asia-Pacific Journal of Financial Studies Vol.43 No.6
Investor sentiment plays an important role, affecting firm level advertising expenditures. Weprovide evidence that financially constrained firms exhibit lower advertising investment-cashflow sensitivity and higher advertising investment-q sensitivity during high sentiment periods. The patterns are driven mainly by those firms facing financial constraints. More importantly, weidentify several product features that also affect advertising investment sensitivities. Sorting onproduct features generates investment sensitivities that closely resemble those of sorting onfinancial constraint measures. We design empirical analyses to provide clean tests of the cost-of-external-financing-based and product-feature-based explanations underlying the variation inadvertising investment sensitivities.
Concurrent Engineering Based Collaborative Design Under Network Environment
Jiang Gongliang,Huang Hong-Zhong,Fan Xianfeng,Miao Qiang,Ling Dan The Korean Society of Mechanical Engineers 2006 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.20 No.10
Concurrent Engineering (CE) is a popular method employed in product development. It treats the whole product design process by the consideration of product quality, cost, rate of progress, and demands of customers. The development of computer and network technologies provides a strong support to the realization of CE in practice. Aiming at the characteristics of CE and network collaborative design, this paper built network collaborative design system frame. Through the analysis of the network collaborative design modes based on CE, this paper provided a novel network collaborative design integration model. This model can integrate the product design information, design process, and knowledge. Intelligent collaboration was considered in the proposed model. The study showed that the proposed model considered main factors such as information, knowledge, and design process in collaborative design. It has potential application in CE fields.